{"id":13,"date":"2008-08-11T21:49:16","date_gmt":"2008-08-12T01:49:16","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/pneumonia\/research\/publications\/"},"modified":"2026-03-25T17:51:27","modified_gmt":"2026-03-25T21:51:27","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/pneumonia\/research\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>Shastry*, A, BE Hiller*, NL Sanders, AE Tseng, J Kothari, AK O\u2019Connell, HP Gertje, CT Ha, E Murzin, KE Traber, JA Lederer, MR Jones, F Douam, TG Beach, DG Remick, NA Crossland, S Monti, JD Campbell, JP Mizgerd. 2026. Sub-phenotypes of pneumonia defined by pulmonary histopathological features. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.05.18.654716v1\" target=\"_blank\" rel=\"noopener\"><em>bioRxiv<\/em><\/a>\u00a0and <em>Am J Respir Crit Care Med<\/em> (in press). *co-first authors<\/p>\n<p>Grifno, GN, HA Kahvecioglu, V Travnik, R LeBourdais, R Banerji, W Wangsrikhun, L Shi, S Bozal, A Batgidis, A Kobayter, L Castle, K Regan, JP Mizgerd, W Longest, M Hindel, M Saltzman, J Butler, B Suki, HT Nia. 2026. Mosaic pattern: lung functional heterogeneity at the alveolus level. <em><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.10.13.682072v1\" target=\"_blank\" rel=\"noopener\">bioRxiv<\/a>\u00a0<\/em>and <em>Nat Biomed Eng\u00a0<\/em>(in press).<\/p>\n<p>Mizgerd, JP. 2026. Host pathogen interactions leading to pneumonia pathogenesis. <em>Clin Chest Med<\/em> (in press). <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0272523125001078?dgcid=author\" target=\"_blank\" rel=\"noopener\">Full Text<\/a> <strong>available for free until May 14, 2026<\/strong><\/p>\n<p><span>Hayes, KM, K Boldt, PJ Schnorr, P Bawa, M Abyazi, MS Ware, G Gyimesi, M James, HM Ko, C Cunningham-Rundles, JP Mizgerd, G Mostoslavsky, DN Kotton, PJ Maglione. 2026. Heterozygous NFKB1 variant causes inflammatory dysregulation shaped by broader genetic context in common variable immunodeficiency. <i>JCI Insight<\/i> 11(6):e198703. <a href=\"https:\/\/insight.jci.org\/articles\/view\/198703\" target=\"_blank\" rel=\"noopener\">Full Text<\/a><\/span><\/p>\n<p>Armstrong, EMR, JP Mizgerd. 2026. Helping alveolar macrophages live to fight another day during viral pneumonia. <em>J Clin Invest<\/em> 136(2):e201457. <a href=\"https:\/\/www.jci.org\/articles\/view\/201457\" target=\"_blank\" rel=\"noopener\">Full Text<\/a><\/p>\n<p>Tabackman, A, C Acu\u00f1a-Villaordu\u00f1a, M Canning, M Karoly, MR Dauphinais, R Michaud, TC Bouton, DL Bourque, KA Reifler, V Sabharwal, K Traber, AN Gupte, KR Jacobson, P Sinha. 2026. Low TB1 and TB2 antigen-nil is associated with increased QuantiFERON Gold Plus reversions. <em>Int J Tuberc Lung Dis<\/em> 30:88-89. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41618115\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a><\/p>\n<p>Martins, MF, JM Teran Plasencia, KR Jacobson, TC Bouton, KE Traber, M Canning, DL Bourque, V Sabharwal, R Michaud, P Sinha, CJ Acu\u00f1a-Villaordu\u00f1a. 2026. Shorter regimens for TB preventive treatment: implementation challenges and priorities. <em>Int J Tuberc Lung Dis<\/em> 30:43-44. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41482619\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a><\/p>\n<p>Arnold, C, ME McCartney, CE Davis, JP Mizgerd, NJ Kenyon. 2025. Harnessing breath biomarkers for pneumonia diagnosis and prognosis. <i>Exp Rev Respir Med <\/i>26:1-10. <a href=\"https:\/\/www.tandfonline.com\/doi\/10.1080\/17476348.2025.2593629?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed#abstract\" target=\"_blank\" rel=\"noopener\">Full text<\/a><\/p>\n<p>Samarasinghe, AE, SH Randell, HS Kulkarni, JN Weiser, LJ Quinton, RP Dickson, JP Mizgerd, CJ Orihuela, D Parker, KM Robinson, AS Prince, SE Evans, JK Kolls, JS Lee, A Torres, LA Miller, DJ Hamilton, M Gomez, BB Moore, RL Walker, LJ Barkal, S Jeyaseelan, GW Lau, J Sharma, M Witzenrath, CS Dela Cruz. 2025. Best Practices in the Development and Use of Animal Models of Bacterial Pneumonias: An Official American Thoracic Society Workshop Report. <em>Am J Respir Cell Mol Biol<\/em> 73:178-199. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40748059\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Caobi, A, CM Su, CM Beusch, D Kenney, T Darling, S Feng, M Semaan, A Wacquiez, N Sanders, E Tully, DY Chen, M Evdokimova, Z Ding, D Jones, KD Alysandratos, JP Mizgerd, RN Kirchdoerfer, DN Kotton, F Douam, NA Crossland, J Boon, DE Gordon, SC Baker, M Saeed. 2025. SARS-CoV-2 nsp15 enhances viral virulence by subverting host antiviral defenses. <em>PNAS<\/em> 122(24):e2426528122. <a href=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.2426528122?url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org&amp;rfr_dat=cr_pub++0pubmed\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/span><\/span><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Traber, KE, JP Mizgerd. 2025. The integrated pulmonary immune response to pneumonia. <em>Annu Rev Immunol<\/em> 43(1):545-569. <a href=\"http:\/\/chrome-extension:\/\/efaidnbmnnnibpcajpcglclefindmkaj\/https:\/\/www.annualreviews.org\/deliver\/fulltext\/immunol\/43\/1\/annurev-immunol-082323-031642.pdf?itemId=\/content\/journals\/10.1146\/annurev-immunol-082323-031642&amp;mimeType=application\/pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/span><\/span><\/p>\n<p>Martins MF, Teran Plasencia JM, Jacobson KR, Bouton TC, Traber KE, Canning M, Bourque DL, Sabharwal V, Michaud R, Sinha P, Acu\u00f1a-Villaordu\u00f1a CJ. 2025. Rifampin versus isoniazid completion rates for TB infection. <span><em>Int J Tuberc Lung Dis<\/em> 29:425-427<\/span>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40883884\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a><span><\/span><\/p>\n<p>Brimhall, KC, K Kuhfeldt, DN Kotton, MR Jones. 2025. Building on the Translational Science Benefits Model to include team science: a practical and theory-based approach to continuous quality improvement and impact evaluation for Clinical and Translational Science Award programs. <span><em>Front Public Health<\/em> 13:1581205. <a href=\"https:\/\/www.frontiersin.org\/journals\/public-health\/articles\/10.3389\/fpubh.2025.1581205\/full\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/p>\n<p>Fredberg, JJ, JP Mizgerd. 2025. Combining innovative methodologies with deep personal connections to further physiology research: Lessons from Joseph D. Brain, ScD. <em>Am J Physiol: Lung Cell Mol Physiol <\/em><span>329(2):L197-L199<\/span>. <a href=\"https:\/\/journals.physiology.org\/doi\/abs\/10.1152\/ajplung.00281.2024?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Henao Vasquez, J, J Yuan, CJ Leow, E Crossey, F Shao, S Carty, VA Dominguez, M Lo, JP Mizgerd, JL Fetterman, NC Lau, A Fine, MR Jones. 2025. Somatic MIWI2 modulates mitochondrial function in airway multiciliated cells and exacerbates influenza pathogenesis.<em> iScience<\/em> 28(4):112291. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2589004225005528?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/span><\/span><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Soucy, AM, JE Brune, A Jayaraman, AT Shenoy, FT Korkmaz, NS Etesami, BE Hiller, IMC Martin, EN Niszczak, WN Goltry, CT Ha, NA Crossland, JD Campbell, TG Beach, KE Traber, MR Jones, LJ Quinton, M Bosmann, CW Frevert, JP Mizgerd. 2025. Transcriptomic responses of lung mesenchymal cells during pneumonia. <em>JCI Insight<\/em> 10(7):e177084. <a href=\"https:\/\/insight.jci.org\/articles\/view\/177084\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/span><\/span><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Gilbert, KM, RF LeCates, AA Galbraith, PJ Maglione, S Argetsinger, NL Rider, JR Farmer, MS Ong. Diagnostic disparities in inborn errors of immunity: From clinical suspicion to diagnosis. <em>J Allergy Clin Immunol Glob<\/em> 4(2):100407. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772829325000086?