{"id":207,"date":"2014-01-19T13:36:27","date_gmt":"2014-01-19T18:36:27","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/cardiograd\/?page_id=207"},"modified":"2018-08-08T12:17:46","modified_gmt":"2018-08-08T16:17:46","slug":"representative-publications-by-trainees","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/cardiograd\/representative-publications-by-trainees\/","title":{"rendered":"Representative Publications by Trainees"},"content":{"rendered":"

NIHMS Submission and ID Number<\/b><\/span>
\nFor Instructions click here:\u00a0NIHMSID number instructions<\/a><\/span><\/p>\n

Selected Representative Publications by Trainees in the past 10 years<\/em>:\u00a0<\/strong><\/p>\n

Eisenstein A, Carroll SH, Johnston-Cox H, Farb M, Gokce N, Ravid K. An Adenosine Receptor-Kr\u00fcppel-like Factor 4 Protein Axis Inhibits Adipogenesis. J Biol Chem. 2014 Jul 25;289(30):21071-21081. PMCID:PMC4110311<\/p>\n

Coughlan KA, Balon TW, Petrocelli R, Schultz V, Brandon A, Kraegen EW, Ruderman NB and Saha AK. Insulin Resistance due to Nutrient Excess: Multiple Mechanisms of AMPK Downregulation. PLoS One. 2015:10, e0127388 PMCID: PMC4440828<\/p>\n

Tanaka Y, Koido S, Xia J, Ohana M, Liu C, Cote GM<\/b>, Sawyer DB, Calderwood S, Gong J. Development of antigen-specific CD8+ CTL in MHC class I-deficient mice through CD4 to CD8 conversion.<\/i> J Immunol. 2004 Jun 15; 172(12): 7848-58. PMID: 15187169<\/p>\n

Kuramochi Y, Cote GM<\/b>, Guo X, Lebrasseur NK, Cui L, Liao R, Sawyer DB. Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta\/erbB4 signaling. <\/i>J Biol Chem. 2004 Dec 3; 279(49):51141-7. PMID: 15385548<\/p>\n

Miller TA, LeBrasseur NK, Cote GM<\/b>, Trucillo MP, Pimentel DR, Ido Y, Ruderman NB, Sawyer DB. Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes.<\/i> Biochem Biophys Res Commun. 2005 Oct 14; 336(1):309-15. PMID: 16126172<\/p>\n

Cote GM<\/b>, Miller TA, Lebrasseur NK, Kuramochi Y, Sawyer DB. Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro. Exp Cell Res. 2005 Nov 15; 311(1):135-46. PMID: 16185687<\/p>\n

Sethuraman M, McComb ME, Huang H, Huang S, Heibeck T<\/b>, Costello CE, Cohen RA. Isotope-coded affinity tag (ICAT) approach to redox proteomics: identification and quantitation of oxidant-sensitive cysteine thiols in complex protein mixtures.<\/i> J Proteome Res. 2004 Nov-Dec; 3(6):1228-33. PMID: 15595732<\/p>\n

Adachi T, Pimentel DR, Heibeck T<\/b>, Hou X, Lee YJ, Jiang B, Ido Y, Cohen RA. S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells.<\/i> J Biol Chem. 2004 Jul 9; 279(28):29857-62. PMID: 15123696<\/p>\n

Sethuraman M, McComb ME, Heibeck T<\/b>, Costello CE, Cohen RA. Isotope-coded affinity tag approach to identify and quantify oxidant-sensitive protein thiols.<\/i> Mol Cell Proteomics. 2004 Mar; 3(3):273-8. PMID: 14726493<\/p>\n

Pimentel DR, Adachi T, Ido Y, Heibeck T<\/b>, Jiang B, Lee Y, Melendez JA, Cohen RA, Colucci WS. Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive oxygen species-dependent Ras S-glutathiolation.<\/i> J Mol Cell Cardiol. 2006 Oct; 41(4):613-22. PMID: 16806262<\/p>\n

Nagata Y, Jones MR, Nguyen HG, McCrann DJ<\/b>, St Hilaire C, Schreiber BM, Hashimoto A, Inagaki M, Earnshaw WC, Todokoro K, Ravid K. Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle.<\/i> Exp Cell Res. 2005 May 1;305(2):277-91. PMID: 15817153<\/p>\n

