{"id":6911,"date":"2013-12-04T14:02:52","date_gmt":"2013-12-04T19:02:52","guid":{"rendered":"http:\/\/www.bumc.bu.edu\/busm\/?p=4603"},"modified":"2013-12-04T14:02:52","modified_gmt":"2013-12-04T19:02:52","slug":"wolozin-receives-award-for-alzheimers-research","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/camed\/2013\/12\/04\/wolozin-receives-award-for-alzheimers-research\/","title":{"rendered":"Wolozin Receives Award for Alzheimer\u2019s Research"},"content":{"rendered":"<figure id=\"attachment_4606\" aria-describedby=\"caption-attachment-4606\" style=\"width: 210px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" src=\"\/camed\/files\/2013\/12\/wolozin-headshot-for-web.jpg\" alt=\"Wolozin\" title=\"wolozin headshot for web\" class=\"size-full wp-image-4606\" height=\"273\" width=\"200\" \/><figcaption id=\"caption-attachment-4606\" class=\"wp-caption-text\">Benjamin Wolozin<\/figcaption><\/figure>\n<p>Benjamin Wolozin, MD, PhD, associate professor of pharmacology and neurology at BUSM, has been awarded the Zenith Fellows Award from the Alzheimer\u2019s Association. The three-year, $450,000 award will support Wolozin\u2019s research in the pathogenesis of Alzheimer\u2019s disease. The goal of this work is to determine the molecular foundation of the proteins responsible for causing Alzheimer\u2019s.<\/p>\n<p>Wolozin will use molecular and cell culture approaches to investigate a novel molecular program causing formation neurofibrillary tangles. The tangles result from misfolding of tau proteins, which according to the researchers, leads to cognitive loss in individuals with Alzheimer\u2019s. The samples will be analyzed to characterize the signatures of the molecular program, termed stress granules, as they combine in the neurofibrillary tangle that forms in the brain.<\/p>\n<p>\u201cThis work could lead to a new understanding of disease mechanisms and novel therapeutics that are able to prevent pathological misfolding of tau protein,\u201d said Wolozin. \u201cThe Zenith Award emphasizes the importance of this work.\u201d<\/p>\n<p>Using a wide range of approaches from molecular to epidemiological to study neurodegenerative diseases, Wolizin\u2019s laboratory at BUSM focuses on the pathophysiology of Alzheimer\u2019s and Parkinson\u2019s disease, as well as amyotrophic lateral sclerosis. His previous research includes examining the role of cholesterol in Alzheimer\u2019s and how statins may affect the pathophysiology of the disease. His work on Parkinson\u2019s examines the interaction between genes and environmental factors implicated in the disease.<\/p>\n<p>Wolozin earned his MD and PhD from Albert Einstein College of Medicine. He completed postdoctoral fellowships and Mount Sinai Medical Center and the National Institute of Mental Health.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Benjamin Wolozin, MD, PhD, associate professor of pharmacology and neurology at BUSM, has been awarded the Zenith Fellows Award from the Alzheimer\u2019s Association. The three-year, $450,000 award will support Wolozin\u2019s research in the pathogenesis of Alzheimer\u2019s disease. The goal of this work is to determine the molecular foundation of the proteins responsible for causing Alzheimer\u2019s. [&hellip;]<\/p>\n","protected":false},"author":903,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/posts\/6911"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/users\/903"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/comments?post=6911"}],"version-history":[{"count":0,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/posts\/6911\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media?parent=6911"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/categories?post=6911"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/tags?post=6911"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}