![\"LAD_logo\"](\"\/ppb\/files\/2010\/05\/LAD_logo2.jpg\"){kind=logo}
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Open positions in LAD may be available year round. Please contact Drs. Cottone (<\/span>cottone@bu.edu<\/a>) and Sabino (<\/span>vsabino@bu.edu<\/a>) for information.<\/span><\/strong><\/p>\n The major interest of the Laboratory of Addictive Disorders (LAD)<\/em> is to unravel the neurobiological mechanisms of motivated behaviors. Research is focused on assessing the effects of exposure to rewards -including alcohol, drugs and palatable food- on behavior and brain function. The laboratory uses environmental and genetic animal models of disease, coupled to molecular biological and biochemical techniques.<\/p>\n Mission of LAD:<\/em><\/strong><\/span> Dr. Sabino\u2019s primary interests are to understand the neurobiological substrates of addiction to drugs of abuse -especially alcohol- as well as stress-related disorders and depression. An integrative behavioral, pharmacological and molecular approach is utilized to achieve the goals. The laboratory is working toward the development of new therapeutic agents to treat these psychiatric diseases.\u00a0 Current projects include exploring the role of the sigma receptor system in alcohol addiction and depression, and the investigation of the role of hypothalamic and extrahypothalamic neuropeptide systems in stress and anxiety.<\/p>\n Dr. Cottone\u2019s research interests focus on the neurobiology of motivated behaviors and stress-related disorders. The major goal of Dr. Cottone\u2019s research is identifying the biological bases of and potential treatments for eating disorders and obesity. Current projects evaluate the role of the corticotropin-releasing factor (CRF) and the endocannabinoid systems in compulsive eating and hedonic food intake. Dr. Cottone\u2019s studies are carried out on environmental and genetic animal models, using behavioral, biochemical, and molecular approaches.<\/p>\n Dr. Cottone and Dr. Sabino are Training Faculty in the following programs: \n\t Associate Professor of Pharmacology, Physiology & Biophysics and Psychiatry<\/p>\t<\/a>\n\n\t\n<\/li>\n\t\t\t\t\t\n Professor of Pharmacology, Physiology & Biophysics and Psychiatry<\/p>\t<\/a>\n\n\t\n<\/li>\n\t\t\t<\/ul>\n<\/p>\n <\/div>\n<\/div>\n\n Dr. Valentina Sabino, Email:<\/span> vsabino@bu.edu<\/a>.<\/p>\n Dr. Pietro Cottone, Email:<\/span> cottone@bu.edu<\/a>.<\/p>\n <\/div>\n<\/div>\n\n Minnig MA, Park T, Echeveste Sanchez M, Cottone P, Sabino V. Viral-Mediated Knockdown of Nucleus Accumbens Shell PAC1 Receptor Promotes Excessive Alcohol Drinking in Alcohol-Preferring Rats. Front Behav Neurosci. 2021 Dec 3;15:787362.<\/p>\n Quadir SG, Tanino SM, Sami YN, Minnig MA, Iyer MR, Rice KC, Cottone P, Sabino V. Antagonism of Sigma-1 receptor blocks heavy alcohol drinking and associated hyperalgesia in male mice. Alcohol Clin Exp Res. 2021 Jul;45(7):1398-1407. doi: 10.1111\/acer.14635. Epub 2021 Jul 5. PMID: 34060104<\/p>\n Ferragud A, Velazquez-Sanchez C, Minnig MA, Sabino V, Cottone P. Pituitary adenylate cyclase-activating polypeptide (PACAP) modulates dependence-induced alcohol drinking and anxiety-like behavior in male rats. Neuropsychopharmacology. 