YangUniv. D, McCrann<\/b>Univ. DJ<\/b>, Nguyen H, St. Hilaire C, DePinho RA, Jones MR, Ravid K. Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence.<\/i> (Univ.contributed equally) Aging Cell. 2007 Apr;6(2):257-60. Epub 2007 Feb 7. PMID: 17291294 (Univ.equal contributors)<\/p>\n

McCrann DJ<\/b>, Yezefski T, Nguyen HG, Papadantonakis N, Liu H, Wen Q, Crispino JD, Ravid K. Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid\/megakaryocytic lineage development in transgenic mice. Blood. 2008 Apr 15;111(8):4092-5. Epub 2008 Feb 1. PMCID: PMC2288720<\/p>\n

Yang D, Koupenova M, McCrann DJ<\/b>, Kopeikina KJ, Kagan HM, Schreiber BM, Ravid K. The A2b adenosine receptor protects against vascular injury. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):792-6. Epub 2008 Jan 9. PMCID: PMC2206615<\/p>\n

McCrann DJ<\/b>, Nguyen HG, Jones MR, Ravid K. Vascular smooth muscle cell polyploidy: an adaptive or maladaptive response? J Cell Physiol. 2008 Jun;215(3):588-92. Review.\u00a0PMID: 18181174 [PMC Journal – in process]<\/p>\n

Papadantonakis N, Makitalo M, McCrann DJ<\/b>, Liu K, Nguyen HG, Martin G, Patel-Hett S, Italiano JE, Ravid K. Direct visualization of the endomitotic cell cycle in living megakaryocytes: differential patterns in low and high ploidy cells. Cell Cycle. 2008 Aug;7(15):2352-6. Epub 2008 May 21. PMCID: PMC2861775<\/p>\n

McCrann DJ<\/b>, Eliades A, Makitalo M, Matsuno K, Ravid K. Differential expression of NADPH oxidases in megakaryocytes and their role in polyploidy. Blood. 2009 Aug 6;114(6):1243-9. PMCID: PMC2723018<\/p>\n

McCrann DJ<\/b>, Yang D, Chen H, Carroll S, Ravid K. Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy. Cell Cycle. 2009 Mar 15;8(6):902-8. PMCID: PMC2744814<\/p>\n

McCrann DJ<\/b>, Ravid K. Survivin localization during endomitosis of high ploidy mouse megakaryocytes. Blood. 2010 Sep 23;116(12):2192-3 PMCID: PMC2951860<\/p>\n

Voetsch B, Jin RC, Bierl C, Benke KS, Kenet G, Simioni P, Ottaviano F<\/b>, Damasceno BP, Annichino-Bizacchi JM, Handy DE, Loscalzo J. Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children. Stroke. 2007 Jan;38(1):41-9. Epub 2006 Nov 22. PMID: 17122425<\/p>\n

Ottaviano F<\/b>, Handy D, Loscalzo J.\u00a0 Overexpression and Purification of the Selenoprotein Plasma Glutathione Peroxidase. FASEB J: American Society for Biochemistry and Molecular Biology<\/i> Washington, DC, April 2007. [published abstract]<\/p>\n

Ottaviano FG<\/b>, Handy DE, Loscalzo J. Redox regulation in the extracellular environment. Circ J. 2008 Jan;72(1):1-16. Review. PMID: 18159092<\/p>\n

Ottaviano FG<\/b>, Tang SS, Handy DE, Loscalzo J. Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPx-3) in mammalian cells. Mol Cell Biochem. 2009 Jul;327(1-2):111-26. PMCID: PMC2693281<\/p>\n

Park K<\/b>, Csutora P, Peter K, Bolotina, VM. iPLA2-dependent activation of store-operated channels is crucial for agonist-induced Ca2+ influx and constriction in SMCs of cerebral arteries. FASEB J<\/i>; Phospholipase Meeting, Saxton River, VT, USA. 2006. [published abstract]<\/p>\n

Park K<\/b>, Csutora P, Peter K, Bolotina, VM. iPLA2-dependent activation of store-operated channels is crucial for agonist-induced Ca2+ influx and constriction in SMCs of cerebral arteries. FASEB J; SMC Meeting, Snowmass, CO, USA. 2006. [published abstract]<\/p>\n

