{"id":2689,"date":"2016-11-06T17:53:22","date_gmt":"2016-11-06T22:53:22","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/msr\/?page_id=2689"},"modified":"2017-06-05T17:22:21","modified_gmt":"2017-06-05T21:22:21","slug":"strap","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/msr\/software\/strap\/","title":{"rendered":"STRAP"},"content":{"rendered":"

STRAP: Software for Researching Annotations of Proteins<\/strong><\/p>\n

STRAP<\/strong> (Software Tool for Rapid Annotation of Proteins) is a software program developed at the Cardiovascular Proteomics Center of Boston University School of Medicine (Boston, MA). The program automatically annotates a protein list with information that helps in the meaningful interpretation of data from mass spectrometry and other techniques.<\/p>\n

<\/p>\n

STRAP Overview<\/strong><\/p>\n

Hardware Requirements<\/strong>
\nSTRAP requires Windows XP or higher with at least version 3.5 of the Microsoft .NET Framework installed.<\/p>\n

Input Requirements<\/strong>
\nSTRAP takes protein lists as input in the form of text files, protXML files (usually generated by the Trans-Proteomic Pipeline<\/a>), or DAT files (from Mascot<\/a> search results).<\/p>\n

Example of Result Pages<\/strong>
\nSTRAP downloads information from the Uniprot<\/a> and EBI QuickGO<\/a> databases to generate protein annotation tables and a variety of GO charts to aid in the individual and differential analysis of proteomics data. Examples of these results are shown in the three figures below.<\/p>\n

 <\/p>\n

\n
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\"A<\/a>Protein annotation table for one sample<\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

\n
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\"GO<\/a>GO annotation pie chart for one sample<\/em><\/div>\n
<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

<\/p>\n

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\"GO<\/a>GO annotation bar chart comparing three samples<\/em><\/div>\n
<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

Download Software<\/strong><\/p>\n

Please select Download<\/a> for the STRAP program (version 1.5) and the STRAP tutorial sample files.<\/p>\n

Tutorial<\/strong>
\nPlease select Tutorial<\/a> for the STRAP tutorial.<\/p>\n

Quick Start<\/strong>
\nPlease select Quick Start<\/a>\u00a0to get started using STRAP.<\/p>\n

Contact Us<\/strong>
\nPlease select Contact Us<\/a> for assistance with any STRAP problems.<\/p>\n

Disclaimer<\/strong>
\nSTRAP software was developed at the Cardiovascular Proteomics Center of Boston University School of Medicine (Boston, MA). The program is freely available for external testing. We assume no responsibility for its use, and we make no guarantees, whether expressed or implied, about its performance or any other characteristics. We would appreciate acknowledgment of our organization if the software is used.<\/p>\n

Publications<\/strong>
\n\u2022Software tool for researching annotations of proteins: Open-source protein annotation software with data visualization
\nVivek N. Bhatia, David H. Perlman, Catherine E. Costello, and Mark E. McComb, Analytical Chemistry 2009, 81(23), 9819-23.
\nConference Presentations<\/strong>
\n\u2022Peptide and PTM biomarkers of cardiovascular disease in a mouse model
\nMark E. McComb, David H. Perlman, Stephen A. Whelan, Deborah A. Siwik, Vivek N. Bhatia, Wilson Colucci, Richard A. Cohen, and Catherine E. Costello, ASMS 2011, Denver, CO.
\n\u2022Software tool for researching annotations of proteins (STRAP): Open-source software for protein annotation and data visualization
\nVivek N. Bhatia, David H. Perlman, Catherine E. Costello, and Mark E. McComb, ASMS 2009, Philadelphia, PA.<\/p>\n","protected":false},"excerpt":{"rendered":"

STRAP: Software for Researching Annotations of Proteins STRAP (Software Tool for Rapid Annotation of Proteins) is a software program developed at the Cardiovascular Proteomics Center of Boston University School of Medicine (Boston, MA). The program automatically annotates a protein list with information that helps in the meaningful interpretation of data from mass spectrometry and other […]<\/p>\n","protected":false},"author":1068,"featured_media":0,"parent":1457,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages\/2689"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/users\/1068"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/comments?post=2689"}],"version-history":[{"count":11,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages\/2689\/revisions"}],"predecessor-version":[{"id":2842,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages\/2689\/revisions\/2842"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages\/1457"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/media?parent=2689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}