My expertise is in understanding the pathogenesis of diabetic microvascular complications. In particular, studying the effect of high glucose in retinal endothelial cells, pericytes, and Muller cell gene expression.
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
- Professor, Ophthalmology, Boston University School of Medicine
- Boston Medical Center
- Boston University, PhD
- University of Kalyani, MS
- University of Kalyani, BS
- Published on 5/8/2018
Kim D, Mouritzen U, Larsen BD, Roy S. Inhibition of Cx43 gap junction uncoupling prevents high glucose-induced apoptosis and reduces excess cell monolayer permeability in retinal vascular endothelial cells. Exp Eye Res. 2018 May 08. PMID: 29750972.
- Published on 6/28/2017
Roy S, Kim D, Lim R. Cell-cell communication in diabetic retinopathy. Vision Res. 2017 10; 139:115-122. PMID: 28583293.
- Published on 6/8/2017
Roy S, Jiang JX, Li AF, Kim D. Connexin channel and its role in diabetic retinopathy. Prog Retin Eye Res. 2017 Nov; 61:35-59. PMID: 28602949.
- Published on 6/1/2017
Tien T, Zhang J, Muto T, Kim D, Sarthy VP, Roy S. High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2017 Jun 01; 58(7):2915-2921. PMID: 28586916.
- Published on 5/1/2017
Kim D, Mecham RP, Trackman PC, Roy S. Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced Apoptosis. Invest Ophthalmol Vis Sci. 2017 May 01; 58(5):2725-2731. PMID: 28538980.
- Published on 11/12/2016
Roy S, Kern TS, Song B, Stuebe C. Mechanistic Insights into Pathological Changes in the Diabetic Retina: Implications for Targeting Diabetic Retinopathy. Am J Pathol. 2017 Jan; 187(1):9-19. PMID: 27846381.
- Published on 3/22/2016
Hymowitz MB, Chang D, Feinberg EB, Roy S. Increased Intraocular Pressure and Hyperglycemic Level in Diabetic Patients. PLoS One. 2016; 11(3):e0151833. PMID: 27002725.
- Published on 1/1/2016
Roy S, Amin S, Roy S. Retinal fibrosis in diabetic retinopathy. Exp Eye Res. 2016 Jan; 142:71-5. PMID: 26675403.
- Published on 12/29/2015
Tien T, Muto T, Zhang J, Sohn EH, Mullins RF, Roy S. Association of reduced Connexin 43 expression with retinal vascular lesions in human diabetic retinopathy. Exp Eye Res. 2016 May; 146:103-6. PMID: 26738943.
- Published on 8/18/2015
Roy S, Kim D, Hernández C, Simó R, Roy S. Beneficial effects of fenofibric acid on overexpression of extracellular matrix components, COX-2, and impairment of endothelial permeability associated with diabetic retinopathy. Exp Eye Res. 2015 Nov; 140:124-9. PMID: 26297615.
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