Park KM<\/b>, Trucillo M, Serban N, Cohen RA, Bolotina VM. Role of iPLA2 and store-operated channels in agonist-induced Ca2+ influx and constriction in cerebral, mesenteric, and carotid arteries. Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1183-7. PMID: 18156193<\/p>\n

Csutora P, Peter K, Kilic H, Park KM<\/b>, Zarayskiy V, Gwozdz T, Bolotina VM. Novel role for STIM1 as a trigger for calcium influx factor production. J Biol Chem. 2008 May 23;283(21):14524-31. PMCID: PMC2386937<\/p>\n

Nagata Y, Jones MR, Nguyen HG, McCrann DJ, St.<\/b> Hilaire C<\/b>, Schreiber BM, Hashimoto A, Inagakid M, Earnshawe WC, Todokorob K et al: Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle.<\/i><\/p>\n

Experimental Cell Research 2005, 305:277-291. PMID: 15817153<\/p>\n

Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St. Hilaire C<\/b>, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD and Ravid K. The A2B adenosine receptor protects against inflammation and excessive vascular adhesion.<\/i> J Clin Invest. 2006. 116(7):1913-1923. PMID: 16823489<\/p>\n

Hazony Y, Lu J, St Hilaire C<\/b>, Ravid K. Hematopoietic gene promoters subjected to a group-combinatorial study of DNA samples: identification of a megakaryocytic selective DNA signature.\u00a0Nucleic Acids Res. 2006. 34(16):4416-28. Epub 2006 Aug 26. PMID: 16936310<\/p>\n

Yang D, McCrann DJ, Nguyen H, St. Hilaire C<\/b>, DePinho RA, Jones MR, Ravid K. Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence. Aging Cell. 2007 Apr; 6(2):257-60. Epub 2007 Feb 7. PMID: 17291294<\/p>\n

Hurtado PA, Vora S, Sume SS, Yang D, St. Hilaire C<\/b>, Guo Y, Palamakumbura AH, Schreiber BM, Ravid K, Trackman PC. Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation. Biochem Biophys Res Commun. 2008 Feb 1; 366(1):156-61. Epub 2007 Dec 3. PMID: 18060869<\/p>\n

St. Hilaire C<\/b>, Yang D, Schreiber BM, Ravid K. B-Myb regulates the A(2B) adenosine receptor in vascular smooth muscle cells. J Cell Biochem. 2008 Apr 15;103(6):1962-74. PMCID: PMC3303598<\/p>\n

St. Hilaire C<\/b>, Koupenova M, Carroll SH, Smith BD, Ravid K. TNF-alpha upregulates the A(2B) adenosine receptor gene: The role of NAD(P)H oxidase 4. Biochem Biophys Res Commun. 2008 Jul 19. [Epub ahead of print] PMCID: PMC2583397<\/p>\n

Nguyen HG, Makitalo M, Yang D, Chinnappan D, St Hilaire C<\/b>, Ravid K. Deregulated Aurora-B induced tetraploidy promotes tumorigenesis. FASEB J. 2009 Aug;23(8):2741-8. PMCID: PMC2717782<\/p>\n

Sullivan CP<\/b>, Seidl SE, Rich CB, Raymondjean M, Schreiber BM., 2010, Secretory phospholipase A2, group IIA is a novel serum amyloid A target gene: activation of smooth muscle cell expression by an interleukin-1 receptor-independent mechanism. J Biol Chem. 2010 Jan 1;285(1):565-75.\u00a0 PMCID: PMC2804205<\/p>\n

Zannis VI, Koukos G, Drosatos K, Vezeridis A<\/b>, Zanni EE, Kypreos KE, Chroni A. Discrete roles of apoA-I and apoE in the biogenesis of HDL species: lessons learned from gene transfer studies in different mouse models. Ann Med. 2008 Feb; 40 Suppl 1:14-28. Review. PMID: 18246469<\/p>\n

Vezeridis<\/b> AM, Chroni A, Zannis VI. Domains of apoE4 required for the biogenesis of apoE-containing HDL. Ann Med. 2011 Jun; 43(4): 302-11. PMCID: PMC3110089<\/p>\n

