R. J. Rushmore III, Ph.D.

Assistant ProfessorRJR Picture

Phone: 617-638-4109
Email: rushmore@bu.edu
Location: W-702, BUSM

 CV: R. Jarrett Rushmore, Ph.D.– CV

Dr. Rushmore is interested in the capacity of the brain to undergo adaptive or maladaptive change following injury or developmental challenges.  He uses invasive and non-invasive reversible deactivation of cerebral cortical areas to study brain function and to encourage restoration of function after brain damage. He is also interested in the visual circuitry underlying visual neglect. Current studies are focused on examining a major effect of brain damage – cortical spreading depression (CSD). Spreading depression is slow electrical wave that expands the brain damage caused by traumatic or penetrating injury, and Dr. Rushmore is interested both in the  principles of its initiation and propagation as well as discovering ways to attenuate or block the wave and thereby improve function after brain damage.

Dr. Rushmore has received the 2008 CFA Educator of the Year in Graduate Sciences Award and the 2014 CFA Educator of the Year in Pre-clinical Sciences.  He directs the first year medical school Neuroscience module, and is the co-director of the first year medical school Head and Neck Body Structures module. He also teaches in other modules of the first year medical school curriculum. He also teaches and co-directs an Advanced Human Anatomy graduate course (with Kathy Rockland), the Systems Neuroscience, Methods in Neuroscience, and The Cellular Organization of Tissues graduate courses.  He also teaches neuroscience to second year and third year medical students. He is presently the ombudsman for graduate students in the Department of Anatomy and Neurobiology and was the director of the Department graduate programs from 2008-2013.

 

Selected Recent Publications

Amaral AC, Jakovcevski M, McGaughy JA, Calderwood SK, Mokler DJ, Rushmore RJ, Galler JR, Akbarian SA, Rosene DL. (2015) Prenatal protein malnutrition decreases KCNJ3 and 2DG activity in rat prefrontal cortex. Neuroscience. 286:79-86.

McGaughy JA, Amaral AC, Rushmore RJ, Mokler DJ, Morgane PJ, Rosene DL, Galler JR. (2014) Prenatal malnutrition leads to deficits in attentional set shifting and decreases metabolic activity in prefrontal subregions that control executive function.  Dev Neurosci. 36(6):532-41.

Fried PJ, Rushmore RJ,, Moss MB, Valero-Cabré A, Pascual-Leone A.  (2014)  Causal evidence supporting functional dissociation of verbal and spatial working memory in the human dorsolateral prefrontal cortex.  European Journal of Neuroscience 39:1973-81.

Wagner T, Eden U, Rushmore J, Russo CJ, Dipetro L, Fregni F, Simon S, Rotman S, Pitskel NB, Ramos-Estebanez C, Pascual-Leone A, Grodzinsky AJ, Zahn M, Valero-Cabre A.  (2014) Impact of brain tissue filtering on neurostimulation fields: a modeling study.  Neuroimage 85:1048-57.

Rushmore RJ, Desimone C, Valero-Cabre A (2013) Multiple sessions of transcranial direct current stimulation to the intact hemisphere restores visual function after unilateral brain damage.  European Journal of Neuroscience 38:3799-807.

Afifi LM, Rushmore RJ, Valero-Cabre A. (2013)  Benefits of multiple sessions of repetitive transcranial magnetic stimulation for an effective rehabilitation of visuo-spatial function.  European Journal of Neuroscience 37(3):441-54.

Fried P, Elkin-Frankston S, Rushmore RJ, Hilgetag CC, Valero-Cabre A. (2011) Characterization of visual percepts elicited by noninvasive stimulation of the human posterior parietal cortex.  

Elkin-Frankston S, Fried P, Rushmore RJ, Valero-Cabre A (2011) From Qualia to Quantia: A System to Document and Quantify Phosphene Percepts Elicited by Non-Invasive Neurostimulation of the Human Occipital Cortex.  Journal of Neuroscience Methods 198:149-57.

Rushmore RJ, Payne BR, Valero-Cabre A (2010)  Recovery of function following unilateral damage to visuoparietal cortex.  Experimental Brain Research. 203(4):693-700.

MacNeil MA, Purrier S, Rushmore RJ. (2009) The composition of the inner nuclear layer of the cat retina.  Visual Neuroscience.  26(4):365-74.

Rushmore RJ, Rigolo LR, Kopacz A, Afifi L, Valero-Cabre A and Payne BR (2008)  Age-dependent sparing of visual acuity following bilateral lesions of primary visual cortex.  Behavioral Neuroscience 122:1274-83.

Valero-Cabre A, Pascual-Leone A and RJ Rushmore (2008)  Cumulative sessions of repetitive transcranial magnetic stimulation (rTMS) builds up facilitation to further TMS-mediated behavioral disruptions.  Eur J Neurosci 27: 765-74.

Schweid L, Rushmore RJ and A Valero-Cabre (2008)   Cathodal transcranial direct current stimulation (tDCS) on posterior parietal cortex disrupts visuo-spatial processing in the contralateral visual field.  Exp Brain Res 27:765-774.

Rushmore RJ, Valero-Cabre A, Lomber SG, Hilgetag CC and Payne BR. (2006) Functional circuitry underlying neglect and its reversal. Brain 129:1803-1821.

Valero-Cabre A, Rushmore RJ, Payne B. (2006)  Low frequency repetitive transcranial magnetic stimulation on the posterior parietal cortex induces transient contralateral visuo-spatial neglect-like syndrome.  Exp Brain Res. 172:14-21.

Rushmore RJ, Payne BR, Lomber SG. (2005) Functional impact of primary visual cortex deactivation on subcortical target structures in the thalamus and midbrain. Journal of Comparative Neurology 488:414-426.

Payne, B.R. and Rushmore, R.J. Functional circuitry underlying natural and interventional cancellation of visual neglect. Exp. Brain Res., 2004, 154:127-53.