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/span><\/span><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Ravi, VR, FT Korkmaz,<sup> <\/sup>C Lyon De Ana, L Lu, F Shao, CV Odom, KA Barker, A Ramanujan, WN Goltry, IMC Martin, CT Ha, LJ Quinton, MR Jones, A Fine, JD Welch, F Chen, AC Belkina, JP Mizgerd*, AT Shenoy*. 2025. Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airways neutrophilic disease. <em>Cell Reports<\/em> 44(3):115294. *co-corresponding authors <a href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(25)00065-8\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/span><\/span><\/p>\n<p><span class=\"value ng-star-inserted\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Gutzeit C, Grasset EK, Matthews DB, Maglione PJ, Britton GJ, Miller H, Magri G, Tomalin L, Stapylton M, Canales-Herrerias P, Sominskaia M, Guzman M, Pybus M, Tejedor Vaquero S, Radigan L, Tach\u00f3-Pi\u00f1ot R, Mart\u00edn Nalda A, Garc\u00eda Prat M, Martinez Gallo M, Dieli-Crimi R, Clemente JC, Mehandru S, Suarez-Farinas M, Faith JJ, Cunningham-Rundles C, Cerutti A. 2025. <\/span><\/span><\/span>Gut IgA functionally interacts with systemic IgG to enhance antipneumococcal vaccine responses. <span><em>Sci Adv<\/em> 11:eado9455. <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.ado9455?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/p>\n<p><span class=\"value ng-star-inserted\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Nieto-Patl\u00e1n A, Ross J, Mohan S, Paczosa MK, Soliman R, Sarmento O, Aliu E, Thiyagarajan L, Chandra A, Picard C, Warnatz K, Jolles S, Lesmana H, Maglione PJ, Platt CD, Sediva A, Sullivan KE, Zhang K, Raval F, Tangye SG, Abraham RS. 2025.\u00a0<\/span><\/span><\/span>Curation of gene-disease relationships in primary antibody deficiencies using the ClinGen validation framework. <span><em>J Allergy Clin Immunol<\/em> 16:S0091-6749(25)00016-8. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39826876\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Harlow*, OS, VR Ravi1*, F Ke, NL Sanders, E Armstrong, JP Mizgerd, AT Shenoy. 2024. The mysterious case of missing lymphocytes: a cautionary tale of inter-institutional variability in outcomes of lung dissociation protocols. <em>Am J Physiol: Lung Cell Mol Physiol <\/em>328:L260-L266. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39786964\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/span><\/span><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Yin, J, KM Hayes, MS Ong, JP Mizgerd, C Cunningham-Rundles, MI Dominguez, S Barmetter, J Farmer, PJ Maglione. 2024. Common variable immunodeficiency clinical manifestations are shaped by presence and type of heterozygous <em>NFKB1<\/em> variants. <em>J Allergy Clin Immunol Pract <\/em>(in press). <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39672378\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/span><\/span><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\"><span>Hiller, BE and JP Mizgerd. 2024. IFN-<\/span><span><a href=\"https:\/\/www.jci.org\/articles\/view\/185072\" target=\"_blank\" rel=\"noopener noreferrer\">g<\/a>amma<\/span><span> and YAP lead epithelial cells astray after severe respiratory infection<i>. J Clin Invest<\/i> 134:e185072. <a href=\"https:\/\/www.jci.org\/articles\/view\/185072\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><span><\/span><\/span><\/span><\/p>\n<p><span class=\"value ng-star-inserted\" id=\"author-0\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Crossey*, E, S<\/span><label class=\"mat-tooltip-trigger authors value ng-star-inserted\" id=\"SumAuthTa-DisplayName-author-en-0\" data-ta=\"SumAuthTa-DisplayName-author-en-0\" aria-describedby=\"cdk-describedby-message-mel-1-10\" cdk-describedby-host=\"mel-1\"><\/label><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-1\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Carty, S, FZ<\/span><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-2\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Shao, J <\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-3\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Henao-Vasquez, AB<\/span><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-4\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Ysasi, M<\/span><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-5\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Zeng, A<\/span><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-6\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Hinds, M<\/span><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-7\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Lo, A<\/span><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-8\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Tilston-Lunel, X<\/span><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-9\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Varelas, MR<\/span><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\" id=\"author-10\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Jones*, A<\/span><span dir=\"auto\" class=\"ng-star-inserted\">\u00a0<\/span><\/span><span class=\"value ng-star-inserted\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">Fine*<\/span><\/span><span class=\"value ng-star-inserted\"><span class=\"font-size-14 value ng-star-inserted\" lang=\"en\">. 2024. Influenza induces lung lymphangiogenesis independent of YAP\/TAZ activity in lymphatic endothelial cells. <em>Sci Rep<\/em> 14: <span>21324<\/span>. *co-corresponding authors. <a href=\"https:\/\/www.nature.com\/articles\/s41598-024-72115-6\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/span><\/p>\n<p><strong><\/strong>Ysasi, AB, AE Engler, PS Bawa, F Wang, AK Yeung, J Rock, JP Mizgerd, GJ Murphy. 2024. A specialized population of monocyte-derived tracheal macrophages promote airway epithelial regeneration through a CCR2-dependent mechanism. <em>iScience<\/em> 27(7):110169. <a href=\"https:\/\/www.cell.com\/iscience\/fulltext\/S2589-0042(24)01394-4\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/p>\n<p><span>Deshmukh, H, J Whitsett, W Zacharias, SS Way, FD Martinez, JP Mizgerd, G Pryhuber, N Ambalavanan, LB Bacharier, A Natarajan, R Tamburro, S Lin, A Randolph, G Nino, A Mejias, O Ramilo, and the NIH Workshop Participants of the Viral Lower Respiratory Tract Infections in Infancy and Early Childhood-Immunological and Developmental Aspects. 2024. Impact of viral lower respiratory tract infection (LRTI) in early childhood (0-2 years) on lung growth and development and lifelong trajectories of pulmonary health: a National Institutes of Health (NIH) Workshop Summary. <em>Pediatr Pulmonol <\/em>60:e27357. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39565217\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p><span>Auld*, SC, A Sheshadri*, J Alexander-Brett, Y Aschner, A Barczak, M Basil, K Cohen, C Dela Cruz, C McGroder, M Restrepo, K Ridge, L Schnapp, K Traber, R Wunderink, D Zhang, A Ziady, E Attia, J Carter, J Chalmers, K Crothers, C Feldman, B Jones, N Kaminski, J Keane, D Lewinsohn, M Metersky, JP Mizgerd, A Morris, J Ramirez, A Samarasinghe, B Staitieh, C Stek, J Sun, R van Zyl-Smit, SE Evans*. 2024. Post-infectious pulmonary complications: establishing research priorities to advance the field. <i>Ann Am Thorac Soc <\/i>21:1219-1237. *co-corresponding authors<\/span><\/p>\n<p><span>Lee, MM, Y Zuo, K Steiling, JP Mizgerd, B Kalesan, AJ Walkey. 2024. Clinical risk factors and blood protein biomarkers of 10-year pneumonia risk. <em>PLOS One<\/em> 19(7): e0296139. <a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0296139\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><em>\u00a0<\/em><\/span><\/p>\n<p><span>Faugno E, Galbraith AA, Walsh K, Maglione PJ, Farmer JR, Ong MS. 2024. <\/span>Experiences with diagnostic delay among underserved racial and ethnic patients: a systematic review of the qualitative literature. <span><em>BMJ Qual Saf<\/em> 4:bmjqs-2024-017506. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39496473\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p><span>Etesami, NS, KA Barker, AT Shenoy, C Lyon de Ana, EI Arafa, GN Grifno, AM Matschulat, ME Vannini, RMF Pihl, MP Breen, AM Soucy, WN Goltry, CT Ha, H Betsuyaku, JL Browning, X Varelas, KE Traber, MR Jones, LJ Quinton, PJ Maglione, HT Nia, AC Belkina,\u00a0 JP Mizgerd. 