My expertise is in understanding the pathogenesis of diabetic microvascular complications. In particular, studying the effect of high glucose in retinal endothelial cells, pericytes, and Muller cell gene expression.
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
- Professor, Ophthalmology, Boston University School of Medicine
- Boston Medical Center
- Boston University, PhD
- University of Kalyani, MS
- University of Kalyani, BS
- Published on 12/3/2018
Song B, Kim D, Nguyen NH, Roy S. Inhibition of Diabetes-Induced Lysyl Oxidase Overexpression Prevents Retinal Vascular Lesions Associated With Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2018 Dec 03; 59(15):5965-5972. PMID: 30550614.
- Published on 8/2/2018
Consigli A, Papanastasiou A, Roquelaure D, Wuarin R, Roy S, Thumann G, Chronopoulos A. [Changes in Retinal Vascular Caliber after Intravitreal Aflibercept Treatment for Diabetic Macular Oedema]. Klin Monbl Augenheilkd. 2018 Aug 02. PMID: 30071565.
- Published on 5/9/2018
Kim D, Mouritzen U, Larsen BD, Roy S. Inhibition of Cx43 gap junction uncoupling prevents high glucose-induced apoptosis and reduces excess cell monolayer permeability in retinal vascular endothelial cells. Exp Eye Res. 2018 08; 173:85-90. PMID: 29750972.
- Published on 12/4/2017
Zhang L, Song W, Shao D, Zhang S, Desai M, Ness S, Roy S, Yi J. Volumetric fluorescence retinal imaging in vivo over a 30-degree field of view by oblique scanning laser ophthalmoscopy (oSLO). Biomed Opt Express. 2018 01 01; 9(1):25-40. PMID: 29359085.
- Published on 6/28/2017
Roy S, Kim D, Lim R. Cell-cell communication in diabetic retinopathy. Vision Res. 2017 10; 139:115-122. PMID: 28583293.
- Published on 6/8/2017
Roy S, Jiang JX, Li AF, Kim D. Connexin channel and its role in diabetic retinopathy. Prog Retin Eye Res. 2017 Nov; 61:35-59. PMID: 28602949.
- Published on 6/1/2017
Tien T, Zhang J, Muto T, Kim D, Sarthy VP, Roy S. High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2017 Jun 01; 58(7):2915-2921. PMID: 28586916.
- Published on 5/1/2017
Kim D, Mecham RP, Trackman PC, Roy S. Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced Apoptosis. Invest Ophthalmol Vis Sci. 2017 May 01; 58(5):2725-2731. PMID: 28538980.
- Published on 11/12/2016
Roy S, Kern TS, Song B, Stuebe C. Mechanistic Insights into Pathological Changes in the Diabetic Retina: Implications for Targeting Diabetic Retinopathy. Am J Pathol. 2017 Jan; 187(1):9-19. PMID: 27846381.
- Published on 3/22/2016
Hymowitz MB, Chang D, Feinberg EB, Roy S. Increased Intraocular Pressure and Hyperglycemic Level in Diabetic Patients. PLoS One. 2016; 11(3):e0151833. PMID: 27002725.
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