Douglas Rosene, Ph.D.


Phone: 617-638-4061
Fax: 617-638-4922
Location: W-701, BUSM

Dr. Rosene received his B.A. from Stanford University and his Ph.D. from the University of Rochester in Neurobiology and Psychology in 1975 . He completed a three-year postdoc at Harvard Medical School in Neuroanatomy before assuming a faculty position in the Department of Anatomy and Neurobiology at Boston University School of Medicine. He is recognized as one of the world’s experts on the anatomy of the temporal lobe limbic system and has published extensively in this area.

Dr. Rosene is Principal Investigator of a long-standing NIH Program Project to study the neural bases of cognitive decline in the aged monkey and is co-principal investigator on several other NIH grants to study various aspects of aging and age-related disease in primate models. He is co-director for the Laboratory of Cognitive Neurobiology with Dr. Mark Moss.

Dr, Rosene is Course Manager for the Medical Neuroscience course and is co-director for several advanced courses in the neurosciences including the Neurobiology of Aging and Neurobiology of Learning and Memory. In addition, Dr. Rosene has been the recipient of several teaching awards including the Stanley Robbins Award for teaching, the most prestigious award for teaching at the Medical School.

Recent Publications

Chang YM, Rosene DL, Killiany RJ, Mangiamele LA, Luebke JI. 2004 Increased Action Potential Firing Rates of Layer 2/3 Pyramidal Cells in the Prefrontal Cortex are Significantly Related to Cognitive Performance in Aged Monkeys. Cereb Cortex, in press.

Peters A, Rosene DL 2003 In aging, is it gray or white? J Comp Neurol. 462:139-43

O’Brien, S.E. Rosene, D.L., and Luebke, J.J. 2003 GABAa receptor-mediated neurotransmission in the dentate gyrus of the rhesus monkey: A comparison with the rat. Synapse. 49:287-9.

McDannold, N., Moss, M.B., Killiany, R., Rosene, D.L., King, R.L, Jolesz, F.A. and Hynynen, K. 2003 MRI-guided focused ultrasound surgery in the brain: Tests in a primate model. Magn. Reson. Med., 49:1188-1191.

Moore, TL, Killiany, RJ, Herndon, JG, Rosene, DL and Moss, MB. 2003 Impairment in asbtraction and set shifting in aged Rhesus monkeys. Neurobiology of Aging, 24: 125-134.

Blatt, G.J., Pandya, D.N. and Rosene, D.L. 2003 Parcellation of cortical afferents to three distinct sectors in the parahippocampal gyrus of the rhesus monkey: and anatomical and neurophysiological study. J. Comp. Neurol. , 466:161-79.