{"id":24750,"date":"2026-07-23T12:59:59","date_gmt":"2026-07-23T16:59:59","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/ppb\/?page_id=24750"},"modified":"2026-07-23T13:00:35","modified_gmt":"2026-07-23T17:00:35","slug":"24750-2","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/ppb\/24750-2\/","title":{"rendered":""},"content":{"rendered":"<h3>PhD or MA in Physiology or Biophysics<\/h3>\n<p>Boston University Chobanian &amp; Avedisian School of Medicine offers<br \/>\nprograms leading to a PhD or an MA in Physiology or Biophysics. Each<br \/>\nprogram stresses laboratory training and original research performed<br \/>\nunder the direction of a faculty member, as well as satisfactory<br \/>\nperformance in graduate coursework.<br \/>\nIn the first and second years of both the PhD and MA programs, a core<br \/>\ncurriculum of Foundations in Biomedical Sciences courses is<br \/>\nsupplemented with biophysics and physiology. The program emphasizes<br \/>\nflexibility and individual choice. In the first year, students do research<br \/>\nrotations in the laboratories of 3\u20134 (PhD) or 2\u20133 (MA, optional) faculty<br \/>\nmembers to gain firsthand knowledge of a variety of research areas.<br \/>\nAt the end of the first year, students select a degree advisor and<br \/>\ncontinue research toward the MA or PhD degree. In the second year<br \/>\nstudents continue to take courses and PhD students must pass a<br \/>\nqualifying exam. Throughout their training, students also participate in a<br \/>\nweekly department seminar series and report their research progress<br \/>\nannually at a student seminar day.<\/p>\n<h4>Learning Outcomes<\/h4>\n<ul>\n<li>All students graduating with the PhD in Physiology or Biophysics from<br \/>\nthe Chobanian &amp; Avedisian SOM are expected to:<\/li>\n<li>Generate an original body of work in the biomedical sciences that reflects critical<br \/>\nthinking and independent thought.<\/li>\n<li>Demonstrate competencies in advanced research skills.<\/li>\n<li>Develop the ability to communicate in both written and oral methods within their<br \/>\nchosen field of expertise with both specialists and nonexperts.<\/li>\n<\/ul>\n<p>Demonstrate a commitment to professional development and continued learning in<br \/>\ntheir chosen field.<\/p>\n<p>All students graduating with the MA in Physiology or Biophysics from<br \/>\nthe Chobanian &amp; Avedisian School of Medicine are expected to:<\/p>\n<ul>\n<li>Generate an original body of work or a library thesis in physiology or biophysics that<br \/>\nreflects critical thinking and independent thought.<\/li>\n<li>Demonstrate competencies in research skills or library research skills.<\/li>\n<li>Develop the ability to communicate through written documents within their chosen<br \/>\nfield of expertise with both specialists and nonexperts.<\/li>\n<li>Demonstrate a commitment to professional development and continued learning in<br \/>\ntheir chosen field.<\/li>\n<\/ul>\n<h4>Purpose and Background<\/h4>\n<p>The department, under the aegis of Dr. Venetia Zachariou as chair,<br \/>\nbrings together active faculty members to provide excellence in research<br \/>\nand graduate education. Research interests in the department span the<br \/>\nmodern areas of cellular physiology and molecular biophysics, with<br \/>\nstrong concentrations in structural biology, vision research, muscle<br \/>\nphysiology, neurophysiology, and the biology and physical chemistry of<br \/>\nproteins, lipids, and lipoproteins. Faculty members are nationally and<br \/>\ninternationally recognized as leaders in their areas of research. The<br \/>\ndepartment provides flexible graduate programs with pathways either<br \/>\nleading toward a degree in physiology or in biophysics. The department<br \/>\noffers these two programs in a strong, collegial environment to<br \/>\nencompass and promote the diverse overlapping research of all<br \/>\nmembers of the department.<\/p>\n<p>The goal of our programs in Physiology or Biophysics is to produce<br \/>\ngraduate students who understand the thermodynamic, chemical,<br \/>\nelectrical, and structural aspects of biological systems at the atomic level<br \/>\nand in the context of the cell and organism. The training across scientific<br \/>\nand medical disciplines provides graduates the advantage of learning<br \/>\nphysiology and biophysics in the context of the regulation of<br \/>\nhomeostasis and pathogenicity of the cell, and of the organism as a<br \/>\nwhole. Graduates will be able to communicate and collaborate effectively<br \/>\nwith a broad range of disciplines ranging from medical personnel to<br \/>\nchemists, engineers, and physicists.