Program Seminar Series

Spring 2023

Programs in Physiology & Biophysics Seminar Series

Virtual Seminars are Tuesdays at 1pm, except as noted below

**If you want to attend a seminar and are not a member of P&B, please contact Michelle Wiggins for an invitation to the webinar.

Date	Speaker	Title & Host
1/31/23	Rajan Adhikari, PhD Boston University, P&B	Effect of Apo-opsin Content and Bicarbonate on Sensitivity in Vertebrate Photoreceptors (Host: Chris Gabel)
2/28/23	Ev Yemini, PhD UMass Medical School	In Living Color: Whole Nervous-System Cell Ids to Map Neural Communication and Fate in vivo (Host: Chris Gabel)
3/28/23	Neil Ganem, PhD Boston University, Pharmacology	Identifying Gene Dependencies in Highly-Aneuploid Human Cancers (Host: Chris Gabel)
4/11/23	Olga Gursky, PhD Boston University, P&B	Protein Amyloid Modulators: Structural Basis and Biological Ramifications (Host: Chris Gabel)
5/9/23	Chris Akey, PhD Boston University, P&B	The Yeast Nuclear Pore Complex: A Mechanosensitive Channel (Host: Chris Gabel)
5/22/23 Monday	Michael J. Robertson, PhD Stanford University School of Medicine, P&B	New Horizons in GPCR Structure Based Drug Discovery (Host: Venetia Zachariou)

Fall 2022

Department of Physiology & Biophysics Seminar Series

Virtual Seminars are Tuesdays at 1pm, except as noted below

**If you want to attend a seminar and are not a member of P&B, please contact Michelle Wiggins for an invitation to the webinar.

Date	Speaker	Title & Host
10/25/22	Laura Lowery, PhD Boston University	Regulation of Microtubule Dynamics During Growth Cone Guidance and Cell Migration (Host: Chris Gabel)
11/8/22	AP Sampath, PhD UCLA	Evolutionary Insights About Photon Detection and Retinal Processing From the Sea Lamprey Petromyzon Marinus (Host: Chris Gabel)
11/29/22	TBA	TBA
12/13/22	Dominique Frueh, PhD Johns Hopkins	Structural Dynamics as Protein Nervous Systems; Why and How to Study (Large) Peptide Synthetases by NMR (Host: Chris Gabel)
1/31/23	Rajan Adhikari, PhD P&B	Effect of Apo-opsin Content and Bicarbonate on Sensitivity in Vertebrate Photoreceptors (Host: Chris Gabel)

Spring 2022

Department of Physiology & Biophysics Seminar Series

Virtual Seminars are Tuesdays at 1pm, except as noted below

**If you want to attend a seminar and are not a member of P&B, please contact Michelle Wiggins for an invitation to the webinar.

Date	Speaker	Title & Host
2/8/22	Monika Oberer, PhD University of Graz, Austria	Peeking Behind the Veil of Lipid Mobilization From Fat Depots at the Molecular Level (Host: Assen Marintchev)
2/22/22	Post Doctoral Fellows P&B	TBA (P&B)
3/8/22	Michael Greenberg, MD/PhD Washington University	Precision Medicine for Heart Failure (Host: Bill Lehman)
3/22/22	Robert Austin, PhD BUSM	TBA (Host: Chris Gabel)
4/12/22	Rohit Kulkarni, MD/PhD	TBA (Host: Lynne Coluccio)
4/26/22	Graduate Students P&B	TBA (Host: P&B)

Fall 2021

Department of Physiology & Biophysics Seminar Series

Virtual Seminars are Tuesdays at 1pm, except as noted below

**If you want to attend a seminar and are not a member of P&B, please contact Michelle Wiggins for an invitation to the webinar.

Date	Speaker	Title & Host
9/9/21 *Thursday at 2:15pm	Djamel Lebeche, PhD Icahn School of Medicine	Cardiac Physiology under Diabetic Stress: Molecular Drivers and Signaling Defects (Host: Esther Bullitt)
9/14/21	Daniel Taub, PhD Harvard Med	New Biophysical Tools Uncover The Cortical Networks of Somatosensation (Host: Chris Gabel)
9/28/21	Erik Nelson, PhD University of Illinois	Using Cholesterol Biology To Re-Educate The Immune System In Cancer (Host: Mina Moussavi)
10/12/21	Jennie Luebke, PhD BUSM	Diversity and Selective Vulnerability of Cortical Neurons (Hosts: Chris Gabel/Carter Cornwall)
10/26/21	David Jacobson, PhD JILA	Probing the energetics of single membrane proteins by atomic force microscopy (Host: Esther Bullitt)
11/9/21	Annette Burgess, PhD University of Sydney School of Med	Team-based Learning: Key Steps, Theory and Practice (Host: Mina Moussavi)
11/30/21	Timothy Street, PhD Brandeis	Surprise Discoveries About the GRP94 Molecular Chaperone From Single-Molecule FRET Experiments (Host: Matt Doran)
12/14/21	Henry Ginsberg, MD Columbia	Assembly and Secretion of VLDL, Always Something New (Hosts: Xiaohu Mei/Haya Herscovitz)

Fall 2020/Spring 2021

Department of Physiology & Biophysics Seminar Series

Virtual Seminars are Thursdays at 2pm, except as noted below

**If you want to attend a seminar and are not a member of P&B, please contact Michelle Wiggins for an invitation to the webinar.

