{"id":196,"date":"2011-05-30T23:41:46","date_gmt":"2011-05-31T03:41:46","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/csdl\/?page_id=196"},"modified":"2015-08-29T10:31:31","modified_gmt":"2015-08-29T14:31:31","slug":"sirt1-and-er-stress-in-type-2-diabetes","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/csdl\/research-summary-2\/sirt1-and-er-stress-in-type-2-diabetes\/","title":{"rendered":"SIRT1, ER Stress, and Type 2 Diabetes"},"content":{"rendered":"<p>Dr. Mengwei Zang&#8217;s presentations in ADA webcasts\u00a0 (<a href=\"http:\/\/professional.diabetes.org\/Adv_SearchResult.aspx?kwd=AMPK%20and%20Zang&amp;sr=pup&amp;ResType=ALL&amp;typ=10&amp;adv=False\">2009<\/a>)<\/p>\n<p><strong>Hepatic Overexpression of SIRT1 Ameliorates Hepatic Steatosis by Suppressing mTORC1<\/strong><strong> <\/strong><strong> Activation and ER Stress in ob\/ob Mice<\/strong><\/p>\n<p><strong><strong><a href=\"\/csdl\/files\/2011\/05\/2011_Dec_25_Web-design12-50.jpg\"><img loading=\"lazy\" class=\"aligncenter size-medium wp-image-352\" title=\"Slide 1\" src=\"\/csdl\/files\/2011\/05\/2011_Dec_25_Web-design12-50-400x300.jpg\" alt=\"Slide 1\" height=\"300\" width=\"400\" srcset=\"https:\/\/www.bumc.bu.edu\/csdl\/files\/2011\/05\/2011_Dec_25_Web-design12-50-400x300.jpg 400w, https:\/\/www.bumc.bu.edu\/csdl\/files\/2011\/05\/2011_Dec_25_Web-design12-50.jpg 500w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><\/a><\/strong><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><strong>The Proposed model by which Hepatic Overexpression of SIRT1 in Mice Attenuates Endoplasmic Reticulum Stress and Insulin Resistance in the Liver<\/strong><\/p>\n<p><strong><a href=\"\/csdl\/files\/2011\/05\/2011_Dec_25_Web-design-11-50.jpg\"><img loading=\"lazy\" class=\"aligncenter size-medium wp-image-354\" title=\"Slide 1\" src=\"\/csdl\/files\/2011\/05\/2011_Dec_25_Web-design-11-50-400x300.jpg\" alt=\"Slide 1\" height=\"300\" width=\"400\" srcset=\"https:\/\/www.bumc.bu.edu\/csdl\/files\/2011\/05\/2011_Dec_25_Web-design-11-50-400x300.jpg 400w, https:\/\/www.bumc.bu.edu\/csdl\/files\/2011\/05\/2011_Dec_25_Web-design-11-50.jpg 500w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><\/a><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><strong> <\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Mengwei Zang&#8217;s presentations in ADA webcasts\u00a0 (2009) Hepatic Overexpression of SIRT1 Ameliorates Hepatic Steatosis by Suppressing mTORC1 Activation and ER Stress in ob\/ob Mice &nbsp; The Proposed model by which Hepatic Overexpression of SIRT1 in Mice Attenuates Endoplasmic Reticulum Stress and Insulin Resistance in the Liver &nbsp;<\/p>\n","protected":false},"author":1275,"featured_media":0,"parent":133,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/csdl\/wp-json\/wp\/v2\/pages\/196"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/csdl\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/csdl\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/csdl\/wp-json\/wp\/v2\/users\/1275"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/csdl\/wp-json\/wp\/v2\/comments?post=196"}],"version-history":[{"count":19,"href":"https:\/\/www.bumc.bu.edu\/csdl\/wp-json\/wp\/v2\/pages\/196\/revisions"}],"predecessor-version":[{"id":443,"href":"https:\/\/www.bumc.bu.edu\/csdl\/wp-json\/wp\/v2\/pages\/196\/revisions\/443"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/csdl\/wp-json\/wp\/v2\/pages\/133"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/csdl\/wp-json\/wp\/v2\/media?parent=196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}