Xueping Fan, MD, PhD
Assistant Professor, Medicine
Biography
Expertise includes: Protein biochemistry; Signaling pathway study; Cell biology; Molecular genetics; Molecular nephrology; Neuroscience; and Pharmacology.
Other Positions
- Boston Medical Center
Websites
Education
- Zhejiang University, MD
- McGill University, PhD
- McGill University, MSc
Publications
- Published on 3/24/2020
Pisarek-Horowitz A, Fan X, Kumar S, Rasouly HM, Sharma R, Chen H, Coser K, Bluette CT, Hirenallur-Shanthappa D, Anderson SR, Yang H, Beck LH, Bonegio RG, Henderson JM, Berasi SP, Salant DJ, Lu W. Loss of Roundabout Guidance Receptor 2 (Robo2) in Podocytes Protects Adult Mice from Glomerular Injury by Maintaining Podocyte Foot Process Structure. Am J Pathol. 2020 04; 190(4):799-816. PMID: 32220420.
Read at: PubMed - Published on 11/17/2016
Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W. SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. JCI Insight. 2016 11 17; 1(19):e86934. PMID: 27882344.
Read at: PubMed - Published on 7/12/2012
Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W. Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26; 2(1):52-61. PMID: 22840396.
Read at: PubMed - Published on 2/14/2007
Lu W, van Eerde AM, Fan X, Quintero-Rivera F, Kulkarni S, Ferguson H, Kim HG, Fan Y, Xi Q, Li QG, Sanlaville D, Andrews W, Sundaresan V, Bi W, Yan J, Giltay JC, Wijmenga C, de Jong TP, Feather SA, Woolf AS, Rao Y, Lupski JR, Eccles MR, Quade BJ, Gusella JF, Morton CC, Maas RL. Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux. Am J Hum Genet. 2007 Apr; 80(4):616-32. PMID: 17357069.
Read at: PubMed - Published on 9/1/2005
Abu-Baker A, Laganiere S, Fan X, Laganiere J, Brais B, Rouleau GA. Cytoplasmic targeting of mutant poly(A)-binding protein nuclear 1 suppresses protein aggregation and toxicity in oculopharyngeal muscular dystrophy. Traffic. 2005 Sep; 6(9):766-79. PMID: 16101680.
Read at: PubMed - Published on 9/25/2003
Fan X, Labrador JP, Hing H, Bashaw GJ. Slit stimulation recruits Dock and Pak to the roundabout receptor and increases Rac activity to regulate axon repulsion at the CNS midline. Neuron. 2003 Sep 25; 40(1):113-27. PMID: 14527437.
Read at: PubMed - Published on 8/1/2003
Fan X, Messaed C, Dion P, Laganiere J, Brais B, Karpati G, Rouleau GA. HnRNP A1 and A/B interaction with PABPN1 in oculopharyngeal muscular dystrophy. Can J Neurol Sci. 2003 Aug; 30(3):244-51. PMID: 12945950.
Read at: PubMed - Published on 2/1/2003
Fan X, Rouleau GA. Progress in understanding the pathogenesis of oculopharyngeal muscular dystrophy. Can J Neurol Sci. 2003 Feb; 30(1):8-14. PMID: 12619777.
Read at: PubMed - Published on 10/1/2001
Fan X, Dion P, Laganiere J, Brais B, Rouleau GA. Oligomerization of polyalanine expanded PABPN1 facilitates nuclear protein aggregation that is associated with cell death. Hum Mol Genet. 2001 Oct 1; 10(21):2341-51. PMID: 11689481.
Read at: PubMed - Published on 6/29/2001
Jannatipour M, Dion P, Khan S, Jindal H, Fan X, Laganière J, Chishti AH, Rouleau GA. Schwannomin isoform-1 interacts with syntenin via PDZ domains. J Biol Chem. 2001 Aug 31; 276(35):33093-100. PMID: 11432873.
Read at: PubMed
View 2 more publications: View full profile at BUMC