Date	Speaker	Title & Host
11/19/20	Xinchao Yu, PhD Amgen	NPC1L1—a cholesterol transporter (Host: Chris Akey)
12/3/20	Max Sokolov, PhD WVU Eye Institute	The journey of G protein in rod photoreceptors (Host: Clint Makino)
12/17/20	Roger Craig, PhD UMass Medical School	Cryo-EM structure of myosin II: how interactions between myosin’s heads and tail relax muscle and switch off cell motility (Hosts: Bill Lehman/Mike Rynkiewicz)
1/7/21	Huilin Li, PhD Van Andel Institute’s Center for Cancer and Cell Biology	Structural mechanisms of membrane lipid and membrane protein homeostasis. (Host: Chris Akey)
1/21/21	Andrei Korostelev, PhD University of Massachusetts Medical School	Ensemble and time-resolved cryo-EM elucidate translation accuracy and regulation (Host: Chris Akey)
2/4/21	Qiang Cui, PhD Department of Chemistry, Boston University	Multi-scale molecular simulation studies of biomolecular function (Host: Bill Lehman)
2/18/21	Edward Fisher, MD New York University Langone Medical Center	ApoB/VLDL and atherosclerosis (Host: Haya Herscovitz)
3/11/21	Steven Ludtke, PhD Baylor College of Medicine	In-situ structure and dynamics using Cryo-electron tomography (Host: Chris Akey)
3/25/21	Kenneth A. Taylor, PhD Florida State University	How the flight muscle of a giant water bug informs on muscle function and structure across species (Host: Chris Akey)
4/8/21	Irina Sereysheva, PhD The University of Texas Health Science Center at Houston	Gating mechanism of IP3R channels: insights from cryo-EM studies (Host: Chris Akey)
4/22/21	Niko Grigorieff, PhD University of Massachusetts Medical School	*Finding Needles in Haystacks – A New Approach to Template Matching (for in situ* Cryo-ET)** (Host: Chris Akey)
5/13/21	Thomas Guettler, PhD Max Planck Institute for Biophysical Chemistry	Targeting SARS-CoV-2 with camelid single-domain antibodies (Host: Chris Akey)
6/3/21	Michael Rout, PhD The Rockefeller University	NPC structure and facilitated transport (Host: Chris Akey)
6/24/21	Yunlu Xue, PhD Harvard Medical School	A new therapeutic gene to prolong cone survival in retinitis pigmentosa (Host: Chris Gabel)
8/10/21 **Tuesday @1pm	Patricia Aguilar-Calvo, DVM, PhD UCSD	Untangling the interactions of misfolded proteins with heparan sulfate in neurodegenerative disease (Host: Chris Gabel)

Summer 2020

Department of Physiology & Biophysics Seminar Series

Virtual Seminars 1:30pm, except as noted below

**If you want to attend a seminar and are not a member of P&B, please contact Prof. Esther Bullitt for an invitation to the webinar.

Date	Speaker	Title & Host
5/12/20	James Hamilton, PhD Physiology & Biophysics	Fatty Acid Transport Across Membranes (Host: Esther Bullitt)
5/21/20	Russek Day Boston University
5/28/20	Assen Marintchev, PhD Physiology & Biophysics	A quantitative view of translation initiation (Host: Esther Bullitt)
6/4/20	David Atkinson, PhD Physiology & Biophysics	40 years of Lipoprotein Research (Host: Esther Bullitt)
6/18/20 *1-3pm	Student Seminars Physiology & Biophysics	Angela Urdaneta – Optimizing ABCA1 Nanoparticle Reconstruction for Structural Studies Gregory Wirak – TBA Olivia Chavez – TBA Matthew Doran – TBA (Host: Esther Bullitt)
6/25/20 *10am	Polina Geva, PhD Physiology & Biophysics	TBA (Host: Esther Bullitt)
7/9/20	Malai Pavadai, PhD Physiology & Biophysics	TBA (Host: Esther Bullitt)
7/16/20	Dilip Yadav, PhD Physiology & Biophysics	TBA (Host: Esther Bullitt)

Upcoming Seminars

Department of Physiology & Biophysics

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
9/24/19	Zhera Sayers, PhD Sabanci University	Pushing the limits of Small and Wide Angle X-ray Scattering (SAXS/WAXS) with Ferric binding protein A (FbpA) from Heamophilus influenzae (Host: Jamie McKnight)
10/15/19	Olga Gursky, PhD Boston University	Serum Amyloid A: An enigmatic ancient protein with a new function in lipid transport and inflammation

Spring 2019

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
1/29/19	Soren Midtgaard, PhD Physiology & Biophysics	Selective deuteration and neutron scattering for structural biology (Host: David Atkinson)
2/5/19	Dan Oprian, PhD Brandeis	Retinylidene proteins in vision and as optogenetic tools
2/28/19	Neil Kad, PhD University of Kent	Walking the tightrope between DNA and actin binding proteins; single molecule insights into mechanism
3/12/19	Andras Malnasi Csizmadia, PhD Eötvös Loránd University	Motor Protein Pharmacology – Novel inhibitors for different myosin-2 isoforms: Implications for treatment of cardiovascular and skeletal muscle disease
3/26/19	Christna Ouch, PhD Physiology & Biophysics	TBA (Host: Chris Akey)
4/23/19	Phyllis Robinson, PhD Univ. of MD Baltimore County	TBA
5/7/19	Sebastian Guettler, PhD The Institute of Cancer Research, London England	TBA
5/14/19	John Tarbell, PhD City College of NY	TBA
5/21/19	Raul Pardon, PhD UMass Medical Center	TBA
6/4/19	Thomas Guettler, PhD UMass Medical Center	TBA (Host: Chris Akey)

Spring 2018

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
1/30/18	Stephen Farmer, PhD Biochemistry, BUMC	Mechano-responsive Signaling and Recruitment of Vascular Progenitors during Adipose Remodeling and Fibrosis (Host: Haya Herscovitz)
2/13/18	Nickolas Dickenson, PhD Utah State	*Powering Shigella* Infection: Structure-Function Studies of the Type Three Secretion System ATPase Spa47** (Host: Esther Bullitt)
2/22/18 *Thursday	Neil Kad, PhD University of Kent	TBA
2/27/18	Michael Do, PhD Boston Children’s Hospital	Encoding of Ambient Illumination within the Mammalian Retina
3/6/18	Catherine Royer, PhD RPI	Molecular Mechanisms of Cell Size Homeostasis in Budding Yeast (Host: Olga Gursky)
3/13/18	Farooq Kiani, PhD Boston University	Computational studies of molecular motors and proteins in the thin filament
4/4/17 *Wednesday @ 1pm	Stephen Blacklow, M.D./PhD Harvard	Unraveling Notch Signal Transduction (Host: Haya Herscovitz)
4/10/17	Jorge Haller, PhD Regeneron Pharmaceuticals	ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance (Host: Andy Zoeller)
5/8/17	Irina Serysheva, PhD The University of Texas	TBD (Host: Olga Gursky)

Fall 2017

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
9/19/17	Feng Li, PhD U Minnesota Twin Cities	“Coronavirus Spike Proteins: Structure, Function, and Vaccine Design” (Host: Andy Zoeller)
10/10/17	Gareth Morgan, PhD Department of Molecular and Experimental Medicine	“Stabilizing antibody light chains to prevent misfolding and aggregation” (Host: Andy Zoeller)
11/14/17	Yukio Fujiki, PhD Kyushu University	“Peroxisome Homeostasis: Biogenesis and Physiology” (Host: Andy Zoeller)
11/21/17	Ahmed El-Hussein, PhD Cairo University	TBA (Host: Clint Makino)
11/28/17	Les Loew, PhD UConn Medical	“The Virtual Cell Project” (Host: Bill Lehman)
12/5/17	Chunyu Wang, MD/PhD RPI	“Structural Mechanisms in Alzheimer’s disease and Protein Autoprocessing” (Host: Haya Hercovitz)
12/12/17	Bill Jackson, PhD University of Maryland School of Medicine	“Redirecting the Garbage Chute: Picornaviruses and Cellular Autophagy” (Host: Esther Bullitt)