2021 Feb;46(3):509-518. doi: 10.1038\/s41386-020-00904-4. Epub 2020 Nov 16. PMID: 33191400<\/p>\n Hicks C, Sabino V, Cottone P. The Alpha-1 Adrenergic Receptor Antagonist Prazosin Reduces Binge-Like Eating in Rats. Nutrients. 2020 May 28;12(6):1569. doi: 10.3390\/nu12061569. PMID: 32481494<\/p>\n Ferragud A, Vel\u00e1zquez-S\u00e1nchez C, Abdullatif AA, Sabino V, Cottone P. Withdrawal from Extended, Intermittent Access to A Highly Palatable Diet Impairs Hippocampal Memory Function and Neurogenesis: Effects of Memantine. Nutrients. 2020 May 23;12(5):1520. doi: 10.3390\/nu12051520. PMID: 32456193<\/p>\n Quadir SG, Rohl CD, Zeabi A, Moore CF, Cottone P, Sabino V. Effect of different standard rodent diets on ethanol intake and associated allodynia in male mice. Alcohol. 2020 Sep;87:17-23. doi: 10.1016\/j.alcohol.2020.04.003. Epub 2020 Apr 21. PMID: 32330590<\/p>\n Seiglie MP, Huang L, Cottone P, Sabino V. Role of the PACAP system of the extended amygdala in the acoustic startle response in rats. Neuropharmacology. 2019 Dec 1;160:107761. doi: 10.1016\/j.neuropharm.2019.107761. Epub 2019 Sep 4. PMID: 31493466<\/p>\n Moore CF, Blasio A, Sabino V, Cottone P. Impulsive choice does not predict binge-like eating in rats. Behav Pharmacol. 2018 Dec;29(8):726-731. doi: 10.1097\/FBP.0000000000000446. PMID: 30325787<\/p>\n Moore CF, Sabino V, Cottone P. Trace Amine Associated Receptor 1 (TAAR1) Modulation of Food Reward. Front Pharmacol. 2018 Feb 27;9:129. doi: 10.3389\/fphar.2018.00129. PMID: 29535626<\/p>\n Moore CF, Sabino V, Koob GF, Cottone P. Neuroscience of Compulsive Eating Behavior. Front Neurosci. 2017 Aug 24;11:469. doi: 10.3389\/fnins.2017.00469. PMID: 28883784<\/p>\n Vel\u00e1zquez-S\u00e1nchez C, Ferragud A, Moore CF, Everitt BJ, Sabino V, Cottone P. Neuropsychopharmacology. To the publication section, we will need two publications added: High Trait Impulsivity Predicts Food Addiction-Like Behavior in the Rat. 2014 Apr 29. doi: 10.1038\/npp.2014.98. [Epub ahead of print] PMID: 24776685 <\/a>.<\/p>\n Baiamonte BA, Valenza M, Roltsch EA, Whitaker AM, Baynes BB, Sabino V, Gilpin NW. Nicotine dependence produces hyperalgesia: role of corticotropin-releasing factor-1 receptors (CRF1Rs) in the central amygdala (CeA). Neuropharmacology. 2014 Feb;77:217-23. doi: 10.1016\/j.neuropharm.2013.09.025. Epub 2013 Oct 6. PMID: 24107576 <\/a><\/p>\n Blasio A, Iemolo A, Sabino V, Petrosino S, Steardo L, Rice KC, Orlando P, Arturo Iannotti F, Di Marzo V, Zorrilla EP, Cottone P. Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdale. Neuropsycholpharmacology<\/em>. 2013 Jun 24. Epub ahead of print<\/a>.<\/p>\n Sabino V, Narayan AR, Zeric T, Steardo L, Cottone P. mTOR activation is required for the anti-alcohol effect of ketamine, but not memantine, in alcohol-preferring rats. Behav Brain Res<\/em>. 2013 Jun 15;247:9-16. PubMed PMID: 23466691; PubMed Central PMCID: PMC3646912<\/a>.<\/p>\n Iemolo A, Blasio A, St Cyr SA, Jiang F, Rice KC, Sabino V, Cottone P. CRF-CRF1<\/sub> Receptor System in the Central And Basolateral Nuclei Of The Amygdala Differentially Mediates Excessive Eating Of Palatable Food. Neuropsychopharmacology<\/em>. 2013 Jun 10;PubMed PMID: 23748225<\/a>.<\/p>\n Dore R, Iemolo A, Smith KL, Wang X, Cottone P, Sabino V. CRF Mediates the Anxiogenic and Anti-Rewarding, But Not the Anorectic Effects of PACAP. Neuropsychopharmacology.2013 May 9;PubMed PMID: 23657440<\/a>.