{"id":141053,"date":"2024-12-04T16:44:00","date_gmt":"2024-12-04T21:44:00","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/camed\/?post_type=bu-article&#038;p=141053"},"modified":"2026-01-19T11:42:23","modified_gmt":"2026-01-19T16:42:23","slug":"revisiting-vitamin-d-guidelines","status":"publish","type":"bu-article","link":"https:\/\/www.bumc.bu.edu\/camed\/news-events\/articles\/2024\/revisiting-vitamin-d-guidelines\/","title":{"rendered":"Revisiting Vitamin D Guidelines"},"content":{"rendered":"\t<div class=\"wp-block-editorial-leadin news-block-editorial-leadin is-style-side-by-side has-media has-flip has-media-focus-center-middle\">\n\t\t<div class=\"container-lockup\">\n\n\t\t\t<div class=\"wp-block-leadin-media\">\n\t\t\t\t\n\t\t\t\t<img width=\"1920\" height=\"2880\" src=\"\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash.jpg\" class=\"\" alt=\"Bottle of Vitamin D gummies next to sliced oranges.\" loading=\"lazy\" srcset=\"https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash.jpg 1920w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash-424x636.jpg 424w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash-683x1024.jpg 683w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash-768x1152.jpg 768w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash-1024x1536.jpg 1024w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash-1365x2048.jpg 1365w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash-240x360.jpg 240w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash-341x512.jpg 341w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash-480x720.jpg 480w, https:\/\/www.bumc.bu.edu\/camed\/files\/2026\/01\/maria-kozyr-nJ_Zr53cShA-unsplash-667x1000.jpg 667w\" sizes=\"(max-width: 1920px) 100vw, 1920px\" \/>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"wp-block-editorial-leadin-caption wp-prepress-component-caption\">Photo by <a href=\"https:\/\/unsplash.com\/@karami17?utm_source=unsplash&amp;utm_medium=referral&amp;utm_content=creditCopyText\">Maria Kozyr<\/a> on <a href=\"https:\/\/unsplash.com\/photos\/a-bottle-of-gummy-vitamins-sitting-on-top-of-a-wooden-table-nJ_Zr53cShA?utm_source=unsplash&amp;utm_medium=referral&amp;utm_content=creditCopyText\">Unsplash<\/a><\/p>\n\t\t\t\n\n\t\t\t\n\t\t\t\t<div class=\"container-words-outer\">\n\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"container-words-inner\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"wp-prepress-tag\">Research<\/span>\n\t\t\t\t\t\t\t\t<h1 class=\"head\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tRevisiting Vitamin D Guidelines\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/h1>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\n\t\t\t\t<\/div>\n\n\t\t\t\n\t\t<\/div>\n\n\t\t\n\t<\/div>\n\n\t\n<div class=\"wp-prepress-component-metabar js-block-editorial-metabar news-prepress-layout-metabar\">\n\t<div class=\"wp-prepress-component-metabar-wrapper\">\n\t\t\t\t\t<div class=\"wp-prepress-component-metabar-date\">December 4, 2024<\/div>\n\t\t\n\t\t\t\t<div class=\"wp-prepress-component-metabar-credits\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"wp-prepress-component-metabar-share js-bu-prepress-share-tools\">\n\t\t\t<span class=\"icon-twitter\"><span>Twitter<\/span><\/span>\n\t\t\t<span class=\"icon-facebook\"><span>Facebook<\/span><\/span>\n\t\t\t<span class=\"icon-action\"><\/span>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\t\n\n\n<p class=\"has-drop-cap\">In June of 2024, the Endocrine Society, influenced by a substantial body of research conducted in recent years, published new clinical practice guidelines for the testing and supplementation of Vitamin D for the prevention of disease. These new recommendations included limiting vitamin D supplementation beyond the daily recommended intake to specific risk groups and advised against routine 25-hydroxyvitamin D [25(OH)D] testing in healthy individuals.<\/p>\n\n\n\n<div class=\"wp-block-image size-full wp-image-82184\"><figure class=\"alignright\"><img loading=\"lazy\" width=\"180\" height=\"180\" src=\"\/camed\/files\/2015\/06\/Michael-Holick-1.jpg\" alt=\"head and shoulders of light skin, white hair man wearing white lab coat blue shirt, patterned necktie slightly smiling into camera\" class=\"wp-image-82184\" srcset=\"https:\/\/www.bumc.bu.edu\/camed\/files\/2015\/06\/Michael-Holick-1.jpg 180w, https:\/\/www.bumc.bu.edu\/camed\/files\/2015\/06\/Michael-Holick-1-150x150.jpg 150w, https:\/\/www.bumc.bu.edu\/camed\/files\/2015\/06\/Michael-Holick-1-100x100.jpg 100w\" sizes=\"(max-width: 180px) 100vw, 180px\" \/><figcaption>Michael Holick<\/figcaption><\/figure><\/div>\n\n\n\n<p>In a new <a href=\"https:\/\/www.endocrinepractice.org\/article\/S1530-891X(24)00804-8\/fulltext\">review article<\/a> in the journal, Endocrine Practice, <a href=\"https:\/\/profiles.bu.edu\/Michael.Holick\">Michael Holick<\/a>, PhD, MD, professor of medicine, pharmacology, physiology &amp; biophysics and molecular medicine at Boston University Chobanian &amp; Avedisian School of Medicine, compares and contrasts the 2024 Endocrine Society\u2019s Clinical Guidelines on Vitamin D with those he helped design in 2011.