{"id":143549,"date":"2026-04-14T10:17:20","date_gmt":"2026-04-14T14:17:20","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/camed\/?post_type=bu-article&#038;p=143549"},"modified":"2026-04-14T10:18:12","modified_gmt":"2026-04-14T14:18:12","slug":"study-finds-how-people-approach-test-problems-not-just-how-many-answers-they-get-right-can-help-predict-future-dementia-risk","status":"publish","type":"bu-article","link":"https:\/\/www.bumc.bu.edu\/camed\/news-events\/articles\/2026\/study-finds-how-people-approach-test-problems-not-just-how-many-answers-they-get-right-can-help-predict-future-dementia-risk\/","title":{"rendered":"Study Finds How\u00a0People Approach Test Problems\u2014Not Just How Many Answers They Get Right\u2014Can Help Predict Future Dementia Risk"},"content":{"rendered":"\t<div class=\"wp-block-editorial-leadin news-block-editorial-leadin is-style-text-over-image has-media has-media-focus-center-middle has-text-position-x-center\">\n\t\t<div class=\"container-lockup\">\n\n\t\t\t<div class=\"wp-block-leadin-media\">\n\t\t\t\t\n\t\t\t\t<img width=\"2000\" height=\"1335\" src=\"\/camed\/files\/2022\/06\/BU-Today-Diagnosing-Dementia.jpg\" class=\"\" alt=\"Graphic of man standing being helped\/supported by woman\" loading=\"lazy\" srcset=\"https:\/\/www.bumc.bu.edu\/camed\/files\/2022\/06\/BU-Today-Diagnosing-Dementia.jpg 2000w, https:\/\/www.bumc.bu.edu\/camed\/files\/2022\/06\/BU-Today-Diagnosing-Dementia-636x425.jpg 636w, https:\/\/www.bumc.bu.edu\/camed\/files\/2022\/06\/BU-Today-Diagnosing-Dementia-1024x684.jpg 1024w, https:\/\/www.bumc.bu.edu\/camed\/files\/2022\/06\/BU-Today-Diagnosing-Dementia-768x513.jpg 768w, https:\/\/www.bumc.bu.edu\/camed\/files\/2022\/06\/BU-Today-Diagnosing-Dementia-1536x1025.jpg 1536w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"wp-block-editorial-leadin-caption wp-prepress-component-caption\">photo by iStock\/Ponomariova_Maria<\/p>\n\t\t\t\n\n\t\t\t\n\t\t\t\t<div class=\"container-words-outer\">\n\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"container-words-inner\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"wp-prepress-tag\">Research<\/span>\n\t\t\t\t\t\t\t\t<h1 class=\"head\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t <strong>Study Finds <em>How<\/em>\u00a0People Approach Test Problems\u2014Not Just How Many Answers They Get Right\u2014Can Help Predict Future Dementia Risk<\/strong> \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/h1>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"deck\"> <em>New research helps detect dementia risk earlier, when there is the greatest opportunity to intervene and preserve independence<\/em>. <\/h4>\n\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\n\t\t\t\t<\/div>\n\n\t\t\t\n\t\t<\/div>\n\n\t\t\n\t<\/div>\n\n\t\n<div class=\"wp-prepress-component-metabar news-prepress-layout-metabar\">\n\t<div class=\"wp-prepress-component-metabar-wrapper\">\n\t\t\t\t\t<div class=\"wp-prepress-component-metabar-date\">April 14, 2026<\/div>\n\t\t\n\t\t\t\t<div class=\"wp-prepress-component-metabar-credits\">\n\t\t\t\t\t<\/div>\n\t\t<div class=\"wp-prepress-component-metabar-share js-bu-prepress-share-tools\">\n\t\t\t<span class=\"icon-twitter\"><span>Twitter<\/span><\/span>\n\t\t\t<span class=\"icon-facebook\"><span>Facebook<\/span><\/span>\n\t\t\t<span class=\"icon-action\"><\/span>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\t\n\n\n<p class=\"has-drop-cap\">Scores from neuropsychological assessments (in-depth, standardized evaluations of how a person&#8217;s brain functions in various cognitive areas) are widely used to identify underlying cognitive abilities. However, a single score representing a specific cognitive domain often obscures the diverse strategies individuals may employ to complete the test. Additionally, reliance solely on scores can hide subtle cognitive changes, which are especially critical for early detection of cognitive disorders. <\/p>\n\n\n\n<div class=\"wp-block-image is-style-rounded\"><figure class=\"alignleft size-full is-resized\"><img loading=\"lazy\" src=\"\/camed\/files\/2023\/11\/Brandon-Frank-1.jpg\" alt=\"upper body shot of Brandon Frank wearing suit jacket and tie, smiling\" class=\"wp-image-136562\" width=\"144\" height=\"182\" srcset=\"https:\/\/www.bumc.bu.edu\/camed\/files\/2023\/11\/Brandon-Frank-1.jpg 476w, https:\/\/www.bumc.bu.edu\/camed\/files\/2023\/11\/Brandon-Frank-1-286x360.jpg 286w, https:\/\/www.bumc.bu.edu\/camed\/files\/2023\/11\/Brandon-Frank-1-406x512.jpg 406w\" sizes=\"(max-width: 144px) 100vw, 144px\" \/><figcaption>Brandon Frank, PhD<\/figcaption><\/figure><\/div>\n\n\n\n<p>A new study from researchers at Boston University Chobanian &amp; Avedisian School of Medicine and the VA Boston Healthcare System has found <em>how<\/em>&nbsp;people complete cognitive tests \u2014 including the small mistakes they make and the strategies they use \u2014 can predict who will later develop dementia, even years before diagnosis.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote\"><p>In our study, subtle cognitive features predicted dementia more than five years before diagnosis.<\/p><cite>Brandon Frank, PhD<\/cite><\/blockquote>\n\n\n\n<p>\u201cMany research studies focus on total test scores (for example, how many words someone remembers on a memory test). We showed that looking closely at patterns of errors and response styles provides deeper information. In our study, subtle cognitive features predicted dementia more than five years before diagnosis,\u201d explains corresponding author <a href=\"https:\/\/profiles.bu.edu\/Brandon.Frank\">Brandon Frank<\/a>, PhD, assistant professor of neurology at the school and clinical neuropsychologist at the VA.