Sayon Roy PhD, FARVO

Professor, Endocrinology, Diabetes, Nutrition & Weight Management

Professor, Ophthalmology

650 Albany St | (617) 638-4110
Sayon Roy

Endocrinology, Diabetes, Nutrition & Weight Management


Evans Center for Interdisciplinary Biomedical Research


My expertise is in understanding the pathogenesis of diabetic microvascular complications. In particular, studying the effect of high glucose in retinal endothelial cells, pericytes, and Muller cell gene expression.

Other Positions


PhD, Boston University, 1990

MS, University of Kalyani, 1983

BS, University of Kalyani, 1976


Published on 6/3/2021

Kim D, Sesaki H, Roy S. Reduced Levels of Drp1 Protect against Development of Retinal Vascular Lesions in Diabetic Retinopathy. Cells. 2021 06 03; 10(6). PMID: 34204906.

Published on 5/31/2021

Kim D, Votruba M, Roy S. Opa1 Deficiency Promotes Development of Retinal Vascular Lesions in Diabetic Retinopathy. Int J Mol Sci. 2021 May 31; 22(11). PMID: 34072974.

Published on 11/21/2020

Herdade AS, Silva IM, Calado Â, Saldanha C, Nguyen NH, Hou I, Castanho M, Roy S. Effects of Diabetes on Microcirculation and Leukostasis in Retinal and Non-Ocular Tissues: Implications for Diabetic Retinopathy. Biomolecules. 2020 11 21; 10(11). PMID: 33233433.

Published on 11/19/2020

Kim D, Lewis CS, Sarthy VP, Roy S. High-Glucose-Induced Rab20 Upregulation Disrupts Gap Junction Intercellular Communication and Promotes Apoptosis in Retinal Endothelial and Müller Cells: Implications for Diabetic Retinopathy. J Clin Med. 2020 Nov 19; 9(11). PMID: 33227912.

Published on 9/18/2020

Roy S, Kim D. Retinal capillary basement membrane thickening: Role in the pathogenesis of diabetic retinopathy. Prog Retin Eye Res. 2021 05; 82:100903. PMID: 32950677.

Published on 8/3/2020

Kim D, Roy S. Effects of Diabetes on Mitochondrial Morphology and Its Implications in Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2020 08 03; 61(10):10. PMID: 32756920.

Published on 7/10/2020

Kim D, Sankaramoorthy A, Roy S. Downregulation of Drp1 and Fis1 Inhibits Mitochondrial Fission and Prevents High Glucose-Induced Apoptosis in Retinal Endothelial Cells. Cells. 2020 07 10; 9(7). PMID: 32664237.

Published on 4/9/2020

Nguyen NH, Kim D, Roy S. High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2020 04 09; 61(4):40. PMID: 32340032.

Published on 9/21/2019

Subramanian ML, Stein TD, Siegel N, Ness S, Fiorello MG, Kim D, Roy S. Upregulation of Lysyl Oxidase Expression in Vitreous of Diabetic Subjects: Implications for Diabetic Retinopathy. Cells. 2019 09 21; 8(10). PMID: 31546618.

Published on 9/16/2019

Kim D, Lee D, Trackman PC, Roy S. Effects of High Glucose-Induced Lysyl Oxidase Propeptide on Retinal Endothelial Cell Survival: Implications for Diabetic Retinopathy. Am J Pathol. 2019 10; 189(10):1945-1952. PMID: 31537300.

View full list of 63 publications.