{"id":8205,"date":"2023-01-25T15:26:21","date_gmt":"2023-01-25T20:26:21","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/genetics\/?p=8205"},"modified":"2023-06-02T09:57:35","modified_gmt":"2023-06-02T13:57:35","slug":"dr-farrers-radio-interview-siriusxm-doctor-radios-internal-medicine-show-hosted-by-dr-ira-breite-nyu-langone-health","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/genetics\/2023\/01\/25\/dr-farrers-radio-interview-siriusxm-doctor-radios-internal-medicine-show-hosted-by-dr-ira-breite-nyu-langone-health\/","title":{"rendered":"Dr. Farrer&#8217;s Radio Interview SiriusXM-Doctor Radio\u2019s\u00a0Internal Medicine\u00a0show hosted by Dr. Ira Breite (NYU Langone Health)"},"content":{"rendered":"<p>January 9, 2023, Dr. Farrer and Dr. Subramanian were <strong><u>f<\/u><u>eatured guest<\/u>s<\/strong>\u00a0on SiriusXM-Doctor Radio\u2019s\u00a0<em>Internal Medicine<\/em>\u00a0show hosted by Dr. Ira Breite (NYU Langone Health, gastroenterologist &amp; Clinical Associate Professor of Medicine).<\/p>\n<p>The talk discussed the recent study on the relationship between age-related macular degeneration as a risk factor for COVID-19 infection and severe disease.<\/p>\n<p><img src=\"https:\/\/www.bumc.bu.edu\/busm\/files\/2015\/06\/Lindsay-Farrer-1.jpg\" alt=\"Headshot of Lindsay Farrer\" \/><\/p>\n<p>Age-Related Macular Degeneration a Risk factor for Covid-10 Infection<\/p>\n<p>Recent evidence has emerged to suggest that age-related macular degeneration (AMD) is a clinical risk factor for increased risk for infection and mortality. AMD has been reported to confer higher risk of severe complications of SARS-CoV-2 infection, including respiratory failure and death (25 percent), a risk which is higher than Type 2 diabetes (21 percent) and obesity (13 percent).<\/p>\n<p>Considering these observations, researchers from Boston University Chobanian &amp; Avedisian School of Medicine hypothesized that AMD and COVID-19 share common genetic risk factors and designed and executed a\u00a0<a href=\"https:\/\/www.mdpi.com\/2077-0383\/12\/1\/109\">study<\/a>\u00a0that identified a novel association of the two diseases with variants in the PDGFB gene. This gene encodes a platelet derived growth factor (PDGF) which has a role in the formation of new blood vessels and is involved in the abnormal blood vessel changes that occur in AMD. They also found that more severe COVID-19 outcomes were associated with AMD likely arising from genetic predisposition to dysfunction involving complement proteins, as well as with a higher level of PDGF in blood serum.<\/p>\n<p>\u201cOur findings add to the body of evidence for the increased risk of infection and mortality from COVID-19 among AMD patients. Our analysis lends credence to previously reported clinical studies that found those with AMD have a higher risk for COVID-19 infection and severe disease, and that this increased risk may have a genetic basis,\u201d explained co-corresponding author\u00a0<a href=\"https:\/\/profiles.bu.edu\/Lindsay.Farrer\">Lindsay A. Farrer<\/a>, PhD, chief of biomedical genetics. <a href=\"https:\/\/www.bumc.bu.edu\/busm\/2023\/01\/03\/age-related-macular-degeneration-a-risk-factor-for-covid-19-infection\/#:~:text=School%20of%20Medicine-,Age%2DRelated%20Macular%20Degeneration%20a%20Risk%20Factor%20for%20COVID%2D19,risk%20for%20infection%20and%20mortality\">Read more here<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>January 9, 2023, Dr. Farrer and Dr. Subramanian were featured guests\u00a0on SiriusXM-Doctor Radio\u2019s\u00a0Internal Medicine\u00a0show hosted by Dr. Ira Breite (NYU Langone Health, gastroenterologist &amp; Clinical Associate Professor of Medicine). The talk discussed the recent study on the relationship between age-related macular degeneration as a risk factor for COVID-19 infection and severe disease. Age-Related Macular Degeneration [&hellip;]<\/p>\n","protected":false},"author":19517,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/posts\/8205"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/users\/19517"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/comments?post=8205"}],"version-history":[{"count":3,"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/posts\/8205\/revisions"}],"predecessor-version":[{"id":8247,"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/posts\/8205\/revisions\/8247"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/media?parent=8205"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/categories?post=8205"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/genetics\/wp-json\/wp\/v2\/tags?post=8205"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}