Spring 2017

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
2/7/17	Igor Kaltashov, PhD University of Massachusetts Amherst	“New mass spectrometry-based tools to study protein structure and interactions” (Host: Olga Gusky)
2/16/17	Mike Geeves, PhD University of Kent	TBA (Host: Lynne Coluccio)
2/28/17	John Macor, PhD Genzyme/Sanofi	“What I Did on my Summer Vacation: Insights from a 30 Year Career in Drug Discovery.” (Host: Clint Makino)
3/14/17	Konstantin Zeldovic, PhD UMass Medical School	TBA (Host: Olga Gusky)
3/21/17	Rikard Frederiksen, PhD BUSM	“Visual adaptation: moving to the dark side” (Host: Clint Makino)
4/4/17	Jim Hurley, PhD University of Washington	“Energy metabolism in the retina ecosystem” (Host: Carter Cornwall)
4/25/17	King Wai Yau Johns Hopkins University School of Medicine	“Light Detection in the Eye — The Big Picture?” (Host: Clint Makino)
5/2/17	Eric Warrant, PhD Lund University	“Seeing at the limits: Vision and visual navigation in nocturnal insects” (Host: Rikard Frederiksen)
5/16/17	Joyce Wong, PhD Boston University	“Biomaterials to Detect and Treat Cardiovascular Disease” (Host: Bill Lehman)

Fall 2016

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
9/13/16	Shruthi Mahalingaiah, MD Boston Medical Center Dept of Obstetrics & Gynecology	Air Pollution Exposures & Gynecologic Disease Incidence: Physiology, Biological Mechanisms, and Epidemiology (Host: David Atkinson)
9/20/16	Koh Takeuchi, PhD National Institute of Advanced Industrial Science and Technology Tokyo, Japan	Utilization and extension of solution NMR techniques for biologically and clinically important systems (Host: Assen Marintchev)
Special Seminar 9/23/16 at 1pm in Rm L301	Maureen Basha, PhD West Virginia School of Osteopathic Medicine	Determinants of Cardiac Output (Host: Andy Zoeller)
9/27/16	Christopher Connor, MD/PhD Boston Medical Center Dept of Anesthesiology	High-intensity focused ultrasound and the advent of non-invasive brain surgery (Host: Chris Gable)
10/4/16	No Seminar	UMass Worcester CryoEM Opening Symposium
10/11/16	Deo Singh, PhD Johns Hopkins	Stabilization of EphA2 dimers as a novel anti-cancer strategy (Host: Clint Makino)
11/8/16	Mahdhurima Das BUSM, Dept of Physiology & Biophysics Dissertation Defense	Structural stability and lipid interactions in the misfolding of human apolipoprotein A-I: What makes the protein amyloidogenic? (Host: Olga Gursky)
11/29/16	Andrew Bogorad BUSM, Dept of Physiology & Biophysics Dissertation Defense	TBA (Host: Assen Marintchev)

Additional Boston area seminars

Spring 2016

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
1/19/16	Samuel Chung, PhD Department of Physiology and Biophysics BUSM	How can a simple roundworm and advanced optical techniques illuminate the path toward CNS regeneration? (Host: Carter Cornwall)
2/2/16	Brian Wainger, PhD Harvard Medical School	Stem Cell Modeling in Sensory and Motor Neuron Diseases
2/23/16	Mahmood Hussain, PhD	TBA
3/1/16	Vivek Venkatachalam, PhD Department of Physics, Harvard University	Pan-neuronal imaging in roaming C. elegans
3/29/16	Zhen Jiang, PhD BUSM, Department of Pharmacology and Experimental Therapeutics	Phosphoprotein CDP138 mediates stress-induced glucose and lipid metabolism
4/12/16	Lucy Forrest, PhD HIH/NINDA	TBA
4/19/16	Matt Gage, PhD UMass Lowell	Exploring the Role of the N2A Region of Titin in Skeletal Muscle Function

Additional Boston area seminars

Fall 2015

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
9/15/15	Mengwei Zang, M.D., PhD Department of Medicine, BUSM	Novel nutrient sensing in metabolic regulation and its therapeutic impact on diabetes (Host: Andy Zoeller)
9/29/15 *CVI Seminar, 12pm	Jay Horton, M.D. UT Southwestern	Molecular Mediators of Hepatic Steatosis
10/6/15 *CVI Seminar, 12pm	Ronglih Liao, PhD Brigham and Women’s	Autophagy, amyloid, and heart disease
*postponed	Laura Packer, PhD Takeda Pharmaceuticals	Antibody-Drug Conjugates and Process Development (Host: Jamie McKnight)
10/20/15	Teresa Ruiz, PhD University of Vermont	TBA
11/3/15	Tat Cheung Cheng, PhD BU Physiology and Biophysics, Post Doc CWA	Atomic model of the human and Drosophila apoptosome (Host: Chris Akey)
11/10/15 *CVI Seminar, 12pm	Monty Krieger, PhD MIT	Structure and functions of the HDL receptor: SRBI(Scavenger Receptor: Class B, Type I)
11/17/15 *CVI Seminar, 12pm	Michael Czech, PhD UMass School of Medicine	Cellular and Molecular Mechanisms underlying Systemic Glucose Intolerance
12/1/15	Isabel Morgado, PhD BU Physiology and Biophysics, Post Doc OG	Structural and biochemical basis of protein amyloid evolution: Transthyretin as a model of amyloid evolution (Host: Olga Gursky)
12/15/15	Hao Wu, PhD HMS	TBA

