Journal Club and Cardiovascular Course

Presentation during one of the journal clubs

A.  Click here to download an example of an outline of the graduate course: MOLECULAR MECHANISMS OF CARDIOVASCULAR DISEASE – GMS BI 778-A1

B. Journal Club

As of 2014, trainees participation and presentation in Journal Clubs are often linked to topics presented at the CVI Seminar Series. Presentations alternate between Work in Progress and Discussion of published research. Journal Clubs are held every three weeks so that each trainee presents at least three times per year.

Presenter: Shinobu Matsuura

Date: 1/14/14

Title of Talk: WP, Collagen adhesion in platelets are affected by LOX activity

Presenter: Rongjuan Mi

Date: 1/21/14

Title of Talk: WP, Megakaryocyte Biology and LOX

Presenter: Chad Mayer

Date: 2/4/14

Title of Talk: WP, Shiga-toxin producing E.coli and the Endothelium

Presenter: Tim Calamaras

Date: 2/18/14

Title of Talk: WP, Oxidative post-translational modifications of LKB1 in the heart

Presenter: Melissa Thompson

Date: 3/11/14

Title of Talk: WP

Presenter: Shenia Patterson

Date: 3/25/14

Title of Talk: WP, The Effects of the A2bAR on Hematopoiesis and Vasculature

Presenter: Anna Eisenstein

Date: 4/8/14

Title of Talk: Practice Thesis Defense

Presenter: Kiana Mahdaviana

Date: 4/29/14

Title of Talk: WP

Presenter: Shinobu Matsuura

Date: 5/20/14

Title of Talk: WP, Collagen adhesion in platelets are affected by LOX activity

Presenter: David Backman

Date: 6/3/14

Title of Talk: WP, Bioengineering and Vasculature Models

Presenter: 2 invited Post-docs

Date: 6/24/14

Title of Talk: TBA

Journal Clubs by Trainees and Their Invitees (2012-2013)

Presenter: Dr. Milka Koupenova

Date: 1/10/12

Title of Talk: TLR7 and Thrombocytopenia

Presenter: Shannon Carroll

Date: 1/17/12

Title of Talk: Journal Club: In vivo fate mapping identifies mesenchymal progenitor cells

Presenter: Anna Eisenstein

Date: 1/31/12

Title of Talk: Tier II presentation: Role of the A2b Adenosine Receptor in Adipocyte Differentiation

Presenter: Tim Calamaras

Date: 2/14/12

Title of Talk: Oxidative post-translational modifications of LKB1 in the heart

Presenter: Jennifer Parker

Date: 2/21/12

Title of Talk: WP, Vascular Injury and Adiponectin

Presenter: Nadia Krasner

Date: 3/13/12

Title of Talk: WP, GLP-1 and Atherogenesis

Presenter: Hillary J.C.

Date: 3/27/12

Title of Talk: A2b AR, cAMP, and Insulin Secretion

Presenter: Shinobu Matsuura

Date: 4/10/12

Title of Talk: Role of Lysyl Oxidase in Megakaryocyte biology

Presenter: Hillary J.C.

Date: 4/24/12

Title of Talk: A2b AR and Modulation of Inflammatory Driven Diseases: Atherosclerosis and Type 2 Diabetes

Presenter: Daniel Backman

Date: 5/8/12

Title of Talk: WP, Bioengineering and Vasculature Models

Presenter: Anna Eisenstein

Date: 5/29/12

Title of Talk: WP, A2bAR and Adipogenesis

Presenter: Shannon Carroll

Date: 6/19/12

Title of Talk: WP, A2bAR and Wnt Signaling

Presenter: Shinobu Matsuura

Date: 7/10/12

Title of Talk: WP, Megakaryocyte biology

Presenter: Chad Mayer

Date: 9/4/12

Title of Talk: WP, Shiga-toxin producing E.coli and the Endothelium

Presenter: Anna Eisenstein

Date: 9/11/12

Title of Talk: WP, CD68 Project

Presenter: Tim Calamaras+ Shinobu Matsuura

Date: 10/02/12

Title of Talk: WP, Oxidative post-translational modifications of LKB1 in the heart/ Megakaryocyte biology

Presenter: Nadia Krasner

Date: 10/30/12

Title of Talk: JC

Presenter: Daniel Backman

Date: 11/06/12

Title of Talk: WP, Engineering devices to measure smooth muscle contractile forces