<\/p>\n\n\n\n<p>\u201cThe 2011 guidelines provided clinicians with guidance for how to evaluate and treat patients with vitamin D deficiency and prevent recurrence, whereas the 2024 guidelines made recommendations for the general healthy population for skeletal and extra skeletal health benefits of vitamin D. I believe this will cause great confusion for physicians and health care professionals as to how to determine if their patient who is at risk for vitamin D deficiency is vitamin D deficient since screening children and adults for their vitamin D status is not recommended in the new guidelines,\u201d explains Holick.<\/p>\n\n\n\n<p>Among the major differences:<\/p>\n\n\n\n<ul><li>The 2011 Guidelines provided physicians and health care professionals with guidance for when to evaluate a patient for their vitamin D status while the 2024 Guidelines do not.<\/li><li>The 2011 Guidelines provided health care professionals with information on how much vitamin D is required to treat and prevent vitamin D deficiency in all age groups. The 2024 Guidelines recommends vitamin D supplementation as proposed by the Institute of Medicine in 2010. However, the 2024 Guidelines only put forward the amount of vitamin D needed for anyone one year and older and provides no information for younger infants.<\/li><li>While the 2024 Guidelines acknowledge that increased vitamin D supplementation with a daily average intake of 2500 IUs may be of value in reducing risk of poor birth outcomes including preeclampsia, preterm births, small-for-gestational age births, neonatal mortality and cesarean section, it does not recommend monitoring vitamin D status in pregnant women and doesn\u2019t propose increased vitamin D intake above 600 IUs daily that is the dietary reference intakes for all adults.<\/li><\/ul>\n\n\n\n<p>According to Holick, the 2024 Guidelines ignored association studies and other studies and relied on randomized controlled trials, most of which were not placebo-controlled, for their recommendations. \u201cAs a result, they do not provide guidance for the many healthful benefits of vitamin D including: reducing cancer mortality by more than 25%; the incidence of metastatic and fatal cancer by 38%; autoimmune disorders by 39%, including type 1 diabetes by 88%; advancement of prediabetes to type 2 diabetes by 76%, peripheral vascular disease by 88% and lowering risk of respiratory tract infections by 58%. In terms of COVID 19 infection, hospitalizations and mortality was reduced by as much as 74%, 22% and 45% respectively, and accelerating COVID positive patients to COVID negativity by 66%; reducing risk of pre-term birth by 62% and preeclampsia and need for a cesarean section by more than 50%,\u201d he adds.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The 2024 guidelines don\u2019t give guidance on testing for Vitamin D insufficiency or on how much how much vitamin D is effective in improving a multitude of health issues.<\/p>\n","protected":false},"author":24243,"featured_media":141055,"comment_status":"closed","ping_status":"closed","template":"","meta":{"bu_prepress_billboard":"","_bu_prepress_primary_term":"Research","_bu_prepress_primary_term_manual":""},"tags":[94],"bu-publication":[367],"medicine-article-category":[],"medicine-topic":[],"news-article-category":[385],"news-topic":[],"bu_edition":[390],"media_type":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article\/141053"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/types\/bu-article"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/users\/24243"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/comments?post=141053"}],"version-history":[{"count":2,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article\/141053\/revisions"}],"predecessor-version":[{"id":141057,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-article\/141053\/revisions\/141057"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media\/141055"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media?parent=141053"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/tags?post=141053"},{"taxonomy":"bu-publication","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu-publication?post=141053"},{"taxonomy":"medicine-article-category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/medicine-article-category?post=141053"},{"taxonomy":"medicine-topic","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/medicine-topic?post=141053"},{"taxonomy":"news-article-category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/news-article-category?post=141053"},{"taxonomy":"news-topic","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/news-topic?post=141053"},{"taxonomy":"bu_edition","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/bu_edition?post=141053"},{"taxonomy":"media_type","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/camed\/wp-json\/wp\/v2\/media_type?post=141053"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}