Yang D, Koupenova M<\/b>, McCrann DJ, Kopeikina KJ, Kagan HM, Schreiber BM, Ravid K. The A2b adenosine receptor protects against vascular injury. Proc Natl Acad Sci U S A. 2008 105(2):792-6. PMCID: PMC2206615<\/p>\n

St Hilaire C, Koupenova M<\/b>, Carroll SH, Smith BD, Ravid K. TNF-alpha upregulates the A(2B) adenosine receptor gene: The role of NAD(P)H oxidase 4. Biochem Biophys Res Commun. 2008 375(3): 292-296. PMCID: PMC2583397<\/p>\n

Yang D, Chen H, Koupenova M<\/b>, Carroll SH, Eliades A, Freedman JE, Toselli P, Ravid K. A new role for the A2b adenosine receptor in regulating platelet function. J Thromb Haemost. 2010 Apr;8(4):817-27.\u00a0PMID: 20102488<\/p>\n

Chen H, Koupenova M<\/b>, Yang D, Sume SS, Trackman PC, Ravid K. Regulation of MMP-9 expression by the A2b adenosine receptor and its dependency on TNF-\u03b1 signaling. Exp Hematol. 2011 May;39(5):525-30. Epub 2011 Feb 12. PMID: 21320567<\/p>\n

Koupenova M<\/b>, Johnston-Cox H, Vezeridis A, Gavras H, Yang D, Zannis V, Ravid K. A2b adenosine receptor regulates hyperlipidemia and atherosclerosis. Circulation. 2012 Jan 17;125(2):354-63. PMCID: PMC3265935<\/p>\n

Johnston-Cox HA, Koupenova M<\/b>, Ravid K. A2 adenosine receptors and vascular pathologies. Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):870-8. Review. PMID: 22423039<\/p>\n

Johnston-Cox H, Koupenova M<\/b>, Yang D, Corkey B, Gokce N, Farb MG, LeBrasseur N, Ravid K. The A2b adenosine receptor modulates glucose homeostasis and obesity. PLoS One. 2012;7(7):e40584. PMCID: PMC3405065<\/p>\n

Koupenova M<\/b>, Johnston-Cox H, Ravid K. Regulation of atherosclerosis and associated risk factors by adenosine and adenosine receptors. Curr Atheroscler Rep. 2012 Oct;14(5):460-8. Review. PMCID: PMC3759396<\/p>\n

Koupenova M<\/b>, Ravid K. Adenosine, adenosine receptors and their role in glucose homeostasis and lipid metabolism. J Cell Physiol. 2013 Mar 4. doi: 10.1002\/jcp.24352. [Epub ahead of print] PMID: 23460239<\/p>\n

Koupenova M<\/strong>, Vitseva O, Mackay CR, Beaulieu LM, Benjamin EJ, Mick E, Kurt-Jones EA, Ravid K, Freedman JE.\u00a0Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis.\u00a0Blood. 2014 Apr 22. [Epub ahead of print]\u00a0PMID: 24755410<\/p>\n

Wu X, Kong X, Luchsinger L,<\/b> Smith BD, Xu Y. Regulating the Activity of Class II Transactivator by Posttranslational Modifications: Exploring the Possibilities.\u00a0 Mol. Cell Biol.. 2009. 29(21), 5639-5644.\u00a0 PMCID: PMC2772741<\/p>\n

Xu Y, Luchsinger L,<\/b> Lucey E, Smith BD. The Effect of Class II Transactivator (CIITA) Mutations on Bleomycin Induced Inflammation and Lung Fibrosis.\u00a0 Am J Respir Cell Mol Biol.<\/i> 2010. Jun;44(6):898-905 PMCID: PMC3135849<\/p>\n

Luchsinger L<\/b>, Patenaude CA, Smith BD, Layne MD. Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts. J Biol Chem. 2011 Dec 23; 286(51): 44116-25 PMCID: PMC3243519<\/p>\n

Zee RS<\/b>, Yoo CB, Pimentel DR, Perlman DH, Burgoyne JR, Hou X, McComb ME, Costello CE, Cohen RA, Bachschmid MM. Redox regulation of sirtuin-1 by S-glutathiolation. Antioxid Redox Signal. 2010 Oct 1;13(7):1023-32. PMCID: PMC2959181<\/p>\n

