{"id":800,"date":"2024-03-05T20:48:51","date_gmt":"2024-03-06T01:48:51","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/pbhi\/?page_id=800"},"modified":"2026-06-18T09:57:53","modified_gmt":"2026-06-18T13:57:53","slug":"recent-publications","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/pbhi\/news-updates\/recent-publications\/","title":{"rendered":"Publications &#038; Development"},"content":{"rendered":"<h2><span style=\"text-decoration: underline;\">2026:<\/span><\/h2>\n<p><a href=\"https:\/\/academic.oup.com\/sleep\/advance-article\/doi\/10.1093\/sleep\/zsag100\/8644007?guestAccessKey=\"><span style=\"font-weight: 400;\">Better sleep now, better cognition later? Predicting cognitive function using a machine learning-based sleep EEG brain health score<\/span> <b><i>(Sleep)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12779338\/\">Effectiveness of Self\u2010Administered Mobile Assessment in Detecting Mild Cognitive Impairment <em><strong>(Alzheimer&#8217;s &amp; Dementia Journal)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/link.springer.com\/article\/10.1186\/s12889-026-27524-9\"><span style=\"font-weight: 400;\">Gender differences in informal caregiving costs and burden in Alzheimer disease: a multinational cross-sectional analysis<\/span> <b><i>(Springer Nature)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/link.springer.com\/article\/10.1186\/s13195-026-02006-7\"><span style=\"font-weight: 400;\">Resource-stratified machine learning framework for cognitive status classification and mild cognitive impairment to dementia progression prediction <\/span><b><i>(Springer Nature)<\/i><\/b><\/a><\/p>\n<h2><span style=\"text-decoration: underline;\">2025:\u00a0<\/span><\/h2>\n<p><a href=\"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2841638\"><span style=\"font-weight: 400;\">Physical activity over the adult life course and risk of dementia in the Framingham Heart Study<\/span> <b><i>(JAMA Network Open)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12568389\/\"><span style=\"font-weight: 400;\">Higher vitamin B12 from mid- to late life is related to slower rates of cognitive decline <\/span><b><i>(Alzheimer&#8217;s &amp; Dementia)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40567106\/\"><span style=\"font-weight: 400;\">Association between education and rate of cognitive decline among individuals with Alzheimer&#8217;s disease: A multi-national European observational study <\/span><b><i>(Sage Journals)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/papers.ssrn.com\/sol3\/papers.cfm?abstract_id=5272191\"><span style=\"font-weight: 400;\">Integrating Clinical and Social Determinants of Health Data for Alzheimer&#8217;s Disease Risk Prediction: A Machine Learning Approach Using UK Biobank <\/span><b><i>(SSRN)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41598-025-95852-8\"><span style=\"font-weight: 400;\">Association of the digital clock drawing test with amyloid and tau PET biomarkers in low age risk adults <\/span><b><i>(Scientific reports)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/13872877251359889\"><span style=\"font-weight: 400;\">Developing an accessible dementia assessment tool: Leveraging a residual network, the trail making test, and demographic data <\/span><b><i>(Sage Journals)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/10.1002\/alz.70032\"><span style=\"font-weight: 400;\">Obfuscation via pitch-shifting for balancing privacy and diagnostic utility in voice-based cognitive assessment <\/span><b><i>(Alzheimer&#8217;s Association)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/academic.oup.com\/acn\/article\/40\/Supplement_2\/ii314\/8266481\"><span style=\"font-weight: 400;\">Test Complexity and Speed-Accuracy Dynamics Influence Practice Effects on Repeated Digital Self-Administered Cognitive Tasks <\/span><b><i>(Archives of Clinical Neuropsychology)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41598-025-95852-8\"><span style=\"font-weight: 400;\">Association of the digital clock drawing test with amyloid and tau PET biomarkers in low age risk adults <\/span><b><i>(Scientific reports)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/preprints.jmir.org\/preprint\/87208\"><span style=\"font-weight: 400;\">Task Complexity Amplifies Practice Effects on Quarterly Self-Administered Cognitive Tasks <\/span><b><i>(JMIR Publications)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12783218\/\">Digital Voice as an Alternative Screening Tool to the Montreal Cognitive Assessment <em><strong>(Alzheimer&#8217;s and Dementia Journal)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41177895\/\">Technological advances enabling an enhanced understanding of early Alzheimer&#8217;s disease <em><strong>(Alzheimer&#8217;s and Dementia Journal)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40911708\/\">Practice effects on digital cognitive assessment tools: insights from the defense automated neurobehavioral assessment battery <strong>(Alzheimer&#8217;s and Dementia Journal)<\/strong><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40038507\/\">Smartwatch- and smartphone-based remote assessment of brain health and detection of mild cognitive impairment <strong>(naturemedicine)<\/strong><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41050829\/\">Adherence timescale impacts completion rates of high-frequency mobile cognitive assessments among older adults <span style=\"text-decoration: underline;\"><em><strong>(Open