<\/p>\n<p>A set of required core courses will be taken by the students in the first<br \/>\nand\/or second year that will lead to a level of understanding of the two<br \/>\ndisciplines necessary for a degree in physiology or biophysics. After<br \/>\ncompleting the core course requirements, students have flexibility to<br \/>\nchoose the appropriate additional coursework for their interests, within<br \/>\nthe guidelines set out below. The courses for first-year students are<br \/>\nchosen with the guidance of members of the Student Admissions &amp;<br \/>\nAffairs Committee (SAAC), and in the second year with input from their<br \/>\nPhD or MA advisor. Students who successfully complete the program<br \/>\nare awarded either a PhD or an MA in Physiology or in Biophysics.<\/p>\n<p><strong>Similar Paths for PhD, MD\/PhD, and Post-MA PhD<\/strong><br \/>\n<strong>students<\/strong><\/p>\n<p>Requirements for PhD and MD\/PhD students are similar. Students in the<br \/>\nPhD program take their qualifying examination in their second year.<br \/>\nMD\/PhD students enter after completing the second-year Medical<br \/>\nCurriculum and are therefore treated as post-MA students with a lower<br \/>\ncourse and unit requirement (32 versus 64 total units), and take their<br \/>\nqualifying exam at the end of their first year in the program.<\/p>\n<p>Transfer and post-MA students are handled on a case-by-case basis,<br \/>\nand may be able to take the qualifying examination at the end of their<br \/>\nfirst year.<\/p>\n<p>In all cases, post-MA students are able to choose a suitable set of<br \/>\ncourses tailored to their backgrounds and research interests, with input<br \/>\nfrom the SAAC during the first year and from their advisor in following<br \/>\nyears.<\/p>\n<h4>The MA Programs<\/h4>\n<p>MA programs in Physiology or Biophysics are offered. In some cases, a<br \/>\nqualified MA student may subsequently apply to the Program in<br \/>\nBiomedical Sciences (PiBS) PhD program. This decision is dependent<br \/>\non the student\u2019s application and acceptance into the PiBS umbrella<br \/>\nprogram through the PiBS admissions process.<\/p>\n<p>An MA requires 32 unit hours (paid for by the student) and requires<br \/>\neither a literature-based dissertation or a short laboratory-based<br \/>\ndissertation with two readers from within the department.<\/p>\n<h3>The Path of a Graduate Student<\/h3>\n<p>On joining the department, students follow a path of requirements with<br \/>\nspecific coursework dependent on their concentration in either<br \/>\nPhysiology or Biophysics. Students with a concentration in Physiology<br \/>\nare required to take at least one course in Biophysics and students with<br \/>\na concentration in Biophysics take at least one course in Physiology.<\/p>\n<p>Seminar Courses (GMS BY 871, 872 or GMS PH 841,<br \/>\n842; 2 units per term)<\/p>\n<p>In the second year (required) and additional years (optional), all students<br \/>\nin the department participate in the Special Topics Seminar course,<br \/>\naimed at developing the student\u2019s ability to read the scientific literature<br \/>\nand present the merits and\/or deficits of a current research paper to<br \/>\nother students and a proctoring faculty member. The students use a<br \/>\nwhiteboard and computer for their presentations. This component of the<br \/>\ncourse meets for one hour each week, as specified by the faculty<br \/>\nmember proctoring the class. Typically, all students present at least once<br \/>\neach term, and possibly more often, based on the number of enrolled<br \/>\nstudents. Additionally, students are taught to write grants, research<br \/>\npapers, and more general scientific articles such as \u201cNews and Views\u201d<br \/>\non papers from the current literature. An important complement to the<br \/>\nstudent presentations is required attendance at the Department Seminar<br \/>\nSeries where the students are exposed to cutting-edge research by<br \/>\noutstanding speakers.<\/p>\n<p>All graduate students in the department earn 2 graded units per term.