2024. B cells in the pneumococcus-infected lung are heterogeneous and require CD4<sup>+<\/sup> T cell help including CD40L to become resident memory B cells. <em>Front Immunol<\/em> 15:1382638. <a href=\"https:\/\/www.frontiersin.org\/journals\/immunology\/articles\/10.3389\/fimmu.2024.1382638\/full\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/p>\n<p><span>Ong MS, Rider NL, Stein S, Maglione PJ, Galbraith A, DiGiacomo DV, Farmer JR. 2024. <\/span>Racial and ethnic disparities in early mortality among patients with inborn errors of immunity. <span><em>J Allergy Clin Immunol<\/em> 153(1):335-340. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37802474\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p><span>Banerji R, G Grifno, L Shi, D Smolen, R LeBourdais, J Muhvich, C Eberman, B Hiller, J Lee, K Regan, SY Zheng, S Zhang, J Jiang, R Phil, K Traber, G Ligresti, JP Mizgerd, B Suki, HT Nia. 2023. Probing lung function at high spatiotemporal resolution using a novel crystal ribcage. <em>Nat Methods <\/em>20:1790-1801. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37710017\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p><span>Sullivan NP, Maniam N, Maglione PJ. 2023. Interstitial lung diseases in inborn errors of immunity. C<em>urr Opin Allergy Clin Immunol <\/em>23(6):500-506. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37823528\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p><span>Lyon De Ana, C, AT Shenoy, KA Barker, EI Arafa, NS Etesami, FT Korkmaz, AM Soucy, MP Breen, IMC Martin, BR Tilton, P Devarajan, NA Crossland, RM Pihl, WN Goltry, AC Belkina, MR Jones, LJ Quinton, JP Mizgerd. 2023. GL7 ligand expression defines a novel subset of CD4<sup>+<\/sup> T<sub>RM<\/sub> cells in lungs recovered from pneumococcus. <em>Mucosal Immunol <\/em>16:699-710. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1933021923000569?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/p>\n<p><span>Aihara F, Wang Y, Belkina AC, Fearns R, Mizgerd JP, Feng F, Kepler TB. 2023. Diversity of B cell populations and Ig repertoire in human lungs. <em>J Immunol<\/em> 11:486-496. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37314411\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p>Bintalib HM, van de Ven A, Jacob J, Davidsen JR, Fevang B, Hanitsch LG, Malphettes M, van Montfrans J, Maglione PJ, Milito C, Routes J, Warnatz K, Hurst JR. 2023. Diagnostic testing for interstitial lung disease in common variable immunodeficiency: a systematic review. <em>Front Immunol<\/em> 14:1190235. <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2023.1190235\/full\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/p>\n<p><span>Chen Y, Bharrhan S, Xu J, Sharma T, Wang Y, Salgame P, Zhang J, Nargan K, Steyn AJC, <\/span>Maglione PJ<span>, Chan J. 2023. B cells promote granulomatous inflammation during chronic Mycobacterium tuberculosis infection in mice. <em>PLoS Pathog <\/em>19(3):e1011187. <a href=\"https:\/\/journals.plos.org\/plospathogens\/article?id=10.1371\/journal.ppat.1011187\" target=\"_blank\" rel=\"noopener noreferrer\">Full text<\/a><\/span><\/p>\n<p><span lang=\"EN\">Center, DM, JP Mizgerd. 2023. In memoriam: Jerome S. 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Revised features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report. <em>Am J Respir Cell Mol Biol<\/em> 66:e1-e14. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35103557\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/p>\n<p><span>Paynich Murray, M, CM Crosby, P Marcovecchio, N Hartmann, S Chandra, M Zhao, A Khurana, S Zahner, BE Clausen, FT Coleman, JP Mizgerd, Z Mikulski, M Kronenberg. 2022. Stimulation of a subset of natural killer T cells by CD103+ DC is required for GM-CSF and protection from pneumococcal infection. <\/span><em>Cell Reports <\/em>38:110209. <a href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(21)01713-7\" target=\"_blank\" rel=\"noopener noreferrer\">full text<\/a><\/p>\n<p>Shenoy*, AT, C Lyon De Ana*, KA Barker, EI Arafa, IMC Martin, JP Mizgerd, AC Belkina. 2021. Comprehensive phenotyping of mouse lung resident lymphocytes after recovery from pneumococcal pneumonia. <em>Cytometry A<\/em> <span>101:892-902<\/span>. *co-first authors <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34854229\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/p>\n<p><span>Shenoy, AT, C Lyon De Ana, EI Arafa, I Salwig, KA Barker, FT Korkmaz, A Ramanujan, NS Etesami, AM Soucy, IMC Martin, BR Tilton, A Hinds, WN Goltry, H Kathuria, T Braun, MR Jones, LJ Quinton, AC Belkina, JP Mizgerd. 2021. Antigen presentation by lung epithelial cells directs CD4<sup>+<\/sup> T<sub>RM <\/sub>cell function and regulates barrier immunity. <em>Nat Commun <\/em>12:5834. <a href=\"https:\/\/rdcu.be\/cySuT\" target=\"_blank\" rel=\"noopener noreferrer\">full text<\/a><\/span><\/p>\n<p><span>Odom, CV, Y Kim, CL Burgess, LA Baird, FT Korkmaz, E Na, AT Shenoy, EI Arafa, TT Lam, MR Jones, JP Mizgerd, KE Traber, LJ Quinton. 2021. Liver-dependent lung remodeling in the wake of systemic inflammation shapes responses to secondary infection. <em>J Immunol <\/em>207:1891-1902. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34470857\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p><span>Abyazi, ML, KA Bell, G Gyimesi, TS Baker, M Byun, HM Ko, C Cunningham-Rundles, F Feng, PJ Maglione. 2021. Convergence of cytokine dysregulation and antibody deficiency in common variable immunodeficiency with inflammatory complications. <i>J Allergy Clin Immunol<\/i><span class=\"Apple-converted-space\"> 149:315-326. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34146579\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/span><\/p>\n<p><span>Dela Cruz*, CS, SE Evans*, MI Restrepo, N Dean, A Torres, I Amara-Elori, S Awasthi, E Caler, B Cao, JD Chalmers, J Chastre, TS Cohen, AH Cohen, K Crothers, YP Di, ME Egan, C Feldman, S Gautam, ES Halstead, S Herold, BE Jones, C Luna, MS Niederman, R Mendez, R Menendez, JP Mizgerd, R Nusrat, J Ramirez, Y Shindo, C Stevens, G Waterer, SM Yeligar, RG Wunderink*. 2021. Understanding the host in the management of pneumonia: an official ATS workshop report. <em>Ann Am Thorac Soc <\/em>18:1087-97. *co-corresponding authors <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34242148\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><span class=\"Apple-converted-space\"><\/span><\/p>\n<p><span>Keefe, J, C Yao, SJ Hwang, P Courchesne, GY Lee, J Dupuis, JP Mizgerd, G O\u2019Connor, GR Washko, MH Cho, EK Silverman, D Levy. 2021. An Integrative Genomic Strategy Identifies sRAGE as a Causal and Protective Biomarker of Lung Function. <em>CHEST <\/em>161:76-84.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34237330\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p><span>Barker, KA, NS Etesami, AT Shenoy, EI Arafa, C Lyon de Ana,<sup> <\/sup>NMS Smith, IMC Martin, WN Goltry, AMS Barron, JL Browning, H Kathuria, AC Belkina, A Guillon, X Zhong, NA Crossland, MR Jones, LJ Quinton, JP Mizgerd. 2021. 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Recent endemic coronavirus infection is associated with less severe COVID-19. \u00a0<em>J Clin Invest<\/em> <span>131:e143380<\/span><span><\/span>. *co-corresponding authors <a href=\"https:\/\/www.jci.org\/articles\/view\/143380\" target=\"_blank\" rel=\"noopener noreferrer\">full text<\/a><\/p>\n<p><span>Guillon, A, JP Mizgerd, L Grammatico-Guillon. 2020. Two-year survival among elderly hospitalized for acute respiratory infection versus hip fracture: a useful comparison to raise awareness. <i>Eur Respir Rev <\/i>29(158):200156. <a href=\"https:\/\/err.ersjournals.com\/content\/29\/158\/200156.long\" target=\"_blank\" rel=\"noopener noreferrer\">full text<\/a><\/span><span><\/span><\/p>\n<p>Semler, MW, GR Bernard, SD Aaron, DC Angus, MH Biros, RG Brower, CS Calfee, EA Colantuoni, ND Ferguson, MN Gong, RO Hopkins, CL Hough, TJ Iwashyna, BD Levy, TR Martin, MA Matthay, JP Mizgerd, M Moss, DM Needham, WH Self, CW Seymour, RD Stapleton, BT Thompson, RG Wunderink, M Proschan, NR Aggarwal, LA Reineck. 