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Neuromuscular diseases are common, many of which are debilitating. Research is critically important to the understanding of disease pathogenesis and the development of effective therapies. The Neuromuscular Division at the Boston Medical Center is dedicated to providing excellent clinical care to patients with neuromuscular diseases and conducting clinical and basic research. The division chief Dr. Peter Siao studies electrophysiological features of neuromuscular diseases to improve disease diagnosis. Drs. Ariel Marks and Deandrea King collaborate with investigators in the nationally renowned Boston University Amyloidosis Center to study genotype-phenotype correlation and to test novel therapies for hereditary transthyretin-mediated amyloid polyneuropathy. Dr. Lan Zhou and Dr. Xingyu Wang have conducting NIH R01-supported basic research to study muscle inflammation, muscular dystrophy, and muscle injury repair. Dr. Zhou and Dr. Sachiko Homma also have NIH funding to study mechanisms underlying muscle pain and fatigue in long COVID.<\/span><\/p>\n Peter Siao, MD<\/a>, Division Chief Abrams RMC, Zhou L, Shin SC. Persistent post-COVID-19 neuromuscular symptoms. Muscle Nerve. 2023 Jul 19. PMID:\u00a037466117<\/a>; DOI:\u00a010.1002\/mus.27940<\/a><\/span><\/p>\n Wang X, Chen J, Homma ST, Wang Y, Smith GR, Ruf-Zamojski F, Sealfon SC, Zhou L. Diverse effector and regulatory functions of fibro\/adipogenic progenitors during skeletal muscle fibrosis in muscular dystrophy. iScience. 2023 Jan 20; 26(1):105775.\u00a0PMID:\u00a036594034<\/a>; PMCID:\u00a0PMC9804115<\/a>; DOI:\u00a010.1016\/j.isci.2022.105775<\/a><\/span><\/p>\n Wang X, Zhou L. The Many Roles of Macrophages in Skeletal Muscle Injury and Repair. Front Cell Dev Biol. 2022; 10:952249. PMID:\u00a035898401<\/a>; PMCID:\u00a0PMC9309511<\/a>; DOI:\u00a010.3389\/fcell.2022.952249<\/a><\/span><\/p>\n Abrams RMC, Simpson DM, Navis A, Jette N, Zhou L, Shin SC. Comment on small fiber neuropathy associated with SARS-CoV-2 infection: Author response. Muscle Nerve. 2022 Jun; 65(6):E32-E33. PMID:\u00a035385186<\/a>; PMCID:\u00a0PMC9088413<\/a>; DOI:\u00a010.1002\/mus.27555<\/a><\/span><\/p>\n Rodr\u00edguez-Moreno J, Zhou L, Arkun K, Bali D, Reed D, Kalish R, Vullaganti M, Bali T, Soto \u00d3. Tarui Disease Caused by a Novel PFKM Genetic Variant in a Sub-Saharan African Patient. J Clin Neuromuscul Dis. 2022 Mar 01; 23(3):162-164. PMID:\u00a035188917<\/a>; DOI:\u00a010.1097\/CND.0000000000000349<\/a><\/span><\/p>\n Bhadola S, Tang C, Marks A, Kaku MC, Zhou L, Siao P, Lau KHV. Disparate healthcare access and telehealth-based hybrid consultations during the COVID-19 pandemic. Work. 2022; 73(2):377-382.View Related Profiles.\u00a0PMID:\u00a035938279<\/a>; DOI:\u00a010.3233\/WOR-211463<\/a><\/span><\/p>\n Abrams RMC, Simpson DM, Navis A, Jette N, Zhou L, Shin SC. Small fiber neuropathy associated with SARS-CoV-2 infection. Muscle Nerve. 2022 04; 65(4):440-443. PMID:\u00a034766365<\/a>; PMCID:\u00a0PMC8661991<\/a>; DOI:\u00a010.1002\/mus.27458<\/a><\/span><\/p>\n Lau KHV, Kaku MC, Marks A, Tang C, Zhou L, Siao P. Optimizing the operation of an electrodiagnostic laboratory during the COVID-19 pandemic: A 6-month single-center experience. Muscle Nerve. 2021 09; 64(3):361-364.View Related Profiles.\u00a0PMID:\u00a034131929<\/a>; PMCID:\u00a0PMC8441863<\/a>; DOI:\u00a010.1002\/mus.27352<\/a><\/span><\/p>\n Anand P, Zhou L, Bhadelia N, Hamer DH, Greer DM, Cervantes-Arslanian AM. (2021) Neurologic Findings Among Inpatients With COVID-19 at a Safety-net US Hospital.