Additional Boston area seminars

Spring 2015

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
1/20/15	Michael Rynkiewicz, PhD BU Physiology & Biophysics Dept.	Engineering of Surfactant Proteins Reveals Mechanisms of Ligand Specificity (Host: Barbara Seaton)
1/27/15	Harrison Gabel, PhD HMS	The neuron-specific epigenome in neural development and disease (Host: Chris Gabel)
2/3/15	Dov Lichtenberg, PhD Tel Aviv Univ.	TBA (Host: Jim Hamilton)
2/5/15 *Thursday	Dietmar Manstein, PhD	The Structural Basis of Force Generation in Regulated Actomyosin Systems (Host: Lehman/Coluccio)
2/17/15	John Connor, PhD BUSM	I Inhaled What? Transcriptomic analysis of the host response following infection with viruses that cause hemorrhagic fever (Host: Barbara Seaton)
2/24/15	George Murphy, PhD BUSM	Pluripotent Stem Cell Modeling of Human Disease (Host: Jamie McKnight)
3/3/15	Rikard Frederiksen, PhD BUSM	The role of Meta III in regulating visual pigment regeneration in bleached mouse rods (Host: Carter Cornwall)
3/10/15	Jeffrey Holt, PhD HMS	Molecular composition of the elusive mechanosensory transduction channels that mediate hearing and balance (Host: Lynne Coluccio)
3/17/15	Eranthie Weerapana, PhD BC	Chemical-proteomic strategies to investigate reactive cysteines (Host: Barbara Seaton)
3/24/15	Maofu Liao, PhD HMS	Structural analysis of membrane proteins using single-particle cryo-electron microscopy” (Host: Chris Akey)
3/31/15	Ayyalusamy Ramamoorthy, PhD U Michigan	Structural Insights on Membrane-Bound Protein-Protein Complexes and Membrane-Mediated Misfolding of Amyloid Proteins (Host: Olga Gursky)
4/7/15	John Straub, PhD BU	Role of sequence and membrane in Amyloid Precursor Protein dimerization and cleavage (Host: Barbara Seaton)
4/14/15	Mo Khalil, PhD BU	Building molecular assemblies to control the flow of biological information (Host: Barbara Seaton)
4/21/15	Chelsea Epler, PhD BUSM	*Assembly of the Shigella flexneri* Type III Secretion Needle Tip** (Host: Esther Bullitt)
4/28/15	Tat Cheng, PhD BUSM	Apoptosome structure and procaspase activation (Host: Chris Akey)
5/5/15	Isabel Morgado, PhD BUSM	Molecular basis of β-Amyloid recognition with conformational antibody fragments (Host: Olga Gursky)
5/12/15	Departmental Graduate Student Seminar Day

Additional Boston area seminars

Fall 2014

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
9/11/14 *Time: 2:00pm 670 Albany St., Rm 107	Evan Daniel Rossignol BU Physiology & Biophysics Dept.	Thesis Defense: TOPOLOGY OF POLIOVIRUS RNA REPLICATION MACHINERY (Advisor: Esther Bullitt)
9/23/14	Lorenzo Finci, PhD Peking University and Dana-Farber Cancer Institute	Deciphering the signaling code for the wiring of the brain: The crystal structure of Netrin-1 in complex with Deleted in Colorectal Cancer (DCC) reveals the bi-functionality of Netrin-1 as a guidance cue (Host: Barbara Seaton)
9/30/14	Xiaohu Mei, PhD BUSM, Physiology and Biophysics Department	The Structure of apoA-I Reveals the Possible Mechanism of HDL Formation (Host: David Atkinson)
10/7/14	Adrian Whitty, PhD BU, Department of Chemistry	Quantitative characterization of the activation and signaling mechanism of a receptor tyrosine kinase (Host: Barbara Seaton)
10/14/14	Stuart Campbell, PhD Departments of Biomedical Engineering, and Cellular and Molecular Physiology, Yale University	Quantitative, Patient-Specific Approaches to Understanding Inherited Cardiomyopathies (Host: Bill Lehman)
10/21/14	Joseph Zaia, PhD BUSM, Department of Biochemistry	Glycosylation and the evolution of influenza virus fitness (Host: Barbara Seaton)
10/28/14	Daisy Sahoo, PhD Medical College of Wisconsin	HDL-cholesterol removal via SR-BI: The good, the bad, and the ugly (Host: David Atkinson)
11/4/14	Marek Orzechowski, PhD BUSM, Physiology and Biophysics Department	Tropomyosin movement on F-actin explained by energy landscapes (Host: Bill Lehman)
11/18/14	Anne Gershenson, PhD Department of Biochemistry & Molecular Biology, U Mass Amherst	Transient Interactions between Bacterial Phospholipase Cs and Membranes (Host: Barbara Seaton)
11/25/14	Hiroshi Tokuo, PhD BUSM, Physiology and Biophysics Department	Unconventional myosins in skin physiology (Host: Lynne Coluccio)
12/2/14	Barbara Brodsky, PhD Department of Biomedical Engineering, Tufts University	Collagen: Molecular Structure, pathological changes and recombinant applicationss (Host: Esther Bullitt)
12/9/14	Heidi Schwanz, PhD BUSM, Physiology and Biophysics Department	TBA (Host: Jim Hamilton)

Additional Boston area seminars

Spring 2014

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
1/14/14	John Samuelson, PhD Goldman School of Dental Medicine	The low-hanging fruit of cyst and oocyst walls: strategies to discover the structural components of the walls of parasitic protists (Host: Esther Bullitt)
1/21/14	Mason Klein, PhD Dept. of Physics, Harvard University	Cold avoidance, cold sensing, and cold circuits in the Drosophila larva (Host: Chris Gabel)
2/4/14	Tyler Reddy, PhD Dept. of Biochemistry, University of Oxford	Biophysical characterization of full-scale influenza and dengue virions (Host: Barbara Seaton)
2/11/14	Barbara Corkey, PhD Zoltan Kohn Professor of Medicine, BUSM	Redox Regulation in Obesity and Diabetes (Host: Haya Herscovitz)
2/25/14	Olivier Kocher, PhD Pathology, Harvard Medical School	Regulation of the HDL receptor SR-BI expression by the multi PDZ domain adaptor protein PDZK1 (Host: David Atkinson)
3/11/14	Zvonimir Dogic, PhD Dept of Physics, Brandeis University	From Molecular Motors and Microtubules to Synthetic Cilia and the Beyond (Host: Bill Lehman)
3/18/14 *Time: 9:30am	Daniel Saltzberg BU Physiology & Biophysics Dept.	Thesis Defense: Substrate Specificity and Conformational Activation Mechanism of Beta-Phosphoglucomutase (Advisor: Karen Allen)
3/25/14	Andrei Korostelev, PhD UMass Medical Center	TBA (Host: Chris Akey)
*Postponed*	George Murphy, PhD Hematology & Medical Oncology, BUSM	Pluripotent Stem Cell Modeling of Human Disease (Host: Andy Zoeller)
4/22/14	Wendy L. Picking, PhD Microbiology and Molecular Genetics, Oklahoma State University	No child should die from it: Toward a vaccine to prevent shigellosis (Host: Esther Bullitt)

