Ting Zhao, MD
Associate Professor, Surgery
Biography
Ting earned his PhD in Cell Biology from Peking University, China in 2016 under the supervision of Professor Hongkui Deng. In his PhD study, he and colleagues originally developed and optimized a robust chemically-induced reprogramming system, which is a novel approach to convert mature cells into a pluripotent state by the induction of small molecules (Zhao et al., Cell, 2015, co-first author). Then, he and colleagues investigated the molecular roadmap of chemical reprogramming by single-cell RNA-sequencing and uncovered new mechanistic insights into the nature of induced pluripotency (Zhao et al., Cell Stem Cell, 2018).
Other Positions
- Roger Williams Medical Center
Education
- Peking University, MD
Publications
- Published on 8/13/2021
Yano N, Zhao YT, Zhao TC. The Physiological Role of Irisin in the Regulation of Muscle Glucose Homeostasis. Endocrines. 2021 Sep; 2(3):266-283. PMID: 35392577.
Read at: PubMed - Published on 7/27/2021
Du J, Zhao YT, Wang H, Zhang LX, Qin G, Zhuang S, Kadin M, Chin YE, Liu PY, Zhao TC. The Essential Role of PRAK in Preserving Cardiac Function and Insulin Resistance in High-Fat Diet-Induced Diabetes. Int J Mol Sci. 2021 Jul 27; 22(15). PMID: 34360761.
Read at: PubMed - Published on 7/29/2020
Wang Z, Zhao YT, Zhao TC. Histone deacetylases in modulating cardiac disease and their clinical translational and therapeutic implications. Exp Biol Med (Maywood). 2021 01; 246(2):213-225. PMID: 32727215.
Read at: PubMed - Published on 6/3/2020
Wang J, Zhao YT, Zhang L, Dubielecka PM, Zhuang S, Qin G, Chin YE, Zhang S, Zhao TC. Irisin Improves Myocardial Performance and Attenuates Insulin Resistance in Spontaneous Mutation (Leprdb ) Mice. Front Pharmacol. 2020; 11:769. PMID: 32581784.
Read at: PubMed - Published on 5/22/2020
Zhao TC, Wang Z, Zhao TY. The important role of histone deacetylases in modulating vascular physiology and arteriosclerosis. Atherosclerosis. 2020 06; 303:36-42. PMID: 32535412.
Read at: PubMed - Published on 4/12/2020
Zhang Y, Zou J, Tolbert E, Zhao TC, Bayliss G, Zhuang S. Identification of histone deacetylase 8 as a novel therapeutic target for renal fibrosis. FASEB J. 2020 06; 34(6):7295-7310. PMID: 32281211.
Read at: PubMed - Published on 3/17/2020
Yano N, Zhang L, Wei D, Dubielecka PM, Wei L, Zhuang S, Zhu P, Qin G, Liu PY, Chin YE, Zhao TC. Irisin counteracts high glucose and fatty acid-induced cytotoxicity by preserving the AMPK-insulin receptor signaling axis in C2C12 myoblasts. Am J Physiol Endocrinol Metab. 2020 05 01; 318(5):E791-E805. PMID: 32182124.
Read at: PubMed - Published on 10/19/2019
Han S, Xu S, Zhou J, Qiao A, Boriboun C, Ma W, Li H, Biyashev D, Yang L, Zhang E, Liu Q, Jiang S, Zhao TC, Krishnamurthy P, Zhang C, Richard S, Qiu H, Zhang J, Qin G. Sam68 impedes the recovery of arterial injury by augmenting inflammatory response. J Mol Cell Cardiol. 2019 12; 137:82-92. PMID: 31639388.
Read at: PubMed - Published on 8/2/2019
Liu L, Zou J, Guan Y, Zhang Y, Zhang W, Zhou X, Xiong C, Tolbert E, Zhao TC, Bayliss G, Zhuang S. Blocking the histone lysine 79 methyltransferase DOT1L alleviates renal fibrosis through inhibition of renal fibroblast activation and epithelial-mesenchymal transition. FASEB J. 2019 11; 33(11):11941-11958. PMID: 31373855.
Read at: PubMed - Published on 7/10/2019
Zhao YT, Du J, Yano N, Wang H, Wang J, Dubielecka PM, Zhang LX, Qin G, Zhuang S, Liu PY, Chin YE, Zhao TC. p38-Regulated/activated protein kinase plays a pivotal role in protecting heart against ischemia-reperfusion injury and preserving cardiac performance. Am J Physiol Cell Physiol. 2019 09 01; 317(3):C525-C533. PMID: 31291142.
Read at: PubMed
View 62 more publications: View full profile at BUMC