Sayon Roy, PhD, FARVO

Professor, Medicine

Sayon Roy
617.638.4110
650 Albany St Evans Biomed Research Ctr

Biography

My expertise is in understanding the pathogenesis of diabetic microvascular complications. In particular, studying the effect of high glucose in retinal endothelial cells, pericytes, and Muller cell gene expression.

Other Positions

  • Professor, Ophthalmology, Boston University School of Medicine
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
  • Boston Medical Center

Education

  • Boston University, PhD
  • University of Kalyani, MS
  • University of Kalyani, BS

Publications

  • Published on 6/3/2021

    Kim D, Sesaki H, Roy S. Reduced Levels of Drp1 Protect against Development of Retinal Vascular Lesions in Diabetic Retinopathy. Cells. 2021 06 03; 10(6). PMID: 34204906.

    Read at: PubMed
  • Published on 5/31/2021

    Kim D, Votruba M, Roy S. Opa1 Deficiency Promotes Development of Retinal Vascular Lesions in Diabetic Retinopathy. Int J Mol Sci. 2021 May 31; 22(11). PMID: 34072974.

    Read at: PubMed
  • Published on 11/21/2020

    Herdade AS, Silva IM, Calado Â, Saldanha C, Nguyen NH, Hou I, Castanho M, Roy S. Effects of Diabetes on Microcirculation and Leukostasis in Retinal and Non-Ocular Tissues: Implications for Diabetic Retinopathy. Biomolecules. 2020 11 21; 10(11). PMID: 33233433.

    Read at: PubMed
  • Published on 11/19/2020

    Kim D, Lewis CS, Sarthy VP, Roy S. High-Glucose-Induced Rab20 Upregulation Disrupts Gap Junction Intercellular Communication and Promotes Apoptosis in Retinal Endothelial and Müller Cells: Implications for Diabetic Retinopathy. J Clin Med. 2020 Nov 19; 9(11). PMID: 33227912.

    Read at: PubMed
  • Published on 9/18/2020

    Roy S, Kim D. Retinal capillary basement membrane thickening: Role in the pathogenesis of diabetic retinopathy. Prog Retin Eye Res. 2021 05; 82:100903. PMID: 32950677.

    Read at: PubMed
  • Published on 8/3/2020

    Kim D, Roy S. Effects of Diabetes on Mitochondrial Morphology and Its Implications in Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2020 08 03; 61(10):10. PMID: 32756920.

    Read at: PubMed
  • Published on 7/10/2020

    Kim D, Sankaramoorthy A, Roy S. Downregulation of Drp1 and Fis1 Inhibits Mitochondrial Fission and Prevents High Glucose-Induced Apoptosis in Retinal Endothelial Cells. Cells. 2020 07 10; 9(7). PMID: 32664237.

    Read at: PubMed
  • Published on 4/9/2020

    Nguyen NH, Kim D, Roy S. High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2020 04 09; 61(4):40. PMID: 32340032.

    Read at: PubMed
  • Published on 9/21/2019

    Subramanian ML, Stein TD, Siegel N, Ness S, Fiorello MG, Kim D, Roy S. Upregulation of Lysyl Oxidase Expression in Vitreous of Diabetic Subjects: Implications for Diabetic Retinopathy. Cells. 2019 09 21; 8(10). PMID: 31546618.

    Read at: PubMed
  • Published on 9/16/2019

    Kim D, Lee D, Trackman PC, Roy S. Effects of High Glucose-Induced Lysyl Oxidase Propeptide on Retinal Endothelial Cell Survival: Implications for Diabetic Retinopathy. Am J Pathol. 2019 10; 189(10):1945-1952. PMID: 31537300.

    Read at: PubMed

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