{"id":1226,"date":"2016-04-01T15:19:09","date_gmt":"2016-04-01T19:19:09","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/compbiomed\/?page_id=1226"},"modified":"2021-03-22T12:15:40","modified_gmt":"2021-03-22T16:15:40","slug":"david-jenkins","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/compbiomed\/david-jenkins\/","title":{"rendered":"David Jenkins"},"content":{"rendered":"<p><strong><a href=\"\/compbiomed\/files\/2016\/09\/David-Jenkins-blur.png\"><img loading=\"lazy\" width=\"131\" height=\"160\" class=\" wp-image-1476 alignright\" alt=\"David Jenkins - blur\" src=\"\/compbiomed\/files\/2016\/09\/David-Jenkins-blur.png\" \/><\/a>Ph.D. Candidate, Bioinformatics, BUSM<br \/>\nJohnson Lab<\/strong><\/p>\n<h4>Education<\/h4>\n<p>Sc.B.\u00a0Computational Biology, Brown University, Providence, RI, 2011<\/p>\n<h4>Contact Information<\/h4>\n<p><strong>Email:<\/strong> dfj@bu.edu<\/p>\n<p>github.com\/dfjenkins3<\/p>\n<h4>Research Interests<\/h4>\n<p><strong>Pathway Activity Analysis in Cancer RNA-Seq Data<\/strong><\/p>\n<p>My project involves creating and applying computational tools that analyze cancer data at a pathway activation level. The genetic background of cancer is complex and can involve multiple signaling pathways. By identifying active oncogenic pathways, and the interactions between them, we are gaining a better understanding of the genetics of cancer, and are exploring ways to match cancer patients with the most effective drugs for them.<\/p>\n<h4><strong>Publications<\/strong><\/h4>\n<p>Brady, Samuel W., Jasmine A. McQuerry, Yi Qiao, Stephen R. Piccolo, Gajendra Shrestha, <strong>David F. Jenkins<\/strong>, Ryan M. Layer, et al. 2017. \u201cCombating Subclonal Evolution of Resistant Cancer Phenotypes.\u201d <em>Nature Communications<\/em> 8 (1): 883. <a href=\"http:\/\/dx.doi.org\/10.1038\/s41467-017-01174-3\">10.1038\/s41467-017-01174-3<\/a><\/p>\n<p>Goldberg, Lisa R., Stacey L. Kirkpatrick, Neema Yazdani, Kimberly P. Luttik, Olga A. Lacki, R. Keith Babbs, <strong>David F. Jenkins<\/strong>, W. Evan Johnson, and Camron D. Bryant. 2017. \u201cCasein Kinase 1-Epsilon Deletion Increases Mu Opioid Receptor-Dependent Behaviors and Binge Eating.\u201d <em>Genes, Brain, and Behavior<\/em>, June. <a href=\"http:\/\/dx.doi.org\/10.1111\/gbb.12397\">10.1111\/gbb.12397<\/a><\/p>\n<p>Rahman, Mumtahena\u2020, Shelley M. MacNeil\u2020, <strong>David F. Jenkins<\/strong>\u2020, Gajendra Shrestha, Sydney R. Wyatt, Jasmine A. McQuerry, Stephen R. Piccolo, Laura M. Heiser, Joe W. Gray, W. Evan Johnson and Andrea H. Bild. 2017. \u201cActivity of Distinct Growth Factor Receptor Network Components in Breast Tumors Uncovers Two Biologically Relevant Subtypes.\u201d <em>Genome Medicine<\/em> 9 (1): 40. <a href=\"http:\/\/dx.doi.org\/10.1186\/s13073-017-0429-x\">10.1186\/s13073-017-0429-x<\/a><\/p>\n<p>\u2020 Contributed equally<\/p>\n<p>Ahdesm\u00e4ki, Miika J., Brad A. Chapman, Pablo Cingolani, Oliver Hofmann, Aleksandr Sidoruk, Zhongwu Lai, Gennadii Zakharov, Mikhail Rodichenko, Mikhail Alperovich, <strong>David Jenkins<\/strong>, T. Hedley Carr, Daniel Stetson, Brian Dougherty, J. Carl Barrett, and Justin H. Johnson. 2017. \u201cPrioritisation of Structural Variant Calls in Cancer Genomes.\u201d <em>PeerJ<\/em> 5 (April): e3166. <a href=\"http:\/\/dx.doi.org\/10.7717\/peerj.3166\">10.7717\/peerj.3166<\/a><\/p>\n<p>Kirkpatrick, Stacey L., Lisa R. Goldberg, Neema Yazdani, R. Keith Babbs, Jiayi Wu, Eric R. Reed, <strong>David F. Jenkins<\/strong>, Amanda F. Bolgioni, Kelsey I. Landaverde, Kimberly P. Luttik, Karen S. Mitchell, Vivek Kumar, W. Evan Johnson, Megan K. Mulligan, Pietro Cottone, and Camron D. Bryant. 2017. \u201cCytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating.\u201d <em>Biological Psychiatry<\/em> 81 (9): 757\u201369. <a href=\"http:\/\/dx.doi.org\/10.1016\/j.biopsych.2016.10.021\">10.1016\/j.biopsych.2016.10.021<\/a><\/p>\n<p>Shrestha, Gajendra, Shelley M. MacNeil, Jasmine A. McQuerry, <strong>David F. Jenkins<\/strong>, Sunil Sharma, and Andrea H. Bild. 2016. \u201cThe Value of Genomics in Dissecting the RAS-Network and in Guiding Therapeutics for RAS-Driven Cancers.\u201d <em>Seminars in Cell &amp; Developmental Biology<\/em> 58 (October): 108\u201317. <a href=\"http:\/\/dx.doi.org\/10.1016\/j.semcdb.2016.06.012\">10.1016\/j.semcdb.2016.06.012<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ph.D. Candidate, Bioinformatics, BUSM Johnson Lab Education Sc.B.\u00a0Computational Biology, Brown University, Providence, RI, 2011 Contact Information Email: dfj@bu.edu github.com\/dfjenkins3 Research Interests Pathway Activity Analysis in Cancer RNA-Seq Data My project involves creating and applying computational tools that analyze cancer data at a pathway activation level. The genetic background of cancer is complex and can involve [&hellip;]<\/p>\n","protected":false},"author":11679,"featured_media":0,"parent":0,"menu_order":19,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/compbiomed\/wp-json\/wp\/v2\/pages\/1226"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/compbiomed\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/compbiomed\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/compbiomed\/wp-json\/wp\/v2\/users\/11679"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/compbiomed\/wp-json\/wp\/v2\/comments?post=1226"}],"version-history":[{"count":8,"href":"https:\/\/www.bumc.bu.edu\/compbiomed\/wp-json\/wp\/v2\/pages\/1226\/revisions"}],"predecessor-version":[{"id":2090,"href":"https:\/\/www.bumc.bu.edu\/compbiomed\/wp-json\/wp\/v2\/pages\/1226\/revisions\/2090"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/compbiomed\/wp-json\/wp\/v2\/media?parent=1226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}