{"id":3157,"date":"2024-11-21T07:30:46","date_gmt":"2024-11-21T12:30:46","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/fhs-bap\/?p=3157"},"modified":"2024-11-21T07:30:50","modified_gmt":"2024-11-21T12:30:50","slug":"asian-cohort-for-alzheimers-disease-acad-pilot-study-on-genetic-and-non-genetic-risk-factors-for-alzheimers-disease-among-asian-americans-and-canadian","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/fhs-bap\/2024\/11\/21\/asian-cohort-for-alzheimers-disease-acad-pilot-study-on-genetic-and-non-genetic-risk-factors-for-alzheimers-disease-among-asian-americans-and-canadian\/","title":{"rendered":"Asian Cohort for Alzheimer&#8217;s Disease (ACAD) pilot study on genetic and non-genetic risk factors for Alzheimer&#8217;s disease among Asian Americans and Canadian"},"content":{"rendered":"<h2 class=\"title\">Abstract<\/h2>\n<div class=\"abstract-content selected\" id=\"eng-abstract\">\n<p><strong class=\"sub-title\">Introduction:<span>\u00a0<\/span><\/strong>Clinical research in Alzheimer&#8217;s disease (AD) lacks cohort diversity despite being a global health crisis. The Asian Cohort for Alzheimer&#8217;s Disease (ACAD) was formed to address underrepresentation of Asians in research, and limited understanding of how genetics and non-genetic\/lifestyle factors impact this multi-ethnic population.<\/p>\n<p><strong class=\"sub-title\">Methods:<span>\u00a0<\/span><\/strong>The ACAD started fully recruiting in October 2021 with one central coordination site, eight recruitment sites, and two analysis sites. We developed a comprehensive study protocol for outreach and recruitment, an extensive data collection packet, and a centralized data management system, in English, Chinese, Korean, and Vietnamese.<\/p>\n<p><strong class=\"sub-title\">Results:<span>\u00a0<\/span><\/strong>ACAD has recruited 606 participants with an additional 900 expressing interest in enrollment since program inception.<\/p>\n<p><strong class=\"sub-title\">Discussion:<span>\u00a0<\/span><\/strong>ACAD&#8217;s traction indicates the feasibility of recruiting Asians for clinical research to enhance understanding of AD risk factors. ACAD will recruit &gt; 5000 participants to identify genetic and non-genetic\/lifestyle AD risk factors, establish blood biomarker levels for AD diagnosis, and facilitate clinical trial readiness.<\/p>\n<p><strong class=\"sub-title\">Highlights:<span>\u00a0<\/span><\/strong>The Asian Cohort for Alzheimer&#8217;s Disease (ACAD) promotes awareness of under-investment in clinical research for Asians. We are recruiting Asian Americans and Canadians for novel insights into Alzheimer&#8217;s disease. We describe culturally appropriate recruitment strategies and data collection protocol. ACAD addresses challenges of recruitment from heterogeneous Asian subcommunities. We aim to implement a successful recruitment program that enrolls across three Asian subcommunities.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38215053\/\">Read More<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Abstract Introduction:\u00a0Clinical research in Alzheimer&#8217;s disease (AD) lacks cohort diversity despite being a global health crisis. The Asian Cohort for Alzheimer&#8217;s Disease (ACAD) was formed to address underrepresentation of Asians in research, and limited understanding of how genetics and non-genetic\/lifestyle factors impact this multi-ethnic population. Methods:\u00a0The ACAD started fully recruiting in October 2021 with one [&hellip;]<\/p>\n","protected":false},"author":22858,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[15,59,60,61,25,62,63],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/posts\/3157"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/users\/22858"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/comments?post=3157"}],"version-history":[{"count":1,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/posts\/3157\/revisions"}],"predecessor-version":[{"id":3158,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/posts\/3157\/revisions\/3158"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/media?parent=3157"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/categories?post=3157"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/tags?post=3157"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}