{"id":23,"date":"2001-11-16T00:00:00","date_gmt":"2001-11-16T04:00:00","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/msr\/research-topics\/cd1c\/"},"modified":"2012-07-29T00:33:27","modified_gmt":"2012-07-29T04:33:27","slug":"cd1c","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/msr\/research-topics\/cd1c\/","title":{"rendered":"CD1c"},"content":{"rendered":"<p><img src=\"https:\/\/www.bumc.bu.edu\/msr\/files\/Images\/small_naturesmallsize.jpg\" alt=\"\" class=\"alignright\" \/><br \/>\n<strong>CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection<\/strong><\/p>\n<p>\nA collaboration in immunology&#8230;<\/p>\n<p>\nA recent article collaborating with Prof. Branch Moody<\/p>\n<p>\nMass Spectrometry was used to identify and structurally define a previously unknown lipid antigen isolated from tuberculosis bacteria. Both low energy CID MS\/MS and high energy CID with accurate mass measurement were used for determination of the pseudo-isoprenoid structure of the lipid chain. The structure of the saccharide moiety was determined by permethylation followed by GCMS for determination of the substitution pattern.<\/p>\n<p>\nFor more information, please visit <a href=\"http:\/\/www.nature.com\" target=\"blank\">www.nature.com<\/a>, or contact <a href=\"mailto:cecmsms@bu.edu\">Cathy Costello<\/a> for reprints.<\/p>\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection A collaboration in immunology&#8230; A recent article collaborating with Prof. Branch Moody Mass Spectrometry was used to identify and structurally define a previously unknown lipid antigen isolated from tuberculosis bacteria. Both low energy CID MS\/MS and high energy CID with accurate mass measurement were used [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":6,"menu_order":21,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages\/23"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/comments?post=23"}],"version-history":[{"count":1,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages\/23\/revisions"}],"predecessor-version":[{"id":1640,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages\/23\/revisions\/1640"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/pages\/6"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/msr\/wp-json\/wp\/v2\/media?parent=23"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}