<\/p>\n Dore R, Valenza M, Wang X, Rice KC, Sabino V, Cottone P. The inverse agonist of CB1<\/sub> receptor SR141716 blocks compulsive eating of palatable food. Addict Biol<\/em>. 2013 Apr 16;PubMed PMID: 23587012<\/a>.<\/p>\n Sabino V, Kwak J, Rice KC, Cottone P. Pharmacological characterization of the 20% alcohol intermittent access model in sardinian alcohol-preferring rats: a model of binge-like drinking. Alcohol Clin Exp Res<\/em>. 2013 Apr;37(4):635-43. PubMed PMID: 23126554; PubMed Central PMCID: PMC3567206<\/a>.<\/p>\n Cottone P, Sabino V, Nagy TR, Coscina DV, Levin BE, Zorrilla EP. Centrally administered urocortin 2 decreases gorging on high-fat diet in both diet-induced obesity-prone and -resistant rats. Int J Obes (Lond)<\/em>. 2013 Mar 12;PubMed PMID: 23478425<\/a>.<\/p>\n Cottone P, Iemolo A, Narayan AR, Kwak J, Momaney D, Sabino V. The uncompetitive NMDA receptor antagonists ketamine and memantine preferentially increase the choice for a small, immediate reward in low-impulsive rats. Psychopharmacology (Berl).<\/em> 2013 Mar;226(1):127-38. PubMed PMID: 23104264; PubMed Central PMCID: PMC3572289<\/a>.<\/p>\n Blasio A, Steardo L, Sabino V, Cottone P. Opioid system in the medial prefrontal cortex mediates binge-like eating. Addict Biol. <\/em>2013 Jan 24;PubMed PMID: 23346966; PubMed Central PMCID: PMC3664255<\/p>\n Parylak SL, Cottone P, Sabino V, Rice KC, Zorrilla EP. Effects of CB1 and CRF1 receptor antagonists on binge-like eating in rats with limited access to a sweet fat diet: lack of withdrawal-like responses. Physiol Behav. <\/em>2012 Sep 10;107(2):231-42. PubMed PMID: 22776620. Cottone P, Wang X, Park JW, Valenza M, Blasio A, Kwak J, Iyer MR, Steardo L, Rice KC, Hayashi T, Sabino V. Antagonism of Sigma-1 Receptors Blocks Compulsive-Like Eating Neuropsychopharmacology. <\/em> 2012 Nov; 37(12);2593-604 <\/a>. <\/a>.<\/p>\n Blasio A, Narayan AR, Kaminski BJ, Steardo L, Sabino V, Cottone P. A modified adjusting delay task to assess implusive choice between isocaloric reinforcers in non-deprived male rats: effects of 5-HT2A\/C and 5-HT1A receptor agonists. Psychopharmacology (Berl). <\/em> 2012 Jan; 219(2):377-86.<\/p>\n Fekete EM, Zhao Y, Sz\u00fccs A, Sabino V, Cottone P, Rivier J, Vale WW, Koob GF, Zorrilla EP. Systemic urocotrin 2, but not urocortin 1 or stressin 1-A, suppresses feeding via CRF2 receptors without malaise and stress. Br J Pharmacol.<\/em> 2011 Dec; 164(8):1959-75.<\/p>\n Sabino V, Cottone P, Blasio A, Iyer MR, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP. Activation of\u00a0\u03c3-receptor induces binge-like drinking in Sardinian alcohol-preferring rats. Neuropsychopharmacology. <\/em> 2011 May; 36(6):1207-18. PMC 3079320. <\/a>.<\/p>\n Repunte-Canonigo V, Berton F., Cottone P, Reifel-Miller A, Roberts AJ, Morales M., Francesconi W, Sanna PP. A potential role for adiponectin receptor 2 (AdipoR2) in the regulation of alcohol intake. Brain Res <\/em> 2010 Jun 21; 1339:11-7. PMC2906226. <\/a>.<\/p>\n Repunte-Canonigo V, van der Stap LD, Chen J, Sabino V, Wagner U, Zorrilla EP, Schumann G, Roberts AJ, Sanna PP. Genome-wide gene expression analysis identifies K-ras as a regulator of alcohol intake. Brain Res<\/em>. 