<\/p>\n<p>The faculty member who teaches this course is rotated after each term,<br \/>\nto allow a fresh viewpoint and area of expertise to be covered. The Chair<br \/>\nof the SAC, with input from the Program Steering Committee, selects 6\u2013<br \/>\n8 faculty who are interested in teaching this course on a rotating basis.<\/p>\n<h4>Student Seminars<\/h4>\n<p>In years 3\u20135, or starting with the spring term after the qualifying<br \/>\nexamination has been completed, all PhD candidates will present a 20\u2013<br \/>\n30-minute seminar on their dissertation research. These seminars form a<br \/>\nlogical extension of the departmental Seminar Series and the Special<br \/>\nTopics course and take place on a specified Student Seminar Day (or<br \/>\ndays). Predissertation committee members for a presenting student take<br \/>\nnotes on the quality of the presentation and meet with the student within<br \/>\n2\u20133 days, on either a one-to-one basis or in small groups with other<br \/>\ncommittee members, to provide feedback with the goal of improving the<br \/>\nstudent\u2019s presentation skills.<\/p>\n<h4>Student Poster Presentations<\/h4>\n<p>Students who have completed their qualifying exams present a poster<br \/>\nduring Russek Day in the spring of each year, to improve their<br \/>\norganization and presentation skills. In addition, students are<br \/>\nencouraged to enter their posters in the Scholars\u2019 Day poster<br \/>\ncompetition held at the Boston University Charles River Campus.<br \/>\nStudents are encouraged to attend local and national meetings to<br \/>\npresent their research.<\/p>\n<h4>Student Individual Development Plans and Professional<br \/>\nDevelopment<\/h4>\n<p>Students, together with Student Affairs committee members, each create<br \/>\nan individual development plan that is updated at least annually. The<br \/>\nProfessional Development and Postdoctoral Affairs office provides<br \/>\nmonthly workshops, lectures, and panel discussions, which students are<br \/>\nencouraged to attend as they progress through the program.<\/p>\n<h3>Course Requirements<\/h3>\n<p>Incoming PhD and MA students are required to take either five or three<br \/>\nmodules, respectively, from the Foundations in Biomedical Sciences<br \/>\ncurriculum, including Protein Structure, Cell Dynamics, Genetics and<br \/>\nGenomics, Mechanisms of Cell Communication, and Cellular Physiology<br \/>\n(GMS FC 701, 702, 703, 704, and 707 for PhD; FC 701, 703, and 704<br \/>\nfor MA). PhD and MA students must take a statistics course (e.g. GMS<br \/>\nMS700 or MS75); MA students may meet this requirement through an<br \/>\nundergraduate statistics course.To allow flexibility for the breadth of the<br \/>\nfields of physiology and biophysics, yet ensure a working knowledge of<br \/>\nboth, students are required to take a minimum of one physiology course<br \/>\nand one biophysics course.<\/p>\n<p>The acceptable biophysics courses are:<\/p>\n<ul>\n<li>GMS BY 760 A Macromolecular Assemblies: Protein-Protein, Protein-Nucleic Acid,<br \/>\nand Membrane Protein Assemblies (2 units)]<\/li>\n<li>GMS BY 760 B Macromolecular Assemblies: Lipid-Protein Assemblies (2 units)<\/li>\n<li>GMS BY 771 B Foundations of Structural Biology: Computation, Thermodynamics,<br \/>\nSpectroscopy, and NMR (2 units)<\/li>\n<li>GMS PH 771 A Foundations of Structural Biology: Structure Determination byCrystallography and Electron Microscopy (2 units)The acceptable physiology courses are:<\/li>\n<li>GMS FC 707 Physiology of Specialized Cells (3 units)<\/li>\n<li>GMS PH 730 Human Physiology A (4 units)<\/li>\n<li>GMS PH 731 Human Physiology B (4 units)<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>Elective coursework is chosen jointly by the student and their advisor or<br \/>\ndissertation committee. To achieve a balanced curriculum for all<br \/>\nstudents, Graduate Medical Sciences PhD degree requirements include<br \/>\na minimum of 24 units in formal coursework, or 12 units for the post-MA.<br \/>\nIt is expected, although not required, that the formal coursework units<br \/>\nare acquired prior to the qualifying examination at the end of the second<br \/>\nyear. Beyond 24 coursework units, students are encouraged to<br \/>\ninformally audit courses following consultation with their dissertation<br \/>\ncommittee. Post-MA students who have already taken an appropriate<br \/>\ngraduate-level course in the core curriculum are permitted to substitute<br \/>\nan elective or electives in the first term.