{"id":60,"date":"2008-05-27T14:09:29","date_gmt":"2008-05-27T18:09:29","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/ppb\/curriculum\/introduction-to-medical-pharmacology\/"},"modified":"2023-01-24T15:42:02","modified_gmt":"2023-01-24T20:42:02","slug":"imp","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/ppb\/education\/pharmacology\/training-program\/academics\/courses\/imp\/","title":{"rendered":"Introduction to Medical Pharmacology"},"content":{"rendered":"<ul class=\"noindent\">\n<li><a href=\"#prereqs\">Prerequisites<\/a><\/li>\n<li><a href=\"#objectives\">Course Objectives, Assignments, Grading<\/a><\/li>\n<li><a href=\"#schedule\">Lecture Schedule<\/a><\/li>\n<li><a href=\"#lecturers\">Lecturers<\/a><\/li>\n<\/ul>\n<hr \/>\n<p><a name=\"prereqs\"><\/a><\/p>\n<p>Introduction to Medical Pharmacology, GMS PM 730<\/p>\n<p>Prereq: Premedical curriculum.<\/p>\n<p><a href=\"https:\/\/www.bumc.bu.edu\/ppb\/people\/faculty\/faculty-profiles\/cottone\/\">Cottone<\/a> and <a href=\"https:\/\/www.bumc.bu.edu\/ppb\/people\/faculty\/faculty-profiles\/vidhya-kumaresan\/\">Kumaresan<\/a> staff. 4 cr, 2nd sem.<\/p>\n<hr \/>\n<h3><strong><a name=\"objectives\"><\/a><\/strong><\/h3>\n<h3><strong> <\/strong><strong>Objectives, Assignments, and Grading<\/strong><\/h3>\n<p><strong>Course Objectives:<\/strong> This course is designed to introduce medical pharmacology to students who are pursuing degrees in the Medical Sciences. Topics will include the basic principles of pharmacology and several major classes of therapeutic agents, with attention to their mechanisms of action. Issues of current and future concern in medical pharmacology will be addressed including the sources of information about pharmacologic agents, the ethics of human experimentation, the drug development process and its costs, problems of drug abuse, and new biotechnological approaches to drug design.<\/p>\n<p><strong>Reading Assignments:<\/strong> The text for this course is Levine\u2019s Pharmacology: Drug Actions and Reactions, 7th ed., Carol T. Walsh and Rochelle Schwartz-Bloom, Taylor &amp; Francis, 2005. The book is available through e-Book resources in the library. The reading assignments for each class are indicated on the lecture schedule. Other reading assignments may be distributed in class or on the BlackBoard site.<\/p>\n<p><strong>Course Grade:<\/strong>\u00a0The course grade will be determined from the grades for the examinations (40% for Exam 1; 30% each for Exams 2 and 3). This final course score will be converted to a letter grade approximately as follows:<\/p>\n<p>Final Course Score: Letter Grade<\/p>\n<p>93 and above:\u00a0 A<\/p>\n<p>84-92: \u00a0 A-<\/p>\n<p>78-83: \u00a0 B+<\/p>\n<p>70-77: \u00a0 B<\/p>\n<p>62-69: \u00a0 B-<\/p>\n<p>53-61: \u00a0 C+<\/p>\n<p>45-52: \u00a0 C<\/p>\n<p><strong>Course Managers:<\/strong> Pietro Cottone, Ph.D. 72 Est Concord Street, 617-358-1950, <a href=\"cottone@bu.edu\">cottone@bu.edu<\/a>; Vidhya Kumaresan, Ph.D. 72 Est Concord Street, 617-358-9580, <a href=\"mailto:vidhya@bu.edu\">vidhya@bu.edu<\/a><\/p>\n<hr \/>\n<h3><a name=\"schedule\"><\/a><\/h3>\n<h3>Lecture Schedule<\/h3>\n<p>Semester 2, 2022-2023<br \/>\nMondays and Wednesdays, 10:00-11:50 AM<br \/>\nLectures in L-110*<\/p>\n<p>*Changes in regular classroom may occur<\/p>\n<p>&nbsp;<\/p>\n<p>Mon, Jan 23<sup>rd<\/sup> &#8211; Introduction and Development of Pharmacology (Dr. Cottone and Dr. Walsh)<\/p>\n<p>Sources of Information About Drugs (Dr. Walsh)<\/p>\n<p>Wed, Jan 25<sup>th<\/sup> &#8211; Mechanisms of Drug Action (Dr. Cottone)<\/p>\n<p>Mon, Jan 30<sup>th<\/sup> &#8211; Principles of Pharmacodynamics &#8211; Part 1 (Dr. Cottone)<\/p>\n<p>Wed, Feb 1<sup>st<\/sup> &#8211; Principles of Pharmacodynamics &#8211; Part 2\u00a0 (Dr. Cottone)<\/p>\n<p>Mon, Feb 6<sup>th<\/sup> &#8211; Drug