Presenter: Jennifer Parker-Duffen

Date: 11/27/12

Title of Talk: WP, Career opportunities in cardiovascular biology: an industry perspective

Presenter: Shannon Carroll

Date: 12/04/12

Title of Talk: WP, The A2b AR promotes MSC differentiation

Presenter: Shenia Peterson

Date: 12/18/12

Title of Talk: WP, The Effects of the A2bAR on Hematopoiesis

Presenter: Tim Calamaras

Date: 1/8/13

Title of Talk: WP, Heart Failure and Oxidative Stress

Presenter: Chad Mayer

Date: 1/22/13

Title of Talk: WP, Shiga-toxin producing E.coli and the Endothelium

Presenter: Anna Eisenstein

Date: 2/5/13

Title of Talk: WP, The Role of A2b Adenosine Receptor in Fat Differentiation

Presenter: Jennifer Parker-Duffen

Date: 2/19/13

Title of Talk: WP, Adiponectin and Vascular Disease

Presenter: Shinobu Matsuura

Date: 2/26/13

Title of Talk: WP, LOX in the control of platelet size

Presenter: Rongjuan Mi

Date: 3/5/13

Title of Talk: WP, Megakaryocyte Biology

Presenter: Shannon Carroll

Date: 3/19/13

Title of Talk: Thesis Practice

Presenter: Jennifer Parker-Duffen

Date: 4/9/13

Title of Talk: Thesis Practice

Presenter: Shenia Patterson

Date: 4/23/13

Title of Talk: WP, Update: The Effects of the A2bAR on Hematopoiesis

Presenter: Daniel Backman

Date: 5/7/13

Title of Talk: WP, Bioengineering and Vasculature Models

Presenter: Nadia Krasner

Date: 5/21/13

Title of Talk: WP, GLP-1 and Atherogenesis

Presenter: Chad Mayer

Date: 6/11/13

Title of Talk: WP, Shiga-toxin producing E.coli and the Endothelium

Presenter: Anna Eisenstein

Date: 6/25/13

Title of Talk: WP, The Role of A2b Adenosine Receptor in Fat Differentiation

Presenter: Tim Calamaras

Date: 7/9/13

Title of Talk: WP, Heart Failure and Oxidative Stress

Presenter: Shinobu Matsuura

Date: 7/16/13

Title of Talk: WP, Collagen adhesion in platelets are affected by LOX

Presenter: Rongjuan Mi

Date: 7/30/13

Title of Talk: WP, Megakaryocytes and LOX

Presenter: Anna Eisenstein

Date: 9/3/13

Title of Talk: Pre-Thesis Meeting Practice

Presenter: Kiana Mahdaviani

Date: 9/17/13

Title of Talk: WP

Presenter: Melissa Thompson

Date: 10/01/13

Title of Talk: WP

Presenter: Shenia Patterson

Date: 10/15/13

Title of Talk: WP

Presenter: Chad Mayer

Date: 10/29/13

Title of Talk: WP

Presenter: Daniel Backman

Date: 11/12/13

Title of Talk: WP

Presenter: Tim Calamaras

Date: 11/26/13

Title of Talk: WP

Presenter: Shinobu Matsuura

Date: 12/3/13

Title of Talk: WP

Journal Clubs by Trainees and Their Invitees (2010-2011)

Presenter: Shannon Carroll

Date: 1/19/10

Title of Talk: “The Potential Role of A2b AR in Bone Injury”

Presenter: Hillary Johnston-Cox

Date: 1/26/10

Title of Talk: “Adenosine: Chemotaxis and BM MSCs”

Presenter: Nikolaos Papadantonakis

Date: 2/23/10

Title of Talk:  “Generation of a GFP tubulin platelet-specific mouse”

Presenter: Milka Koupenova-Zamor

Date: 3/16/10

Title of Talk: “The Role of A2b AR in Vascular Function”

Presenter: Idowu Akinsheye

Date: 4/13/10

Title of Talk: “Genetic and Molecular Regulation of HBG gene expression in patients with Sickle Cell Disease”

Presenter: Olga Sazonova

Date: 4/27/10

Title of Talk: “Matrix mechanics and cell density modulate vascular smooth muscle cell gene and protein expression”

Presenter: Shannon Carroll

Date: 5/4/10

Title of Talk:  “Control of Mesenchymal Cell Differentiation by Adenosine Receptors”