Additional Boston area seminars

Fall 2013

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
9/3/13	Willy Wriggers, PhD D.E. Shaw Research	From Atoms to Living Organisms: Emergent Complexity of Multiscale Computational Modeling (Host: David Atkinson)
9/17/13	Hyesung Jeon, PhD Harvard Medical School	Molecular imaging and functional studies of EGFR pathway in cancer cells (Host: Graham Shipley)
10/1/13	Chris Akey, PhD Physiology & Biophysics – BUSM	Structure of the SecY channel at an early stage of protein translocation
10/22/13	Michael Regnier, PhD University of Washington	Mechanistic and translational studies of striated muscle contraction (Host: Bill Lehman)
10/29/13	Jeremiah Farelli, PhD Chemistry, Boston University	Panoramic functional view of the Haloalkanoic Acid Dehalogenase superfamily using a sparse sampling high-throughput approach.” (Host: Chris Akey)
11/5/13	Jeff Miller, PhD Neurology, BUSM	Molecular Pathogenesis of Muscular Dystrophies (Host: David Atkinson)
11/12/13	Steen Hansen, PhD Boston Children’s Hospital	Rho signaling in epithelial cell growth and cell death (Host: Lynne Coluccio)
12/3/13	David Harris, PhD Biochemistry, BUSM	The Prion Protein: A Dual Role in Prion and Alzheimer’s Diseases (Host: David Atkinson)
12/10/13	Michael Eck, PhD Dana Farber Cancer Institute	Structural approaches to understanding and targeting EGFR mutations in Lung Cancer (Host: Esther Bullitt)
1/14/13	John Samuelson, PhD Goldman School of Dental Medicine	The low-hanging fruit of cyst and oocyst walls: strategies to discover the structural components of the walls of parasitic protists (Host: Esther Bullitt)

Additional Boston area seminars

Spring 2013

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date	Speaker	Title & Host
1/10/13*Special Seminar: Thursday in Rm. R-115	Lynne M. Coluccio, PhD Boston Biomedical Research Institute	Mammalian class I myosins: Myo1c in adaptation in the inner ear and cell-cell contact (Host: Andy Zoeller)
1/22/13	Celia Schiffer, PhD University of Massachusetts Medical School	Combating Drug Resistance: Lessons from the Viral Proteases of HIV-1 and HCV (Host: Olga Gursky)
1/29/13	Stefan Raunser, PhD Max Planck Institute of Molecular Physiology	A Structural Biologist Looks at Molecular Life and Death of a Bug (Host: Bill Lehman)
2/19/13	Robert Griffin, PhD Massachusetts Institute of Technology	High Resolution Studies of Amyloid Fibrils (Host: Graham Shipley)
2/26/13	Mikel Garcia-Marcos, PhD Boston University School of Medicine	Discovering Novel G Protein Signaling Circuits: Implications in Cancer Metastasis (Host: David Atkinson)
3/12/13	Melissa Moore, PhD University of Massachusetts Medical School	Structure and Dynamics of Uber Complex RNPs (Host: Assen Marintchev)
3/19/13	Daniel Oprian, PhD Brandeis University	Structure and Mechanism of Proteins from the Rod Cell Phototransduction Cascade (Host: Carter Cornwall)
4/2/13	James Rothman, PhD Yale University School of Medicine	The Mechanism of Membrane Fusion and its Regulation for Quantal Synaptic Transmission (Host: Graham Shipley/David Harris)
4/9/13	Maureen Estevez, PhD Brown University	A Visual System in Vestibular Coordinates: The role of ON-type Direction-Selective Retinal Ganglion Cells in Retina and Brain (Host: Carter Cornwall)
4.23/13	Jorge Haller, PhD Massachusetts General Hospital	Role of the ABCA12 Lipid Transporter in Skin Ceramide Biosynthesis (Host: Andy Zoeller)
5/14/13	David Stokes, PhD Skirball Institute	A novel conformational change drives the alternating access mechanism for Zn²⁺ transport by YiiP (Host: Esther Bullitt)

Additional Boston area seminars

Fall 2012

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R103

Date	Speaker	Title & Host
9/25/12	Nikolaus Grigorieff, PhD Brandeis University	Restoring high-resolution contrast in images affected by beam-induced motion (Host: Chris Akey)
10/9/12	John Condeelis, PhD Albert Einstein College of Medicine	Mechanism-based insights into prognosis and treatment of breast cancer derived from high resolution multiphoton imaging (Host: Bill Lehman)
10/23/12	Michael Reedy, PhD Duke University	Time-Resolved Molecular Dynamics of Stretch Activation, Length-Dependent Activation and Force Generation in Insect Flight Muscle and Mammalian Heart (Host: Bill Lehman)
11/13/12	John Hartwig, PhD Harvard Medical School	The Filamins, organizers of cell structure, mechanics and function (Host: Bill Lehman)
11/20/12	Tim Gardner, PhD Boston University, Biology Dept.	Neural circuits and their development: vocal learning in songbirds (Host: Chris Gabel)
11/27/12	Wolfgang Peti, PhD Brown University	Structural mechanics and function of large protein signaling complexes (Host: Assen Marintchev)
12/4/12	Michael Previs, PhD University of Vermont	The molecular mechanics of cardiac myosin-binding Protein C in the modulation of cardiac contractility (Host: Jeff Moore/Bill Lehman)
12/11/12	Adam Cohen, PhD Harvard University	Optical electrophysiology with microbial rhodopsins (Host: Chris Gabel)
12/18/12 To be held in Kiefer Auditorium	Jack Szostak, PhD	TBA (Host: James Hamilton)

Additional Boston area seminars

Spring 2012

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R115

Date	Speaker	Title & Host
1/17/12	Didem Vardar, PhD Wellesly College	It is all in the details: Probing Notch regulation one amino acid at a time (Host: Jamie McKnight)
1/24/12	Allen Ehrlicher, PhD Harvard University	Molecular Mechanotransduction: How forces trigger cytoskeletal dynamics (Host: Jeff Moore)
1/31/12	David Weitz, PhD Harvard University	Fluctuations and Dynamics arrest in cells (Host: Bill Lehman)
2/21/12	Bert Van Den Berg, PhD U Mass Medical School	*Outer membrane uptake channels for small molecules in Pseudomonas aeruginosa* : Why so many?** (Host: Chris Akey)
3/6/12	Ty Chang, PhD Dartmouth Medical School	Cellular cholesterol esterification in atherosclerosis and neurodegenerative diseases (Host: Andy Zoeller)
3/13/12	Nurit Haspel, PhD U Mass Boston	Conformational exploration and self-assembly of protein molecules (Host: Barbara Seaton)
3/20/12	No Seminar
3/27/12	Sandor Vajda, PhD Boston University	TBA (Host: Barbara Seaton)
4/24/12	Douglas Golenbock, PhD UMass Medical School	TBA (Host: Andy Zoeller)
5/15/12	Athar Chishti, PhD Tufts University School of Medicine	Regulation of Cell Polarity (Host: Jamie McKnight)