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" src=\"\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-1024x1024.jpg\" alt=\"Graphic showing steps to better identify how to detect dementia risk\" class=\"wp-image-143551\" width=\"400\" height=\"400\" srcset=\"https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large.jpg 1024w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-636x636.jpg 636w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-150x150.jpg 150w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-768x768.jpg 768w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-360x360.jpg 360w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-512x512.jpg 512w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-720x720.jpg 720w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-1000x1000.jpg 1000w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-500x500.jpg 500w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-300x300.jpg 300w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-600x600.jpg 600w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-550x550.jpg 550w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-710x710.jpg 710w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/04\/Dementia-Risk-Simplified-large-100x100.jpg 100w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><\/figure><\/div>\n\n\n\n<p>The researchers analyzed data from 2,363 adults over the age of 60 (none who had dementia prior to completing their testing) who were part of the Framingham Heart Study Brain Aging Program. The program, which has collected detailed cognitive data since 2005, not only records final test scores, but carefully and extensively documents <em>how<\/em>&nbsp;people perform on cognitive tests \u2014 including specific types of errors, problem-solving strategies, and subtle response patterns. The researchers then used advanced statistical modeling and machine learning to organize hundreds of small test details into meaningful brain-related patterns \u2014 and demonstrated that these patterns improve early detection of dementia risk.<\/p>\n\n\n\n<div class=\"wp-block-image is-style-rounded\"><figure class=\"alignleft size-full\"><img loading=\"lazy\" width=\"144\" height=\"180\" src=\"\/camed\/files\/2021\/02\/Ashita-Gurnani.jpg\" alt=\"image of Ashita Gurnani smiling broadly\" class=\"wp-image-92462\"\/><figcaption>Ashita Gurnani, PhD<\/figcaption><\/figure><\/div>\n\n\n\n<p>According to the researchers, subtle changes in thinking may be detectable earlier than is previously believed. \u201cClinically, this could improve early detection of dementia and help doctors identify who may benefit from closer monitoring, support earlier intervention when treatments are most effective, and reduce misdiagnosis caused by relying on single test scores,\u201d adds co-first author <a href=\"https:\/\/profiles.bu.edu\/Ashita.Gurnani\">Ashita Gurnani<\/a>, PhD, clinical neuropsychologist, assistant professor of neurology, and co-lead for the clinical core of the Framingham Heart Study Brain Aging Program.<\/p>\n\n\n\n<p>These <a href=\"https:\/\/www.cambridge.org\/core\/journals\/journal-of-the-international-neuropsychological-society\/article\/psychometric-modeling-of-boston-process-approach-data-for-dementia-prediction-in-the-framingham-heart-study\/10DFEDC644DAA8DDA75AC6630F42DD61\">findings appear online<\/a> in the Journal of the International Neuropsychological Society.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scores from neuropsychological assessments (in-depth, standardized evaluations of how a person&#8217;s brain functions in various cognitive areas) are widely used to identify underlying cognitive abilities. However, a single score representing a specific cognitive domain often obscures the diverse strategies individuals may employ to complete the test. Additionally, reliance solely on scores can hide subtle cognitive [&hellip;]<\/p>\n","protected":false},"author":903,"featured_media":143550,"comment_status":"closed","ping_status":"closed","template":"","meta":{"bu_prepress_billboard":"","_bu_prepress_primary_term":"","_bu_prepress_primary_term_manual":"Research"},"tags":[489,94],"bu-publication":[367],"medicine-article-category":[],"medicine-topic":[],"news-article-category":[385],"news-topic":[],"bu_edition":[390],"media_type":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article\/143549"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/types\/bu-article"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/users\/903"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/comments?post=143549"}],"version-history":[{"count":6,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article\/143549\/revisions"}],"predecessor-version":[{"id":143561,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article\/143549\/revisions\/143561"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media\/143550"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media?parent=143549"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/tags?post=143549"},{"taxonomy":"bu-publication","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-publication?post=143549"},{"taxonomy":"medicine-article-category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/medicine-article-category?post=143549"},{"taxonomy":"medicine-topic","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/medicine-topic?post=143549"},{"taxonomy":"news-article-category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/news-article-category?post=143549"},{"taxonomy":"news-topic","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/news-topic?post=143549"},{"taxonomy":"bu_edition","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu_edition?post=143549"},{"taxonomy":"media_type","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media_type?post=143549"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}