Sayon Roy, PhD, FARVO

Professor, Ophthalmology

Sayon Roy
650 Albany St Evans Biomed Research Ctr


My expertise is in understanding the pathogenesis of diabetic microvascular complications. In particular, studying the effect of high glucose in retinal endothelial cells, pericytes, and Muller cell gene expression.

Other Positions

  • Professor, Endocrinology, Diabetes, Nutrition & Weight Management, Medicine, Boston University School of Medicine
  • Boston Medical Center
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences


  • Boston University, PhD
  • University of Kalyani, MS
  • University of Kalyani, BS


  • Published on 7/10/2020

    Kim D, Sankaramoorthy A, Roy S. Downregulation of Drp1 and Fis1 Inhibits Mitochondrial Fission and Prevents High Glucose-Induced Apoptosis in Retinal Endothelial Cells. Cells. 2020 Jul 10; 9(7). PMID: 32664237.

    Read at: PubMed
  • Published on 4/9/2020

    Nguyen NH, Kim D, Roy S. High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2020 Apr 09; 61(4):40. PMID: 32340032.

    Read at: PubMed
  • Published on 9/21/2019

    Subramanian ML, Stein TD, Siegel N, Ness S, Fiorello MG, Kim D, Roy S. Upregulation of Lysyl Oxidase Expression in Vitreous of Diabetic Subjects: Implications for Diabetic Retinopathy. Cells. 2019 09 21; 8(10). PMID: 31546618.

    Read at: PubMed
  • Published on 9/16/2019

    Kim D, Lee D, Trackman PC, Roy S. Effects of High Glucose-Induced Lysyl Oxidase Propeptide on Retinal Endothelial Cell Survival: Implications for Diabetic Retinopathy. Am J Pathol. 2019 10; 189(10):1945-1952. PMID: 31537300.

    Read at: PubMed
  • Published on 9/1/2019

    Roy S, Kim D, Sankaramoorthy A. Mitochondrial Structural Changes in the Pathogenesis of Diabetic Retinopathy. J Clin Med. 2019 Sep 01; 8(9). PMID: 31480638.

    Read at: PubMed
  • Published on 8/7/2019

    Daley EJ, Pajevic PD, Roy S, Trackman PC. Impaired Gastric Hormone Regulation of Osteoblasts and Lysyl Oxidase Drives Bone Disease in Diabetes Mellitus. JBMR Plus. 2019 Oct; 3(10):e10212. PMID: 31687648.

    Read at: PubMed
  • Published on 5/6/2019

    Kim D, Mecham RP, Nguyen NH, Roy S. Decreased lysyl oxidase level protects against development of retinal vascular lesions in diabetic retinopathy. Exp Eye Res. 2019 07; 184:221-226. PMID: 31022398.

    Read at: PubMed
  • Published on 12/3/2018

    Song B, Kim D, Nguyen NH, Roy S. Inhibition of Diabetes-Induced Lysyl Oxidase Overexpression Prevents Retinal Vascular Lesions Associated With Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2018 12 03; 59(15):5965-5972. PMID: 30550614.

    Read at: PubMed
  • Published on 8/2/2018

    Consigli A, Papanastasiou A, Roquelaure D, Wuarin R, Roy S, Thumann G, Chronopoulos A. [Changes in Retinal Vascular Caliber after Intravitreal Aflibercept Treatment for Diabetic Macular Oedema]. Klin Monbl Augenheilkd. 2019 Nov; 236(11):1318-1324. PMID: 30071565.

    Read at: PubMed
  • Published on 5/9/2018

    Kim D, Mouritzen U, Larsen BD, Roy S. Inhibition of Cx43 gap junction uncoupling prevents high glucose-induced apoptosis and reduces excess cell monolayer permeability in retinal vascular endothelial cells. Exp Eye Res. 2018 08; 173:85-90. PMID: 29750972.

    Read at: PubMed

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