Additional Boston area seminars

Fall 2011

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R103

Date	Speaker	Title & Host
9/13/11	Rahm Gummuluru, PhD BU School of Medicine	Parasitization of Dendritic Cell Functions by HIV (Host: Andy Zoeller)
9/27/11	Roberto Dominguez, PhD University of Penn School of Medicine	Structure-Function of Actin Filament Assembly (Host: Bill Lehman)
10/4/11	Natalia Beglova, PhD Harvard Medical School	On the way to understanding molecular mechanisms of antiphospholipid syndrome (Host: Olga Gursky)
10/11/11	Zemin Yao, PhD University of Ottawa	New insights into structure/function relationship within human apoB (Host: Jamie McKnight)
10/18/11	Dan Kirschner, PhD Boston College	Nerve Myelin: A New Rap On An Old Wrap – Pushing the Boundaries of Analysis (Host: Esther Bullitt)
10/25/11	David W. Christianson University of Pennsylvania	Evolutionary Divergence of Structure and Function in Arginase, Histone Deacetylase, and Polyamine Deacetylase (Host: Barbara Seaton)
11/1/11	Bob Murphy, PhD University of Colorado	TBA (Host: Andy Zoeller)
11/8/11	David Berson, PhD Brown University	TBA (Host: Carter Cornwall)
11/15/11	John Engen, PhD Northeastern University	Hydrogen exchange mass spectrometry to probe the conformation of proteins both in solution and in membranes (Host: Esther Bullitt)
12/6/11	Jim Baleja, PhD Tufts University School of Medicine	Structure and Function of EH domain Interactions in Endocytosis and Cell Signaling (Host: Barbara Seaton)
12/14/11 in rm. L301	Peter Gunning, PhD University of New South Wales	Tropomyosin diversifies actin cytoskeleton function in time and space and is a new target for chemotherapy (Host: Bill Lehman)

Additional Boston area seminars

Spring 2011

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R115

Date	Speaker	Title & Host
1/4/11	No Seminar
1/11/11	Suzanne Walker, PhD Harvard Medical School	Structure and Inhibition of Human O-GlcNAc transferase (Host: Jamie McKnight)
1/18/11	Charles Serhan, PhD Brigham and Women’s Hospital	Functional Metabolomics Uncover Novel Lipid Mediators in Resolving Inflammatory Exudates (Host: Donald M. Small)
1/25/11	Peter B. Moore, PhD Yale University	Conformational Contributions to Antibiotic Resistance: Lessons Learned from the Ribosome (Host: Graham Shipley)
2/1/11	Gerhard Wagner, PhD Harvard University	NMR studies of membrane proteins (Host: Assen Marintchev)
2/8/11	No Seminar
2/15/11	Frank McCormack, MD University of Cincinnati	Antimicrobial Functions of the Pulmonary Collectins (Host: Barbara Seaton)
2/22/11	Michael H. A. Roehrl, MD, PhD	Patholgy of Cancer (Host: Assen Marintchev)
3/1/11	David Berson, PhD Brown University	TBA (Host: Carter Cornwall)
3/8/11	No Seminar
3/15/11	John D. Gross, PhD UCSF	Insights into the structure, activity and control of HIV Vif (Host: Assen Marintchev)
3/22/11	Tatyana Svitkina, PhD University of Pennsylvania	Roles of Non-Muscle Myosin II in Protrusion, Adhesion and Contraction (Host: Bill Lehman)
3/29/11	Shujun Yuan, PhD Boston University	Structure and function of the apopt (Host: Christopher Akey)
4/5/11	Corey Wilson, PhD Yale University	Assembling a Molecular Switch: Reconciling Protein Folding And Design of a Complex System (Host: Jamie McKnight)
4/12/11	Daniel Rossignol, PhD Eisai Product Creation Systems	In vitro, in vivo and clinical development of a Toll-like receptor-4 antagonist (Host: Graduate Students)
4/19/11	Albert Wang, PhD BBRI	Actin Dynamics and Its Regulation by Caldesmon (Host: Bill Lehman)
4/26/11	Michael Welte, PhD University of Rochester	Fat, flies and videotape: Dynamic lipid droplets in Drosophila embryos (Host: Donald M. Small)
5/3/11	Xinchao Yu, PhD Research Fellow, Howard Hughes Medical Institute and the Structural Biology Program Sloan-Kettering Institute	Functional and Structural Studies of the Complex Between Coatomer and Arfl (Host: Chris Akey)
5/10/11	Michael Rynkiewicz, PhD Boston University School of Medicine Department of Physiology & Biophysics	Mechanisms of Interaction Between Surfactant Protein-D and Influenza A Virus Hemagglutinin (Host: Jim Head)
5/17/11	Jonathan Soboloff, PhD Temple University School of Medicine Assistant Professor, Dept. of Biochemistry Fels institute for Cancer Research and Molecular Biology	Mechanisms Regulating STIM Expression and Function in Ca² Signaling (Host: R. Andrew Zoeller)

Additional Boston area seminars

Fall 2010

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R103

Date	Speaker	Title & Host
9/28/10	Christopher Fang-Yen, PhD Harvard University, Department of Physics	Optical dissection of behavior in C. elegans (Host: Christopher Gabel)
10/05/10	No Seminar
10/12/10	Karen Allen, PhD CAS, Dept of Chemistry Boston University	Uncovering new functions in a super family of phosphatases (Host: Carter Cornwall)
10/19/10	No Seminar
10/26/10	Deborah Perlstein, PhD Boston University, CAS Chemistry	Microbe, Microbe, toxic microbe, How does your cell wall grow? (Host: Bill Lehman)
11/2/10	Thomas Charles Pochapsky, PhD Brandeis University Department of Chemistry	Are you my substrate? NMR insights into enzyme-substrate interactions (Host: Barbara Seaton)
11/9/10	Jim Hogle, PhD Harvard Medical School BU School of Medicine, Department of Biology	TBA (Host: Barbara Seaton)
11/16/10	Carlos Fernandez-Hernando, PhD NY University School of Medicine	miR-33 as a Therapeutic target for metabolic syndrome? (Host: Donald Small)
11/23/10	No Seminar
11/30/10	Rosalie K. Crouch, PhD Medical University of South Carolina Opthalmology	TBA (Host: Carter Cornwall)
12/7/10	Dagmar Ringe, PhD Brandeis University Departments of Biochemistry and Chemistry	TBA (Host: Barbara Seaton)
12/14/10	No Seminar
12/21/10	No Seminar

Additional Boston area seminars

Spring 2010

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm
Rm R115
Last update 7 January 2010