2020. 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Integrative physiology of pneumonia. <em>Physiol Rev<\/em>\u00a0<span>98:1417-1464. <a href=\"\/pneumonia\/files\/2018\/08\/physrev.00032.2017.pdf\">full text<\/a><\/span><\/p>\n<p>Quinton, LJ. 2018. C-rac-king the code of smoke-induced pneumonia susceptibility. <em>Am J Respir Crit Care Med<\/em> 198:1246-1248. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30063845\">PubMed<\/a><span>\u00a0<\/span><\/p>\n<p>Smith, NMS, GA Wasserman, FT Coleman, KL Hilliard, K Yamamoto, E Lipsitz, R Malley, H Dooms, MR Jones, LJ Quinton, JP Mizgerd. 2018. Regionally compartmentalized resident memory T cells mediate naturally acquired protection against pneumococcal pneumonia. <em>Mucosal Immunol<\/em> 11:220-235. <a href=\"http:\/\/rdcu.be\/r3KR\">full text<\/a><\/p>\n<p>Dela Cruz*, CS, RG Wunderink*, DC Christiani, SA Cormier, K Crothers, CM Doerschuk, SE Evans, DR Goldstein, P Khatri, L Kobzik, JK Kolls, BD Levy, ML Metersky, MS Niederman, R Nusrat, CJ Orihuela, P Peyrani, AS Prince, JA Ram\u00edrez, KM Ridge, S Sethi, BT Suratt, JI Sznajder, EL Tsalik, AJ Walkey, S Yende, NR Aggarwal, EV Caler, JP Mizgerd*. 2018. Future research directions in pneumonia: NHLBI working group report. <em>Am J Respir Crit Care Med<\/em>\u00a0<span>198:256-263<\/span>.\u00a0*co-corresponding authors\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29546996\">PubMed<\/a><\/p>\n<p>Filion, CA, S Taylor-Black, PJ Maglione, L Radigan, C Cunningham-Rundles. 2018. Differentiation of Common Variable Immunodeficiency from IgG Deficiency. <i>J Allergy Clin Immunol Pract<\/i>\u00a07:1277-1284.<span class=\"Apple-converted-space\">\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30557717\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p><span>Mizgerd, JP, HJ Zar. 2018. Global Burden of Respiratory Infections and Mucosal Immunology of the Respiratory Tract. In <i>Rudolph\u2019s Pediatrics<\/i>, 23<sup>rd<\/sup> edition, edited by MW Kline, SM Blaney, AP Giardino, JS Orange, DJ Penny, GE Schutze, LS Shekerdemian, AM Rudolph, CD Rudolph, McGraw Hill (United States). <a href=\"https:\/\/accesspediatrics.mhmedical.com\/book.aspx?bookid=2126\" target=\"_blank\" rel=\"noopener noreferrer\">Book<\/a><\/span><span><\/span><\/p>\n<p>Romberg, N, C Le Coz, S Glauzy, JN Schickel, M Trofa, BE Nolan, M Paessler, M LuQing Xu, M Lambert, SA Lakhani, MK Khokha, S Jyonouchi, J Heimall, P Takach, PJ Maglione, J Catanzaro, FI Hsu, KE Sullivan, C Cunningham-Rundles, E Meffre. 2018. CVID patients with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responses. <i>J Allergy Clin Immunol<\/i> <span>143:258-265<\/span>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29935219\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p>Hartmann, N, C McMurtrey, ML Sorensen, ME Huber, R Kurapova, FT Coleman, JP Mizgerd, W Hildebrand, M Kronenberg, DM Lewinsohn, MJ Harriff. 2017. Riboflavin metabolism variation among clinical isolates of <em>Streptococcus pneumoniae<\/em> results in differential activation of MAIT cells. <em>Am J Respir Cell Mol Biol<\/em> 58:757-776. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29356555\">PubMed<\/a><\/p>\n<p><span>Wasserman, GA, A Szymaniak, AC Hinds, K Yamamoto, H Kamata, NMS Smith, KL Hilliard, C Carrieri, AT Labadorf, LJ Quinton, X Ai, X Varelas, JP Mizgerd, A Fine, D O\u2019Carroll, MR Jones. 2017. A discrete population of multiciliated epithelial cells expresses MIWI2 to regulate airway cell composition and pulmonary inflammation. <em>J Clin Invest <\/em>127:3866-3876. <a href=\"https:\/\/www.jci.org\/articles\/view\/94639\" target=\"_blank\" rel=\"noopener noreferrer\">full text<\/a><\/span><\/p>\n<p><span>Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, Traber K,\u00a0<\/span>Quinton LJ<span>, Crane A, Davis BR, White FV, Wambach J, Whitsett JA, Cole FS, Morrisey EE, Guttentag SH, Beers MF, Kotton DN. 2017. Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.\u00a0<em>Cell Stem Cell<\/em>\u00a021:472-488. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28965766\">PubMed<\/a><\/span><\/p>\n<p>Willinger, CM, J Rong, K Tanriverdi, PL Courchesne, T Huan, GA Wasserman, H Lin, J Dupuis, R Joehanes, MR Jones, G Chen, EJ Benjamin, GT O\u2019Connor, JP Mizgerd, JE Freedman, MG Larson, D Levy. 2017. A microRNA signature of cigarette smoking and evidence for a causal role of microRNAs in smoking-related inflammation and target organ damage.\u00a0 <em>Circ Cardiovasc Genet <\/em>10:e001678. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29030400\">PubMed<\/a><\/p>\n<p><span>Traber KE, Symer EM, Allen E, Kim Y, Hilliard KL, Wasserman GA, Stewart CL, Jones MR, <\/span>Mizgerd<span> JP, Quinton LJ. 2017.\u00a0<\/span>Myeloid-epithelial crosstalk coordinates synthesis of the tissue protective cytokine leukemia inhibitory factor during pneumonia. <em>Am J Physiol: Lung Cell Mol Physiol<\/em>\u00a0313:L548-L558. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28522567\">PubMed<\/a><\/p>\n<p>Coleman, FT, MT Blahna, H Kamata, K Yamamoto, MC Zabinski, I Kramnik, AA Wilson, DN Kotton, LJ Quinton, MR Jones, SI Pelton, JP Mizgerd. 2017. The capacity of pneumococci to activate macrophage NF-\u03baB determines necroptosis and pneumonia severity. <em>J Infect Dis<\/em>\u00a0216:425-435. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28368460\">PubMed<\/a>\u00a0&#8211; with Cover Photo from Dr. Fadie Coleman!<\/p>\n<p>Guti\u00e9rrez-V\u00e1zquez, C, AJ Enright, A Rodr\u00edguez-Gal\u00e1n, A Perez-Garc\u00eda, P Collier, MR Jones, V Benes, JP Mizgerd, M Mittelbrunn, AR Ramiro, and F S\u00e1nchez-Madrid. 2017. 3&#8217;uridylation controls mature microRNA turnover during CD4 T cell activation. <em>RNA <\/em>23:882-891. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28351886\">PubMed<\/a><\/p>\n<p>Kasotakis, G, MD Galvan, P Osathanugrah, N Dharia, L Bufe, Z Breed, D Mabarak, N Singh, JP Mizgerd, E Kintsurashvili, D Remick. 2017. Timing of administration of valproic acid in the treatment of acute respiratory distress syndrome: prevention is the best therapy? <em>J Surg Res<\/em> 220:206-212. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29180183\">PubMed<\/a><\/p>\n<p>Kasotakis G, M Galvan, E King, B Sarkar, A Stucchi, JP Mizgerd, PA Burke, D Remick. 2017. Valproic acid mitigates the inflammatory response and prevents acute respiratory distress syndrome in a murine model of <em>Escherichia coli<\/em> pneumonia at the expense of bacterial clearance. <em>J Trauma Acute Care Surg<\/em>\u00a0<span>82:758-765<\/span>. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28368460\">PubMed<\/a><\/p>\n<p>EA Stanford, A Ramirez-Cardenas, Z Wang, O Novikov, P Koutrakis, JP Mizgerd, CA Genco, MA Kukuruzinska, S Monti, MV Bais, DH Sherr. 2016. The aryl hydrocarbon receptor mediates oral squamous cell carcinoma invasion. Mol Cancer Res 14:696-706. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27130942\">PubMed<\/a><\/p>\n<p>Kamata, H, K Yamamoto, GA Wasserman, M Zabinski, C Yuen, W Lung, A Gower, AC Belkina, MI Ramirez, JC Deng, LJ Quinton, MR Jones, JP Mizgerd. 2016. Epithelial cell-derived secreted and transmembrane 1a (Sectm1a) signals to activated neutrophils during pneumococcal pneumonia. <em>Am J Respir Cell Mol Biol<\/em> 55:407-418.<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27064756\">PubMed<\/a><\/p>\n<p>Mizgerd, JP. 2015. Community-acquired pneumonia requiring hospitalization. <em>N Engl J Med<\/em> 373:2380. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26650160\">PubMed<\/a><\/p>\n<p>Hilliard, KL, E Allen, KE Traber, Y Kim, MR Jones, JP Mizgerd, LJ Quinton. 2015. Activation of hepatic STAT3 maintains pulmonary defense during endotoxemia. <em>Infect Immun<\/em> 83:4015-27. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26216424\">PubMed<\/a><\/p>\n<p>Traber, KE, KL Hilliard, E Allen, GA Wasserman, K Yamamoto, MR Jones, JP Mizgerd, LJ Quinton. 