{"id":117411,"date":"2023-11-02T14:08:48","date_gmt":"2023-11-02T18:08:48","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/camed\/?p=117411"},"modified":"2023-11-03T13:17:22","modified_gmt":"2023-11-03T17:17:22","slug":"framingham-heart-study-celebrates-75th-anniversary-of-historic-study","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/camed\/2023\/11\/02\/framingham-heart-study-celebrates-75th-anniversary-of-historic-study\/","title":{"rendered":"Framingham Heart Study Celebrates 75 Years of Research with Open House"},"content":{"rendered":"
\"Red
On Oct. 25, the Framingham Heart Study research center welcomed 300 participants and their guests to a 75th anniversary event in Framingham.<\/figcaption><\/figure>\n

In 1948, the first of 15,000 volunteer participants entered the research center of the historic Framingham Heart Study<\/a> (FHS) to have their vitals taken and other tests performed that would provide scientist with the facts they needed to fight heart disease and cardiovascular-related conditions like stroke and Alzheimer\u2019s disease.<\/p>\n

While the last person in the first cohort of over 5,000 volunteers who signed on in 1948 passed away at 105 earlier this year, participation was passed down generationally through families over time. On Wednesday, Oct. 25, nearly 300 participants and their guests visited the research center. They took tours covering eight distinct research areas with 20 principal investigators in research teams grouped together to cover a common theme, like neurology and cardiology.<\/p>\n

Over 40 research staff plus volunteers, including former FHS staff, were on hand to help and participants conversed with researchers whose work they\u2019d profoundly influenced, and with FHS staff who had known them for years or, in many cases, for decades.<\/p>\n

Appreciation went both ways.<\/p>\n

\"Woman
Longtime heart study participants Joanne Barber and John Villa.<\/figcaption><\/figure>\n

\u201cMy mother, my brother, my aunts, my first cousins,\u201d said Joanne Barber, 74, ticking off the generations of her family that have participated in the study from 1948 to today.<\/p>\n

\u201cI\u2019m just honored to be a part of it, with my father, my grandfather, my seven brothers,\u201d said John Villa, 69, who has lived in Framingham his whole life. \u201cI think it\u2019s great to help to find cures for all our ailments. The big ones. Nice to be a part of giving back to society.\u201d<\/p>\n

George O\u2019Connor<\/a>, MD, interim FHS co-director, said the generational record of participation for 75 years is unique in medical research. A professor of medicine at the Chobanian & Avedisian School of Medicine which oversees the study, O\u2019Connor has been a principal investigator at FHS for 31 years. He said the loyalty of participants over such a long period of time has created unforeseen research options.<\/p>\n

\u201cIt gives you a wealth of opportunities,\u201d he said. Along with the clinical data on health conditions, they also have longitudinal measures of pulmonary function, electrocardiograms, blood lipids, genetics and other data that helps deepen the understanding of what is going on in the human body over time and over generations.<\/p>\n

\u201cIt\u2019s just a remarkable achievement,\u201d said O\u2019Connor.<\/p>\n

\"Two
Most of their adult lives, Ruby Bishop and Anita Beckett have faithfully returned to Framingham to undergo a \u201csuper physical\u201d that supplies vital information to researchers<\/figcaption><\/figure>\n

Ruby Bishop and Anita Beckett were among the first Black participants as the study broadened its participant base from exclusively white European families to include Black, Hispanic, and Asian American families in the 1990s.<\/p>\n

\u201cI thought it would be a good thing,\u201d said Bishop. \u201cThere are little nuances brought on by our genetic makeup and our environment.\u201d<\/p>\n

\"Woman
Study participant Donna Boundy has been driving the three hour trip to FHS from her Woodstock, N.Y.home for most of her life.<\/figcaption><\/figure>\n

\u201cI really wanted to be in on the celebration,\u201d said Donna Boundy, 73, who drove over three hours from her home in Woodstock, New York, to attend, as she has done every three years for most of her life as a participant. Her mother and father were in the original cohort. She was looking forward to talking to researchers.<\/p>\n

\u201cI have no idea what study they\u2019re using (my information) for,\u201d Boundy said. \u201cI do it because it meant a lot to my father. It meant a lot to them; they were proud of it.\u201d<\/p>\n

\"Woman
Neurologist Sudha Seshadri, MD, a senior FHS investigator, explains her research to heart study participants.<\/figcaption><\/figure>\n

Researchers also traveled long distances to attend the celebration. Neurologist Sudha Seshadri<\/a>, MD, a senior FHS investigator and founding director of the University of Texas San Antonio Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases, came from San Antonio with her husband Vasan Ramachandran<\/a>, MD, the former longtime FHS director and now founding dean of the University of Texas School of Public Health at San Antonio. For most of the day, they explained to participants how their data was being used in research.<\/p>\n

\u201cI had to be here. It\u2019s now 30 years since I started working with the heart study,\u201d said Seshadri. \u201cThis is my life\u2019s work, just as it is for participants.\u201d<\/p>\n

See more on Facebook<\/a>.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Participants conversed with researchers whose work they\u2019d profoundly influenced, and with FHS staff who had known them for years or, in many cases, for decades.<\/p>\n","protected":false},"author":903,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[124,91,90],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/posts\/117411"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/users\/903"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/comments?post=117411"}],"version-history":[{"count":7,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/posts\/117411\/revisions"}],"predecessor-version":[{"id":117468,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/posts\/117411\/revisions\/117468"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media?parent=117411"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/categories?post=117411"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/tags?post=117411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}