2010 Jun 21;1339: 1-10. PMC2925131.<\/a>.<\/p>\n Roberto M, Cruz MT, Gilpin NW, Sabino V, Schweitzer P, Bajo M, Cottone P, Madamba SG, Stouffer DF, Zorrilla EP, Koob GF, Siggins GF, Parson LH. Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release play a key role in alcohol dependence. Biol Psychiatry. <\/em>2010 May 1; 67(9):831-9. PMC2883449. <\/a>.<\/p>\n Cottone P, Sabino V, Roberto M, Bajo M, Pockros L, Frihauf J, Fekete EM, Steardo L, Rice KC, Grigoriadis D, Conti B, Koob GF, Zorrilla EP. CRF system recruitment mediates dark side of compulsive eating. Proc Natl Acad Sci U S A. <\/em>2009 Nov 24;106(47):20016-20. PMC Journal 2785284 Fonareva I, Spangler E, Cannella N, Sabino V, Cottone P, Ciccocioppo R, Zorrilla EP, Ryabinin AE. Increased perioculomotor Urocortin 1 immunoreactivity in genetically selected alcohol preferring rats. Alcohol Clin Exp Res<\/em>. (2009); 33(11):1956-65. PMC 2813693.<\/a>.<\/p>\n Sabino V, Cottone P, Zhao Y, Steardo L, Koob GF, Zorrilla EP. Selective reduction of alcohol drinking in Sardinian alcohol-preferring rats by a sigma-1 receptor antagonist. Psychopharmacol<\/em> 2009; 205(2): 327-335. PMC2748837<\/p>\n Greenwell TN, Funk CK, Cottone P, Richardson HN, Chen SA, Rice KC, Zorrilla EP, Koob GF. Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long-, but not short-access rats. Addiction Biology<\/em> 2009 Apr;14(2):130-43. PMC2748834<\/p>\n Sabino V, Cottone P, Parylak SL, Steardo L, Zorrilla EP. Sigma-1 receptor knockout mice display a depressive-like phenotype. Behav Brain Res<\/em> 2009; 198(2): 472-476. PMC2667953<\/p>\n Sabino V, Cottone P, Zhao Y, Iyer M, Steardo L yr, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP. The sigma receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking. Neuropsychopharmacol<\/em> 2009; 34(6): 1482-93. PMC2669694<\/p>\n Cottone P, Sabino V, Steardo L, Zorrilla EP. Consummatory, anxiety-related and metabolic adaptations in female rats with alternating access to preferred food. Psychoneuroendocrinol<\/em> 2009; 34(1):38-49. PMCID: PMC3224792.<\/p>\n Greenwell TN, Walker BM, Cottone P, Zorrilla EP, Koob GF. The alpha(1) adrenergic receptor antagonist prazosin reduces heroin self-administration in rats with extended access to heroin administration. Pharmacol Biochem Behav<\/em>. 2009; 91(3):295-302. PMC2637926<\/p>\n Cottone P, Sabino V, Steardo S, Zorrilla EP. Intermittent preferred food access reduces the reinforcing efficacy of chow in rats. Am J Physiol Regul Integr Comp Physiol<\/em> 2008; 295(4):R1066-76. PMC2576087<\/p>\n Cottone P, Sabino V, Steardo L, Zorrilla EP. Opioid-dependent anticipatory negative contrast and binge-like eating in rats with limited access to highly preferred food. Neuropsychopharmacol<\/em> 2008; 33(3):524-35. PMC Journal – In Process<\/p>\n George O, Ghozland S, Azar MR, Cottone P, Zorrilla EP, Parsons LH, O\u2019Dell LE, Richardson HN, Koob GF. CRF-CRF1 system activation mediates withdrawal-induced anxiety-like behavior and increases in nicotine self-administration in nicotine dependent rats. Proc Natl Acad Sci<\/em> 2007; 104(43):17198-203. PMC2040467<\/p>\n Cottone P, Sabino V, Nagy TR, Rivier JE, Coscina DV, Zorrilla EP. Feeding microstructure in diet-induced obesity susceptible and resistant rats: comparative