{"id":30220,"date":"2013-06-26T16:18:04","date_gmt":"2013-06-26T20:18:04","guid":{"rendered":"http:\/\/www.bumc.bu.edu\/gms\/?page_id=30220"},"modified":"2026-02-23T11:29:22","modified_gmt":"2026-02-23T16:29:22","slug":"newly-approved-gms-courses","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/gms\/academics\/registration\/newly-approved-gms-courses\/","title":{"rendered":"Newly Approved GMS Courses"},"content":{"rendered":"

GMS AN 728: Topics in Neurophysiology<\/h4>
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This course will provide you with an overview of the structural and functional properties of neurons and their synapses. We will review the methods used to study neuronal properties and the underlying molecular mechanisms that determine neuronal function. Through didactic lectures given by departmental experts, you will learn how to interpret scientific data regarding principles of the action potential, synaptic transmission, molecular signaling, synaptic plasticity, and sensory perception. Through in-class problem sets, you will apply your knowledge of the neurophysiological principles that underly neuronal signaling and explore how neurophysiological processes apply to the function of the nervous system. (2cr)<\/span><\/p>\n

COURSE INSTRUCTOR: <\/strong>Jeannine Foley<\/p>\n

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GMS BD 740: Cancer Bioinformatics<\/h4>
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The Cancer Bioinformatics course provides an in-depth exploration of advanced computational methods and analysis in cancer research. Students will analyze high-throughput sequencing data, including mutation calling, copy number alterations, discovery of mutations that drive tumor development and tumor phylogenies, while learning statistical modeling and machine learning techniques. The course integrates computational tools such as Linux, Python, and R alongside cloud platforms like Terra and Docker, to process and visualize large-scale datasets. Topics include next-generation sequencing (NGS), tumor biology, RNA-Seq, single-cell RNA-Seq, DNA repair signatures, proteomics, and epigenetics. Emphasizing both theoretical foundations and practical skills, the course prepares students to tackle complex challenges in cancer genomics and clinical bioinformatics. (3cr)<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

COURSE INSTRUCTORS:\u00a0<\/strong>Ignaty Leshchiner<\/p>\n

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GMS OH 733: Physiology B\/Dental<\/h4>
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Prereq: Must be in the Oral Health Sciences program. (4cr)<\/span><\/p>\n

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This course is a continuation of GMS OH 732.<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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COURSE INSTRUCTOR:\u00a0<\/strong>William Lehman<\/div>\n
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GMS PM 803: Systems Pharmacology & Therapeutics<\/h4>
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The requested change consolidates this two-semester course into a single semester while retaining the same underlying course concepts described above. This revised version course offers that same in-depth analysis of major drug classes used in the treatment of neurological, cardiovascular, immune-related, infectious diseases and a number of other severe chronic disorders that have presented a therapeutic challenge. Special attention is given to the molecular, cellular, and circuit-specific actions of novel pharmacological agents. The course begins with foundational reviews of disease mechanisms, followed by emerging concepts and innovative treatment strategies. Discussions focus on comparing new approaches to current standards of care, critically analyzing their therapeutic advantages. This course will be required for PhD students in the Biomolecular Pharmacology Training Program as well and will typically be taken in the second semester of the first year of study. It is also open as an elective to PhD students in other biomedical science programs. (3cr)<\/div>\n<\/div>\n<\/div>\n<\/div>\n

COURSE INSTRUCTORS:\u00a0<\/strong>Clint Makino, Travis Rotterman, Venetia Zachariou<\/p>\n

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GMS PM 610: Professional Success Skills<\/h4>
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The Professionalism and Skills for Success course is comprised of weekly workshop style sessions that will allow students to learn and apply best practices in professional behavior, success skills for the classroom and workplace, networking, and interviewing skills. Students will be assessed on their thoughtfulness in self-reflections as well as contributions to group projects, and individual assignments. (2cr)<\/p>\n

COURSE INSTRUCTOR: <\/strong>Kate Carnevale<\/p>\n

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GMS PM 620: Foundations in Life Sciences<\/h4>
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The Foundations in Life Sciences course is comprised of weekly lectures on topics related to the review of biochemistry, molecular and cellular biology, physiology and pharmacology principles. Students will be expected to be prepared to participate in class discussions, applications activities, readings, and be regularly quizzed and examined on key topics in the course. (3cr)<\/p>\n