Burgoyne JR, Haeussler DJ, Kumar V, Ji Y, Pimental DR, Zee RS<\/b>, Costello CE, Lin C, McComb ME, Cohen RA, Bachschmid MM. Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis. FASEB J. 2012 Feb;26(2):832-41. PMCID: PMC3290434<\/p>\n

Bachschmid MM, Schildknecht S, Matsui R, Zee R<\/b>, Haeussler D, Cohen RA, Pimental D, Loo Bv. Vascular aging: chronic oxidative stress and impairment of redox signaling-consequences for vascular homeostasis and disease. Ann Med. 2013 Feb;45(1):17-36. PMCID: PMC3717565<\/p>\n

Akinsheye I<\/b>, Klings E. Sickle Cell Anemia and Vascular Dysfunction:\u00a0 The Nitric Oxide Connection, Journal of Cellular Physiology. 2010. 224 (3) 620-5\u00a0 PMID: 20578237<\/p>\n

Akinsheye I<\/b>, Steinberg MH, David HK Chui. Molecular Characterization of the High Fetal Hemoglobin Phenotype in African American patients with Sickle Cell Anemia. Am J Hematol. 2011. PMICD:\u00a0 PMC3302931<\/p>\n

Akinsheye I<\/b>, Alsultan A, Solovieff N, Ngo D, Baldwin CT, Sebastiani P, Chui DH, Steinberg MH. Fetal Hemoglobin in Sickle Cell Anemia:\u00a0 Molecular Characterization of the High HbF Phenotype. Blood. 2011. PMCID: PMC3139383<\/p>\n

Ngo D, Akinsheye I<\/b>, Aygun B, Steinberg MH and David HK Chui.\u00a0 Fetal Hemoglobin and Hematologic Characterization of Compound Heterozygotes for HbS and Deletional Hereditary Persistence of Fetal Hemoglobin.\u00a0 Br J Haematol. 2012. 156 (2): 259-64 PMID: 22017641<\/p>\n

Ngo D, Steinberg MH, Akinsheye I<\/b>, David HK Chui, Alsultan A. Fetal hemoglobin in sickle cell anemia: Genetic studies of the Arab-Indian haplotype. Blood Cells Mol Dis. 2013. PMCID: PMC3647015<\/p>\n

Sazonova OV<\/b>, Lee KL, Isenberg BC, Rich CB, Nugent MA, Wong JY. Cell-cell interactions mediate the response of vascular smooth muscle cells to substrate stiffness. Biophysical Journal 2011. 101(3):622-30. PMCID: PMC3145282<\/p>\n

Pageau SC, Sazonova OV<\/b>, Wong JY, Soto AM, Sonnenschein C. The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture.\u00a0 Biomaterials. 2011.<\/i> 32(29):7169-80. PMID: 21724251<\/p>\n

Lin JB, Isenberg BC, Shen Y, Schorsch K, Sazonova OV<\/b>, Wong, JY. Poly(N -isopropylacrylamide) grafted from microtextured polydimethylsiloxane for aligned cell sheet engineering. Colloids and Surfaces B: Biointerface. 2012. <\/i>99:108-115. <\/i>PMID: <\/i>22088757<\/p>\n

Eliades A, Papadantonakis N, Bhupatiraju A, Burridge KA, Johnston-Cox HA<\/b>, Migliaccio AR, Crispino JD, Lucero HA, Trackman PC, Ravid K. Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase. J Biol Chem. 2011. 286(31):27630-8. PMCID: PMC3149354<\/p>\n

Johnston-Cox HA<\/b>, Ravid K. Adenosine and blood platelets. Purinergic Signal. 2011. 7(3):357-65. PMCID: PMC3166992<\/p>\n

Johnston-Cox HA<\/b>, Yang D, Ravid K. Physiological implications of adenosine receptor-mediated platelet aggregation. J Cell Physiol. 2011. 226(1):46-51. PMID: 20717958<\/p>\n

