Mengze Li
Postdoctoral Associate, Computational Biomedicine
72 E. Concord St Evans Building | (929) 310-0418vmli@bu.edu
Publications
Sebastiani P, Reed E, Chandler KB, Lopez P, Lords H, Bae H, Costello CE, Au M, Deng LL, Li M, Xiang Q, Noh H, Pflieger L, Funk C, Rappaport N, Nygaard M, Short MI, Brent M, Monti S, Andersen SL, Perls TT. A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E. Adv Sci (Weinh). 2026 Jan; 13(4):e09764. PMID: 41316897.
Published on 1/3/2025Gurinovich A, Song Z, Bae H, Leshchyk A, Li M, Lords H, Andersen SL, Nygaard M, Christensen K, Daw EW, Arbeev KG, Brent MR, Perls TT, Sebastiani P. SNP rs6543176 is associated with extreme human longevity but increased risk for cancer. Geroscience. 2025 Jun; 47(3):3163-3168. PMID: 39751714.
Published on 11/5/2024Sebastiani P, Monti S, Lustgarten MS, Song Z, Ellis D, Tian Q, Schwaiger-Haber M, Stancliffe E, Leshchyk A, Short MI, Ardisson Korat AV, Gurinovich A, Karagiannis T, Li M, Lords HJ, Xiang Q, Marron MM, Bae H, Feitosa MF, Wojczynski MK, O'Connell JR, Montasser ME, Schupf N, Arbeev K, Yashin A, Schork N, Christensen K, Andersen SL, Ferrucci L, Rappaport N, Perls TT, Patti GJ. Metabolite signatures of chronological age, aging, survival, and longevity. Cell Rep. 2024 Nov 26; 43(11):114913. PMID: 39504246.
Published on 7/25/2024Reed ER, Chandler KB, Lopez P, Costello CE, Andersen SL, Perls TT, Li M, Bae H, Soerensen M, Monti S, Sebastiani P. Cross-platform proteomics signatures of extreme old age. Geroscience. 2025 Feb; 47(1):1199-1220. PMID: 39048883.
Published on 6/4/2024Li M, Song Z, Gurinovich A, Schork N, Sebastiani P, Monti S. yQTL Pipeline: A structured computational workflow for large scale quantitative trait loci discovery and downstream visualization. PLoS One. 2024; 19(6):e0298501. PMID: 38833463.
Published on 12/21/2022Bae H, Gurinovich A, Karagiannis TT, Song Z, Leshchyk A, Li M, Andersen SL, Arbeev K, Yashin A, Zmuda J, An P, Feitosa M, Giuliani C, Franceschi C, Garagnani P, Mengel-From J, Atzmon G, Barzilai N, Puca A, Schork NJ, Perls TT, Sebastiani P. A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants. Int J Mol Sci. 2022 Dec 21; 24(1). PMID: 36613555.
Published on 9/23/2022Gurinovich A, Li M, Leshchyk A, Bae H, Song Z, Arbeev KG, Nygaard M, Feitosa MF, Perls TT, Sebastiani P. Evaluation of GENESIS, SAIGE, REGENIE and fastGWA-GLMM for genome-wide association studies of binary traits in correlated data. Front Genet. 2022; 13:897210. PMID: 36212134.
Published on 8/23/2022Sebastiani P, Song Z, Ellis D, Tian Q, Schwaiger-Haber M, Stancliffe E, Lustgarten MS, Funk CC, Baloni P, Yao CH, Joshi S, Marron MM, Gurinovich A, Li M, Leshchyk A, Xiang Q, Andersen SL, Feitosa MF, Ukraintseva S, Soerensen M, Fiehn O, Ordovas JM, Haigis M, Monti S, Barzilai N, Milman S, Ferrucci L, Rappaport N, Patti GJ, Perls TT. A metabolomic signature of the APOE2 allele. Geroscience. 2023 Feb; 45(1):415-426. PMID: 35997888.
Published on 3/1/2022Vanuytsel K, Villacorta-Martin C, Lindstrom-Vautrin J, Wang Z, Garcia-Beltran WF, Vrbanac V, Parsons D, Lam EC, Matte TM, Dowrey TW, Kumar SS, Li M, Wang F, Yeung AK, Mostoslavsky G, Dries R, Campbell JD, Belkina AC, Balazs AB, Murphy GJ. Multi-modal profiling of human fetal liver hematopoietic stem cells reveals the molecular signature of engraftment. Nat Commun. 2022 03 01; 13(1):1103. PMID: 35232959.