2015. Oncostatin M induces STAT3-dependent CXCL5 expression and neutrophil recruitment during pneumonia. <em>Am J Respir Cell Mol Biol<\/em> 53:479-88. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25692402\">PubMed<\/a><\/p>\n<p>Quinton, LJ, JP Mizgerd. 2015. Dynamics of lung defense in pneumonia: resistance, resilience, and remodeling. <em>Annu Rev Physiol<\/em> 77:407-30. <a href=\"http:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-physiol-021014-071937\">Journal<\/a><\/p>\n<p>Cols, M, A Rahman, PJ Maglione, Y Garcia-Carmona, N Simchoni, HM Ko, L Radigan, A Ceurtti, D Blankenship, V Pascual, C Cunningham-Rundles. 2015. Expansion of inflammatory innate lymphoid cells in patients with common variable immune deficiency. <i>J Allergy Clin Immunol<\/i>\u00a0137: 1206-1215.<span class=\"Apple-converted-space\">\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26542033\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p>Hilliard, KL, E Allen, KE Traber, K Yamamoto, NM Stauffer, GA Wasserman, MR Jones, JP Mizgerd, LJ Quinton. 2015. The lung-liver axis facilitates pulmonary innate immunity and hepatoprotection during pneumonia. <em>Am J Respir Cell Mol Biol<\/em> 53:378-90. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25607543\">PubMed<\/a><\/p>\n<p>Stein, CR, KJ McGovern, AM Pajak, PJ Maglione, MS Wolff. 2015. Perfluoroalkyl and polyfluoroalkyl substances and indicators of immune function in children aged 12-19 y: National Health and Nutrition Examination Survey. <i>Pediatr Res<\/i>\u00a079: 348-357.<span class=\"Apple-converted-space\">\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26492286\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p>Maglione, PJ, JR Overbey, C Cunningham-Rundles. 2015. Progression of CVID interstitial lung disease accompanies distinct pulmonary and laboratory findings. <i>J Allergy Clin Immunol Pract\u00a0<\/i>3: 941-50.<span class=\"Apple-converted-space\">\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26372540\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p>Mizgerd JP. 2014. The infant nose: Introducing the respiratory tract to the world. <em>Am J Respir Crit Care Med<\/em> 190:1206-7. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25436779\">PubMed<\/a><\/p>\n<p>Hyatt LD, Wasserman GA, Rah YJ, Matsuura KY, Coleman FT, Hilliard KL, Pepper-Cunningham ZA, Ieong M, Stumpo DJ, Blackshear PJ, Quinton LJ, Mizgerd JP, Jones MR. 2014. Myeloid ZFP36L1 does not regulate inflammation or host defense in mouse models of acute bacterial infection. <em>PLoS ONE<\/em> 9(10): e109072. <a href=\"http:\/\/www.plosone.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pone.0109072\">Full Text<\/a><\/p>\n<p>Ubags ND, Vernooy JH, Burg E, Hayes C, Bement J, Dilli E, Zabeau L, Abraham E, Poch KR, Nick JA, Dienz O, Zu\u00f1iga J, Wargo MJ, Mizgerd JP, Tavernier J, Rinc\u00f3n M, Poynter ME, Wouters EFM, Suratt BT. 2014. The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury. <em>Crit Care Med<\/em> 42:e143-51. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24231757\">PubMed<\/a><\/p>\n<p>Yamamoto K, Ahyi AN, Pepper-Cunningham ZC, Ferrari JD, Wilson AA, Jones MR, Quinton LJ, Mizgerd JP. 2014. Roles of lung epithelium in neutrophil recruitment during pneumococcal pneumonia. <em>Am J Respir Cell Mol Biol<\/em> 50:253-262. <a href=\"http:\/\/www.atsjournals.org\/doi\/abs\/10.1165\/rcmb.2013-0114OC#.Uu7JbXkob1o\">Journal<\/a><\/p>\n<p>Maglione, PJ, N Simchoni, S Black, L Radigan, JR Overbey, E Bagiella, JB Bussel, X Bossuyt, J-L Casanova, I Meyts, A Cerutti, C Picard, C Cunningham-Rundles. 2014. IRAK- and MyD88- deficiencies impair IgM responses against T-independent bacterial antigens in humans. <i>Blood<\/i>. 124: 3561-3571.<span class=\"Apple-converted-space\">\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25320238\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p>Ahyi AN, Quinton LJ, Jones MR, Ferrari JD, Pepper-Cunningham ZA, Mella JR, Remick DG, Mizgerd JP. 2013. STAT3 participates in the hepatic unfolded protein response to enhance secretion of acute phase proteins during pneumonia. <em>Infect Immun<\/em> 1644-53. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23460517\">PubMed<\/a><\/p>\n<p>Zhang H, Neuh\u00f6fer P, Song L, Rabe B, Lesina M, Kurkowski MU, Treiber M, Wartmann T, Regn\u00e9r S, Thorlacius H, Saur D, Weirich G, Yoshimura A, Halangk W, Mizgerd JP, Schmid RM, Rose-John S, Alg\u00fcl H. 2013. IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality. <em>J Clin Invest<\/em> 123:1019-31. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23426178\">PubMed<\/a><\/p>\n<p>Maglione, PJ, JR Overbey, L Radigan, E Bagiella, C Cunningham-Rundles. 2014. Pulmonary radiologic findings in CVID: clinical and immunological correlations. <i>Ann Allergy Asthma Immunol<\/i>\u00a0113: 452-459.<span class=\"Apple-converted-space\">\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24880814\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p>Wilson AA, Kwok LW, Porter EL, Payne JG, Ohle SJ, Greenhill SR, Blahna MT, Yamamoto K, Jean JC, Mizgerd JP, Kotton DN. 2013. Lentiviral delivery of RNAi for in vivo lineage specific modulation of gene expression in mouse lung macrophages. <em>Mol Ther<\/em> 21:825-33. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23403494\">PubMed<\/a><\/p>\n<p>Maglione, PJ, HM Ko, MB Beasley, JA Strauchen, C Cunningham-Rundles. 2013. Tertiary lymphoid neogenesis is a component of pulmonary lymphoid hyperplasia in CVID. <i>J Allergy Clin Immunol<\/i>\u00a0133: 535-542.<span class=\"Apple-converted-space\">\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24131823\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p>Stanya KJ, Jacobi D, Liu S, Bhargava P, Dai L, Gangl MR, Inouye K, Barlow JL, Ji Y, Mizgerd JP, Qi L, Shi H, McKenzie ANJ, Lee CH. 2013. Direct control of hepatic glucose production by interleukin-13. <em>J Clin Invest<\/em> 123:261-271. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23257358\">PubMed<\/a><\/p>\n<p>Bartlett NW, Slater L, Glanville N, Haas JJ, Caramori G, Casolari P, Clarke DL, Message SD, Anisenko J, Kebadze T, Mallia P, Mizgerd JP, Belvisi M, Papi A, Kotenko SV, Johnston SL, Edwards MR. 2012. Defining critical roles for NF-\u03baB p65 and type I interferon in innate immunity to rhinovirus. <em>EMBO Mol Med<\/em> 4:1244-1260. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23165884\">PubMed<\/a><\/p>\n<p>Jones* MR, Blahna* MT, Kozlowski E, Matsuura KY, Ferrari JD, Morris SA, Powers JT, Daley GQ, Quinton LJ, Mizgerd JP. 2012. Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival. <em>PLOS Genet<\/em> 8(11): e1003105. *co-first authors\u00a0<a href=\"http:\/\/www.plosgenetics.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pgen.1003105\">Full text<\/a><\/p>\n<p>Quinton LJ. 2012. Evaluating the NET influence of inflammation on pneumonia biology. <em>Am J Respir Crit Care Med<\/em> 186:943-944. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23155213\">PubMed<\/a><\/p>\n<p>Yamamoto K, Ferrari JD, Cao YX, Ramirez MI, Jones MR, Quinton LJ, Mizgerd JP. 2012. Type I alveolar epithelial cells mount innate immune responses during pneumococcal pneumonia. <em>J Immunol<\/em> 189:2450-2459. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22844121\">PubMed<\/a><\/p>\n<p>Mizgerd JP. 2012. Respiratory infection and the impact of pulmonary immunity on lung health and disease. <em>Am J Respir Crit Care Med<\/em> 186:824-829. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22798317\">PubMed<\/a><\/p>\n<p>Quinton LJ, Mizgerd JP, Hilliard KL, Jones MR, Kwon CY, Allen E. 2012. Leukemia inhibitory factor signaling is required for lung protection during pneumonia. <em>J Immunol<\/em> 188:6300-6308. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22581855\">PubMed<\/a><\/p>\n<p>Quinton* LJ, MT Blahna, MR. Jones, E Allen, JD Ferrari, KL Hilliard, X Zhang, V Sabharwal, H Alg\u00fcl, S Akira, RM Schmid, SI Pelton, A Spira, JP Mizgerd*. 