central effects of urocortin 2. J Physiol 2007; 583(Pt 2):487-504. PMC2277029<\/p>\n Sabino V, Cottone P, Steardo L, Schmidhammer H, Zorrilla EP. 14-methoxymetopon, a highly potent mu opioid agonist, biphasically affects ethanol intake in Sardinian alcohol-preferring rats. Psychopharmacol<\/em> 2007; 192(4):537-46. PMC Journal – In Process<\/p>\n Cottone P, Sabino V, Steardo L, Zorrilla EP. FG 7142 specifically reduces meal size and the rate and regularity of sustained feeding in female rats: evidence that benzodiazepine inverse agonists reduce food palatability. Neuropsychopharmacol<\/em> 2007; 32(5):1069-81. PMC Journal – In Process<\/p>\n Sabino V, Cottone P, Koob GF, Steardo L, Lee MJ, Rice KC, Zorrilla EP. Dissociation between opioid and CRF1 antagonist sensitive drinking in Sardinian alcohol-preferring rats. Psychopharmacol<\/em> 2006; 189(2):175-86. PMC Journal – In Process<\/p>\n Publication Search via PubMed<\/a><\/p>\n <\/div>\n<\/div>\n\n Drs. Pietro Cottone and Valentina Sabino become U.S. citizens. Dr. Cottone Records Album\/Shares Perspective in the Boston Globe and BU Today.<\/a><\/p>\n Cassie Moore receives Ruth L Kirschstein NRSA Predoctoral Fellowship from NIDA.<\/a><\/p>\n Neurobiology of Compulsive Eating <\/a>Presentation at The Royal Society’s “Of mice and mental health: facilitating dialogue between basic and clinical neuroscientists.”<\/p>\n PsychCentral. New\u00a0Pharmacological Approach for\u00a0Binge Eating. Laboratory of Addictive Disorders <\/a>identify new therapeutic approach.<\/p>\n Sciencedaily<\/a>: Impulsivity is a risk factor for food addition.<\/p>\n Huffington Post<\/a>: Could Impulsive Behavior Lead to Food Addiction?<\/p>\n Boston University School of Medicine<\/a>. Researchers\u00a0in the Laboratory of Addictive Disorders have discovered that impulsivity is a risk factor for food addiction . Results of the study, published online in\u00a0Neuropsychopharmacology\u00a0<\/em><\/a>, suggest that impulsivity promotes pathological overeating.<\/p>\n Researchers Show that CRF in the Amygdala is Responsible for Compulsive Overeating<\/a><\/p>\n Neuropsychopharmacology: <\/a><\/em>BUSM Researchers Discover Possible Mechanism for Anxiety and Depressio<\/a>n<\/p>\n \u00a0NIDAIRP Hot Paper, November 2012<\/a>: Antagonism of Sigma-1 Receptors Blocks Compulsive-Like Eating<\/p>\n Boston University School of Medicine: Yahoo! News: Addiction Drug Could Curb Binge Eating<\/a>.<\/p>\n Science Daily: Role of Cellular Protein Demonstrated in Regulation of Binge Eating<\/a>.<\/p>\n Forbes: Obesity’s Hazards And Mysteries<\/a><\/p>\n FoxNews: Overeaters, Drug Abusers Share Addictive Brain Chemistry<\/a><\/p>\n ScienceNow: Chocolate Cake: The New Heroin?<\/a><\/p>\n NIH, News in Health: Restricting Sugary Food May Backfire<\/a><\/p>\n BU Today: The Binge Eater as Junkie<\/a><\/p>\n Boston University: Pietro Cottone receives BUSM Peter Paul Career Development Professorship Award<\/a><\/p>\n![\"\"](\"\/ppb\/files\/2022\/05\/LAD_Diagrams-650x253.jpg\")
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\nThe LAD is committed to:
\no\u00a0\u00a0 Conduct research<\/em> that expands our understanding of the pathophysiology and prevention of psychiatric diseases, and apply this to the development of novel therapeutics.