<\/p>\n<h3>The Qualifying Examination<\/h3>\n<p>Success in science requires that students be able to express their<br \/>\nthoughts both verbally and in written form. The necessary verbal skills<br \/>\nare developed through participation in the Special Topics Seminar<br \/>\ncourse and by giving presentations in yearly research seminars at the<br \/>\nStudent Seminar Day(s), laboratory group meetings, predissertation<br \/>\nmeetings, and the dissertation defense seminar. Written skills are<br \/>\ndeveloped in required coursework and in the writing of papers and the<br \/>\ndissertation. This process begins with the writing of a research proposal<br \/>\nusing the NIH National Research Service Award (NRSA) or American<br \/>\nHeart Association Research Training Grants and Fellowships format, to<br \/>\nfulfill the written qualifying exam requirement.<\/p>\n<p>The qualifying examination is given at the end of the second term within<br \/>\nthe second year for PhD students. MD\/PhD, post-MA, and some transfer<br \/>\nstudents in the PhD program have the option of taking the qualifying<br \/>\nexamination at the end of the second term of the first year.<\/p>\n<p>Administration of the qualifying examination will be overseen by the<br \/>\nSAAC. Program faculty members serve on the qualifying examination<br \/>\ncommittees on a rotating basis. The two-part exam consists of:<\/p>\n<ol>\n<li>For the written qualifying examination, students write a research proposal that<br \/>\ncorrelates with, but may or may not include, their planned dissertation research.<br \/>\nThis document is judged by three members of the SAAC committee for the<br \/>\nstudent\u2019s understanding of the relevant scientific literature and ability to propose<br \/>\ntestable scientific hypotheses.<\/li>\n<li>For the oral examination, a five member examination committee will ask questions<br \/>\nto test the student\u2019s ability to think critically about their chosen research field,<br \/>\nincluding the scientific methods, theory, and background of the proposed research.<br \/>\nIn addition to assessing the student\u2019s understanding of their proposed research, the<br \/>\noral qualifying exam committee can ask general concept questions to help them<br \/>\nassess the student\u2019s knowledge of their area of concentration, as well as their<br \/>\nfoundational knowledge in appropriate areas of the biomedical sciences, including<br \/>\ncell physiology, biophysics, biochemistry, etc. Dissertation advisors will not<br \/>\nparticipate in the oral defense of students who are pursuing a PhD in their<br \/>\nlaboratory. The oral examination is given 2-4 weeks after the due date of the written<br \/>\nexamination.<\/li>\n<\/ol>\n<p>Both the written and oral portion of the qualifying exam must be passed<br \/>\nin order for a student to continue in the PhD program. Students who fail<br \/>\neither the oral or the written portion of the exam (or both) can retake that<br \/>\nportion of the exam once in order to achieve a passing score. MA<br \/>\nstudents do not take the qualifying examination.<\/p>\n<h3>Dissertation<\/h3>\n<h4>Predissertation Meetings<\/h4>\n<p>After the student has passed the qualifying exam, a predissertation<br \/>\ncommittee of at least five members must be established in the fall of that<br \/>\nyear and submitted to the SAAC. Students submit their dissertation<br \/>\nproposal in grant form to the members of the committee two weeks<br \/>\nbefore the first predissertation committee meeting. At least one member<br \/>\nfrom outside the department, and preferably from a different institution,<br \/>\nshould be included in the final dissertation committee. An external<br \/>\ncommittee member is not required for predissertation meetings, which<br \/>\nwill be held about every 10\u201312 months or at least three times prior to<br \/>\ngraduation.<\/p>\n<h4>Dissertation Defense<\/h4>\n<p>The PhD dissertation defense consists of a public seminar followed by a<br \/>\nclosed-door dissertation defense with a minimum of five committee<br \/>\nmembers, including one member from outside the department.