Date	Speaker	Title & Host
1/19/10	Samara Reck-Peterson, PhD Harvard University, Department of Cell Biology	Walking Mechanism of Cytoplasmic Dynein (Host: Dr. Bill Lehman)
1/26/10	Andres Leschziner, PhD Harvard University, Department of Molecular and Cellular Biology	Structural studies of ATP-dependent chromatin remodeling (Host: Dr. Christopher Akey)
2/09/10	John Straub, PhD Dept of Chemistry Boston University	Exploring the role of sequence and environment in the early stages of the protein aggregation pathway (Host: Dr. Barbara Seaton)
4/6/10	Vladimir Kefalov, PhD Dept Ophthalmology and Visual Sciences Washington University School of Medicine	Cone visual cycle in the vertebrate retina? (Host: Dr. Carter Cornwall)

Additional Boston area seminars

Fall 2009

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm,
Rm L301

Last update 24 August 2009

Date	Speaker	Title & Host
09/29/09	John Straub, PhD Dept of Chemistry, Theoretical & Computational Chemistry & Biophysics BU	TBA (Host: Dr. Barbara Seaton)
10/13/09	Donald M. Engelman, PhD Dept of Molecular Biology and Biophysics Yale University	TBA (Host: Dr. Graham Shipley)
10/20/09	Reid Gilmore, PhD Dept of Biochemistry and Molecular Pharmacology UMass Medical School	TBA (Host: Dr. Christopher Akey)
10/27/09	Michael C. Phillips, PhD Dept of Pediatrics UPenn	TBA (Host: Dr. Donald M. Small)
11/03/09	Douglas M. Swank, PhD Dept of Biology RPI	TBA (Host: Dr. Jeff Moore)
11/10/09	Uwe Beffert, PhD Dept of Biology BUSM	TBA (Host: Dr. Donald M. Small)
11/17/09	Osamu Shimomura, PhD BUSM Professor Emeritus	Special Seminar 3pm in the 670 Albany St. Auditorium
12/15/09	Bruce Furie, MD, PhDBIDMC Harvard University	TBA (Host: Dr. Barbara Seaton)

Additional Boston area seminars

Spring 2009

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm,
NEW ROOM: 670 Albany St, Rm 107/108

Last update 5 February 2009
Please contact Dr. Haya Herscovitz (haya@bu.edu) with any questions.

Date	Speaker	Title & Host
01/13/09	Monte Krieger, Ph.D. Dept. of Biology MIT	Charting the Fate of the ‘Good Cholesterol’ – Characterization of the HDL receptor SR-BI and its influence on Coronary Heart Disease
01/20/09	Dawn Braseamle, Ph.D. Dept. of Nutritional Sciences Rutgers University	Lipid Droplet-Associated Proteins Control Triacylglycerol Metabolism
02/03/09	Mary Roberts, Ph.D. Merkert Chemistry Center Boston College	Akt and PTEN: the yin and yang of signaling
02/10/09	Jane Kondev, Ph.D. Dept. of Physics Brandeis Univ.	Geography of bacterial chromosomes
02/17/09	Sunney Xiaoliang Xie, Ph.D. Dept. of Chemistry & Chem. Biol. Harvard Univ.	Holding Life Processes up to the Light, at the Single-Molecule Level
2/24/09	Lila Geirasch, Ph.D.Dept. of Biochem & Mol Biol, Dept of Chem U Mass, Amherst	(Host: Dr. James McKnight)
FRIDAY 02/27/09	Alexey Ladokhin, Ph.D. Dept. Biochem. & Mol. Biol. Kansas Univ. Medical Center	Thermodynamics of pH-Triggered Membrane Protein Insertion: what can we learn about membrane protein stability? (Host: Dr. Olga Gursky)
03/10/09	Adam Lerner, Ph.D. Dept. Medicine & Pathology Director, Hematology Training Pgm Boston Univ. School of Medicine	Mechanistic studies of the anti-estrogen resistance gene AND-34/BCAR3
03/17/09	Lee Makowski, Ph.D. Div. of Biological Sciences Argonne National Lab	Linking the Protein Ensemble to Function
03/31/09	John Clardy, Ph.D. Department of Biological Chemistry & Molecular Pharmacology Harvard Medical School	What We Can Learn from Bugs
04/07/09	Stanley Hazen, Ph.D. Dept. of Mol. Med. Cleveland Clinic, Lerner College of Medicine Case Western Reserve Univ.	Myloperoxidase, HDL and PON1 – functional partners in atherosclerosis (Host: Dr. Donald M. Small)
FRIDAY 04/17/09 9a-4:15p Rm R115	STUDENT SEMINAR DAY	Graduate Student Talks
FRIDAY 04/24/09 9a-4:15p Rm R115	STUDENT SEMINAR DAY	Graduate Student Talks
04/28/09	Dr. Mason W. Freeman Lipid Metabolism Unit Dept. of Medicine Mass General Hospital / Harvard Medical School	ABCA Transporters: Lipid Movers and Shakers (Host: Dr. David Atkinson)
05/05/09	Dr. Jim Delikatny Assistant Director, Molecular Imaging Laboratory Research Associate Professor, Dept. of Radiology University of Pennsylvania	Probing lipid metabolism non-invasively with MR and optical imaging (Host: Dr. David Atkinson)
06/16/09	Dr. Charles Sindelar Staff Scientist Dept. of Biochemistry Brandeis University	A ‘catalytic engine’ that accounts for kinesin motility and directionality (Host: Dr. William Lehman)

Fall 2008

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm, room L301

Last update 12/04/2008
You may contact Dr. Haya Herscovitz (haya@bu.edu), the fall seminar coordinator, with any questions.