COURSE INSTRUCTOR: <\/strong>Kate Carnevale<\/p>\n

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GMS PM 630: Topics in Drug Discovery<\/h4>
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The Drug Discovery Course is comprised of weekly lectures on topics related to an advanced analysis of the bench-bedside process involved in drug discovery. This includes an in-depth analysis of mechanisms underpinning selected diseases, the identification of therapeutic targets and novel therapeutics.\u00a0Students will be expected to participate in class discussions, readings, and be regularly quizzed and examined on key topics in the course. Finally, students will be expected to give a short talk on a therapeutic of their choice, the disease(s) that the therapeutic is intended to treat, and mechanisms underlying the drug action. This course is designed to provide a comprehensive view of technical concepts, and the application of pharmacological principles in drug target identification to drug development. Concrete examples of mechanism-based novel therapeutic targets and treatments will be described and discussed throughout the course. The individual student presentations provide a unique opportunity for applying course information to understanding disease-treatments that are in-use and drugs that are in the developmental pipeline.\u00a0\u00a0 Each student will present on specific marketed drugs of their choice, the mechanism-based rationale for treatment and adverse effects and treatment success. Throughout the course, relevant research publications will be discussed with active student participation.\u00a0(3cr)<\/span><\/p>\n

COURSE INSTRUCTOR: <\/strong>Kate Carnevale<\/p>\n

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GMS PM 640: Modern Research Methods<\/h4>
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The Modern Research Methods course is comprised of didactic lectures, labs, and an applied project illuminating concepts in macromolecular structure and analysis important for pharmacologists. The modules of the course cover an introduction to biophysical and biochemical experimental methods for analysis of macromolecular structure and function, and quantitative binding assays. After completing the course, learners will be able to describe the principles of the experimental techniques, identify their applications, advantages and limitations<\/span>, and to select the assays that are most appropriate for answering specific practical questions. (3cr)<\/p>\n

COURSE INSTRUCTORS: <\/strong>Kate Carnevale<\/p>\n

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GMS PM 650: Human Systems Physiology and Pharmacology<\/h4>
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The Human Systems Physiology & Pharmacology course is comprised of didactic lectures and scenario-based application exercises illuminating concepts in molecular physiology and pharmacology at the organ system level. The modules of the course cover an introduction to neurophysiology and pharmacology, and a deeper evaluation of cardiac, pulmonary, renal, gastrointestinal, endocrine and multisystem Physiology & Pharmacology topics. After completing the course, learners will be able to identify key physiological molecular targets and systemic mechanisms responsible for pharmacological outcomes throughout the human body. (4cr)<\/p>\n

COURSE INSTRUCTORS: <\/strong>Kate Carnevale<\/p>\n

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GMS PM 660: Advance Research Methods<\/h4>
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The Advanced Research Methods course is comprised of seven two-week modules. Each module focuses on a specific experimental method and consists of didactic lectures and labs, aimed at gaining both knowledge and hands-on experience. After completing the course, learners will be able to describe the principles of the experimental techniques, identify their applications, advantages and limitations, and perform analyses. (3cr)<\/p>\n

COURSE INSTRUCTORS: <\/strong>Kate Carnevale<\/p>\n

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GMS PM 670: Innovations in Pharmacology<\/h4>
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The Innovations in Pharmacology course is comprised of didactic lectures on novel concepts and methodologies with great impact on therapeutics, followed by in class discussions. The course includes RNA targeting drugs, nanobodies and biased signaling approaches modulating responses of G protein coupled receptors, as well as drugs targeting ubiquitination and chromatin complexes. (2cr)<\/p>\n

COURSE INSTRUCTORS: <\/strong>Kate Carnevale<\/p>\n

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GMS PM 680: Pharmacology Capstone Seminar<\/h4>
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The Pharmacology Capstone Seminar course is a hands-on course that includes both special seminars and workshop to guide students in (1) the design of high-quality scientific investigations (2) analysis, interpretation and reporting of scientific data, and (3) effective communication of scientific findings in oral and written formats. This course prepares students for independent, mentor-supervised pharmacology research, and integrates knowledge and skills acquired during coursework to prepare students for research and development for professional roles in the biopharmaceutical industry, government, academia and others. (2cr)<\/p>\n

COURSE INSTRUCTORS: <\/strong>Kate Carnevale<\/p>\n

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