Koupenova M, Johnston-Cox H<\/b>, Ravid K. Regulation of atherosclerosis and associated risk factors by adenosine and adenosine receptors. Curr Atheroscler Rep. 2012.14(5):460-8. PMCID: PMC3759396<\/p>\n

Johnston-Cox H<\/b>, Koupenova M, Yang D, Corkey B, Gokce N, Farb MG, LeBrasseur N, Ravid K. The A2b adenosine receptor modulates glucose homeostasis and obesity. PLoS One. 2012. 7(7):e40584. PMCID: PMC3405065<\/p>\n

Johnston-Cox HA<\/b>, Koupenova M, Ravid K. A2 adenosine receptors and vascular pathologies. Arterioscler Thromb Vasc Biol. 2012. 32(4):870-8. PMID: 22423039<\/p>\n

Carroll SH, Wigner NA, Kulkarni N, Johnston-Cox H<\/b>, Gerstenfeld LC, Ravid K. A2B adenosine receptor promotes mesenchymal stem cell differentiation to osteoblasts and bone formation in vivo. J Biol Chem. 2012. 287(19):15718-27. PMCID: PMC3346096<\/p>\n

Koupenova M, Johnston-Cox H<\/b>, Vezeridis A, Gavras H, Yang D, Zannis V, Ravid K. 2012 Jan 17 A2b adenosine receptor regulates hyperlipidemia and atherosclerosis. Circulation.;125(2):354-63. PMCID: PMC3265935<\/p>\n

Johnston-Cox H<\/strong>, Eisenstein AS, Koupenova M, Carroll S, Ravid K.\u00a0The macrophage a2b adenosine receptor regulates tissue insulin sensitivity.\u00a0PLoS One. 2014 Jun 3;9(6):e98775.\u00a0PMID: 24892847<\/p>\n

Onguru D, Liang Y, Griffith Q<\/b>, Nikolajczyk B, Mwinzi P, Ganley-Leal L. Human schistosomiasis is associated with endotoxemia and Toll-like receptor 2- and 4-bearing B cells. Am J Trop Med Hyg. 2011 Feb; 84(2):321-4. PMCID: PMC3029191<\/p>\n

Griffith QK<\/b>, Liang Y, Onguru DO, Mwinzi PN, Ganley-Leal LM. CD23-bound IgE augments and dominates recall responses through human naive B cells. J Immunol. 2011 Jan 15;186(2):1060-7. PMID: 21160045<\/p>\n

Mitsche MA<\/b>, Wang L, Small DM. Adsorption of Egg-PC to an Air\/Water and Triolein\/Water Interface: Use of the 2-Dimensional Phase Rule to Estimate the Surface Composition of a Phospholipid\/Triolein\/Water Surface as a Function of Surface Pressure. Journal of Physical Chemistry 2010. B, 114(9) pp3276-3284. PMCID: PMC2851238<\/p>\n

Mitsche MA<\/b>, Small DM. C-terminus of Apolipoprotein A-I Removes Phospholipids (PL) from a Triolein\/PL\/Water Interface, but the N-Terminus does not: A possible mechanism for nascent HDL Assembly; Biophysical Journal. 2011. 101(2) pp. 353-361 (featured article)\u00a0 PMCID: PMC3136775<\/p>\n

Mitsche MA,<\/b> Small DS. Surface Pressure-dependent conformation change of apolipoprotein-derived amphipathic helices, J. Lipid Res. 2013. 54(6) 1578-1588.\u00a0 PMCID: PMC3646459<\/p>\n

Karki, S,<\/b> Chakrabarti P., Huang G., Wang H., Farmer SR, Kandror, KV. The multi-level action of fatty acids o adiponectine production by fat cells. PLosOne. 2011. PMCID: PMC3226650<\/p>\n

Farb MG, Tiwari S, Kark<\/b>i S, Ngo DT, Carmine B, Hess DT, Zuriaga MA, Walsh K, Fetterman JL, Hamburg NM, Vita JA, Apovian CM, Gokce N. Cyclooxygenase inhibition improves endothelial vasomotor dysfunction of visceral adipose arterioles in human obesity.\u00a0 Obesity. 2013. PMCID: PMC23640904<\/p>\n

