Samuel A. Ellias, MD, PhD

Associate Professor, Neurology

Samuel Ellias
72 E. Concord St Robinson (B)


Educational Background
Dr. Ellias obtained a Bachelor of Science in Physics from University of California at Los Angeles, and a Ph.D. in Applied Mathematics from Massachusetts Institute of Technology in 1974. He received an M.D. at University of Pennsylvania, School of Medicine in 1980 and completed neurological residency at Massachusetts General Hospital in 1984. He was a Neurological consultant at McLean Hospital. Subsequently, he was a Clinical Assistant in the Neurology Service at Massachusetts General Hospital and Instructor of Neurology at Harvard Medical School until 1990. He then served as an Assistant Professor Clinical Neurosciences, Brown University until 1993 when he joined the medical staff at Boston University and Boston University Medical Center.

He was a Kaplun Fellow of Applied Mathematics at the California Institute of Technology until 1976. He did research on the control of human movement from 1984 to 1990 as a Visiting Scientist in Brain & Cognitive Sciences at Massachusetts Institute of Technology

Clinical Care
Dr Ellias provides comprehensive care to patients with a diagnosis of Parkinson’s disease or other movement disorders. As Neurological Director of the Deep Brain Stimulation Program he is actively involved in patient selection, evaluation, and care of individuals referred for Deep Brain Stimulation in Parkinson’s Disease, essential tremor, and dystonia.

He has conducted Parkinson’s disease research studying clinical outcomes and the neurophysiology of Deep Brain Stimulation, Pig Cell Xenotransplantation, and Retinal Pigment Epithelial Cell Transplantation. He has conducted Phase II and Phase III clinical trials for the medical treatment of Parkinson’s disease. He has done primary research on Essential tremor and tremors secondary to toxic exposure.

Dr. Ellias is Involved in the teaching of medical students, residents, and the movement disorder fellow in the Department of Neurology.

Professional Affiliations
He is a member of the Movement Disorders Society, American Academy of Neurology, Society for Neuroscience, Massachusetts Neurological Association, and the International Tremor Foundation. He is a researcher and clinical investigator in the Parkinson’s Study Group. Dr. Ellias has served on the New England/Neurosurgery Advisory Work Group on Deep Brain Stimulation for the Carrier Advisory Committee.


  • University of Pennsylvania, MD
  • Massachusetts Institute of Technology, PhD
  • University of California, Los Angeles, BS


  • Published on 5/1/2014

    Beal MF, Oakes D, Shoulson I, Henchcliffe C, Galpern WR, Haas R, Juncos JL, Nutt JG, Voss TS, Ravina B, Shults CM, Helles K, Snively V, Lew MF, Griebner B, Watts A, Gao S, Pourcher E, Bond L, Kompoliti K, Agarwal P, Sia C, Jog M, Cole L, Sultana M, Kurlan R, Richard I, Deeley C, Waters CH, Figueroa A, Arkun A, Brodsky M, Ondo WG, Hunter CB, Jimenez-Shahed J, Palao A, Miyasaki JM, So J, Tetrud J, Reys L, Smith K, Singer C, Blenke A, Russell DS, Cotto C, Friedman JH, Lannon M, Zhang L, Drasby E, Kumar R, Subramanian T, Ford DS, Grimes DA, Cote D, Conway J, Siderowf AD, Evatt ML, Sommerfeld B, Lieberman AN, Okun MS, Rodriguez RL, Merritt S, Swartz CL, Martin WR, King P, Stover N, Guthrie S, Watts RL, Ahmed A, Fernandez HH, Winters A, Mari Z, Dawson TM, Dunlop B, Feigin AS, Shannon B, Nirenberg MJ, Ogg M, Ellias SA, Thomas CA, Frei K, Bodis-Wollner I, Glazman S, Mayer T, Hauser RA, Pahwa R, Langhammer A, Ranawaya R, Derwent L, Sethi KD, Farrow B, Prakash R, Litvan I, Robinson A, Sahay A, Gartner M, Hinson VK, Markind S, Pelikan M, Perlmutter JS, Hartlein J, Molho E, Evans S, Adler CH, Duffy A, Lind M, Elmer L, Davis K, Spears J, Wilson S, Leehey MA, Hermanowicz N, Niswonger S, Shill HA, Obradov S, Rajput A, Cowper M, Lessig S, Song D, Fontaine D, Zadikoff C, Williams K, Blindauer KA, Bergholte J, Propsom CS, Stacy MA, Field J, Mihaila D, Chilton M, Uc EY, Sieren J, Simon DK, Kraics L, Silver A, Boyd JT, Hamill RW, Ingvoldstad C, Young J, Thomas K, Kostyk SK, Wojcieszek J, Pfeiffer RF, Panisset M, Beland M, Reich SG, Cines M, Zappala N, Rivest J, Zweig R, Lumina LP, Hilliard CL, Grill S, Kellermann M, Tuite P, Rolandelli S, Kang UJ, Young J, Rao J, Cook MM, Severt L, Boyar K. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014 May; 71(5):543-52. PMID: 24664227.

