Saravanan Subramaniam, PhD

Research Assistant Professor, Pulmonary Center

Saravanan Subramaniam
617.358.2800
72 East Concord Street

Biography

Dr. Saravanan Subramaniam completed his bachelor and master degree in pharmacy and pharmacology from India and doctoral degree from Germany. He had completed his postdoctoral research at the center for thrombosis and hemostasis, Johannes Gutenberg University (Germany) and at McAllister Heart Institute, University of North Carolina (USA). He has published his research work in several high impact factor journals (Blood, circulation research, Hepatology, etc.,) and received several awards and travel grants. His area of specialization includes Intravital imaging of blood cells and coagulation.

Education

  • Justus Liebig Universitaet Giessen, PhD
  • Tamil Nadu Dr. M.G.R. Medical University, BPharm

Publications

  • Published on 3/21/2022

    Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H. Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype. Front Cell Dev Biol. 2022; 10:852989. PMID: 35386206.

    Read at: PubMed
  • Published on 3/5/2022

    Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 03 05; 14(3). PMID: 35336942.

    Read at: PubMed
  • Published on 8/10/2021

    Eaton N, Subramaniam S, Schulte ML, Drew C, Jakab D, Haberichter SL, Weiler H, Falet H. Bleeding diathesis in mice lacking JAK2 in platelets. Blood Adv. 2021 08 10; 5(15):2969-2981. PMID: 34342643.

    Read at: PubMed
  • Published on 7/13/2021

    Subramaniam S, Ogoti Y, Hernandez I, Zogg M, Botros F, Burns R, DeRousse JT, Dockendorff C, Mackman N, Antoniak S, Fletcher C, Weiler H. A thrombin-PAR1/2 feedback loop amplifies thromboinflammatory endothelial responses to the viral RNA analogue poly(I:C). Blood Adv. 2021 07 13; 5(13):2760-2774. PMID: 34242391.

    Read at: PubMed
  • Published on 7/7/2021

    Subramaniam S, Ruf W, Bosmann M. Advocacy of targeting protease-activated receptors in severe coronavirus disease 2019. Br J Pharmacol. 2022 May; 179(10):2086-2099. PMID: 34235728.

    Read at: PubMed
  • Published on 1/15/2021

    Carossino M, Montanaro P, O'Connell A, Kenney D, Gertje H, Grosz KA, Kurnick SA, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal neuroinvasion of SARS-CoV-2 in K18-hACE2 mice is partially dependent on hACE2 expression. bioRxiv. 2021 Jan 15. PMID: 33469581.

    Read at: PubMed
  • Published on 10/22/2019

    Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice. mBio. 2019 10 22; 10(5). PMID: 31641089.

    Read at: PubMed
  • Published on 10/1/2019

    Subramaniam S, Boukhlouf S, Fletcher C. A bacterial metabolite, trimethylamine N-oxide, disrupts the hemostasis balance in human primary endothelial cells but no coagulopathy in mice. Blood Coagul Fibrinolysis. 2019 Oct; 30(7):324-330. PMID: 31490208.

    Read at: PubMed
  • Published on 9/24/2019

    Gao C, Schroeder JA, Xue F, Jing W, Cai Y, Scheck A, Subramaniam S, Rao S, Weiler H, Czechowicz A, Shi Q. Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice. Blood Adv. 2019 09 24; 3(18):2700-2711. PMID: 31515232.

    Read at: PubMed
  • Published on 6/29/2019

    Gandhi DM, Rosas R, Greve E, Kentala K, D-R Diby N, Snyder VA, Stephans A, Yeung THW, Subramaniam S, DiMilo E, Kurtenbach KE, Arnold LA, Weiler H, Dockendorff C. The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability. Bioorg Med Chem. 2019 09 01; 27(17):3788-3796. PMID: 31320211.

    Read at: PubMed

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