2012. Hepatocyte-specific mutation of both NF-kappaB RelA and STAT3 abrogates the acute phase response in mice. <em>J Clin Invest<\/em> 122:1758-1763. *co-corresponding authors\u00a0<a href=\"http:\/\/www.jci.org\/articles\/view\/59408\">Full Text<\/a><\/p>\n<p><span>Quinton, LJ, JP Mizgerd. 2012. Transcriptional Signaling Hubs in Epithelial Cells During Pneumonia. In <i>Mucosal Immunology of Acute Bacterial Pneumonia<\/i>, edited by AS Prince. Springer: New York, NY. <a href=\"https:\/\/www.springer.com\/gp\/book\/9781461453253\" target=\"_blank\" rel=\"noopener noreferrer\">Book<\/a><\/span><span><\/span><\/p>\n<p>Blahna MT, Jones MR, Quinton LJ, Matsuura KY, Mizgerd JP. 2011. Terminal uridyltransferase enzyme Zcchc11 promotes cell proliferation independent of its uridyltransferase activity. <em>J Biol Chem<\/em> 286:42381-42389. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22006926\">PubMed<\/a><\/p>\n<p>Pittet LA, Quinton LJ, Yamamoto K, Robson BE, Ferrari JD, Algul H, Schmid RM, Mizgerd JP. 2011. Earliest innate immune responses require macrophage RelA during pneumococal pneumonia. <em>Am J Respir Cell Mol Biol<\/em> 45:573-581. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21216972\">PubMed<\/a><\/p>\n<p>Quinton LJ,\u00a0Mizgerd JP. 2011. NF-kB and STAT3 signaling hubs for lung innate immunity. <em>Cell Tissue Res<\/em> 343:153-165. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20872151\">PubMed<\/a><\/p>\n<p><span>Kolls, JK, JP Mizgerd. 2011. Global Burden of Respiratory Infections and Mucosal Immunology of the Respiratory Tract. In <i>Rudolph\u2019s Pediatrics<\/i>, 22<sup>nd<\/sup> edition, edited by CD Rudolph, AM Rudolph, GE Lister, LR First, AA Gershon. McGraw Hill (United States). <a href=\"https:\/\/www.amazon.com\/Rudolphs-Pediatrics-22nd-Author-Rudolph-dp-B00XV48GIU\/dp\/B00XV48GIU\/ref=mt_other?_encoding=UTF8&amp;me=&amp;qid=\" target=\"_blank\" rel=\"noopener noreferrer\">Book<\/a><\/span><span><\/span><\/p>\n<p>Perrone LA,\u00a0Szretter KJ,\u00a0Katz JM,\u00a0Mizgerd JP,\u00a0Tumpey TM. 2010. Mice lacking both TNF and IL-1 receptors exhibit reduced lung inflammation and delay in onset of death following infection with a highly virulent H5N1 virus. <em>J Infect Dis<\/em> 202:1161-70. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20815704\">PubMed<\/a><\/p>\n<p>Jones MR, Quinton LJ, Blahna MT, Neilson JR, Fu S, Ivanov AR, Wolf DA, Mizgerd JP. 2009. Zcchc11-dependent uridylation of microRNA directs cytokine expression. <em>Nature Cell Biol.<\/em> 11:1157-1163. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19701194?ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p>Quinton LJ, Jones MR, Robson BE, Mizgerd JP. 2009. Mechanisms of the hepatic acute phase response during bacterial pneumonia. <em>Infect. Immun.<\/em> 77: 2417-26. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19289507?ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p>Gamble L, Bagby GJ, Quinton LJ, Happel KI, Mizgerd JP, Zhang P, Nelson S. 2009. The systemic and pulmonary lipopolysaccharide binding protein response to intratracheal lipopolysaccharide. <em>Shock<\/em> 31: 212-7. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18359888?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p>Li Y, Jia Y, Pichavant M, Loison F, Sarraj B, Kasorn A, You J, Robson BE, Umetsu DT, Mizgerd JP, Ye K, Luo HR. 2009. Targeted deletion of tumor suppressor PTENaugments neutrophil function and enhances host defense in neutropenia-associated pneumonia. <em>Blood<\/em> 113:4930-41. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19286998?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p>Lang JE, Williams ES, Mizgerd JP, Shore SA. 2008. Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6. <em>Am J Physiol Lung Cell Mol Physiol<\/em> 294:L1013-20. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18359888?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p>Quinton, LJ, MR Jones, BE Robson, BT Simms, JA Whitsett, JP Mizgerd. 2008. Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during <em>Escherichia coli<\/em> pneumonia. <em>Am. J. Respir. Cell Mol. Biol.<\/em> 38:699-706. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18192501?ordinalpos=4&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p>Mizgerd, JP. 2008. Acute lower respiratory infection. <em>N. Engl. J. Med.<\/em> 14:716-27. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/nejmalri.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, SJ Skerrett. 2008. Animal models of human pneumonia. <em>Am. J. Physiol.: Lung Cell. Mol. Biol.<\/em> 294:L387-98.<a href=\"http:\/\/ajplung.physiology.org\/cgi\/content\/full\/00330.2007?ijkey=coz\/AZC.IXPDk&amp;keytype=ref&amp;siteid=physiology\">pdf<\/a><\/p>\n<p>Maglione, PJ, J Xu, A Casadevall, J Chan. 2008. Fc\u03b3 receptors regulate immune activation and susceptibility during <i>Mycobacterium tuberculosis i<\/i>nfection. <i>J. Immunol. <\/i>180: 3329:3338. Highlighted article: In This Issue. <i>J Immunol\u00a0<\/i>180: 2721-2722.<span class=\"Apple-converted-space\">\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18292558\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p>Huang Y, Zhang J, McHenry KT, Kim MM, Zeng W, Lopez-Pajares V, Dibble CC, Mizgerd JP, Yuan ZM. 2008.\u00a0Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation. <em>Cancer Res<\/em> 68:9131-6. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19010883?ordinalpos=3&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p>Subramanian, KK, Jia Y, Zhu D, Simms BT, Jo H, Hattori H, You J, Mizgerd JP, Luo HR. 2007. Tumor suppressor PTEN is a physiological suppressor of chemoattractant-mediated neutrophil functions. <em>Blood<\/em> 109:4028-4037.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?Db=pubmed&amp;Cmd=ShowDetailView&amp;TermToSearch=17202315&amp;ordinalpos=4&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p><span>Traber, KE, E Lee, S Benson, R Corrigan, M Cantera, B Shopsin, RP Novick. 2008. <em>agr<\/em> funtion in clinical <em>Staphylococus aureus<\/em> isolates. <em>Microbiol<\/em> 154:2265-74. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18667559\">PubMed<\/a><\/span><\/p>\n<p>Nakahira, M, T Tanaka, BE Robson, JP Mizgerd, MJ Grusby. 2007. Regulation of STAT signaling by the tyrosine phosphatase PTP-BL. <em>Immunity<\/em> 26:163-176.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?Db=pubmed&amp;Cmd=ShowDetailView&amp;TermToSearch=17306571&amp;ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p>Quinton, LJ, MR Jones, BT Simms, MS Kogan, BE Robson, SJ Skerrett, JP Mizgerd. 2007. Functions and regulation of NF-?B RelA during pneumococcal pneumonia. <em>J. Immunol.<\/em> 178:1896-1903.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?db=pubmed&amp;cmd=Retrieve&amp;dopt=AbstractPlus&amp;list_uids=17237440&amp;query_hl=11&amp;itool=pubmed_docsum\">PubMed<\/a><\/p>\n<p>Maglione, PJ, J Xu, J Chan. 2007. B cells moderate inflammatory progression and enhance bacterial containment upon pulmonary challenge with <i>Mycobacterium tuberculosis<\/i>. <i>J Immunol\u00a0<\/i>178: 7222-7234.<span class=\"Apple-converted-space\">\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17513771\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/span><\/p>\n<p>Johnston, RA, Mizgerd JP, Flynt L, Quinton LJ, Williams ES, Shore SA. 2007. Type I interleukin-1 receptor is required for pulmonary responses to subacute ozone exposure in mice. <em>Am J Respir Cell Mol Biol<\/em> 37:477-484.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?Db=pubmed&amp;Cmd=ShowDetailView&amp;TermToSearch=17575079&amp;ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\">PubMed<\/a><\/p>\n<p><span>Happel, KI, Rudner, X, Quinton, LJ, Movassaghi, JL, Clark, C, Odden, AR, Zhang, P, Bagby, GJ, Nelson, S, Shellito, JE 2007. Acute alcohol intoxication suppresses the pulmonary ELR-negative CXC chemokine response to lipopolysaccharide. <em>Alcohol<\/em> 41: 325-333 <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17889309?ordinalpos=4&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/p>\n<p>Prince, AS, JP Mizgerd, J Wiener-Kronish, J Bhattacharya. 