{"id":609,"date":"2009-06-03T13:54:47","date_gmt":"2009-06-03T17:54:47","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/?page_id=609"},"modified":"2023-06-14T11:34:19","modified_gmt":"2023-06-14T15:34:19","slug":"joseph-p-mizgerd-scd","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/people\/faculty\/joseph-p-mizgerd-scd\/","title":{"rendered":"Joseph P. Mizgerd, Sc.D."},"content":{"rendered":"

Professor of Medicine and Virology, Immunology & Microbiology
\nDirector, Pulmonary Center
\n\"Mizgerd\"<\/a>
\n72 East Concord Street
\nOffice: R-3; 617-358-1186
\nLab: R224; 617-358-1236
\njmizgerd@bu.edu<\/a><\/p>\n

B.A.\u00a0 Amherst College
\nSc.D.\u00a0 Harvard School of Public Health<\/p>\n

See BU Profile<\/a> for additional information and publications<\/p>\n

Our work focuses on immunology in the lung and its influence on acute lower respiratory tract infections.\u00a0 Our research is illuminating the regulation and function of innate and adaptive immune cells and signals in the lung, and how variations in these parameters determine pneumonia susceptibility and outcome.\u00a0 Lung defense consists of immune resistance (the ability to eliminate microbes) and tissue resilience (the ability to prevent or withstand injurious stimuli from infection and inflammation). Both activities are accomplished by the coordinated activities of diverse cell types within the lung, involving some that are constitutively present (including diverse types of epithelial cells, macrophages, lymphocytes, and more) as well as others newly recruited to the infected tissue (including neutrophils plus additional myeloid or lymphoid cells).\u00a0 Effective and productive communication amongst these cells can efficiently destroy microbes without damaging the lung, maintaining respiratory health.\u00a0 Dysregulation of these pathways instead promotes infection (e.g., pneumonia), injury (e.g., the acute respiratory distress syndrome), and other pulmonary diseases.\u00a0 Elucidating factors that differentiate lung infection resistance and susceptibility will enable new approaches to preventing and treating pneumonia.<\/p>\n","protected":false},"excerpt":{"rendered":"

Professor of Medicine and Virology, Immunology & Microbiology Director, Pulmonary Center 72 East Concord Street Office: R-3; 617-358-1186 Lab: R224; 617-358-1236 jmizgerd@bu.edu B.A.\u00a0 Amherst College Sc.D.\u00a0 Harvard School of Public Health See BU Profile for additional information and publications Our work focuses on immunology in the lung and its influence on acute lower respiratory tract […]<\/p>\n","protected":false},"author":929,"featured_media":0,"parent":3313,"menu_order":23,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/wp-json\/wp\/v2\/pages\/609"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/wp-json\/wp\/v2\/users\/929"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/wp-json\/wp\/v2\/comments?post=609"}],"version-history":[{"count":14,"href":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/wp-json\/wp\/v2\/pages\/609\/revisions"}],"predecessor-version":[{"id":5604,"href":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/wp-json\/wp\/v2\/pages\/609\/revisions\/5604"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/wp-json\/wp\/v2\/pages\/3313"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/virol-immunol-microbio\/wp-json\/wp\/v2\/media?parent=609"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}