{"id":17036,"date":"2021-11-01T20:15:31","date_gmt":"2021-11-02T00:15:31","guid":{"rendered":"http:\/\/www.bumc.bu.edu\/ppb\/?post_type=profile&#038;p=17036"},"modified":"2022-09-12T12:40:28","modified_gmt":"2022-09-12T16:40:28","slug":"ryan-logan-phd","status":"publish","type":"profile","link":"https:\/\/www.bumc.bu.edu\/ppb\/profile\/ryan-logan-phd\/","title":{"rendered":"Ryan Logan, PhD"},"content":{"rendered":"<h3><span style=\"color: #333333;\"><strong>Director and Principal Investigator, Laboratory of Sleep, Rhythms, and Addiction<\/strong><\/span><\/h3>\n<h3>Research Interests<\/h3>\n<p>Dr. Logan\u2019s research aims to understand how sleep and circadian rhythms contribute to the vulnerability of substance use disorders. His work integrates tools across genetics, molecular biology, and neuroscience to examine the cellular and molecular mechanisms in the brain involved in 1) the development of drug dependence, craving and relapse and 2) to understand the impact of sleep and circadian rhythm disruption on reward-related and motivated behaviors, to ultimately, 3) identify novel molecular targets to develop therapeutics and interventions for addiction. Dr. Logan\u2019s laboratory uses translational approaches from humans to animals to examine the relationship between sleep, circadian rhythms, and addiction.<\/p>\n<p>Dr. Logan is recognized as a leader in the field of circadian rhythms and addiction research, a largely understudied area of research with high translational value and clinical impact. His research program offers several unique factors that distinguishes his laboratory from others in the field. First, by examining the molecular alterations related to psychiatric disorders in the human postmortem brain, his work is able to identify the pathologies associated with substance use disorders in humans to then target and manipulate related pathways using animal models to uncover mechanisms of addiction. Second, by leveraging genetically diverse mouse populations and computational tools, his work uncovers the genetic and molecular mechanisms that regulate sleep and circadian rhythms, involved in substance use disorders. Third, by using both forward and reverse translational approaches in humans and animals, his work identifies important molecular factors that can be targeted in the development of therapeutics to treat substance use disorders and comorbid mood disorders.<\/p>\n<h3><a href=\"https:\/\/sites.bu.edu\/loganlab\/\"><span style=\"color: #3366ff;\">Lab Page<\/span><\/a><\/h3>\n<h3><span style=\"color: #3366ff;\"><a href=\"https:\/\/profiles.bu.edu\/Ryan.Logan\" style=\"color: #3366ff;\">Publications<\/a><\/span><\/h3>\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h3 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">Recent News<\/h3><div class=\"bu_collapsible_section\" style=\"display: none;\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"cpVtVgi6t4\"><p><a href=\"https:\/\/nextpittsburgh.com\/latest-news\/as-a-new-school-year-begins-parents-and-researchers-call-for-later-school-start-times\/\">As a new academic year begins, parents and researchers call for later high school start times<\/a><\/p><\/blockquote>\n<p><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;As a new academic year begins, parents and researchers call for later high school start times&#8221; &#8212; NEXTpittsburgh\" src=\"https:\/\/nextpittsburgh.com\/latest-news\/as-a-new-school-year-begins-parents-and-researchers-call-for-later-school-start-times\/embed\/#?secret=cpVtVgi6t4\" data-secret=\"cpVtVgi6t4\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>https:\/\/www.news-medical.net\/news\/20210810\/Study-finds-altered-brain-gene-expression-patterns-in-people-with-opioid-use-disorder.aspx<\/p>\n<p>https:\/\/www.elsevier.com\/about\/press-releases\/research-and-journals\/brain-gene-expression-patterns-altered-by-chronic-opioid-use2https:\/\/www.biologicalpsychiatryjournal.com\/article\/S0006-3223(21)01523-7\/fulltext<\/p>\n<p class=\"\"><strong class=\"\">July, 2021<\/strong>\u00a0\u2013 Dr. Madelyn Ray joins the laboratory as a postdoctoral fellow, receiving a fellowship award on the T32<span class=\"\">\u00a0through the Whitaker Cardiovascular Institute; Dr. Stephanie Puig relocates from University of Pittsburgh to Boston University, joining the laboratory as Research Assistant Professor<\/span><\/p>\n<p class=\"\"><strong class=\"\">June, 2021<\/strong>\u00a0\u2013 Ben Williams joins as a laboratory manager, recent alumni of the University of Maine; Navsharan Singh joins the laboratory as Master\u2019s Student<\/p>\n<p class=\"\"><strong class=\"\">April, 2021<\/strong>\u00a0\u2013 Mackenzie Gamble joins as the first graduate student in the laboratory at Boston University<\/p>\n<p class=\"\"><strong class=\"\">March, 2021<\/strong><span>\u00a0\u2013 Dr. Logan joins the Center for Systems Neuroscience at Boston University<\/span><\/p>\n<p class=\"\"><strong class=\"\">February, 2021<\/strong>\u00a0\u2013 newly funded R21 Cutting-Edge Basic Research Award (CEBRA) from NIDA to develop computational tools for analyzing large-volume tissue imaging datasets with collaborators\u00a0Drs. Zach Freyberg and Alan Watson at University of Pittsburgh<\/p>\n<p class=\"\"><strong class=\"\">January, 2021<\/strong><span>\u00a0\u2013 Dr. Logan relocated laboratory from the Department of Psychiatry at the University of Pittsburgh School of Medicine to the Department of Pharmacology and Experimental Therapeutics at Boston University School of Medicine<\/span><\/p>\n<p><\/div>\n<\/div>\n<a href=\"https:\/\/scholar.google.com\/citations?user=BxqdqbUAAAAJ&amp;hl=en\"><\/a><\/p>\n","protected":false},"author":1327,"template":"","_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/profile\/17036"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/users\/1327"}],"version-history":[{"count":11,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/profile\/17036\/revisions"}],"predecessor-version":[{"id":19861,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/profile\/17036\/revisions\/19861"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/media?parent=17036"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}