{"id":5365,"date":"2012-08-07T14:20:34","date_gmt":"2012-08-07T18:20:34","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/care\/?page_id=5365"},"modified":"2025-10-02T11:28:02","modified_gmt":"2025-10-02T15:28:02","slug":"vip-study","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/care\/research-studies\/vip-study\/","title":{"rendered":"VIP Study"},"content":{"rendered":"<h3><strong>\u00a0<\/strong><\/h3>\n<h3><strong>Principal Investigator <\/strong><\/h3>\n<p style=\"padding-left: 30px;\"><a href=\"https:\/\/www.bumc.bu.edu\/care\/faculty\/judith-tsui\/\">Judith Tsui, MD, MPH<\/a><\/p>\n<h3><strong>Key Personnel <\/strong><\/h3>\n<p style=\"padding-left: 30px;\"><a href=\"..\/faculty\/jeffrey-samet\/\">Jeffrey Samet, MD, MA, MPH<\/a>, Mentor<\/p>\n<h3><strong>Contact<\/strong><\/h3>\n<p style=\"padding-left: 30px;\">617-414-6905<\/p>\n<h3><strong>Staff<br \/>\n<\/strong><\/h3>\n<p style=\"padding-left: 30px;\">Marlene Alcorn, Research Assistant<\/p>\n<h3><strong>Grant Abstract<\/strong><\/h3>\n<p>The Viral Infections and Pain in Substance Users (VIPS) Study at Boston Medical Center will explore the hypotheses that infection with hepatitis C virus (HCV) is associated with: 1) hypersensitivity to pain under experimental conditions and 2) clinical pain.\u00a0 The study will recruit a cohort of 120 opioid dependent patients on buprenorphine or methadone: 40 HCV+\/HIV-, 40 HCV+\/HIV+ and 40 HCV-\/HIV-controls.\u00a0 Participants will undergo the following experimental testing: 1) the cold-pressor test to assess cold pain tolerance 2) mechanical stimulus to test mechanical pain thresholds and 3) repetitive pinprick to assess for temporal summation.\u00a0 The study will also collect data on pain and pain-related variables using a questionnaire and measure inflammatory cytokines from peripheral blood samples.<strong> <\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0 Principal Investigator Judith Tsui, MD, MPH Key Personnel Jeffrey Samet, MD, MA, MPH, Mentor Contact 617-414-6905 Staff Marlene Alcorn, Research Assistant Grant Abstract The Viral Infections and Pain in Substance Users (VIPS) Study at Boston Medical Center will explore the hypotheses that infection with hepatitis C virus (HCV) is associated with: 1) hypersensitivity to [&hellip;]<\/p>\n","protected":false},"author":5977,"featured_media":0,"parent":62,"menu_order":25,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/care\/wp-json\/wp\/v2\/pages\/5365"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/care\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/care\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/care\/wp-json\/wp\/v2\/users\/5977"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/care\/wp-json\/wp\/v2\/comments?post=5365"}],"version-history":[{"count":9,"href":"https:\/\/www.bumc.bu.edu\/care\/wp-json\/wp\/v2\/pages\/5365\/revisions"}],"predecessor-version":[{"id":8595,"href":"https:\/\/www.bumc.bu.edu\/care\/wp-json\/wp\/v2\/pages\/5365\/revisions\/8595"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/care\/wp-json\/wp\/v2\/pages\/62"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/care\/wp-json\/wp\/v2\/media?parent=5365"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}