{"id":144537,"date":"2026-06-04T14:00:00","date_gmt":"2026-06-04T18:00:00","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/camed\/?post_type=bu-article&p=144537"},"modified":"2026-06-04T14:08:23","modified_gmt":"2026-06-04T18:08:23","slug":"new-research-aims-to-close-gaps-in-heart-failure-diagnosis","status":"publish","type":"bu-article","link":"https:\/\/www.bumc.bu.edu\/camed\/news-events\/articles\/2026\/new-research-aims-to-close-gaps-in-heart-failure-diagnosis\/","title":{"rendered":"New Research Aims to Close Gaps in Heart Failure Diagnosis"},"content":{"rendered":"\t
\n\t\t
\n\n\t\t\t
\n\t\t\t\t\n\t\t\t\t\"blue\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t

Photo by \u611a\u6728\u6df7\u682a Yumu<\/a> on Unsplash<\/a>.<\/p>\n\t\t\t\n\n\t\t\t\n\t\t\t\t

\n\n\t\t\t\t\t\n\t\t\t\t\t
\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\tHeart Disease<\/span>\n\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t New Research Aims to Close Gaps in Heart Failure Diagnosis \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/h1>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\n\t\t\t\t<\/div>\n\n\t\t\t\n\t\t<\/div>\n\n\t\t\n\t<\/div>\n\n\t\n
\n\t
\n\t\t\t\t\t
June 4, 2026<\/div>\n\t\t\n\t\t\t\t
\n\t\t\t\t\t<\/div>\n\t\t
\n\t\t\tTwitter<\/span><\/span>\n\t\t\tFacebook<\/span><\/span>\n\t\t\t<\/span>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\t\n\n\n

For many patients, symptoms like getting winded walking upstairs, feeling unusually tired, or experiencing swelling in their legs can be easy to dismiss as aging, stress, or weight gain. But for some, these symptoms are signs of heart failure with preserved ejection fraction, or HFpEF, a form of heart failure that now accounts for more than half of all heart failure cases in the United States<\/a>. It is also one of the most difficult forms of heart disease to diagnose.<\/p>\n\n\n\n

My hope is that this work helps us diagnose patients earlier, before they become severely ill or require hospitalization.<\/p>Lucy Schulson, MD, MPH<\/cite><\/blockquote>\n\n\n\n

\"Headshot
Lucy Schulson, MD, MPH<\/figcaption><\/figure><\/div>\n\n\n\n

That challenge, and the consequences when diagnosis comes too late, are at the center of new research led by Lucy Schulson<\/a>, MD, MPH, an assistant professor of medicine at Boston University Chobanian & Avedisian School of Medicine. \u201cA diagnosis can be life-changing for patients because it connects them to treatment, specialists, and a better understanding of what they\u2019re experiencing,\u201d says Schulson, who is also an internal medicine physician at Boston Medical Center. \u201cMy hope is that this work helps us diagnose patients earlier, before they become severely ill or require hospitalization.\u201d<\/p>\n\n\n\n

Schulson\u2019s work to improve how HFpEF is identified and diagnosed was recently selected for the National Academy of Medicine Scholars in Diagnostic Excellence program.<\/a><\/p><\/blockquote>\n\n\n\n

Schulson\u2019s work to improve how HFpEF is identified and diagnosed was recently selected for the National Academy of Medicine Scholars in Diagnostic Excellence program.<\/a> The program brings together national leaders who can drive implementation of effective strategies to reduce diagnostic errors in medicine, which include delayed diagnoses, misdiagnoses, and failures to communicate diagnoses to patients in a timely way.<\/p>\n\n\n\n

A Condition That Often Goes Unrecognized<\/h4>\n\n\n\n

For Schulson, HFpEF highlights a larger issue in medicine: some patients are more likely than others to experience delays in diagnosis. The condition is closely linked to hypertension, obesity, diabetes, and chronic lung disease, all of which are increasing in the United States<\/a>. Additionally, Black women experience the highest rates of HFpEF hospitalization<\/a>, and studies suggest Black patients are more likely to receive a heart failure diagnosis during an emergency department visit or hospitalization instead of in outpatient care<\/a>, where earlier intervention may have been possible.<\/p>\n\n\n\n