\no\u00a0\u00a0 Provide outstanding and multidisciplinary training<\/em> to graduate and undergraduate students.<\/p>\n
\nBoston University Ph.D. Program in Biomolecular Pharmacology<\/span><\/a><\/strong>
\nBoston University Graduate Program for Neuroscience<\/span><\/a><\/strong><\/p>\nPeople<\/h3>
<\/p>\nPrincipal Investigators<\/h3>\n
\n\t\t\t\t\t\n
![\"\"](\"\/ppb\/files\/2010\/11\/10-3009-PHARMAHEAD_Cottone-022.jpg\")
<\/figure>\t\t\t\tPietro Cottone, Ph.D.<\/h6>\n\t\t
![\"\"](\"\/ppb\/files\/2012\/06\/10-3009-PHARMAHEAD-087_2.jpg\")
<\/figure>\t\t\t\tValentina Sabino, Ph.D.<\/h6>\n\t\t
Research Staff<\/h3>\n
\n![\"\"](\"\/ppb\/files\/2020\/02\/Sema-Quadir-150x150.jpg\")
Sema Quadir <\/strong>(Ph.D. Candidate, Graduate Program in Biomolecular Pharmacology), B.S., University of Santa Barbara, CA. sgquadir@bu.edu<\/a><\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/MargaretMinnig-1-150x150.jpg\")
Margaret Minnig<\/strong> (M.D.\/Ph.D. Candidate, Graduate Program for Neuroscience Ph.D.)\u00a0mminnig@bu.edu<\/a><\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/Harrison-Lee-1-150x150.jpg\")
Harrison Lee<\/strong> (Masters of Medical Sciences Graduate Student)\u00a0hsl9@bu.edu<\/a><\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/EmilyErhard_Headshot-150x150.jpg\")
Emily Erhard<\/strong> (Northeastern University Co-Op student) erharde@bu.edu<\/a><\/div>\n<\/div>\nAlumni<\/h3>\n
\n![\"\"](\"\/ppb\/files\/2010\/11\/Ali-Al-Abdullatif-150x150.jpg\")
Ali Al Abdullatif,<\/strong> Research Associate, Massachusetts Institute of Technology, Cambridge, MA<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Angelo-Blasio_2-150x150.jpg\")
Angelo Blasio, Ph.D.<\/strong>, Project Manager, Beth Israel Deaconess Medical Center, Boston, MA<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Alyssa-Dileo-150x150.jpg\")
Alyssa Dileo<\/strong>, Ph.D. Candidate, Tufts University, Boston, MA<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Riccardo-Dore-150x150.jpg\")
Riccardo Dore, Ph.D.,<\/strong> Post-doctoral fellow University of L\u00fcbeck, Hamburg, Germany<\/span><\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/MariaEcheveste-150x150.jpg\")
Maria Echeveste, <\/strong>Undergraduate Student, Northeastern University<\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/Aidan-Evans-Strong-e1652643164469-150x150.jpg\")
Aidan Evans-Strong,\u00a0<\/strong>Undergraduate Student, Northeastern University<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Pic_Ferragud-150x150.jpg\")
Antonio Ferragud Faus, Ph.D.,<\/strong> Department of Psychology, University of Cambridge, U.K.<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Callum_Photo-150x150.jpg\")
Callum Hicks, Ph.D.,<\/strong> Assistant Professor of Psychology and Neuroscience, Lawrence University, Appleton, WI<\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/Adam-Howell_Alumnus-150x150.jpg\")
Adam Howell,<\/strong> M.D. Candidate<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Attilio-Iemolo-150x150.jpg\")
Attilio Iemolo, Ph.D.,<\/strong> Senior Postdoctoral Scientist, University of California San Diego, CA<\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/Kayhan-150x150.jpg\")
