Osamu Sakai, MD, PhD

Professor, Radiology

Osamu Sakai
820 Harrison Ave


Dr. Sakai was born and raised in Japan. He graduated from Yamagata University School of Medicine, Japan in 1988, and completed radiology residency at Jichi Medical School Hospital, Japan in 1993, and served as a faculty at Jichi Medical School in 1993-2001. He received his PhD from Jichi Medical School in 1998. Dr. Sakai first came to Boston as a research fellow at Massachusetts Eye and Ear Infirmary, Harvard Medical School in 1998-1999. After the fellowship he went back home but two years later he joined Boston Medical Center as a neuroradiology fellow in 2001. After his completion of neuroradiology fellowship, he stayed at BU/BMC as a faculty in Radiology.

Dr. Sakai is a board-certified radiologist in both Japan and the U.S. with neuroradiology subspecialty board certification. He was trained and has been practicing, teaching and conducting research in different languages and cultures, which helps him understand students, residents/fellows, colleagues as well as patients from different backgrounds. Dr. Sakai’s academic interest is neuroradiology and head and neck radiology. He has published multiple books and chapters in the U.S. and Japan in both English and Japanese. His research interests are diverse and include head and neck cancer, sickle cell disease, amyloidosis, aging, and trauma.

Other Positions

  • Section Chief of Neuroradiology, Neuroradiology, Radiology, Boston University Chobanian & Avedisian School of Medicine
  • Professor, Otolaryngology-Head & Neck Surgery, Boston University Chobanian & Avedisian School of Medicine
  • Professor, Radiation Oncology, Boston University Chobanian & Avedisian School of Medicine
  • Member, BU-BMC Cancer Center, Boston University


  • Yamagata University, MD
  • Jichi Medical University, PhD


  • Published on 9/22/2023

    Fazelpour S, Vejdani-Jahromi M, Kaliaev A, Qiu E, Goodman D, Andreu-Arasa VC, Fujima N, Sakai O. Multiparametric machine learning algorithm for human papillomavirus status and survival prediction in oropharyngeal cancer patients. Head Neck. 2023 Sep 22. PMID: 37740534.

    Read at: PubMed
  • Published on 8/3/2023

    Kawashima Y, Fujita A, Buch K, Qureshi MM, Li B, Takumi K, Rai A, Chapman MN, Sakai O. Using Texture Analysis of Neck Computed Tomography Images to Differentiate Primary Hyperparathyroidism From Normal Controls. J Comput Assist Tomogr. 2023 Aug 03. PMID: 37531643.

    Read at: PubMed
  • Published on 8/30/2022

    Jara H, Sakai O, Farrher E, Oros-Peusquens AM, Shah NJ, Alsop DC, Keenan KE. Primary Multiparametric Quantitative Brain MRI: State-of-the-Art Relaxometric and Proton Density Mapping Techniques. Radiology. 2022 Oct; 305(1):5-18. PMID: 36040334.

    Read at: PubMed
  • Published on 4/26/2022

    McNaughton R, Pieper C, Sakai O, Rollins JV, Zhang X, Kennedy DN, Frazier JA, Douglass L, Heeren T, Fry RC, O'Shea TM, Kuban KK, Jara H. Quantitative MRI Characterization of the Extremely Preterm Brain at Adolescence: Atypical versus Neurotypical Developmental Pathways. Radiology. 2022 Aug; 304(2):419-428. PMID: 35471112.

    Read at: PubMed
  • Published on 2/15/2022

    Siravegna G, O'Boyle CJ, Varmeh S, Queenan N, Michel A, Stein J, Thierauf J, Sadow PM, Faquin WC, Perry SK, Bard AZ, Wang W, Deschler DG, Emerick KS, Varvares MA, Park JC, Clark JR, Chan AW, Andreu Arasa VC, Sakai O, Lennerz J, Corcoran RB, Wirth LJ, Lin DT, Iafrate AJ, Richmon JD, Faden DL. Cell-Free HPV DNA Provides an Accurate and Rapid Diagnosis of HPV-Associated Head and Neck Cancer. Clin Cancer Res. 2022 02 15; 28(4):719-727. PMID: 34857594.

    Read at: PubMed
  • Published on 2/11/2022

    Ito K, Hirahara N, Muraoka H, Okada S, Kondo T, Andreu-Arasa VC, Sakai O, Kaneda T. Normal Variants of the Oral and Maxillofacial Region: Mimics and Pitfalls. Radiographics. 2022 Mar-Apr; 42(2):506-521. PMID: 35148245.

    Read at: PubMed
  • Published on 8/6/2021

    Fujima N, Andreu-Arasa VC, Meibom SK, Mercier GA, Truong MT, Hirata K, Yasuda K, Kano S, Homma A, Kudo K, Sakai O. Prediction of the local treatment outcome in patients with oropharyngeal squamous cell carcinoma using deep learning analysis of pretreatment FDG-PET images. BMC Cancer. 2021 Aug 06; 21(1):900. PMID: 34362317.

    Read at: PubMed
  • Published on 7/29/2021

    Ito K, Kondo T, Andreu-Arasa VC, Li B, Hirahara N, Muraoka H, Sakai O, Kaneda T. Quantitative assessment of the maxillary sinusitis using computed tomography texture analysis: odontogenic vs non-odontogenic etiology. Oral Radiol. 2022 Jul; 38(3):315-324. PMID: 34327595.

    Read at: PubMed
  • Published on 5/25/2021

    Abdalkader M, Nguyen TN, Norbash AM, Raz E, Shapiro M, Lenck S, Brinjikji W, Weber P, Sakai O. State of the Art: Venous Causes of Pulsatile Tinnitus and Diagnostic Considerations Guiding Endovascular Therapy. Radiology. 2021 07; 300(1):2-16. PMID: 34032509.

    Read at: PubMed
  • Published on 5/4/2021

    Safavi AR, Brook CD, Sakai O, Setty BN, Zumwalt A, Gonzalez M, Platt MP. Urgency of Esophageal Foreign Body Removal: Differentiation Between Coins and Button Cell Batteries. Otolaryngol Head Neck Surg. 2022 01; 166(1):80-85. PMID: 33940963.

    Read at: PubMed

View 157 more publications: View full profile at BUMC

View all profiles