{"id":7107,"date":"2021-04-07T17:05:21","date_gmt":"2021-04-07T21:05:21","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/neurology\/?p=7107"},"modified":"2021-04-07T17:05:45","modified_gmt":"2021-04-07T21:05:45","slug":"research-and-scholarly-activity-education-seminar-9","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/neurology\/2021\/04\/07\/research-and-scholarly-activity-education-seminar-9\/","title":{"rendered":"Research and Scholarly Activity Education Seminar #9"},"content":{"rendered":"<h4><span style=\"color: #008080;\">How to Critically Evaluate a Clinical Study Publication<\/span><\/h4>\n<p><span style=\"color: #000000;\"><a href=\"https:\/\/www.bu.edu\/sph\/profile\/janice-weinberg\/\" style=\"color: #000000;\">Janice Weinberg, ScD<\/a>, Professor of Biostatistics at BUSPH, returns to discuss the statistical methods section in the paper, Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomized, non-inferiority trial. In this hour, she discusses the choice of a non-inferiority trial, its dependence upon the accepted standard of care, the need for definition of a non-inferiority margin, power and sample size, and special considerations for per-protocol and intention-to-treat analyses in a non-inferiority trial. Special thanks to <a href=\"https:\/\/www.bumc.bu.edu\/neurology\/profile\/david-y-chung-m-d-ph-d\/\" style=\"color: #000000;\">David Chung, MD, PhD<\/a>, Assistant Professor of Neurology in the Neurocritical Care Division for selecting the paper and providing the clinical context.<\/span><\/p>\n<p>Link to video <a href=\"https:\/\/mymedia.bu.edu\/media\/t\/1_ykj03rqk\">here<\/a>.<\/p>\n<p><img loading=\"lazy\" src=\"\/neurology\/files\/2021\/04\/Screen-Shot-2021-04-06-at-10.31.46-PM.png\" alt=\"\" width=\"838\" height=\"479\" class=\"alignnone wp-image-7108\" srcset=\"https:\/\/www.bumc.bu.edu\/neurology\/files\/2021\/04\/Screen-Shot-2021-04-06-at-10.31.46-PM.png 2478w, https:\/\/www.bumc.bu.edu\/neurology\/files\/2021\/04\/Screen-Shot-2021-04-06-at-10.31.46-PM-525x300.png 525w, https:\/\/www.bumc.bu.edu\/neurology\/files\/2021\/04\/Screen-Shot-2021-04-06-at-10.31.46-PM-1024x585.png 1024w, https:\/\/www.bumc.bu.edu\/neurology\/files\/2021\/04\/Screen-Shot-2021-04-06-at-10.31.46-PM-768x439.png 768w, https:\/\/www.bumc.bu.edu\/neurology\/files\/2021\/04\/Screen-Shot-2021-04-06-at-10.31.46-PM-1536x878.png 1536w, https:\/\/www.bumc.bu.edu\/neurology\/files\/2021\/04\/Screen-Shot-2021-04-06-at-10.31.46-PM-2048x1170.png 2048w\" sizes=\"(max-width: 838px) 100vw, 838px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>How to Critically Evaluate a Clinical Study Publication Janice Weinberg, ScD, Professor of Biostatistics at BUSPH, returns to discuss the statistical methods section in the paper, Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomized, non-inferiority trial. In this hour, she discusses the choice of a non-inferiority trial, its dependence upon the accepted [&hellip;]<\/p>\n","protected":false},"author":935,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2783],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/posts\/7107"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/users\/935"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/comments?post=7107"}],"version-history":[{"count":2,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/posts\/7107\/revisions"}],"predecessor-version":[{"id":7110,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/posts\/7107\/revisions\/7110"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/media?parent=7107"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/categories?post=7107"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/tags?post=7107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}