Publications & Development

2026:

Resource-stratified machine learning framework for cognitive status classification and mild cognitive impairment to dementia progression prediction (Springer Nature)

2025:

Physical activity over the adult life course and risk of dementia in the Framingham Heart Study (JAMA Network Open)

Higher vitamin B12 from mid- to late life is related to slower rates of cognitive decline (Alzheimer’s & Dementia)

Association between education and rate of cognitive decline among individuals with Alzheimer’s disease: A multi-national European observational study (Sage Journals)

Integrating Clinical and Social Determinants of Health Data for Alzheimer’s Disease Risk Prediction: A Machine Learning Approach Using UK Biobank (SSRN)

Association of the digital clock drawing test with amyloid and tau PET biomarkers in low age risk adults (Scientific reports)

Developing an accessible dementia assessment tool: Leveraging a residual network, the trail making test, and demographic data (Sage Journals)

Obfuscation via pitch-shifting for balancing privacy and diagnostic utility in voice-based cognitive assessment (Alzheimer’s Association)

Test Complexity and Speed-Accuracy Dynamics Influence Practice Effects on Repeated Digital Self-Administered Cognitive Tasks (Archives of Clinical Neuropsychology)

Association of the digital clock drawing test with amyloid and tau PET biomarkers in low age risk adults (Scientific reports)

Task Complexity Amplifies Practice Effects on Quarterly Self-Administered Cognitive Tasks (JMIR Publications)

Digital Voice as an Alternative Screening Tool to the Montreal Cognitive Assessment (Alzheimer’s and Dementia Journal)

Technological advances enabling an enhanced understanding of early Alzheimer’s disease (Alzheimer’s and Dementia Journal)

Practice effects on digital cognitive assessment tools: insights from the defense automated neurobehavioral assessment battery (Alzheimer’s and Dementia Journal)

Smartwatch- and smartphone-based remote assessment of brain health and detection of mild cognitive impairment (naturemedicine)

Adherence timescale impacts completion rates of high-frequency mobile cognitive assessments among older adults (Open Exploration)

Dynamic lifetime risk prediction of Alzheimer’s disease with longitudinal cognitive assessment measurements (Alzheimer’s and Dementia Journal)

A Network Analysis of Digital Clock Drawing for Command and Copy Conditions (Sage Journals)

Digital Assessment of Cognitive Health in Outpatient Primary Care: Usability Study (JMIR Publications)

PodGPT: an audio-augmented large language model for research and education (npj Biomedical Innovations)

A natural language processing approach to support biomedical data harmonization: Leveraging large language models (PLOS One Journals)

Precision neurocognition: An emerging diagnostic paradigm leveraging digital cognitive assessment technology (Sage Journals)

Developing digital health technologies for frontotemporal degeneration (Alzheimer’s & Dementia Journal)

Health-oriented sleep states: making sleep states reflect health conditions (Sleep Research Society)

2024:

AI-based differential diagnosis of dementia etiologies on multimodal data (nature medicine)

Association of DNA methylation age acceleration with digital clock drawing test performance: the Framingham Heart Study (medRxiv)

Cerebral Microbleeds in Different Brain Regions and Their Associations With the Digital Clock-Drawing Test: Secondary Analysis of the Framingham Heart Study (JMIR Publications)

Comparing Cognitive Tests and Smartphone-Based Assessment in 2 US Community-Based Cohorts (AHAIASA Journals)

Detection of Mild Cognitive Impairment From Non-Semantic, Acoustic Voice Features: The Framingham Heart Study (JMIR Publications)

Erratum to: Digital Clock Drawing as an Alzheimer’s Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older Adults (Science Direct)

Exploring cognitive progression subtypes in the Framingham Heart Study (Alzheimer’s Association)

The Relationship between Framingham Stroke Risk Profile on Incident Dementia and Alzheimer’s Disease: A 40-Year Follow-Up Study Highlighting Female Vulnerability (Annals of Neurology)

Speech patterns during memory recall relates to early tau burden across adulthood (Alzheimer’s Association)

Prediction of Alzheimer’s disease progression within 6 years using speech: A novel approach leveraging language models (Alzheimer’s & Dementia Journal)

Speech patterns during memory recall relates to early tau burden across adulthood (Alzheimer’s & Dementia Journal)

Sex‐specific blood biomarkers linked to memory changes in middle‐aged adults: The Framingham Heart Study (Alzheimer’s & Dementia Journal)

Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates (Frontiers in Neurology)

Shifting from Active to Passive Monitoring of Alzheimer’s Disease: The State of the Research (Journal of the American Heart Association)

Comparing Cognitive Tests and Smartphone‐Based Assessment in 2 US Community‐Based Cohorts (Journal of the American Heart Association)

Design and Feasibility Analysis of a Smartphone‐Based Digital Cognitive Assessment Study in the Framingham Heart Study (Journal of the American Heart Association)

Challenge of Optimizing Medical Therapy in Heart Failure: Unlocking the Potential of Digital Health and Patient Engagement (Journal of the American Heart Association)

American Heart Association Focusing Research Rigor on Digital Health (Journal of the American Heart Association)

Digital Clock Drawing as an Alzheimer’s Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older Adults (The Journal of Prevention of Alzheimer’s Disease)

2023:

Digital phenotyping: An equal opportunity approach to reducing disparities in Alzheimer’s disease and related dementia research (Alzheimer’s & Dementia Journal)

Association between acoustic features and brain volumes: the Framingham Heart Study (Frontiers in Dementia)

Disease-driven domain generalization for neuroimaging-based assessment of Alzheimer’s disease (medRxiv)

BMI decline patterns and relation to dementia risk across four decades of follow-up in the Framingham Study (Alzheimer’s & Dementia Journal)

Matching science to reality: how to deploy a participant-driven digital brain health platform (Frontiers in Dementia)

2022:

Multimodal deep learning for Alzheimer’s disease dementia assessment (Nature Communications)

Feasibility of frequent self-administered mobile cognitive assessments in adults with and without cognitive impairment – Abstract (Alzheimer’s & Dementia)

Multimodal, longitudinal digital brain health platform using participant-driven study design – Abstract (Alzheimer’s & Dementia)

Evaluation of COVID on cognitive performance using a mobile application – Abstract (Alzheimer’s & Dementia)

Davos Alzheimer’s Collaborative: Building a globally representative cohort through a technologically-enabled approach – Abstract (Alzheimer’s & Dementia)