{"id":1409,"date":"2015-05-19T13:57:26","date_gmt":"2015-05-19T17:57:26","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/camed\/?page_id=1409"},"modified":"2024-11-06T15:06:11","modified_gmt":"2024-11-06T20:06:11","slug":"ivis-imaging-core","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/camed\/research-impact\/cores\/ivis-imaging-core\/","title":{"rendered":"In Vivo Imaging Core Facility"},"content":{"rendered":"

Welcome to the\u00a0In Vivo Imaging Core Facility <\/strong> at Boston University Medical Campus. The In Vivo Imaging Core Facility <\/strong> is equipped with the following instruments:<\/p>\n

IVIS Spectrum (PerkinElmer)<\/h2>\n

The primary use of the IVIS Spectrum is to non-invasively and longitudinally monitor bio-luminescence and fluorescence in 2D and perform 3D optical tomography within small animal models (rats and mice); the instrument may also be used to assay optical signals in cells or comparatively sized tissue volumes post animal retrieval of specimens from larger animals. The instrument can monitor up to 5 mice at once, non-invasively and at high sensitivity, as well as multiple fluorescent and bio-luminescent reporters simultaneously.<\/p>\n

Quantum GX2 microCT Imaging System (PerkinElmer)<\/h2>\n

The Quantum GX2 provides low dose gated, high resolution X-ray scans for in vivo anatomical and functional imaging (with or without contrast agents, depending on specific applications). Examples of applications include assessment of lung fibrosis, lung edema, bone mineral density and structure, microvascular density (angiography), adipose tissue analysis and more. The Spectrum can be integrated with Quantum GX2 for exact co-registration of optical signals with anatomical landmarks, within each mouse, for increased quantitation accuracy.<\/p>\n

Living Image Acquisition\/Analysis Package<\/h2>\n

The system also includes a Living Image Acquisition\/Analysis Software Package, allowing for advanced quantification and analysis of all data acquired in 3 dimensions from each animal.<\/p>\n

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Internal Rates<\/span><\/h4>\n<\/td>\n

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Effective Rates: Internal*<\/span><\/h4>\n<\/td>\n

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External Rates<\/strong><\/span><\/h4>\n<\/td>\n<\/tr>\n

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Location<\/strong><\/span><\/h4>\n<\/td>\n

<\/span><\/em><\/td>\n(Principal Investigators within Boston University)<\/span><\/em><\/td>\nPIs within DOM<\/span><\/strong><\/td>\nDOM Subsidy<\/span><\/em><\/td>\nPIs outside of DOM<\/span><\/strong><\/td>\nDOM Subsidy<\/span><\/em><\/td>\n<\/td>\n<\/tr>\n
IVIS Spectrum #1 <\/a><\/td>\n700 Albany St., W913<\/td>\nUnassisted<\/em><\/td>\n$92 per hour<\/em><\/td>\n$55<\/strong><\/td>\n$37<\/em><\/td>\n$83<\/strong><\/td>\n$9<\/em><\/td>\n$164 per hour<\/strong><\/td>\n<\/tr>\n
<\/td>\n<\/td>\nAssisted<\/em><\/td>\n$125 per hour<\/em><\/td>\n$75<\/strong><\/td>\n$50<\/em><\/td>\n$113<\/strong><\/td>\n$12<\/em><\/td>\n$223 per hour<\/strong><\/td>\n<\/tr>\n
IVIS Spectrum # 2 <\/a><\/td>\n700 Albany St., W914<\/td>\nUnassisted<\/em><\/em><\/td>\n$92 per hour<\/em><\/td>\n$55<\/strong><\/td>\n$37<\/em><\/td>\n$83<\/strong><\/td>\n$9<\/em><\/td>\n$164 per hour<\/strong><\/td>\n<\/tr>\n
<\/td>\n<\/td>\nAssisted<\/em><\/td>\n$125 per hour<\/em><\/td>\n$75<\/strong><\/td>\n$50<\/em><\/td>\n$113<\/strong><\/td>\n$12<\/em><\/td>\n$223 per hour<\/strong><\/td>\n<\/tr>\n
Quantum GX2 microCT<\/a><\/td>\n700 Albany St., W914<\/td>\nUnassisted<\/em><\/em><\/td>\n$92 per hour<\/em><\/td>\n$55<\/strong><\/td>\n$37<\/em><\/td>\n$83<\/strong><\/td>\n$9<\/em><\/td>\n$164 per hour<\/strong><\/td>\n<\/tr>\n
<\/td>\n<\/td>\nAssisted<\/em><\/td>\n$125 per hour<\/em><\/td>\n$75<\/strong><\/td>\n$50<\/em><\/td>\n$113<\/strong><\/td>\n$12<\/em><\/td>\n$223 per hour<\/strong><\/td>\n<\/tr>\n
Living Image Acquisition\/Analysis Package<\/td>\n700 Albany St., W914<\/td>\n<\/em><\/td>\n$5 per 30 minutes unassisted<\/em><\/td>\n$5<\/strong><\/td>\n$2<\/em><\/td>\n$4.50<\/strong><\/td>\n$0.50<\/em><\/td>\n$12.50 per 30 minutes unassisted<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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*Department of Medicine (DOM) will subsidize 40% of internal rates for Principal Investigators with a primary appointment within the Department of Medicine, and 10% of internal rates for Principal investigators with a primary appointment at BU but outside the Department of Medicine.<\/p>\n

How to Schedule<\/strong><\/h3>\n

Please login to iLab Scheduling System<\/a> to schedule equipment time or services. For new users please follow the steps outlined in Information for New Users<\/a>.<\/p>\n

Hours of Operation: <\/strong>24\/7
\nTechnician Availability: <\/strong>By appointment only.<\/p>\n

Important information for External Investigators<\/strong><\/h3>\n

We strongly recommend external users to plan their studies at least 1-2 months in advance<\/strong><\/em>. Prior to using the In Vivo Imaging Core Facility, external investigators must:<\/p>\n