\u00a0Neurol Clin Pract.<\/em>\u00a011(2):e83-e91. PMID: 33842075<\/span><\/p>\n Zhou L. Small Fiber Neuropathy in the Elderly. (2021)\u00a0Clin Geriatr Med.<\/em>\u00a037(2):279-288. PMID: 33858610<\/span><\/p>\n Zhou L, Siao P. (2021) Lateral femoral cutaneous neuropathy caused by prone positioning to treat COVID-19-associated acute respiratory distress syndrome.\u00a0Muscle Nerve.<\/em>\u00a02021 Feb 12. PMID: 33577110<\/span><\/p>\n Rubenstein AB, Smith GR, Raue U, Begue G, Minchev K, Ruf-Zamojski F, Nair VD, Wang X, Zhou L, Zaslavsky E, Trappe TA, Trappe S, Sealfon SC (2020). Single-cell transcriptional profiles in human skeletal muscle.\u00a0Sci Rep.<\/em>\u00a010(1):229. doi: 10.1038\/s41598-019-57110-6. PMID: 31937892<\/span><\/p>\n Anand P, Slama MCC, Kaku M, Ong C, Cervantes-Arslanian AM, Zhou L, David WS, Guidon AC. (2020) COVID-19 in patients with myasthenia gravis.\u00a0Muscle Nerve.<\/em>\u00a062(2):254-258. PMID: 32392389<\/span><\/p>\n Wang X, Sathe AA, Smith GR, Ruf-Zamojski F, Nair V, Lavine KJ, Xing C, Sealfon SC, Zhou L. (2020) Heterogeneous origins and functions of mouse skeletal muscle-resident macrophages.\u00a0Proc Natl Acad Sci U S A.<\/em>\u00a0117(34):20729-20740. PMID: 32796104<\/span><\/p>\n Anand P, Slama MCC, Kaku M, Ong C, Cervantes-Arslanian AM, Zhou L, David WS, Guidon AC. (2020) Comment on COVID-19 in patients with myasthenia gravis: Author response.\u00a0Muscle Nerve.<\/em>\u00a012; 62(6):E87-E88. PMID: 32954519<\/span><\/p>\n Zhou L (2019) Small Fiber Neuropathy.\u00a0Semin Neurol.<\/em>\u00a039(5):570-577. PMID: 31639840<\/span><\/p>\n Siao P, Kaku M. A Clinician\u2019s Approach to Peripheral Neuropathy (2019).\u00a0Semin Neurol.<\/em>\u00a039(5):519-530.<\/span><\/p>\n Kaku M,\u00a0Siao\u00a0P. Peripheral Neuropathies.\u00a0Semin\u00a0Neurol<\/em>. 2019 Oct; 39(5):517-518. PMID: 31639834.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":" Neuromuscular diseases are common, many of which are debilitating. Research is critically important to the understanding of disease pathogenesis and the development of effective therapies. The Neuromuscular Division at the Boston Medical Center is dedicated to providing excellent clinical care to patients with neuromuscular diseases and conducting clinical and basic research. The division chief Dr. […]<\/p>\n","protected":false},"author":935,"featured_media":0,"parent":7222,"menu_order":8,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/pages\/7256"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/users\/935"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/comments?post=7256"}],"version-history":[{"count":13,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/pages\/7256\/revisions"}],"predecessor-version":[{"id":8759,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/pages\/7256\/revisions\/8759"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/pages\/7222"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/neurology\/wp-json\/wp\/v2\/media?parent=7256"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Faculty:<\/strong><\/span><\/h5>\n
\nDeandrea King, MD<\/a>
\nAriel Marks, MD<\/a>
\nRachel A. Caplan, MD<\/a>
\nSachiko Homma, PhD
\nXingyu Wang, PhD<\/a><\/p>\nCurrent Studies and Grants:<\/strong><\/span><\/h5>\n
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Recent Publications:<\/strong><\/span><\/h5>\n