Kayhan Kaybay,\u00a0<\/strong>Undergraduate Student, Northeastern University<\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/Rachel-Leavitt_Alumnus-150x150.jpg\")
Rachel Leavitt,\u00a0<\/strong>M.D. Candidate<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Cassie-Moore-150x150.jpg\")
Cassie Moore, Ph.D.,<\/strong> Postdoctoral Fellow, The Johns Hopkins School of Medicine, Baltimore, MD<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Aditi1.jpg\")
Aditi Narayan,<\/strong> Scientist, San Francisco, CA<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Rahul-Rao.jpg\")
Rahul Rao, M.D.,<\/strong> Resident Physician, University of Pittsburgh Medical Center, Pittsburgh, PA<\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/MadisonRiley-150x150.jpg\")
Madison Riley<\/strong>, Undergraduate, Northeastern University<\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/Chris-Rohl_Alumnus-150x150.jpg\")
Chris Rohl,\u00a0<\/strong>M.D. Candidate<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Pic_Velazquez-150x150.jpg\")
Clara Vel\u00e1zquez Sanchez, Ph.D.<\/strong>, Research Associate, Department of Psychology, University of Cambridge, Cambridge, U.K.<\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/Gabrielle-Schlain_Alumnus-150x150.jpg\")
Gabrielle<\/strong> Schlain<\/strong>, M.D. Candidate<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Mariel-Seiglie-150x150.jpg\")
Mariel Seiglie, Ph.D.,<\/strong> Postdoctoral Research Fellow, Boston Children’s Hospital\/Harvard Medical School, Boston, MA<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/KarenSmith-150x150.jpg\")
Karen Smith Watts, Ph.D.,<\/strong> Senior Scientist, Disease Biology, at Alkermes, Waltham, MA<\/div>\n![\"\"](\"\/ppb\/files\/2020\/02\/Sean-Tanino_Alumnus-150x150.jpg\")
Sean Tanino<\/strong>, M.D. Candidate, Duke University School of Medicine, Durham, NC<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Marta-Valenza_21-142x150.jpg\")
Marta Valenza, Ph.D.,<\/strong> Research Fellow, La Sapienza University, Rome, Italy, and Epitech Group, Padova, Italy<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Xiaofan-Wang-150x150.jpg\")
Xiaofan Wang, Ph.D.,<\/strong> Clinical Research Specialist II, Boston Children’s Hospital<\/div>\n![\"\"](\"\/ppb\/files\/2010\/11\/Tamara-Zeric-150x150.jpg\")
Tamara Zeric, Ph.D.<\/strong> Candidate and NSF Research Fellow, Columbia University, New York, NY<\/div>\n<\/div>\nContact<\/h3>
<\/p>\nSelected Peer-Reviewed Publications<\/h3>
<\/p>\n
\n.
\nIemolo A, Valenza M, Tozier L, Knapp CM, Kornetsky C, Steardo L, Sabino V, Cottone P. Withdrawal from chronic, intermittent access to a highly palatable food induces depressive-like behavior in compulsive eating rats. Behav Pharmacol. <\/em>2012 Sep;23(5-6):593-602. PubMed PMID: 22854309.<\/p>\n
\n*<\/strong>The paper has been evaluated by the Faculty of 1000 Biology: 9, Excellent<\/span>. Heilig, Markus<\/em> <\/a>.<\/p>\nNews<\/h3>
<\/p>\n
\nBUSM Researchers Find Drug Used for Addiction Treatment May Block Binge Eating Impulse<\/a>.<\/p>\n