\n
![\"Mouse](\"\/devbio\/files\/2010\/01\/Slide1.jpg\")
<\/p>\nAlbrecht Lab<\/strong><\/a>, <\/strong>Genetics, Department of Medicine <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n <\/em><\/p>\n Cardoso Lab<\/strong><\/span><\/span><\/a>,<\/strong> <\/em><\/strong><\/span>Pulmonary Center, Department of Medicine<\/span><\/span> Cohen Lab<\/strong><\/span><\/a>,<\/span> <\/span>Nephrology, Department of Medicine<\/span> Cotanche Lab<\/strong><\/span><\/a>, <\/span>Department of Otolarangology<\/span> Dominguez Lab<\/strong><\/span><\/a>,\u00a0Hematology and Oncology, Department of Medicine<\/span> Gerstenfeld Lab<\/strong><\/span><\/a>, <\/strong>Department of\u00a0Orthopedic Surgery<\/span> Hsu Lab<\/strong><\/span><\/a>,\u00a0Hematology and Oncology, Department of Medicine<\/span> Kotton Lab<\/strong><\/span><\/a>,\u00a0Pulmonary Center, Department of Medicine Kukuruzinska Lab<\/strong><\/span><\/a>,\u00a0Department of Molecular and Cell Biology<\/span> J. Lu<\/strong><\/span><\/a> Lab<\/strong><\/span><\/a>,\u00a0Pulmonary Center, Department of Medicine<\/span> W. Lu Lab<\/strong><\/span><\/a>,\u00a0Nephrology, Department of Medicine Mostoslavsky Lab<\/strong><\/span><\/a>,\u00a0Gastroenterology, Department of Medicine<\/span> Navarro Lab<\/strong><\/span><\/a>,\u00a0Genetics, Department of Medicine Ramirez Lab<\/strong><\/span><\/a>,\u00a0Pulmonary Center, Department of Medicine Seldin Lab<\/strong><\/span><\/a>,\u00a0Hematology and Oncology, Department of Medicine Symes Lab<\/strong><\/span><\/a>,\u00a0Department of Biochemistry Ai Lab, Pulmonary Center, Department of Medicine Albrecht Lab, Genetics, Department of Medicine Basic science focus: sex determination, gonad differentiation, cell fate determination, organogenesis Clinical relevance: ovarian cancer, infertility, premature ovarian insufficiency, birth defects Cardoso Lab, Pulmonary Center, Department of Medicine Cohen Lab, Nephrology, Department of Medicine Cotanche Lab, Department of Otolarangology Dominguez Lab,\u00a0Hematology and […]<\/p>\n","protected":false},"author":1326,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"closed","ping_status":"open","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/devbio\/wp-json\/wp\/v2\/pages\/689"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/devbio\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/devbio\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/devbio\/wp-json\/wp\/v2\/users\/1326"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/devbio\/wp-json\/wp\/v2\/comments?post=689"}],"version-history":[{"count":83,"href":"https:\/\/www.bumc.bu.edu\/devbio\/wp-json\/wp\/v2\/pages\/689\/revisions"}],"predecessor-version":[{"id":803,"href":"https:\/\/www.bumc.bu.edu\/devbio\/wp-json\/wp\/v2\/pages\/689\/revisions\/803"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/devbio\/wp-json\/wp\/v2\/media?parent=689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nBasic science focus: sex determination, gonad differentiation, cell fate determination, organogenesis<\/span><\/span>
\n<\/span> Clinical relevance:<\/span><\/span> <\/span><\/span> <\/span>ovarian cancer, infertility, premature ovarian insufficiency, birth defects<\/span><\/span>
\n<\/em> ![\"Fly](\"\/devbio\/files\/2010\/01\/Slide3.jpg\")
![\"Chick](\"\/devbio\/files\/2010\/01\/Slide4.jpg\")
<\/em><\/em><\/p>\n
\n <\/p>\n
\n<\/p>\n
\n <\/p>\n
\n Basic science focus:<\/span><\/span> <\/span>heart morphogenesis, organogenesis, WNT signaling, dorsal axis formation, cell fate determination<\/span><\/span>
\n<\/span> Clinical relevance:<\/span><\/span> congenital heart disease, breast and colon cancer<\/span>
\n![\"Frog](\"\/devbio\/files\/2010\/01\/Slide2.jpg\")
<\/p>\n
\n<\/p>\n
\n Basic science focus: epithelial morphogenesis, intracellular trafficking of proteins and nucleic acids, cell-stromal interaction
\nClinical relevance: tumor formation<\/span>
\n <\/p>\n
\nBasic science focus: stem cell biology, reprogramming, lung epithelial lineage specification
\nClinical relevance: acute lung injury\/ARDS, emphysema, regenerative medicine<\/span>
\n<\/p>\n
\n<\/p>\n
\n<\/p>\n
\nBasic science focus: kidney and urinary tract development, Slit-Robo signaling pathway, mouse models of renal genetic disorders
\nClinical relevance: congenital anomalies of the kidney and urinary tract (CAKUT), vesicoureteral reflux (VUR), human kidney gene mutations<\/span>
\n<\/p>\n
\n<\/p>\n
\nBasic science focus: cell polarity, molecular motor transport, cell fate determination, piRNAs
\nClinical relevance: epithelial cancer, birth defects, neurodegenerative diseases
\n<\/span> <\/span><\/p>\n
\n<\/span> <\/span><\/p>\n
\n<\/span> <\/span><\/p>\n
\nBasic science focus: cell motility, gastrulation, notochord morphogenesis, platelet-derived growth factor signaling
\nClinical relevance: cancer metastasis, skeletal birth defects
\n<\/span> <\/span><\/p>\n<\/a>DBRG labs use fruit flies, frogs, chicks, and mice as model systems to study many aspects of development<\/span><\/h5>\n<\/div>\n","protected":false},"excerpt":{"rendered":"