{"id":8670,"date":"2024-09-13T09:22:49","date_gmt":"2024-09-13T13:22:49","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/neurology\/?post_type=profile&#038;p=8670"},"modified":"2024-09-13T09:24:54","modified_gmt":"2024-09-13T13:24:54","slug":"brian-j-coffey-md","status":"publish","type":"profile","link":"https:\/\/www.bumc.bu.edu\/neurology\/profile\/brian-j-coffey-md\/","title":{"rendered":"Brian J. Coffey, MD"},"content":{"rendered":"<p>Dr. Brian J. Coffey is a neurointensivist at Boston Medical Center and assistant professor of Neurology at Boston University Chobanian &amp; Avedisian School of Medicine. Dr. Coffey treats patients admitted to the Neurosciences Intensive Care Unit (NSICU), specializing in the treatment of severe brain injury, as well as other neurological conditions that require ICU care. He is passionate about providing exceptional\u00a0care to patients and supporting their families. Dr. Coffey\u2019s past research examined how the brain recovers language function after severe traumatic brain injury. His current research focuses on non-invasive monitoring of cerebral blood flow in the ICU after acute brain injury, such as after cardiac arrest, stroke, and traumatic brain injury. He aims to learn more about microcirculatory blood flow in the human brain post-injury, with the goal of determining if continuous cerebral blood flow monitoring could have clinical utility, possibly optimizing management approaches in the neuro ICU, improving patient outcomes, and aiding neuroprognostication. Dr. Coffey received his medical degree from Tufts University School of Medicine and his bachelor&#8217;s degree from Northeastern University. He completed his residency in neurology at UF Health Shands Hospital at the University of Florida, followed by his fellowship in neurocritical care at Boston Medical Center. Dr. Coffey is a member of the American Academy of Neurology, Neurocritical Care Society, American Medical Association, and the Massachusetts Medical Society.<\/p>\n<h5><span style=\"color: #008080;\">Publications<\/span><\/h5>\n<p><span class=\"read-more__more\" hidden=\"\"><span>Andriani G, Amata E, Beatty J, Clements Z, Coffey BJ, Courtemanche G, Devine W, Erath J, Juda CE, Wawrzak Z, Wood JT, Lepesheva GI, Rodriguez A, Pollastri MP. Antitrypanosomal lead discovery: identification of a ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth. J Med Chem. 2013 Mar 28;56(6):2556-67. doi: 10.1021\/jm400012e. Epub 2013 Mar 13. PMID: 23448316; PMCID: PMC3612894.<\/span><span>Andriani G, Amata E, Beatty J, Clements Z, Coffey BJ, Courtemanche G, Devine W, Erath J, Juda CE, Wawrzak Z, Wood JT, Lepesheva GI, Rodriguez A, Pollastri MP. Antitrypanosomal lead discovery: identification of a ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth. J Med Chem. 2013 Mar 28;56(6):2556-67. doi: 10.1021\/jm400012e. Epub 2013 Mar 13. PMID: 23448316; PMCID: PMC3612894.<\/span><\/span><\/p>\n<p>Andriani G, Amata E, Beatty J, Clements Z, <strong>Coffey BJ<\/strong>, Courtemanche G, Devine W, Erath J, Juda CE, Wawrzak Z, Wood JT, Lepesheva GI, Rodriguez A, Pollastri MP. Antitrypanosomal lead discovery: identification of a ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth. J Med Chem. 2013 Mar 28;56(6):2556-67. doi: 10.1021\/jm400012e. Epub 2013 Mar 13. PMID: 23448316; PMCID: PMC3612894.<\/p>\n<p><strong>Coffey BJ<\/strong>, Threlkeld ZD, Foulkes AS, Bodien YG, Edlow BL. Reemergence of the language network during recovery from severe traumatic brain injury: A pilot functional MRI study. Brain Inj. 2021 Nov 10;35(12-13):1552-1562. doi: 10.1080\/02699052.2021.1972455. Epub 2021 Sep 21. PMID: 34546806; PMCID: PMC8678186.<\/p>\n<p><span class=\"read-more__more\" hidden=\"\">care to patients and supporting their families. Dr. Coffey\u2019s past research examined how the brain recovers language function after severe traumatic brain injury. His current research focuses on non-invasive monitoring of cerebral blood flow in the ICU after acute brain injury, such as after cardiac arrest, stroke, and traumatic brain injury. He aims to learn more about microcirculatory blood flow in the human brain post-injury, with the goal of determining if continuous cerebral blood flow monitoring could have clinical utility, possibly optimizing management approaches in the neuro ICU, improving patient outcomes, and aiding neuroprognostication. Dr. Coffey received his medical degree from Tufts University School of Medicine and his bachelor&#8217;s degree from Northeastern University. He completed his residency in neurology at UF Health Shands Hospital at the University of Florida, followed by his fellowship in neurocritical care at Boston Medical Center. Dr. Coffey is a member of the American Academy of Neurology, Neurocritical Care Society, American Medical Association, and the Massachusetts Medical Society.<\/span><\/p>\n","protected":false},"author":935,"template":"","_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/profile\/8670"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/users\/935"}],"version-history":[{"count":2,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/profile\/8670\/revisions"}],"predecessor-version":[{"id":8672,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/profile\/8670\/revisions\/8672"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/media?parent=8670"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}