<\/p>\n<h3>Program Resources<\/h3>\n<p>All members of the faculty of the department participate in the graduate<br \/>\nprograms in Physiology or Biophysics. The faculty have well-funded<br \/>\nresearch programs and extensively equipped individual laboratories for<br \/>\ncarrying out research in cellular physiology and biophysics. In addition,<br \/>\nthe department maintains core facilities in molecular biology,<br \/>\nspectroscopy, NMR, and structural electron microscopy that will be used<br \/>\nby students carrying out their research.<\/p>\n<h3>Admission<\/h3>\n<p>Recruitment directly into the Program in Biomedical Sciences is the<br \/>\nroute of entry for PhD students, and MA candidates apply directly to our<br \/>\nprograms in Physiology or in Biophysics.<\/p>\n<p>There is no strict formula for acceptance to the programs, and many<br \/>\nfactors go into the Admissions Committee\u2019s decisions. The programs<br \/>\nseek students from a wide range of backgrounds including physics,<br \/>\nchemistry, biochemistry, biology, and medical sciences.<\/p>\n<p>For acceptance into the program, students should have outstanding<br \/>\ngrades in a rigorous curriculum, and applicants should have completed<br \/>\norganic chemistry, physics, and physical chemistry courses. The GRE<br \/>\ngeneral test and subject tests are not required. Foreign students are<br \/>\nrequired to take the TOEFL. We are especially interested in candidates<br \/>\nwith research experience. Finally, the letters from the applicant\u2019s<br \/>\nreferences are extremely important, as is the applicant\u2019s personal<br \/>\nstatement. Underrepresented minorities are encouraged to apply.<\/p>\n<h3>Administration<\/h3>\n<p>The chair of the department is the director of the graduate programs and<br \/>\nhas the ultimate responsibility for administering the graduate programs in<br \/>\nPhysiology or Biophysics. A Program Steering Committee oversees the<br \/>\ngraduate programs and advises the Chair of the Student Admissions &amp;<br \/>\nAffairs Committee (SAAC) on specific needs of the programs. Steering<br \/>\nCommittee members select faculty members to serve on the SAAC and<br \/>\noversee the appointment of committees that deal with developing new<br \/>\ncourses along with the review and updating of existing courses.<\/p>\n<p>The Steering Committee and the SAAC Chair work jointly to supervise<br \/>\nthe appointment of faculty to run the departmental seminar series and<br \/>\nplan the departmental retreat. Student Seminar Days are organized by<br \/>\nfaculty members who are running the department seminar series in a<br \/>\ngiven year.<\/p>\n<h3>The Student Admissions &amp; Affairs<br \/>\nCommittee (SAAC)<\/h3>\n<p>The SAAC oversees the day-to-day operations of the graduate<br \/>\nprograms, including: student recruitment, admissions, orientation,<br \/>\nrotations, assignment of dissertation advisors, and qualifying<br \/>\nexaminations. The SAAC is comprised of 5\u20137 faculty members who<br \/>\nadequately represent the diverse research interests within the<br \/>\ndepartment.<\/p>\n<p>The SAAC serves many roles in the department. The SAAC is charged<br \/>\nwith overseeing student affairs and academic standing, curriculum<br \/>\ndevelopment, and administering the qualifying examination. The SAAC<br \/>\nis also available to help with student problems and to mediate issues<br \/>\nbetween students and advisors.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>PhD or MA in Physiology or Biophysics Boston University Chobanian &amp; Avedisian School of Medicine offers programs leading to a PhD or an MA in Physiology or Biophysics. Each program stresses laboratory training and original research performed under the direction of a faculty member, as well as satisfactory performance in graduate coursework. In the first [&hellip;]<\/p>\n","protected":false},"author":1811,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"page-templates\/no-sidebars.php","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/pages\/24750"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/users\/1811"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/comments?post=24750"}],"version-history":[{"count":6,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/pages\/24750\/revisions"}],"predecessor-version":[{"id":24756,"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/pages\/24750\/revisions\/24756"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/ppb\/wp-json\/wp\/v2\/media?parent=24750"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}