Exploration)<\/strong><\/em><\/span><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40042504\/\">Dynamic lifetime risk prediction of Alzheimer&#8217;s disease with longitudinal cognitive assessment measurements <em><strong>(Alzheimer&#8217;s and Dementia Journal)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11408704\/\">A Network Analysis of Digital Clock Drawing for Command and Copy Conditions <em><strong>(Sage Journals)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40073397\/\">Digital Assessment of Cognitive Health in Outpatient Primary Care: Usability Study <em><strong>(JMIR Publications)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40636401\/\">PodGPT: an audio-augmented large language model for research and education <strong><em>(npj Biomedical Innovations)<\/em><\/strong><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40705832\/\">A natural language processing approach to support biomedical data harmonization: Leveraging large language models <em><strong>(PLOS One Journals)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40262110\/\">Precision neurocognition: An emerging diagnostic paradigm leveraging digital cognitive assessment technology <em><strong>(Sage Journals)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40285380\/\">Developing digital health technologies for frontotemporal degeneration <em><strong>(Alzheimer&#8217;s &amp; Dementia Journal)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40795277\/\">Health-oriented sleep states: making sleep states reflect health conditions <em><strong>(Sleep Research Society)<\/strong><\/em><\/a><em><strong>\u00a0<\/strong><\/em><\/p>\n<h2><span style=\"text-decoration: underline;\">2024:<\/span><\/h2>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41591-024-03118-z\"><span style=\"font-weight: 400;\">AI-based differential diagnosis of dementia etiologies on multimodal data <\/span><b><i>(nature medicine)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2024.11.06.24316862v1\"><span style=\"font-weight: 400;\">Association of DNA methylation age acceleration with digital clock drawing test performance: the Framingham Heart Study<\/span> <b><i>(medRxiv)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/www.jmir.org\/2024\/1\/e45780\"><span style=\"font-weight: 400;\">Cerebral Microbleeds in Different Brain Regions and Their Associations With the Digital Clock-Drawing Test: Secondary Analysis of the Framingham Heart Study <\/span><b><i>(JMIR Publications)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.123.032733\"><span style=\"font-weight: 400;\">Comparing Cognitive Tests and Smartphone-Based Assessment in 2 US Community-Based Cohorts <\/span><b><i>(AHAIASA Journals)\u00a0<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/aging.jmir.org\/2024\/1\/e55126\"><span style=\"font-weight: 400;\">Detection of Mild Cognitive Impairment From Non-Semantic, Acoustic Voice Features: The Framingham Heart Study <\/span><b><i>(JMIR Publications)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2274580724001328?via%3Dihub\"><span style=\"font-weight: 400;\">Erratum to: Digital Clock Drawing as an Alzheimer&#8217;s Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older Adults <\/span><b><i>(Science Direct)\u00a0<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/10.1002\/dad2.12574\"><span style=\"font-weight: 400;\">Exploring cognitive progression subtypes in the Framingham Heart Study<\/span> <b><i>(Alzheimer&#8217;s Association)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.27108\"><span style=\"font-weight: 400;\">The Relationship between Framingham Stroke Risk Profile on Incident Dementia and Alzheimer&#8217;s Disease: A 40-Year Follow-Up Study Highlighting Female Vulnerability <\/span><b><i>(Annals of Neurology)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/10.1002\/alz.13731\"><span style=\"font-weight: 400;\">Speech patterns during memory recall relates to early tau burden across adulthood <\/span><b><i>(Alzheimer&#8217;s Association)<\/i><\/b><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38924662\/\">Prediction of Alzheimer&#8217;s disease progression within 6 years using speech: A novel approach leveraging language models <strong>(Alzheimer&#8217;s &amp; Dementia Journal)<\/strong><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38348772\/\">Speech patterns during memory recall relates to early tau burden across adulthood <em><strong>(Alzheimer&#8217;s &amp; Dementia <\/strong><\/em><\/a><em><strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38348772\/\">Journal)\u00a0<\/a><\/strong><\/em><\/p>\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10966919\/\">Sex\u2010specific blood biomarkers linked to memory changes in middle\u2010aged adults: The Framingham Heart Study <em><strong>(Alzheimer&#8217;s &amp; Dementia Journal)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10902432\/\" target=\"_blank\" rel=\"noopener noreferrer\">Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates\u00a0<strong><em>(Frontiers in Neurology)<\/em><\/strong><\/a><\/p>\n<p><a href=\"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.123.031247\" target=\"_blank\" rel=\"noopener noreferrer\">Shifting from Active to Passive Monitoring of Alzheimer&#8217;s Disease: The State of the Research<em><strong> (Journal of the American Heart Association)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.123.032733\" target=\"_blank\" rel=\"noopener noreferrer\">Comparing Cognitive Tests and Smartphone\u2010Based Assessment in 2 US Community\u2010Based Cohorts <em><strong>(Journal