Transport and Absorption (Dr. Walsh)<\/p>\n<p>Wed, Feb 8<sup>th<\/sup>&#8211; Drug Distribution and Elimination (Dr. Walsh)<\/p>\n<p>Mon, Feb 13<sup>th<\/sup> &#8211; Time-Concentration Relationships (Dr. Walsh)<\/p>\n<p>Wed, Feb 15<sup>th<\/sup> &#8211; Biopharmaceutics, Drug Delivery Systems and Generic vs. Proprietary Drugs (Dr. Walsh)<\/p>\n<p>Mon, Feb 20<sup>th<\/sup> &#8211; NO CLASS (President&#8217;s Day)<\/p>\n<p>Wed Feb 22<sup>nd<\/sup> &#8211; Pharmacology of the Autonomic Nervous System\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (Dr. Kumaresan)<\/p>\n<p>Mon Feb 27<sup>th<\/sup> &#8211; Population Pharmacology 1: Phenotype and Genotype (Dr. Fisher)<\/p>\n<p>Wed, Mar 1<sup>st<\/sup> &#8211; EXAM I, 10:00am-11:30am<\/p>\n<p>Mar 4<sup>th<\/sup> -12<sup>th<\/sup> &#8211; SPRING BREAK<\/p>\n<p>Mon, Mar 13<sup>th<\/sup> &#8211; Pharmacology of Hypertension (Dr. Wainford)<\/p>\n<p>Wed, Mar 15<sup>th<\/sup> &#8211; Population Pharmacology 2: Adherence, Interactions, the Allergic Response and Mechanisms of Tolerance\u00a0\u00a0 (Dr. Walsh)<\/p>\n<p>Mon, Mar 20<sup>th<\/sup> &#8211; Pharmacology of Pain and Inflammation (Dr. Zachariou)<\/p>\n<p>Wed, Mar 22<sup>nd<\/sup> &#8211; Dopamine and Serotonin: Anti-Depressants, Anti-Parkinson&#8217;s Agents, and Anti-Psychotics (Dr. Cottone)<\/p>\n<p>Mon, Mar 27<sup>th<\/sup> &#8211; Development and Pharmacology of Antianxiety and Antiepileptic Agents (Dr. Russek)<\/p>\n<p>Wed, Mar 29<sup>th<\/sup> &#8211; Pharmacology of Substance Abuse Pharmacology of CNS Stimulants (Dr. Cottone and Dr. Sabino)<\/p>\n<p>Mon, Apr 3<sup>rd<\/sup> &#8211; Pathophysiology of Diabetes and antidiabetic drugs (Dr. Cottone)<\/p>\n<p>Wed, Apr 5<sup>th<\/sup> &#8211; EXAM II, 10:00am-11:30am<\/p>\n<p>Mon, Apr 10<sup>th<\/sup> &#8211; Principles of Chemotherapy (Dr. Walsh)<\/p>\n<p>Wed, Apr 12<sup>th<\/sup> &#8211; Cancer Chemotherapeutic Agents (Dr. Feng)<\/p>\n<p>Mon, Apr 17<sup>th<\/sup> &#8211; NO CLASS (Patriot&#8217;s Day)<\/p>\n<p>Wed, Apr 19<sup>th<\/sup> &#8211; Principles of Toxicology\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0\u00a0\u00a0 (Dr. Walsh)<\/p>\n<p>Mon , Apr 24<sup>th<\/sup> &#8211; Incidence of Poisonings Treatment of Poisonings (Dr. Walsh)<\/p>\n<p>Therapeutics Development for Alzheimer&#8217;s Disease: Opportunities and Challenges (Dr. Farb)<\/p>\n<p>Wed, Apr 26<sup>th<\/sup> &#8211; Advances in the Development of Biopharmaceuticals (Dr. Nocula-Lugowska)<\/p>\n<p>Mon, May 1<sup>st<\/sup> &#8211; Cytokines as Therapeutic Drug Targets (Dr. Martin)<\/p>\n<p>Wed, May 3<sup>rd<\/sup> &#8211; Vaccines and Targeted Anti-Cancer Agents (Dr. Feng)<\/p>\n<p>Mon,\u00a0 May\u00a0 8<sup>th<\/sup> &#8211; EXAM III, 10:00am-11:30am<\/p>\n<hr \/>\n<h3><a name=\"lecturers\"><\/a><\/h3>\n<h3>Lecturers<\/h3>\n<p>COTTONE, Pietro, Ph.D., Associate Professor of Pharmacology and Psychiatry. Research interest: Neurobiology of addictions including eating disorders. R-618, Ext. 8-1950, <a href=\"mailto:cottone@bu.edu\">cottone@bu.edu<\/a>.<\/p>\n<p>&nbsp;<\/p>\n<p>FARB, David H, Ph.D. Professor of Pharmacology. Research Interests: Identification of pharmacological treatments for disorders of learning and memory function. L-603, Ext. 8-1900, <a href=\"mailto:dfarb@bu.edu\">dfarb@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>FENG, Hui, M.D., Ph.D. Associate Professor of Pharmacology and Medicine. Research Interests: identifying novel genes and pathways that are essential for tumor initiation and progression. K-712A Ext. 8-4171, <a href=\"mailto:huifeng@bu.edu\">huifeng@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>FISHER, Shannon, M.D., Ph.D. Associate Professor of Pharmacology and Medicine. Research Interests: Use of the zebrafish as a model organism for the study of skeletal dysplasias. W-607D Ext. 8-4302, <a