{"id":869,"date":"2010-07-12T08:42:53","date_gmt":"2010-07-12T12:42:53","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/immunology\/?page_id=869"},"modified":"2018-12-06T12:43:33","modified_gmt":"2018-12-06T17:43:33","slug":"cytokinechemokine-biology","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/immunology\/research\/cytokinechemokine-biology\/","title":{"rendered":"Cytokine\/Chemokine Biology"},"content":{"rendered":"<p>Immunology Training Program is interested in identifying links between molecular mechanisms of cytokine production and inflammatory disease, with emphasis on type 2 diabetes as a more recently recognized inflammatory disorder. Cells of both the innate and adaptive immune system categories hyper-produce pro-inflammatory cytokines in diabetes patients. In some cases, the immune cells also hypo-produce anti-inflammatory cytokines, which likely exacerbates the physiological impact of elevated pro-inflammatory cytokine levels. Identifying cellular and molecular mechanisms that explain cytokine imbalance in type 2 diabetes increases the scope of immunological research into the traditional realm of metabolic research. The long-term goal of this approach is to identify immunological targets to expand the limited arsenal of type 2 diabetes treatments currently used in the clinic.<\/p>\n<p>Faculty involved in this research are:<\/p>\n<ul>\n<li><a title=\"David M. Center, MD\" href=\"https:\/\/www.bumc.bu.edu\/immunology\/faculty\/center\/\">David Center<\/a><\/li>\n<li><a title=\"Joseph P. Mizgerd, ScD\" href=\"https:\/\/www.bumc.bu.edu\/immunology\/faculty\/mizgerd-2\/\">Joseph Mizgerd<\/a><\/li>\n<li><a title=\"Daniel G. Remick, MD\" href=\"https:\/\/www.bumc.bu.edu\/immunology\/faculty\/remick\/\">Daniel Remick<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Immunology Training Program is interested in identifying links between molecular mechanisms of cytokine production and inflammatory disease, with emphasis on type 2 diabetes as a more recently recognized inflammatory disorder. Cells of both the innate and adaptive immune system categories hyper-produce pro-inflammatory cytokines in diabetes patients. In some cases, the immune cells also hypo-produce anti-inflammatory [&hellip;]<\/p>\n","protected":false},"author":1171,"featured_media":0,"parent":809,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/immunology\/wp-json\/wp\/v2\/pages\/869"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/immunology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/immunology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/immunology\/wp-json\/wp\/v2\/users\/1171"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/immunology\/wp-json\/wp\/v2\/comments?post=869"}],"version-history":[{"count":11,"href":"https:\/\/www.bumc.bu.edu\/immunology\/wp-json\/wp\/v2\/pages\/869\/revisions"}],"predecessor-version":[{"id":3022,"href":"https:\/\/www.bumc.bu.edu\/immunology\/wp-json\/wp\/v2\/pages\/869\/revisions\/3022"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/immunology\/wp-json\/wp\/v2\/pages\/809"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/immunology\/wp-json\/wp\/v2\/media?parent=869"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}