Saravanan Subramaniam, PhD

Research Assistant Professor, Pulmonary Center

Saravanan Subramaniam
617.358.2800

Biography

Dr. Saravanan Subramaniam completed his bachelor and master degree in pharmacy and pharmacology from India and doctoral degree from Germany. He had completed his postdoctoral research at the center for thrombosis and hemostasis, Johannes Gutenberg University (Germany) and at McAllister Heart Institute, University of North Carolina (USA). He has published his research work in several high impact factor journals (Blood, circulation research, Hepatology, etc.,) and received several awards and travel grants. His area of specialization includes Intravital imaging of blood cells and coagulation.

Education

  • Justus Liebig Universitaet Giessen, PhD
  • Tamil Nadu Dr. M.G.R. Medical University, BPharm

Publications

  • Published on 7/13/2021

    Subramaniam S, Ogoti Y, Hernandez I, Zogg M, Botros F, Burns R, DeRousse JT, Dockendorff C, Mackman N, Antoniak S, Fletcher C, Weiler H. A thrombin-PAR1/2 feedback loop amplifies thromboinflammatory endothelial responses to the viral RNA analogue poly(I:C). Blood Adv. 2021 07 13; 5(13):2760-2774. PMID: 34242391.

    Read at: PubMed
  • Published on 7/7/2021

    Subramaniam S, Ruf W, Bosmann M. Advocacy of targeting protease-activated receptors in severe coronavirus disease 2019. Br J Pharmacol. 2021 Jul 07. PMID: 34235728.

    Read at: PubMed
  • Published on 10/22/2019

    Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice. mBio. 2019 10 22; 10(5). PMID: 31641089.

    Read at: PubMed
  • Published on 10/1/2019

    Subramaniam S, Boukhlouf S, Fletcher C. A bacterial metabolite, trimethylamine N-oxide, disrupts the hemostasis balance in human primary endothelial cells but no coagulopathy in mice. Blood Coagul Fibrinolysis. 2019 Oct; 30(7):324-330. PMID: 31490208.

    Read at: PubMed
  • Published on 9/24/2019

    Gao C, Schroeder JA, Xue F, Jing W, Cai Y, Scheck A, Subramaniam S, Rao S, Weiler H, Czechowicz A, Shi Q. Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice. Blood Adv. 2019 09 24; 3(18):2700-2711. PMID: 31515232.

    Read at: PubMed
  • Published on 6/29/2019

    Gandhi DM, Rosas R, Greve E, Kentala K, D-R Diby N, Snyder VA, Stephans A, Yeung THW, Subramaniam S, DiMilo E, Kurtenbach KE, Arnold LA, Weiler H, Dockendorff C. The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability. Bioorg Med Chem. 2019 09 01; 27(17):3788-3796. PMID: 31320211.

    Read at: PubMed
  • Published on 12/1/2018

    Subramaniam S, Kanse SM, Kothari H, Reinhardt C, Fletcher C. Post-transcriptional, post-translational and pharmacological regulation of tissue factor pathway inhibitor. Blood Coagul Fibrinolysis. 2018 Dec; 29(8):668-682. PMID: 30439766.

    Read at: PubMed
  • Published on 8/1/2018

    Etscheid M, Subramaniam S, Lochnit G, Zabczyk M, Undas A, Lang IM, Hanschmann KM, Kanse SM. Altered structure and function of fibrinogen after cleavage by Factor VII Activating Protease (FSAP). Biochim Biophys Acta Mol Basis Dis. 2018 10; 1864(10):3397-3406. PMID: 30076961.

    Read at: PubMed
  • Published on 5/17/2018

    Bode MF, Auriemma AC, Grover SP, Hisada Y, Rennie A, Bode WD, Vora R, Subramaniam S, Cooley B, Andrade-Gordon P, Antoniak S, Mackman N. The factor Xa inhibitor rivaroxaban reduces cardiac dysfunction in a mouse model of myocardial infarction. Thromb Res. 2018 07; 167:128-134. PMID: 29843086.

    Read at: PubMed
  • Published on 1/1/2018

    Subramaniam S, Scharrer I. Procoagulant activity during viral infections. Front Biosci (Landmark Ed). 2018 Jan 01; 23:1060-1081. PMID: 28930589.

    Read at: PubMed

View 12 more publications: View full profile at BUMC

View all profiles