Presenter: Hillary Johnston-Cox

Date: 5/11/10

Title of Talk:  “A2B AR: Therapeutic Potential in Liver Disease and Potential Role in Glucose /Insulin Homeostasis”

Presenter: Qyana Griffith

Date: 6/8/10

Title of Talk:  “Interface of Infectious Disease and Cardiovascular Disease”

Presenter: Larry Luchsinger

Date: 6/22/10

Title of Talk:  “Control of vascular collagen”

Presenter: Milka Koypenova-Zamor

Date: 7/13/10

Title of Talk:  “Control of obesity & atherosclerosis by A2b AR”

Presenter: Jennifer Parker

Date: 9/21/10

Title of Talk: Anti-inflammatory Effects of Adiponectin on Macrophages – Work in Progress

Presenter: Matt Mitsche

Date: 9/28/10

Title of Talk:  Insights into Lipoprotein Assembly and Remodeling from Drop Tensiometry

Presenter: Hillary Johnston-Cox

Date: 10/05/10

Title of Talk: A2B AR: Link Between Insulin Resistance and Inflammation

Presenter: Shannon Carroll

Date: 10/19/10

Title of Talk:  The Role of the A2bAR/cAMP in MSC Differentiation to Osteoblasts and Chondrocytes: Work in Progress

Presenter: Alexia Eliades

Date: 11/09/10

Title of Talk: Work in Progress: Effect of Lox and Lox-PP in Megakaryocyte Maturation and Development: Implication in Myelofibrosis

Presenter: Larry Luchinger

Date: 11/30/10

Title of Talk: The Myocardin Related Transcription Factor A (MRTF-A) Transactivates Type I Collagen in Lung Myofibroblasts

Presenter: Milka Koupenova-Zamor

Date: 12/07/10

Title of Talk: The Role of the A2b AR in the Metabolic Syndrome and Cardiovascular Tone

Presenter: Idowu Akinsheye

Date: 12/14/10

Title of Talk:  Sickle Cell Anemia and Vascular Dysfunction: The Nitric Oxide Connection

Presenter: Hongjie Chen

Date: 1/11/11

Title of Talk: Functional Significance of VSMC  Polyploidy

Presenter: Shakun Karki

Date: 1/25/11

Title of Talk: Regulation of Adiponectin in Fat Cells

Presenter: Olga Sazonova

Date: 2/01/11

Title of Talk: TBA

Presenter: Milka Koupenova, Hillary J.C., and Dr. Shirihai’s Group

Date: 1/25/11

Title of Talk: Role of A2b Adenosine Receptor in Insulin, Glucose and Lipid Metabolism

Presenter: Shakun Karki

Date: 2/1/11

Title of Talk: Transcriptional regulation of adiponectin

Presenter: Anna Eisenstein

Date: 2/8/11

Title of Talk: The Role of A2b Adenosine Receptor in Fat Differentiation and Implications in Metabolic Syndrome

Presenter: Jennifer Parker

Date: 3/1/11

Title of Talk: Adiponectin and Vascular Disease

Presenter: Shannon Carroll

Date: 3/15/11

Title of Talk: The Role of A2b Adenosine Receptor in Bone Injury and Repair

Presenter: Alexia Eliades

Date: 4/5/11

Title of Talk: Lysyl oxidase: a novel regulator of megakaryocyte lineage expansion

Presenter: Matt Mitsche and Idowu Akinsheye

Date: 4/26/11

Title of Talk: Insights into Triglyceride-Rich Lipoprotein Assembly From Drop Tensiometry and TBD

Presenter: Olga Sazonova

Date: 5/10/11

Title of Talk: VEGF and Vascular Disease

Presenter: Hillary J.C.

Date: 5/31/11

Title of Talk: The A2b Adenosine Receptor: Novel Role in Beta-cell function

Presenter: Anna Eisenstein and Shannon Carroll

Date: 7/26/11

Title of Talk: A2b AR: Fat and Bone Metabolism

Presenter: Tim Calamaras and Daniel Backman

Date: 9/27/11

Title of Talk: Bioengineering and Vasculature Models; Heart Failure and Oxidative Stress

Presenter: Hillary J.C.