Schulson says that part of the problem is that HFpEF presents with symptoms that overlap with many other medical conditions, and diagnosing the condition often requires clinicians to piece together symptoms, imaging findings, medical history, and risk factors across multiple visits and systems.<\/p>\n\n\n\n

\u201cIn primary care, you\u2019re synthesizing huge amounts of information constantly,\u201d says Schulson. \u201cYou might have an echocardiogram report, specialist notes, emergency department records, and chronic disease management all happening at once. It\u2019s possible for a pattern to be overlooked.\u201d<\/p>\n\n\n\n

Using AI to Find Missed Heart Failure Diagnoses<\/h4>\n\n\n\n

That complexity is what led Schulson to explore whether artificial intelligence (AI) could help clinicians identify patients earlier. Using large language models, her team is studying whether AI tools can analyze clinical notes alongside echocardiogram reports and other data to flag patients who may have HFpEF but have not yet been diagnosed. The goal is not to replace clinicians, she says, but to help surface patterns that might otherwise be missed amid the volume of information providers manage every day.<\/p>\n\n\n\n

\u201cWe\u2019re doing more testing than ever before in medicine, and clinicians are managing an enormous amount of information,\u201d she said. \u201cThe question is whether these tools can help us better recognize patients who may otherwise fall through the cracks.\u201d<\/p>\n\n\n\n

The timing of that work is especially important because treatment options for HFpEF have changed significantly in recent years. For decades, there were few therapies specifically targeted to the condition. Newer medications can now help improve symptoms and reduce hospitalizations for some patients. \u201cA diagnosis matters because it connects patients to care,\u201d says Schulson. \u201cIt can mean access to cardiology specialists, medications, clinical trials, and support that may improve quality of life and long-term health outcomes.\u201d<\/p>\n\n\n\n

Looking Beyond Heart Failure<\/h4>\n\n\n\n

While HFpEF is the focus of the current research, Schulson sees broader implications. The same approach, she believes, could eventually help clinicians identify diagnostic delays in other chronic diseases where symptoms are nonspecific, care is fragmented, and disparities persist.<\/p>\n\n\n\n

\u201cThis is really about how we build systems that are better at recognizing disease early for everyone,\u201d she said. \u201cNot just for the populations medicine has historically been built around.\u201d<\/p>\n\n\n\n

Submitted by Gina Mantica<\/em>, Senior Research Communications Manager, BMC<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

For many patients, symptoms like getting winded walking upstairs, feeling unusually tired, or experiencing swelling in their legs can be easy to dismiss as aging, stress, or weight gain. But for some, these symptoms are signs of heart failure with preserved ejection fraction, or HFpEF, a form of heart failure that now accounts for more […]<\/p>\n","protected":false},"author":903,"featured_media":144542,"comment_status":"closed","ping_status":"closed","template":"","meta":{"bu_prepress_billboard":"","_bu_prepress_primary_term":"Heart Disease","_bu_prepress_primary_term_manual":""},"tags":[503,94],"bu-publication":[367],"medicine-article-category":[],"medicine-topic":[],"news-article-category":[385],"news-topic":[],"bu_edition":[390],"media_type":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article\/144537"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/types\/bu-article"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/users\/903"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/comments?post=144537"}],"version-history":[{"count":8,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article\/144537\/revisions"}],"predecessor-version":[{"id":144707,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article\/144537\/revisions\/144707"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media\/144542"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media?parent=144537"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/tags?post=144537"},{"taxonomy":"bu-publication","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-publication?post=144537"},{"taxonomy":"medicine-article-category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/medicine-article-category?post=144537"},{"taxonomy":"medicine-topic","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/medicine-topic?post=144537"},{"taxonomy":"news-article-category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/news-article-category?post=144537"},{"taxonomy":"news-topic","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/news-topic?post=144537"},{"taxonomy":"bu_edition","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu_edition?post=144537"},{"taxonomy":"media_type","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media_type?post=144537"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}