Date	Speaker	Title & Host
9/2/08	Christopher Gabel, PhDHarvard University, Dept. Of Physics Dept. of Physiology & Biophysics	“The Study of Neural Regeneration in C. Elegans Using Femtosecond Laser Surgery” (Host: Dr. Andy Zoeller)
9/9/08	Alexei Kurakin, PhDBeth Israel Deaconess HospitalMedical Center	“Adaptice plasticity in protein interactions and cellular organization” (Host: Dr. Andy Zoeller)
9/19/08Friday	Hanna Rapaport, PhDBen-Gurion University of NegevDept. Biotechnology Engineering	“Structure of Amphiphilic Peptides at Interfaces” (Host: Dr. Donald M. Small)
9/23/08	Rajesh Ramachandran, PhDThe Scripps Research InstituteDept. Cell Biology – NEW Date!	Fluorescence-detected dynamics of dynamin-membrane interactions inclathrin-mediated endocytosis (Host: Dr. Andy Zoeller)
10/07/08	Kenneth Walsh, PhD,BU School of Medicine, Whitaker Cardiovascular Institute	TBA (Host: Dr. William Lehman)
10/21/08	Laura Liscum, PhDTufts School of Medicine, Dept. Physiology	TBA (Host: Haya Herscovitz and Barbara Schrieber)
10/28/08	Richard Cohen, PhDBU School of Medicine, Vascular Biology	Oxidative post-translational modification of proteins and cellular function (Host: Dr. Haya Herscovitz)
11/04/08	Matt Lang,Ph.D.MIT	Advances in Single Molecule Biophysics, Studies of Actin Machinery and the Force Generation Mechanism of Kinesin (Host: Dr. Haya Herscovitz and Michael Greenberg)
12/02/08	Alan Engelman, Ph.D.Dept. of Pathology Harvard Medical School	Integrase-Binding Co-factors and HIV-1 Infection
12/09/08	Charles Brenner, Ph.D.Depts. of Genetics & Biochemistry & the Norris Cotton Cancer CenterDartmouth Medical School	TBA
12/16/08	Lila Geirasch, Ph.D. Dept. of Biochem & Mol Biol, Dept of Chem U Mass, Amherst	POSTPONED due to weather (Host: Dr. James McKnight)

Spring 2008

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm, room L301

Date	Speaker	Title & Host
1/15/08	Dr. Karen AllenBoston University School of MedicineDept. of Physiology & Biophysics	“Structural Enzymology”
1/22/08	Dr. Biju PillaiBoston University School of Medicine Dept. of Physiology & Biophysics	“How fast do very long chain saturated fatty acids flip and flop?” (Host: Hamilton lab)
1/29/08	Dr. Krishna MurthyUniversity of Alabama at Birmingham	“Structure of ApoA-1” (Hosts: D. Atkinson, D. Small and G. Shipley)
2/12/08	Dr. Jonathan GoldbergMemorial Sloan-Kettering Cancer Center, New York	“Structure and Function of COPII Transport Vesicles” (Hosts: G. Shipley, C. Akey)
2/26/08	Dr. M. Elizabeth StroupeBrandeis University	“Structural studies of splicing complexes”(Host: E. Bullitt)
3/04/08	Dr. Barry Honig Center for Computational Biology and BioinformaticsColumbia University, New York	“Relating Cellular to Molecular Specificity”(Hosts: D. Small/D. Atkinson)
3/11/08	Dr. David RonSkirball Institute, New York University Medical Center	“Physiological considerations in unfolded protein responses” (Host: H. Herscovitz)
3/18/08	Dr. Rex F. Pratt, Ph.D.Professor of Biochemistryand Beach Professor of ChemistryWesleyan University	“Enzyme mechanisms” (Host: K. Allen)
3/25/08	Hwai-Chen Guo, Ph.D.BUSM	Glycosylasparaginase cis- to trans-hydrolysis of amide bonds
4/08/08	Dr. Martin KarplusHarvard University,Department of Chemistryand Chemical Biology	“How Proteins Work: Insights from Simulations” (Host: B. Lehman)
4/18/08 & 4/25/08	Student Seminar Days	(Hosts: Drs. C. Akey, K. Allen)
4/29/08	Dr. Ramanujan HegdeCell Biology and Metabolism Branch National Institute of Child Health and Human development (NIH)Bethesda, MD 20892	“The biosynthesis of secretory and membrane proteins” (Host: C. Akey)
5/06/08	Dr. Guangwei DuSUNY, Stonybrook (NY)Center for Developmental Genetics Dept. of Pharmacology	“Lipid signal regulation of membrane trafficking and oncogenesis” (Host: R.A. Zoeller)
Friday, 5/09/083:00pmRoom L303	Seemantini Nadkarni, PhDHarvard Medical School Massachusetts General HospitalWellman Center for Photomedicine	“Optical Techniques to Evaluate Atherosclerosis: a Multi-factorial Perspective” (Host: R.A. Zoeller)
5/13/08	Dr. Mary MunsonUMass Medical Center	“The Exocyst Complex: Molecular Architecture and Function in Exocytosis” (Host: CJ McKnight)
5/20/08	Norman A. Mazer, M.D., PhD Boston University School of Medicine	“A Physiologically-Based Mathematical Model of the Metabolic Clearance Rate of Testosterone” (Host: D. Atkinson)

Fall 2007

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm, room L301

Date	Speaker	Title & Host
9/18/07	Dr. Nicholas R. SilvaggiBoston University School of MedicineDept. of Physiology & Biophysics	“Structural Insights into Inhibition of the Clostridium botulinum Neurotoxin Serotype A Light Chain” (Host: Allen lab)
9/25/07	Dr. David Cane, Professor Brown University Department of Chemistry	“Nature’s Dirty Secrets” (Host: K. Allen)
10/09/07	Dr. Alexey OnufrievAssistant ProfessorDepartments of Computer Science and Physics, Virginia Tech	“Dynamics” (Host: B. Lehman)
10/16/07	Dr. Tom CroninUniversity of Maryland at Baltimore County in the Department of Biology	“Color Madness: The Evolution of Color and Polarization Vision in Mantis Shrimps”(Host: C. Cornwall)
10/23/07	Dr. Jay NeitzDepartment of Cell Biology, Neurobiology & Anatomy Medical College of Wisconsin	“Evolutionary endgame for the eye” or “Welcome to the wonderful world of color: gene therapy for colorblindness in a primate” (Host: C. Cornwall)
11/06/07	Dr. William BachovchinTufts University Biochemistry Department	“Are enzymes templates or mechanical devices?” (Host: J. Hamilton)
11/13/07	Dr. Michael RadermacherHealth Science Research Facility Univ of Vermont Medical School	“The Structure of Complex I in the Mitochondrial Respiratory Chain” (Host: C Akey)
11/27/07	Preethi ChandramouliBoston University School of MedicineDept. of Physiology & Biophysics	“Structure of the 80S ribosome” (Host: Akey lab)
12/04/07	Dr. Ernst J. Schaefer, MD Director, Cardiovascular Research & Lipid Metabolism Laboratories & Lipid and Heart Disease Prevention Program Tufts University School of Medicine Friedman School of Nutrition Science & Policy	“The Metabolism of High Density Lipoprotein Particles”(Host: J. Hamilton)
12/18/07	Dr. Jeff Hoch Department of Molecular, Microbial, and Structural BiologyUniversity of Connecticut Health Center	“Folding, Stability, and Structure of Human Prolactin” (Host: CJ. McKnight)

<!–[if gte mso 9]> Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 <![endif]–><!–[if gte mso 9]> <![endif]–> <!–[endif]–>Dr. Christopher Fang-Yen