{"id":112,"date":"2021-08-20T11:19:07","date_gmt":"2021-08-20T11:19:07","guid":{"rendered":"https:\/\/realysys.co.uk\/projects\/wp-bap\/?page_id=112"},"modified":"2024-07-09T11:39:48","modified_gmt":"2024-07-09T15:39:48","slug":"brain-tissue-repository","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/fhs-bap\/research\/brain-tissue-repository\/","title":{"rendered":"Brain Tissue Repository"},"content":{"rendered":"\r\n<p class=\"has-text-align-center contain-large\" style=\"text-align: left;\">This Core, formally established in 1997, is co-led by Ann McKee, MD, and Thor Stein, MD, PhD, and carefully characterizes and performs neuropathological examination of brains obtained through the\u00a0Brain Donation Program.<\/p>\r\n\r\n<p class=\"has-text-align-center contain-large\" style=\"text-align: left;\">They use digital and biochemical quantification to provide objective and precise measures of neurodegenerations including amyloid and tau pathology as well as traditional pathological and semi-quantitative measures.<\/p>\r\n\r\n<div style=\"overflow: hidden;\">\r\n<p style=\"text-align: left;\"><strong><img loading=\"lazy\" src=\"\/fhs-bap\/files\/2023\/06\/Capture.png\" alt=\"\" width=\"405\" height=\"193\" class=\"alignleft wp-image-2598 \" srcset=\"https:\/\/www.bumc.bu.edu\/fhs-bap\/files\/2023\/06\/Capture.png 964w, https:\/\/www.bumc.bu.edu\/fhs-bap\/files\/2023\/06\/Capture-636x303.png 636w, https:\/\/www.bumc.bu.edu\/fhs-bap\/files\/2023\/06\/Capture-768x366.png 768w\" sizes=\"(max-width: 405px) 100vw, 405px\" \/><\/strong><\/p>\r\n<p style=\"text-align: left;\"><strong>Digital Pathology Library \u2013 cellular phenotypes<\/strong><\/p>\r\n<p style=\"text-align: left;\">Quantitated the density of immunopositive cells (IBA-1+ microglia, CD68+ microglia, AT8+ neurofibrillary tangles) within the sulcal depth of dorsolateral frontal cortex using the Aperio ScanScope.<\/p>\r\n<\/div>\r\n<div style=\"overflow: hidden;\">\r\n<p style=\"text-align: left;\"><img loading=\"lazy\" src=\"\/fhs-bap\/files\/2023\/05\/storage-e1684775798771.jpg\" alt=\"\" width=\"405\" height=\"193\" class=\"alignleft wp-image-2410 \" srcset=\"https:\/\/www.bumc.bu.edu\/fhs-bap\/files\/2023\/05\/storage-e1684775798771.jpg 500w, https:\/\/www.bumc.bu.edu\/fhs-bap\/files\/2023\/05\/storage-e1684775798771-496x238.jpg 496w\" sizes=\"(max-width: 405px) 100vw, 405px\" \/> <strong>On Campus Server Storage<\/strong><\/p>\r\n<p style=\"text-align: left;\">Have dedicated 100TB of server space for image storage. No cap on upgrading storage space when needed. Fully backed up. 1GB connection line for fast data transfer.<\/p>\r\n<\/div>\r\n<p><a href=\"https:\/\/www.bumc.bu.edu\/fhs-bap\/program-cores\/\">Back to Program Cores<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>This Core, formally established in 1997, is co-led by Ann McKee, MD, and Thor Stein, MD, PhD, and carefully characterizes and performs neuropathological examination of brains obtained through the\u00a0Brain Donation Program. They use digital and biochemical quantification to provide objective and precise measures of neurodegenerations including amyloid and tau pathology as well as traditional pathological [&hellip;]<\/p>\n","protected":false},"author":1130,"featured_media":0,"parent":121,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"page-templates\/no-sidebars.php","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/pages\/112"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/users\/1130"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/comments?post=112"}],"version-history":[{"count":50,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/pages\/112\/revisions"}],"predecessor-version":[{"id":2601,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/pages\/112\/revisions\/2601"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/pages\/121"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/fhs-bap\/wp-json\/wp\/v2\/media?parent=112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}