Date: 10/11/11

Title of Talk: The Role of A2b AR in Glucose and Insulin Homeostasis

Presenter: Anna Eisenstein

Date: 10/25/11

Title of Talk: The Role of A2b AR in Fat Differentiation

Presenter: Nadia Krasner

Date: 11/8/11

Title of Talk: GLP-1 and Atherogenesis

Presenter: Jennifer Parker

Date: 11/8/11

Title of Talk: Adiponectin and Vascular Disease

Presenter: Dr. Victoria Herrera

Date: 11/15/11

Title of Talk: Nanoscience in Cardiovascular Biology

Presenter: Shannon Carroll

Date: 11/29/11

Title of Talk: The A2b AR promotes MSC differentiation to Osteoblasts and Bone Formation

Presenter: Shinobu Matsuura

Date: 12/20/11

Title of Talk: Lysyl Oxidase and Megakaryocyte Expansion and Bone Marrow Fibrosis

Journal Clubs by Trainees and Their Invitees (2008-2009)

Presenter:  Philip Trackman

Date:  1/16/08

Title of talk:  Lysil oxidase in the vasculature

Presenter:  Donald J. McCrann

Date:  2/5/08

Title of talk:  Practice of talk for thesis committee and defense: Regulation of polyploidy in the platelet and vascular lineages

Presenter:  Milka Koupenova

Date:  2/26/08

Title of talk:  Mouse models of atherosclerosis

Presenter:  Dr. Hongjie Chen (Cardiovascular Post-doc)

Date:  3/18/08

Title of talk:  The contribution of macrophage TNF-a during vascular injury

Presenter:  Dr. Dan Yang (invited Post Doc)

Date:  4/8/08

Title of talk:  The CXCR4 / SDF-1 axis and recruitment of progenitor cells to injured vessels

Presenter: Christopher Sullivan

Date: 5/6/08

Title of talk:  Serum Amyloid A: Control of atherosclerotic properties

Presenter:  Kristen Park

Date:  6/3/08

Title of talk:KO models and application to ion channel regulation in the vasculature

Presenter:  Alexia Eliades

Date:  7/29/08

Title of talk:  NADPH Oxidases

Presenter:  Dr. Katya Ravid (PI)

Presenter:  Cynthia St. Hilaire

Date:  8/08/08

Title of talk:  The vascular A2b adenosine receptor is regulated by oxidative stress

Date:  9/17/08

Title of talk:  Report on Purine Meeting (Copenhagen): Cardiovascular aspects

Presenter: Dr. Nikolaos Papadantonakis

Date:  10/28/08

Title of talk:  Cell Cycle Control: Computational approaches

Presenter:  Dr. Holger

Date:  11/4/08

Title of talk:  The tissue protecting effects of purine receptors

Presenter:  Dr. Alan Michelson

Date:  12/2/08

Title of talk:  Platelets and thrombosis: from basic mechanisms to the clinic

Presenter:  Larry Luchsinger

Date:  12/16/08

Title of talk:  Control of MHC and collagen (Biochemistry Graduate Student Day)

Presenter: Hongjie Chen, PhD

Date: 1/27/09

Title of talk: The A2b adenosine receptor controls TNF-alpha in macrophages

Presenter: Milka Koupenova

Date: 3/10/09

Title of talk: The role of Adenosine receptors in lipid homeostasis

Presenter: Alexia Eliades

Date: 3/24/09

Title of talk: Oxidative Stress in the platelet lineage

Presenter: Dan Yang, PhD, MD

Date: 4/14/09

Title of talk: Control of Platelet thrombosis

Presenter: Nathan Wigner, PhD

Date: 5/5/09

Title of talk: Mesenchymal Stem Cells Differentiation during tissue regeneration

Presenter: Alexia Eliades

Date: 9/22/09

Title of Talk: “A role for Cyclin E in Megakaryocytic Polyploidization”

Presenter: Larry Luchsinger

Date: 10/27/09

Title of Talk: “Inflammation and matrix production”

Presenter: Shannon Carroll

Date: 11/3/09

Title of Talk: “A2B AR and Bone Healing”

Presenter: Rebecca Zee

Date: 12/8/09

Title of Talk: “Cellular thiol redox environment modulates SIRT1 activity”

Journal Clubs by Trainees and Their Invitees (2006-2007)

Presenter: Cynthia St.Hilaire

Date: March 20, 2006

Title of talk: Vascular smooth muscle adenosine receptor is an inducible receptor (effect of Myb protein)

