Hong Y. Luo MD, PhD

Research Assistant Professor, Hematology & Medical Oncology

88 E. Newton St | (617) 638-4569
Hong Luo
Sections

Hematology & Medical Oncology

Centers

Center of Excellence in Sickle Cell Disease

Biography

Expertise includes: Molecular hematology; Hemoglobin gene regulation.

Education

MD, Zhongshan Medical University, 1976

PhD, McMaster University, 1993

MSc, China Academy of Chinese Medical Sciences (CACMS), 1981

Publications

Published on 11/29/2017

Morrison TA, Wilcox I, Luo HY, Farrell JJ, Kurita R, Nakamura Y, Murphy GJ, Cui S, Steinberg MH, Chui DHK. A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression. Blood Cells Mol Dis. 2018 03; 69:1-9. PMID: 29227829.

Published on 2/27/2017

Jiang Z, Luo HY, Farrell JJ, Zhang Z, Schulz VP, Albarawi D, Steinberg MH, Al-Allawi NAS, Gallagher PG, Forget BG, Chui DHK. A variant Sp1 (R218Q) transcription factor might enhance HbF expression in ß0 -thalassaemia homozygotes. Br J Haematol. 2018 03; 180(5):755-757. PMID: 28240767.

Published on 1/19/2017

Park S, Gianotti-Sommer A, Molina-Estevez FJ, Vanuytsel K, Skvir N, Leung A, Rozelle SS, Shaikho EM, Weir I, Jiang Z, Luo HY, Chui DHK, Figueiredo MS, Alsultan A, Al-Ali A, Sebastiani P, Steinberg MH, Mostoslavsky G, Murphy GJ. A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 Apr 11; 8(4):1076-1085. PMID: 28111279.

Published on 8/22/2016

Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, Mostoslavsky G, Murphy GJ, Patra PK, Chui DH, Alsultan A, Al-Ali AK, Sebastiani P, Steinberg MH. A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. Am J Hematol. 2016 Nov; 91(11):1118-1122. PMID: 27501013.

Published on 4/28/2016

Luo HY, Chui DH. Diverse hematological phenotypes of ß-thalassemia carriers. Ann N Y Acad Sci. 2016 Mar; 1368(1):49-55. PMID: 27123947.

Published on 4/13/2016

Shaikho EM, Habara AH, Alsultan A, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Patra PK, Sebastiani P, Baltrusaitis K, Farrell JJ, Jiang Z, Luo HY, Chui DH, Al-Ali AK, Steinberg MH. Variants of ZBTB7A (LRF) and its ß-globin gene cluster binding motifs in sickle cell anemia. Blood Cells Mol Dis. 2016 07; 59:49-51. PMID: 27282567.

Published on 1/13/2016

Jiang Z, Luo HY, Huang S, Farrell JJ, Davis L, Théberge R, Benson KA, Riolueang S, Viprakasit V, Al-Allawi NA, Ünal S, Gümrük F, Akar N, Basak AN, Osorio L, Badens C, Pissard S, Joly P, Campbell AD, Gallagher PG, Steinberg MH, Forget BG, Chui DH. The genetic basis of asymptomatic codon 8 frame-shift (HBB:c25_26delAA) ß(0) -thalassaemia homozygotes. Br J Haematol. 2016 Mar; 172(6):958-65. PMID: 26771086.

Published on 10/27/2015

Dai Y, Sangerman J, Luo HY, Fucharoen S, Chui DH, Faller DV, Perrine SP. Therapeutic fetal-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms. Blood Cells Mol Dis. 2016 Jan; 56(1):62-9. PMID: 26603726.

Published on 9/15/2015

Akinbami AO, Campbell AD, Han ZJ, Luo HY, Chui DH, Steinberg MH. Hereditary Persistence of Fetal Hemoglobin Caused by Single Nucleotide Promoter Mutations in Sickle Cell Trait and Hb SC Disease. Hemoglobin. 2016; 40(1):64-5. PMID: 26372199.

Published on 10/27/2014

Edward HL, Pisani LA, Rodriguez-Romero WE, Chaves-Villalobos J, Garcia-Quesada J, Harris NS, Luo HY, Steinberg MH, Forget BG, Chui DH. Hb Youngstown [ß101(G3)Glu???Ala; HBB: c.305A > C]: An unstable hemoglobin variant causing severe hemolytic anemia. Hemoglobin. 2014; 38(6):381-4. PMID: 25347256.

View full list of 30 publications.