{"id":19124,"date":"2022-02-25T16:47:05","date_gmt":"2022-02-25T20:47:05","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/ppb\/?p=19124"},"modified":"2022-05-16T19:19:38","modified_gmt":"2022-05-16T23:19:38","slug":"postdoc-fellow-positions-available-in-sepsis-trauma-and-organ-injury-research-at-university-of-maryland-baltimore","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/ppb\/2022\/02\/25\/postdoc-fellow-positions-available-in-sepsis-trauma-and-organ-injury-research-at-university-of-maryland-baltimore\/","title":{"rendered":"Postdoc fellow positions available in Sepsis, Trauma, and Organ Injury research at University of Maryland, Baltimore"},"content":{"rendered":"<p style=\"text-align: center;\"><strong>Postdoctoral Fellow Positions<\/strong><\/p>\n<p><strong>Location:<\/strong><br \/>\nCenter for Shock, Trauma and Anesthesiology Research (STAR Center)<br \/>\nR Adams Cowley Shock Trauma Center<br \/>\nUniversity of Maryland School of Medicine<br \/>\nBaltimore, MD<\/p>\n<p><strong>Projects:<\/strong><br \/>\nTo study the role of extracellular miRNAs and EVs in regulating innate immunity and inflammatory<br \/>\nresponses in critical illness \u2013 trauma, sepsis, ischemic organ injury.<\/p>\n<p><strong>Funding:<\/strong><br \/>\nNIGMS, NINDS, NHLBI, National Science Foundation, US Air Force<\/p>\n<p><strong>Position Description:<\/strong><br \/>\nThe STAR Center is a world-class, multi-disciplinary research and educational center focusing on critical<br \/>\ncare and organ support, resuscitation, surgical outcomes, patient safety and injury prevention. We are<br \/>\ncurrently seeking highly trained and motivated postdoctoral fellows to join our Translational Research<br \/>\nProgram to investigates the role of extracellular vesicles (EVs) and microRNA-mediated innate immune<br \/>\nsignaling in 1) sepsis-associated brain inflammation and cognitive dysfunction, 2) acute lung injury, 3)<br \/>\ncoagulopathy in sepsis and trauma, and 4) cardiac ischemia injury. These translational projects involve<br \/>\nboth humans and animals.<\/p>\n<p><strong>A list of recent publications:<\/strong><br \/>\n1. Chen C, et al. Role of extracellular RNA and TLR3-Trif signaling in myocardial ischemia-reperfusion injury. J Am<br \/>\nHeart Assoc. 2014 Jan 3; 3(1): e000683. PMID: 24390148<br \/>\n2. Chen F, et al. Targeting Toll-Like receptors in sepsis &#8211; From bench to clinical trials (Review). Antioxid Redox<br \/>\nSignal. 2021; PMID: 33588628<br \/>\n3. Xu J, et al. Circulating plasma extracellular vesicles from septic mice induce inflammation via microRNA- and<br \/>\nTLR7-dependent mechanisms. J Immunol. 2018; 201: 3392-3400. PMID: 30355788<br \/>\n4. Jeyaram A, et al. Enhanced loading of functional miRNA cargo via pH-gradient modification of extracellular<br \/>\nvesicles. Molecular Therapy 2020; 28(3):975-985. PMID:31911034<br \/>\n5. Williams B, et al. Toll-like receptor 2 and 7 mediate coagulation activation and coagulopathy in murine sepsis. J<br \/>\nThromb Haemost. 2019; 17:1683-1693. PMID: 31211901<br \/>\n6. Kronstadt SM, et al. Therapeutic Potential of Extracellular Vesicles for Sepsis Treatment (Review). Adv Ther<br \/>\n(Weinh). 2021 Jul;4(7) PMID: 34423113<br \/>\n7. Wang S, et al. Role of Extracellular MicroRNA-146a-5p in Host Innate Immunity and Bacterial Sepsis. iScience.<br \/>\n2021 24(12), 103441. PMID: 34877498<br \/>\n8. Zou L, et al. Brain Innate Immune Response via miRNA-TLR7 Sensing in Polymicrobial Sepsis. Brain Behavior<br \/>\nImmunity. Brain Behav Immun. 2021 100, 10-24. PMID: 34808293.<\/p>\n<p>The candidates with PhD or MD degree in molecular\/cell biology, physiology, pharmacology, neuroscience,<br \/>\nand immunology are encouraged to apply. The ideal candidate should have excellent written and oral<br \/>\ncommunication skills and independent ability to design and execute experiments.<\/p>\n<p>Interested candidates should send the following materials to <strong>Ms. Danielle Hill<\/strong> (<a href=\"mailto:dhill3@som.umaryland.edu\">dhill3@som.umaryland.edu<\/a>):<br \/>\n1) Cover letter with a brief description of your research interest and career goal<br \/>\n2) CV<br \/>\n3) Contact information of 3 references<\/p>\n<p><em>The University of Maryland, Baltimore is an Equal Opportunity\/ Affirmative Action Employer. Minorities, women, <\/em><em>individuals with disabilities, and protected veterans are encouraged to apply.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Postdoctoral Fellow Positions Location: Center for Shock, Trauma and Anesthesiology Research (STAR Center) R Adams Cowley Shock Trauma Center University of Maryland School of Medicine Baltimore, MD Projects: To study the role of extracellular miRNAs and EVs in regulating innate immunity and inflammatory responses in critical illness \u2013 trauma, sepsis, ischemic organ injury. Funding: NIGMS, [&hellip;]<\/p>\n","protected":false},"author":20397,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/posts\/19124"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/users\/20397"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/comments?post=19124"}],"version-history":[{"count":1,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/posts\/19124\/revisions"}],"predecessor-version":[{"id":19127,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/posts\/19124\/revisions\/19127"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/media?parent=19124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/categories?post=19124"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/tags?post=19124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}