Presenter: Phyllis Ottaviano

Date: May 22, 2006

Title of talk: Plasma glutathione peroxidase (in the context of oxidative stress and cardiovascular pathology)

Presenter: Clinical Conference at the Department of Cardiology, BMC

Date: June 5, 2006

Title of talk: Case presentation and discussion of pathology

Presenter: Donald J. MacCrann

Date: July 24, 2006

Title of talk: Oxidative stress and Survivin in vascular smooth muscle cells (the role of NOX proteins- in collaboration with Dr. John Keaney)

Presenter: Alexander Vezeridis

Date: September 18, 2006

Title of talk: TBN

Presenter: Cynthia St. Hilaire

Date: November 7, 2006

Title of talk: Generation of A2bAR-GFP transgenic mouse for vascular cell tracing

Presenter: Kristen Park

Date: January 9, 2007

Title of talk: Journal Club – Ion channel regulation of vascular smooth muscle

Presenter: Clinical Conference at the Department of Cardiology, BMC

Date: February 5, 2007

Title of talk: Case presentation and discussion of pathology

Presenter: Cynthia St. Hilaire

Date: February 27, 2007

Title of talk: Practice of talk for thesis committee: Induction of the A2bAR in smooth muscle and significance for

proliferation

Presenter: Alexander Vezeridis

Date: March 13, 2007

Title of talk: Regulation of ApoA-1 and role in biogenesis of HDL: Type III hypelypoproteinemia

Presenter: Donald J. McCrann

Date: April 24, 2007

Title of talk: NOX4 induction of vascular polyploidy

Presenter: Dr. Dan Yang (invited Post Doc)

Date: May 15, 2007

Title of talk: The CXCR4 / SDF-1 axis and recruitment of progenitor cells to injured vessels

Presenter: Cynthia St. Hilaire

Date: June 19, 2007

Title of talk: Transcription factors and other data bases: Application to the study of gene control in the cardiovascular system

Presenter: Kristen Park

Date: July 24, 2007

Title of talk: Review of Methods of efficient Gene Targeting: KO models and application to ion channels

Presenter: Dr. Katya Ravid (PI)

Date: September 10, 2007

Title of talk: tba

Presenter: Michelle Walk and Dr. Nikolaos Papadantonakis

Date: October 23, 2007

Title of talk: Extracellular Matrix – overview; Smooth muscle vs. cardiomyocytes

Presenter: Christopher Sullivan and Dr. Hongjie Chen (invited Post Doc)

Date: November 27, 2007

Title of talk: Vascular gene regulation by SAA; Animal models for the study of vascular pathology

Presenter:  Alexander Vezerides

Date:  December 20, 2007

Title of talk:  Type II hyperlypoprpteinemia: Control of ApoA-1 (Thesis Committee) 

Discussion during one of the journal clubs

Journal Clubs and Seminar Presentations (2004-2005)

Presenter: Greg Cote

Date: May 3, 2004

Title of talk: Neuregulin 1expression and function in the heart

Presenter: Cynthia St.Hilaire

Date: November 11, 2004

Title of talk: Transcriptional regulation of a purine receptor gene in vascular cells (survey of receptor role in vascular function)

Presenter: Phyllis Ottaviano

Date: January 24, 2005

Title of talk: Plasma glutathione peroxidase (in the context of oxidative stress and cardiovascular pathology)

Presenter: Tyler Heibeck

Date: February 7, 2005

Title of talk: Nitrotyrosine-Modified Proteins are associated with oxidative stress: Affinity Capture of Nitrotyrosine-Modified Proteins (Solution and solid phase methods)

Presenter: Donald J. MacCrann

Date: April 12, 2005

Title of talk: Survivin and vascular smooth muscle phenotypes

Presenter: Tyler Heibeck

Date: July 11, 2005

Title of talk: Nitrotyrosine-Modified Proteins and cardiovascular disease

Presenter: Dr. Katya Ravid (program director)

Date: September 20, 2005

Title of talk: Transgenic/knock out models for the study of vascular disease: a survey of recent literature

Presenter: Dr. Marc Lenburg (director of the Microarray Center at BUSM)

Date: November 14, 2005

Title of talk: Genomic and microarray approaches to the study of vascular pathology

Presenter: Dr. Wilson Colucci (Chief, Cardiology, BMC)

Date: December 1, 2005

Title of talk: Cardiovascular Biology: from the lab to the clinic (a case study)