of the American Heart Association)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.123.031348\" target=\"_blank\" rel=\"noopener noreferrer\">Design and Feasibility Analysis of a Smartphone\u2010Based Digital Cognitive Assessment Study in the Framingham Heart Study <em><strong>(Journal of the American Heart Association)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.123.030952\" target=\"_blank\" rel=\"noopener noreferrer\">Challenge of Optimizing Medical Therapy in Heart Failure: Unlocking the Potential of Digital Health and Patient Engagement <em><strong>(Journal of the American Heart Association)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.123.032870\" target=\"_blank\" rel=\"noopener noreferrer\">American Heart Association Focusing Research Rigor on Digital Health <em><strong>(Journal of the American Heart Association)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38230720\/\"><span>Digital Clock Drawing as an Alzheimer&#8217;s Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older Adults <em><strong>(The Journal of Prevention of Alzheimer&#8217;s Disease)<\/strong><\/em><\/span><\/a><\/p>\n<hr \/>\n<h2><span style=\"text-decoration: underline;\">2023:<\/span><\/h2>\n<p><a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/full\/10.1002\/dad2.12495\" target=\"_blank\" rel=\"noopener noreferrer\">Digital phenotyping: An equal opportunity approach to reducing disparities in Alzheimer&#8217;s disease and related dementia research <em><strong>(Alzheimer&#8217;s &amp; Dementia Journal)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/frdem.2023.1214940\/full\" target=\"_blank\" rel=\"noopener noreferrer\">Association between acoustic features and brain volumes: the Framingham Heart Study\u00a0<em><strong>(Frontiers in Dementia)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37808872\/\">Disease-driven domain generalization for neuroimaging-based assessment of Alzheimer&#8217;s disease\u00a0<em><strong>(medRxiv)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36519667\/\">BMI decline patterns and relation to dementia risk across four decades of follow-up in the Framingham Study<em>\u00a0<strong>(Alzheimer&#8217;s &amp; Dementia Journal)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/frdem.2023.1135451\/full\" target=\"_blank\" rel=\"noopener noreferrer\">Matching science to reality: how to deploy a participant-driven digital brain health platform <em><strong>(Frontiers in Dementia)<\/strong><\/em><\/a><\/p>\n<hr \/>\n<h2><span style=\"text-decoration: underline;\">2022:<\/span><\/h2>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41467-022-31037-5\" target=\"_blank\" rel=\"noopener noreferrer\">Multimodal deep learning for Alzheimer\u2019s disease dementia assessment\u00a0<em><strong>(Nature Communications)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/full\/10.1002\/alz.066006\" target=\"_blank\" rel=\"noopener noreferrer\">Feasibility of frequent self-administered mobile cognitive assessments in adults with and without cognitive impairment &#8211; Abstract <em><strong>(Alzheimer&#8217;s &amp; Dementia)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/full\/10.1002\/alz.066121\" target=\"_blank\" rel=\"noopener noreferrer\">Multimodal, longitudinal digital brain health platform using participant-driven study design &#8211; Abstract\u00a0<em><strong>(Alzheimer&#8217;s &amp; Dementia)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/full\/10.1002\/alz.064889\" target=\"_blank\" rel=\"noopener noreferrer\">Evaluation of COVID on cognitive performance using a mobile application &#8211; Abstract\u00a0<em><strong>(Alzheimer&#8217;s &amp; Dementia)<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/abs\/10.1002\/alz.065497\" target=\"_blank\" rel=\"noopener noreferrer\">Davos Alzheimer\u2019s Collaborative: Building a globally representative cohort through a technologically-enabled approach &#8211; Abstract\u00a0<em><strong>(Alzheimer&#8217;s &amp; Dementia)<\/strong><\/em><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>2026: Better sleep now, better cognition later? Predicting cognitive function using a machine learning-based sleep EEG brain health score (Sleep) Effectiveness of Self\u2010Administered Mobile Assessment in Detecting Mild Cognitive Impairment (Alzheimer&#8217;s &amp; Dementia Journal) Gender differences in informal caregiving costs and burden in Alzheimer disease: a multinational cross-sectional analysis (Springer Nature) Resource-stratified machine learning framework [&hellip;]<\/p>\n","protected":false},"author":22915,"featured_media":0,"parent":661,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"page-templates\/no-sidebars.php","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/pbhi\/wp-json\/wp\/v2\/pages\/800"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/pbhi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/pbhi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/pbhi\/wp-json\/wp\/v2\/users\/22915"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/pbhi\/wp-json\/wp\/v2\/comments?post=800"}],"version-history":[{"count":25,"href":"https:\/\/www.bumc.bu.edu\/pbhi\/wp-json\/wp\/v2\/pages\/800\/revisions"}],"predecessor-version":[{"id":1806,"href":"https:\/\/www.bumc.bu.edu\/pbhi\/wp-json\/wp\/v2\/pages\/800\/revisions\/1806"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/pbhi\/wp-json\/wp\/v2\/pages\/661"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/pbhi\/wp-json\/wp\/v2\/media?parent=800"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}