2006. Cell signaling underlying the pathophysiology of pneumonia. <em>Am. J. Physiol.: Lung Cell. Mol. Biol.<\/em> 291:L297-300. <a href=\"http:\/\/ajplung.physiology.org\/cgi\/content\/full\/291\/3\/L297\">Full text<\/a><\/p>\n<p>Yano, K, PC Liaw, JM Mullington, SC Shih, H Okada, N Bodyak, PM Kang, L Toltl, B Belikoff, J Buras, BT Simms, JP Mizgerd, P Carmeliet, SA Karumanchi, WC Aird. 2006. Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality. <em>J. Exp. Med.<\/em> 203:1447-1458. <a href=\"http:\/\/www.jem.org\/cgi\/content\/full\/203\/6\/1447\">Full text<\/a><\/p>\n<p>Krishnamurthy, VM, LJ Quinton, LA Estroff, SJ Metallo, JM Isaacs, JP Mizgerd, GM Whitesides. 2006. Promotion of opsonization by antibodies and phagocytosis of Gram-positive bacteria by a bifunctional polyacrylamide. <em>Biomaterials<\/em> 27:3663-3674. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16527349&amp;query_hl=2&amp;itool=pubmed_docsum\">PubMed<\/a><\/p>\n<p>Mizgerd, JP. 2006. Lung infection- A public health priority. <em>PLoS Medicine<\/em> 3:e76. <a href=\"http:\/\/medicine.plosjournals.org\/archive\/1549-1676\/3\/2\/pdf\/10.1371_journal.pmed.0030076-p-L.pdf\">pdf<\/a><\/p>\n<p>Jones, MR, LJ Quinton, BT Simms, MM Lupa, MS Kogan, JP Mizgerd. 2006. Roles of interleukin-6 in STAT activation and neutrophil recruitment during <em>Escherichia coli<\/em> pneumonia. <em>J. Infect. Dis.<\/em> 193:360-369. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16388483&amp;query_hl=1&amp;itool=pubmed_docsum\">PubMed<\/a><\/p>\n<p>Traber K<span>, Novick R. 2006. A slipped-mispairing mutation in AgrA of laboratory strains and clinical isolates results in delayed activation of agr and failure to translate delta- and alpha-hemolysins. <em>Mol Microbiol<\/em> 59:1519-30. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16468992\">PubMed<\/a><\/span><\/p>\n<p>Mizgerd, JP. 2005. Transcription Factors: Nuclear Factor-?B and Inhibitory Protein ?B. In <em><a href=\"http:\/\/www.sciencedirect.com\/science\/referenceworks\/9780123708793\">Encyclopedia of Respiratory Medicine<\/a><\/em>, edited by GJ Laurent and SD Shapiro. Elsevier Limited: Oxford, UK, pp. 265-269.<\/p>\n<p>Jones, MR, BT Simms, MM Lupa, MS Kogan, JP Mizgerd. 2005. Lung NF-?B activation and neutrophil recruitment require IL-1 and TNF receptor signaling during pneumococcal pneumonia. <em>J. Immunol.<\/em> 175:7530-7535. <a href=\"http:\/\/www.jimmunol.org\/cgi\/content\/full\/175\/11\/7530\">Full text<\/a><\/p>\n<p>Mizgerd, JP. 2005. Mac-1 mediates migration to lymph nodes. <em>Blood<\/em> 109:2927-2928. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/mac1-blood.pdf\">pdf<\/a><\/p>\n<p>Faffe, DS, L Flynt, M Mellema, PE Moore, ES Silverman, V Subramaniam, MR Jones, JP Mizgerd, T Whitehead, A Imrich, RA Panettieri, Jr, SA Shore. 2005. Oncostatin M causes eotaxin release from airway smooth muscle: synergy with IL-4 and IL-13. <em>J. Allergy Clin. Immunol.<\/em> 115:514-520. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=15753898&amp;query_hl=1\">PubMed<\/a><\/p>\n<p>Johnston, R.A., J.P. Mizgerd, S.A. Shore. 2005. CXCR2 is essential for maximal neutrophil recruitment and methacholine responsiveness after ozone exposure. <em>Am. J. Physiol.: Lung Cell. Mol. Biol.<\/em> 288:L61-L67. <a href=\"http:\/\/ajplung.physiology.org\/cgi\/content\/full\/288\/1\/L61\">Full text<\/a><\/p>\n<p><span>Quinton, LJ, Nelson, S, Zhang, P, <\/span><span>Happel, KI, Gamble, L, Bagby, GJ. 2005. Effects of systemic and local CXC chemokine administration on the ethanol-induced suppression of pulmonary neutrophil recruitment. <em>Alcohol: Clin. Exp. Res.<\/em> 29: 1198-1205. <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16046875?ordinalpos=10&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/p>\n<p><span>Zhang, P, Quinton, LJ, Gamble, L, Bagby, GJ, Summer, WR, Nelson, S 2005. The granulopoietic cytokine response and enhancement of granulopoiesis in mice during endotoxemia. <em>Shock<\/em>. 23: 344-352. <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15803058?ordinalpos=12&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/p>\n<p><span>Happel, KI, Dubin, PJ, Zheng, M, Quinton, LJ, Odden, AR, Shellito, JE, Bagby, GJ, Nelson, S, Kolls, JK 2005. Divergent roles of IL-12 and IL-23 in host defense against Klebsiella pneumoniae. <em>J. Exp. Med<\/em>. 202: 761-769 <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16157683?ordinalpos=9&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/p>\n<p><span>Badewa, AP, Quinton, LJ, Shellito, JE, Mason, CM 2005. Chemokine receptor 5 and its ligands in the immune response to murine tuberculosis. <em>Tuberculosis<\/em>. 85 185-195. <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15850756?ordinalpos=11&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/p>\n<p><span>Poonia, B, Nelson, S, Bagby, GJ, Zhang, P, Quinton, LJ, Veazey, RS. 2005. Chronic alcohol consumption results in higher simian immunodeficiency virus replication in mucosally inoculated rhesus macaques. <em>AIDS Res Hum Retroviruses<\/em>. 21:863-868. <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16796534?ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus\">Pubmed<\/a><\/p>\n<p><span>Shahbazian, LM, Quinton, LJ, Bagby, GJ, Nelson, S, Wang, G, and Zhang, P. 2004.\u00a0<em>Escherichia coli<\/em> pneumonia enhances granulopoiesis and the mobilization of myeloid progenitor cells into the systemic circulation. <em>Crit. Care Med<\/em>. 32: 1740-1746. <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15286552?ordinalpos=13&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/p>\n<p><span>Quinton, LJ, Nelson, S, Zhang, P, <\/span><span>Bo\u00e9, DM, Happel, KI, and Bagby, GJ. 2004. Selective transport of cytokine-induced neutrophil chemoattractant from the lung to the blood facilitates pulmonary neutrophil recruitment. <em>Am. J. Physiol. Lung Cell Mol. Physiol<\/em>. 286(3): 465-472. <\/span><span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14617513?ordinalpos=14&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/span><\/p>\n<p>Mizgerd, JP. 2004. APC: Braking neutrophils to benefit patients? <em>Blood<\/em> 104:3841. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/apc-blood.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, MM Lupa, MR Spieker. 2004. NF-?B p50 facilitates neutrophil accumulation during LPS-induced pulmonary inflammation. <em>BMC Immunol.<\/em> 5:10. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/p50-bmcimmunology.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, MM Lupa, J Hjoberg, JC Vallone, HB Warren, JP Butler, ES Silverman. 2004. Roles for early response cytokines during <em>E. coli<\/em> pneumonia revealed by mice with combined deficiencies of all signaling receptors for TNF and IL-1. <em>Am. J. Physiol.<\/em> 286:L1302-L1310. <a href=\"http:\/\/ajplung.physiology.org\/cgi\/content\/full\/286\/6\/L1302\">Full text<\/a><\/p>\n<p>Wang, Q, CM Doerschuk, JP Mizgerd. 2004. Neutrophils in innate immunity. <em>Semin. Respir. Crit. Care Med.<\/em> 25:33-42. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=16088447&amp;query_hl=2\">PubMed<\/a><\/p>\n<p>Mizgerd, JP. 2003. Competing benefits of tumor necrosis factor- for bacteria and for host defense. <em>Am. J. Respir. Crit. Care Med.<\/em> 168:1410-1411. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/tnfeditorial-ajrccm.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, MM Lupa, MS Kogan, HB Warren, L Kobzik, GP Topulos. 2003. Nuclear factor-?B p50 limits inflammation and prevents lung injury during <em>Escherichia coli<\/em> pneumonia. <em>Am. J. Respir. Crit. Care Med.<\/em> 168:810-817. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/p50-ajrccm.pdf\">pdf<\/a><\/p>\n<p><span>Bo\u00e9, DM, Nelson, S, Zhang, P, Quinton LJ, Bagby, GJ. 2003. Alcohol-induced suppression of lung chemokine production and the host defense response to S<em>treptococcus pneumoniae<\/em>. <em>Alcohol: Clin. and Exp. Res<\/em>. 27: 1838-1845. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14634502?ordinalpos=22&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/span><\/p>\n<p><span>Happel KI, Zheng MQ, Young E, Quinton LJ, Lockhart E, Ramsay AJ, Shellito JE, Schurr JR, Bagby GJ, Nelson S, Kolls JK. 2003. Cutting Edge: Roles of toll-like receptor 4 and IL-23 in IL-17 expression in response to <em>Klebsiella pneumoniae<\/em> infection. <em>J. Immunol.<\/em>170: 4432-4436. <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12707317?ordinalpos=15&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/p>\n<p><span>Zhang, P, Quinton, LJ, Bagby, GJ, Summer, WR, Nelson, S. 2003. Interferon-gamma enhances the pulmonary CXC chemokine response to intratracheal lipopolysaccharide challenge. <em>J. Infect. Dis.<\/em> 187: 62-69. <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12508147?ordinalpos=16&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/p>\n<p>Mizgerd, JP, MR Spieker, MM Lupa. 2002. Exon truncation by alternative splicing of murine ICAM-1. <em>Physiol. Genomics<\/em> 12:47-51. <a href=\"http:\/\/physiolgenomics.physiology.org\/cgi\/content\/full\/12\/1\/47\">Full text<\/a><\/p>\n<p>Mizgerd, JP, ML Scott, MR Spieker, CM Doerschuk. 2002. I?B-beta independent regulation of acute inflammatory responses to <em>E. coli<\/em> lipopolysaccharide in mouse lungs. <em>Am. J. Respir. Cell Mol. Biol.<\/em> 27:575-582. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/IkB-AJRCMB.pdf\">pdf<\/a><\/p>\n<p>Tasaka, S, SE Richer, JP Mizgerd, CM Doerschuk. 2002. Very late antigen-4 in CD18-independent neutrophil emigration during acute bacterial pneumonia in mice. <em>Am. J. Respir. Crit. Care Med.<\/em> 166:53-60. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/vla4-ajrccm.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, J.P. 2002. Molecular mechanisms of neutrophil recruitment elicited by bacteria in the lungs. <em>Semin. Immunol.<\/em> 14:123-132. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/review-semimmunol.pdf\">pdf<\/a><\/p>\n<p><span>Quinton, LJ, Nelson, S, Bo\u00e9, DM, Zhang, P, Zhong, Q, Kolls, JK, Bagby, GJ. 2002. The granulocyte colony-stimulating factor response after intrapulmonary and systemic bacterial challenges.\u00a0<em>J. Infect. Dis.<\/em> 185: 1476-1482. <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11992284?ordinalpos=17&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Pubmed<\/a><\/p>\n<p>Alcamo, E, JP Mizgerd, BH Horwitz, R Bronson, AA Beg, M Scott, CM Doerschuk, RO Hynes, D Baltimore. 2001. Targeted mutation of tumor necrosis factor receptor 1 rescues the RelA-deficient mouse and reveals a critical role for NF-?B in leukocyte recruitment. <em>J. Immunol.<\/em> 167:1592-1600. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/rela-ji.pdf\">pdf<\/a><\/p>\n<p>Huang, C, GT De Sanctis, PJ O&#8217;Brien, JP Mizgerd, DS Friend, JM Drazen, LF Brass, RL Stevens. 2001. Human mast cell tryptase I: Evaluation of its substrate specificity and demonstration of its importance in bacterial infections of the lung. <em>J. Biol. Chem.<\/em> 276:26276-26284. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/tryptasebi-jbc.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, MR Spieker, CM Doerschuk. 2001. Early response cytokines and innate immunity: essential roles for TNFR1 and IL1R1 during <em>Escherichia coli<\/em> pneumonia in mice. <em>J. Immunol.<\/em> 166: 4042-4048. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/r1r1-ji.pdf\">pdf<\/a><\/p>\n<p>Horwitz, BH, JP Mizgerd, ML Scott, CM Doerschuk. 2001. Mechanisms of granulocytosis in the absence of CD18. <em>Blood<\/em> 97: 1578-1583. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/cd18circ-blood.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, JJ Peschon, CM Doerschuk. 2000. Roles of tumor necrosis factor receptor signaling during murine <em>E. coli<\/em> pneumonia. <em>Am. J. Respir. Cell Mol. Biol.<\/em> 22: 85-91. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/tnfr-ajrcmb.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, BH Horwitz, HC Quillen, ML Scott, CM Doerschuk. 1999. Effects of CD18-deficiency on the emigration of murine neutrophils during pneumonia. <em>J. Immunol.<\/em> 163: 995-999. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/cd18chimera-ji.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, DC Bullard, MJ Hicks, AL Beaudet, CM Doerschuk. 1999. Chronic Inflammatory Disease Alters Adhesion Molecule Requirements for Acute Neutrophil Emigration in Mouse Skin 1. <em>J. Immunol.<\/em> 162: 5444-5448. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/adhmolskin-ji.pdf\">pdf<\/a><\/p>\n<p>Palombo, JD, SJ DeMichele, PJ Boyce, EE Lydon, J Liu, Y Huang, RA Forse, JP Mizgerd, BR Bistrian. 1999. Short-term enteral feeding with diets containing eicosapentaenoic and ?-linolenic acids modulates alveolar macrophage fatty acid composition and eicosanoid synthesis without compromising bactericidal functions in rats. <em>Crit. Care Med.<\/em> 27:1908-1915. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=10507617&amp;query_hl=1\">PubMed<\/a><\/p>\n<p>Doerschuk, CM, JP Mizgerd, H Kubo, L Qin, T Kumasaka. 1999. Adhesion molecules and cellular biomechanical changes in acute lung injury. <em>Chest<\/em> 116: 37S-43S. <a href=\"http:\/\/www.chestjournal.org\/cgi\/content\/full\/116\/suppl_1\/37S-a\">Full text<\/a><\/p>\n<p>Mizgerd, JP, WM Quinlan, BW LeBlanc, GJ Kutkoski, DC Bullard, AL Beaudet, CM Doerschuk. 1998. Combinatorial requirements for adhesion molecules in mediating neutrophil emigration during bacterial peritonitis in mice. <em>J. Leukoc. Biol.<\/em> 64: 291-297. <a href=\"http:\/\/www.jleukbio.org\/cgi\/reprint\/64\/3\/291\">pdf<\/a><\/p>\n<p>Mizgerd, JP, H Kubo, GJ Kutkoski, SD Bhagwan, K Scharffetter-Kochanek, AL Beaudet, CM Doerschuk. 1997. Neutrophil emigration in the skin, lungs, and peritoneum: different requirements for CD11\/CD18 revealed by CD18-deficient mice. <em>J. Exp. Med.<\/em> 186: 1357-1364. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/cd18-jem.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, BB Meek, GJ Kutkoski, DC Bullard, AL Beaudet, CM Doerschuk. 1996. Selectins and neutrophil traffic: margination and <em>Streptococcus pneumoniae<\/em>-induced emigration in murine lungs. <em>J. Exp. Med.<\/em> 184: 639-645. <a href=\"https:\/\/www.bumc.bu.edu\/pneumonia\/files\/PDFs\/selectins-jem.pdf\">pdf<\/a><\/p>\n<p>Mizgerd, JP, RM Molina, RC Stearns, JD Brain, AE Warner. 1996. Gadolinium induces macrophage apoptosis. <em>J. Leukoc. 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Microbiol.<\/em> 31:124-128. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=7606187&amp;query_hl=1\">PubMed<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Shastry*, A, BE Hiller*, NL Sanders, AE Tseng, J Kothari, AK O\u2019Connell, HP Gertje, CT Ha, E Murzin, KE Traber, JA Lederer, MR Jones, F Douam, TG Beach, DG Remick, NA Crossland, S Monti, JD Campbell, JP Mizgerd. 2026. Sub-phenotypes of pneumonia defined by pulmonary histopathological features. bioRxiv\u00a0and Am J Respir Crit Care Med (in [&hellip;]<\/p>\n","protected":false},"author":1126,"featured_media":0,"parent":11,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/pneumonia\/wp-json\/wp\/v2\/pages\/13"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/pneumonia\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/pneumonia\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/pneumonia\/wp-json\/wp\/v2\/users\/1126"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/pneumonia\/wp-json\/wp\/v2\/comments?post=13"}],"version-history":[{"count":51,"href":"https:\/\/www.bumc.bu.edu\/pneumonia\/wp-json\/wp\/v2\/pages\/13\/revisions"}],"predecessor-version":[{"id":1155,"href":"https:\/\/www.bumc.bu.edu\/pneumonia\/wp-json\/wp\/v2\/pages\/13\/revisions\/1155"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/pneumonia\/wp-json\/wp\/v2\/pages\/11"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/pneumonia\/wp-json\/wp\/v2\/media?parent=13"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}