Krasner NM<\/b>, Ido, Y, Ruderman NB, Cacicedo JM. Glucagon-like peptide-1 (GLP-1) analog liraglutide inhibits endothelial cell inflammation through a calcium and AMPK dependent mechanism.\u00a0PLoS One. 2014 May 16;9(5):e97554.\u00a0PMID: 24835252<\/p>\n

Ohashi K, Parker JL<\/b>, Ouchi N, Higuchi A, Vita JA, Gokce N, Pedersen AA, Kalthoff C, Tullin S, Sams A, Summer R, Walsh K. Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J Biol Chem. 2010 Feb 26;285(9):6153-60.\u00a0 Epub 2009 Dec 22. PMCID: PMC2825410<\/p>\n

Konter JM, Parker JL<\/b>, Baez E, Li SZ, Ranscht B, Denzel M, Little FF, Nakamura K, Ouchi N, Fine A, Walsh K, Summer RS. Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation. J Immunol. 2012. Jan 15;188(2):854-63. Epub 2011 Dec 7. PMCID: PMC3253176<\/p>\n

Ouchi N, Parker JL<\/b>, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol. 2011 Feb;11(2):85-97. Epub 2011 Jan 21. Review. PMCID: PMC3518031<\/p>\n

Parker-Duffen JL<\/b>, Nakamura K, Silver M, Kikuchi R, Tigges U, Yoshida S, Denzel M, Ranscht B and Walsh K. T-Cadherin is essential for adiponectin-mediated revascularization, J Biol Chem. 2013 Aug 23;288(34):24886-97.\u00a0 PMCID: PMC3750183<\/p>\n

Parker-Duffen JL <\/b>and Walsh K. Cardiometabolic effects of adiponectin, Best Pract Res Clin Endocrinol Metab.\u00a0Best Pract Res Clin Endocrinol Metab. 2014 Jan;28(1):81-91.\u00a0PMID: 24417948<\/p>\n

Parker-Duffen JL<\/b>, Nakamura K, Silver M, Zuriaga MA, Aprahamian TR, and Walsh K. Divergent roles for AdipoR1 and AdipoR2 in mediating revascularization and metabolic dysfunction in vivo. J Biol Chem. 2014 Apr 17,\u00a0[Epub ahead of print].\u00a0PMID: 24742672<\/p>\n

Calamaras TD<\/b>, Lee C, Lan F, Ido Y, Siwik DA, Colucci WS. Post-translational modification of serine\/threonine kinase LKB1 via Adduction of the Reactive Lipid Species 4-Hydroxy-trans-2-nonenal (HNE) at lysine residue 97 directly inhibits kinase activity. J Biol Chem. 2012 Dec 7;287(50):42400-6. Epub 2012 Oct 19. PMCID: PMC3516783<\/p>\n

Kumar V, Calamaras TD<\/b>, Haeussler D, Colucci WS, Cohen RA, McComb ME, Pimentel D, Bachschmid MM. Cardiovascular redox and ox stress proteomics. Antioxid Redox Signal. 2012 Dec 1;17(11):1528-59. Epub 2012 Aug 10. Review. PMCID: PMC3448941<\/p>\n

Qin F, Siwik DA, Luptak I, Hou X, Wang L, Higuchi A, Weisbrod RM, Ouchi N, Tu VH, Calamaras TD<\/b>, Miller EJ, Verbeuren TJ, Walsh K, Cohen RA, Colucci WS. The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation. 2012 Apr 10;125(14): 1757-64, S1-6.\u00a0 Epub 2012 Mar 2. PMCID: PMC335462<\/p>\n

Sun Y, Duan Y, Eisenstein AS<\/b>, Hu W, Quintana A, Lam WK, Wang Y, Wu Z, Ravid K, Huang P.\u00a0 A novel mechanism of control of NF\u03baB activation and inflammation involving A2B adenosine receptors. J Cell Sci. 2012 Oct 1;125(Pt 19):4507-17. Epub 2012 Jul 5. PMCID: PMC3500865<\/p>\n

Eisenstein A<\/b>, Ravid K. G protein-coupled receptors and adipogenesis: A focus on adenosine receptors. J Cell Physiol. 2013<\/p>\n