href=\"mailto:shanfish@bu.edu\">shanfish@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>KUMARESAN, Vidhya, Ph.D., Research Assistant Professor, Research Interests: neuronal activity-dependent plasticity and its relevance for brain disorders. L-616, <a href=\"mailto:vidhya@bu.edu\">vidhya@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>MARTIN, David, Executive Director, Pfizer. Research Interests: Rheumatology. <a href=\"mailto:david.a.martin@pfizer.com\">david.a.martin@pfizer.com<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>NOCULA-LUGOWSKA, Malgorzata, Ph.D. Senior Principal Scientist, Research Interests: antibody and protein engineer with industry experience in the design and discovery of monoclonal and multispecific antibodies. <a href=\"mailto:malgorzata.nocula-lugowska@pfizer.com\">malgorzata.nocula-lugowska@pfizer.com<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>RUSSEK, Shelley, Ph.D., Professor of Pharmacology and Biology.\u00a0 Research interests:\u00a0 Regulation of genes for CNS receptors. \u00a0L-606, Ext. 8-4319, <a href=\"mailto:srussek@bu.edu\">srussek@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>SABINO, Valentina, Ph.D., Associate Professor of Pharmacology and Psychiatry. Research interests: Neurobiology of addiction and stress-related disorders. R-612, Ext. 8-1311, <a href=\"mailto:vsabino@bu.edu\">vsabino@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>WAINFORD, Richard, Ph.D., Associate Professor of Pharmacology and Medicine.\u00a0 Research interests: CNS regulation of blood pressure and renal function.\u00a0 W-607, Ext. 4-8238, <a href=\"mailto:rwainf@bu.edu\">rwainf@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>WALSH, Carol T., Ph.D., Professor of Pharmacology.<\/p>\n<p>Research interests:\u00a0 Pharmacokinetics, gastrointestinal pharmacology, metal toxicology.\u00a0 R-610, Ext. 8-1320, <a href=\"mailto:ctwalsh@bu.edu\">ctwalsh@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>ZACHARIOU, Venetia, Ph.D., Chair and Professor of Pharmacology.<\/p>\n<p>Research interests: Signal transduction, epigenetics, G proteins, chronic pain, addiction. <a href=\"mailto:vzachari@bu.edu\">vzachari@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"mailto:vzachari@bu.edu\"><\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>STAFF<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>Holman, Licia, Academic Manager, Department of Pharmacology &amp; Experimental Therapeutics. L-603, Ext. 8-9564, <a href=\"mailto:pharm2@bu.edu\">pharm2@bu.edu<\/a><\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n","protected":false},"excerpt":{"rendered":"<p>Prerequisites Course Objectives, Assignments, Grading Lecture Schedule Lecturers Introduction to Medical Pharmacology, GMS PM 730 Prereq: Premedical curriculum. Cottone and Kumaresan staff. 4 cr, 2nd sem. Objectives, Assignments, and Grading Course Objectives: This course is designed to introduce medical pharmacology to students who are pursuing degrees in the Medical Sciences. Topics will include the basic [&hellip;]<\/p>\n","protected":false},"author":947,"featured_media":0,"parent":61,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"page-templates\/no-sidebars.php","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/pages\/60"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/users\/947"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/comments?post=60"}],"version-history":[{"count":37,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/pages\/60\/revisions"}],"predecessor-version":[{"id":20231,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/pages\/60\/revisions\/20231"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/pages\/61"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/media?parent=60"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}