Isenberg BC, Backman DE<\/b>, Kinahan ME, Jesudason R, Suki B, Stone PJ, Davis EC, Wong JY. Micropatterned cell sheets with defined cell and extracellular matrix orientation exhibit anisotropic mechanical properties. J Biomech. 2012 Mar 15;45(5):756-61. Epub 2011 Dec 15. PMID: 22177672<\/p>\n

Mayer CL<\/b>, Leibowitz CS, Kurosawa S, Stearns-Kurosawa DJ. Shiga toxins and the pathophysilogy of hemolytic syndrome in humans and animals. Toxins (Basel). 2012. 4(11):1261:87. Review. PMCID: PMC3509707<\/p>\n

Lee BC, Mayer CL<\/b>, Leibowitz CS, Stearns-Kurosawa DJ, Kurosawa S. Quiescent complement in nonhuman primates during E coli Shiga toxin-induced hemolytic uremic syndrome and thrombotic microangiopathy. Blood. 2013. 122(5):803-6. PMCID: PMC3731933<\/p>\n

Wikstrom JD, Mahdaviani K<\/b>, Liesa M, Sereda SB, Si Y, Las G, Twig G, Petrovic N, Zingaretti C, Graham A, Cinti S, Corkey BE, Cannon B, Nedergaard J, Shirihai OS. Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure.\u00a0EMBO J. 2014 Mar 3;33(5):418-36.\u00a0PMID: 24431221, PMCID: PMC3983686<\/p>\n

Evangelista AM, Thompson MD<\/b>, Bolotina VM, Tong X, Cohen RA. Nox4- and Nox2-dependent oxidant production is required for VEGF-induced SERCA cysteine-674 S-glutathiolation and endothelial cell migration. Free Radic Biol Med. 2012. 53(12):2327-2334.\u00a0PMCID: PMC3568680<\/p>\n

Evangelista AM, Thompson MD<\/strong>, Weisbrod RM, Pimental DR, Tong X, Bolotina VM, Cohen RA.\u00a0Redox regulation of SERCA2 is required for vascular endothelial growth factor-induced signaling and endothelial cell migration.\u00a0Antioxid Redox Signal. 2012 Oct 15;17(8):1099-108. Epub 2012 May 31.
\nPMID: 22472004<\/p>\n

Mei Y, Thompson MD<\/strong>, Cohen RA, Tong X.\u00a0Endoplasmic Reticulum Stress and Related Pathological Processes.\u00a0J Pharmacol Biomed Anal. 2013 Nov 15;1(2):1000107.\u00a0PMID: 24611136<\/p>\n

Mei Y, Thompson MD<\/strong>, Cohen RA, Tong X.\u00a0Autophagy and oxidative stress in cardiovascular diseases.\u00a0Biochim Biophys Acta. 2014 May 13. pii: S0925-4439(14)00133-1. [Epub ahead of print] Review.\u00a0PMID: 24834848<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

NIHMS Submission and ID Number For Instructions click here:\u00a0NIHMSID number instructions Selected Representative Publications by Trainees in the past 10 years:\u00a0 Eisenstein A, Carroll SH, Johnston-Cox H, Farb M, Gokce N, Ravid K. An Adenosine Receptor-Kr\u00fcppel-like Factor 4 Protein Axis Inhibits Adipogenesis. J Biol Chem. 2014 Jul 25;289(30):21071-21081. PMCID:PMC4110311 Coughlan KA, Balon TW, Petrocelli R, […]<\/p>\n","protected":false},"author":1249,"featured_media":0,"parent":0,"menu_order":11,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/cardiograd\/wp-json\/wp\/v2\/pages\/207"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/cardiograd\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/cardiograd\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/cardiograd\/wp-json\/wp\/v2\/users\/1249"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/cardiograd\/wp-json\/wp\/v2\/comments?post=207"}],"version-history":[{"count":10,"href":"https:\/\/www.bumc.bu.edu\/cardiograd\/wp-json\/wp\/v2\/pages\/207\/revisions"}],"predecessor-version":[{"id":288,"href":"https:\/\/www.bumc.bu.edu\/cardiograd\/wp-json\/wp\/v2\/pages\/207\/revisions\/288"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/cardiograd\/wp-json\/wp\/v2\/media?parent=207"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}