    Read at: PubMed
  • Published on 10/6/2009

    Daniluk S, G Davies K, Ellias SA, Novak P, Nazzaro JM. Assessment of the variability in the anatomical position and size of the subthalamic nucleus among patients with advanced Parkinson's disease using magnetic resonance imaging. Acta Neurochir (Wien). 2010 Feb; 152(2):201-10; discussion 210. PMID: 19806309.

    Read at: PubMed
  • Published on 5/1/2009

    Daniluk S, Davies KG, Novak P, Vu T, Nazzaro JM, Ellias SA. Isolation of the brain-related factor of the error between intended and achieved position of deep brain stimulation electrodes implanted into the subthalamic nucleus for the treatment of Parkinson's disease. Neurosurgery. 2009 May; 64(5 Suppl 2):374-82; discussion 382-4. PMID: 19404117.

    Read at: PubMed
  • Published on 1/1/2007

    Novak P, Daniluk S, Ellias SA, Nazzaro JM. Detection of the subthalamic nucleus in microelectrographic recordings in Parkinson disease using the high-frequency (> 500 hz) neuronal background. Technical note. J Neurosurg. 2007 Jan; 106(1):175-9. PMID: 17236505.

    Read at: PubMed
  • Published on 3/14/2000

    Schumacher JM, Ellias SA, Palmer EP, Kott HS, Dinsmore J, Dempsey PK, Fischman AJ, Thomas C, Feldman RG, Kassissieh S, Raineri R, Manhart C, Penney D, Fink JS, Isacson O. Transplantation of embryonic porcine mesencephalic tissue in patients with PD. Neurology. 2000 Mar 14; 54(5):1042-50. PMID: 10720272.

    Read at: PubMed
  • Published on 12/1/1999

    Biernat H, Ellias SA, Wermuth L, Cleary D, de Oliveira Santos EC, Jørgensen PJ, Feldman RG, Grandjean P. Tremor frequency patterns in mercury vapor exposure, compared with early Parkinson's disease and essential tremor. Neurotoxicology. 1999 Dec; 20(6):945-52. PMID: 10693975.

    Read at: PubMed
  • Published on 1/1/1995

    Ott BR, Ellias SA, Lannon MC. Quantitative assessment of movement in Alzheimer's disease. J Geriatr Psychiatry Neurol. 1995 Jan; 8(1):71-5. PMID: 7710652.

    Read at: PubMed
  • Published on 11/1/1993

    Ellias SA. Essential tremor. R I Med. 1993 Nov; 76(11):563-6. PMID: 8312634.

    Read at: PubMed
  • Published on 9/8/1980

    Ellias SA, Stevens JK. The dendritic varicosity: a mechanism for electrically isolating the dendrites of cat retinal amacrine cells? Brain Res. 1980 Sep 8; 196(2):365-72. PMID: 6249448.

    Read at: PubMed
  • Published on 5/1/1980

    Rothschild KJ, Ellias SA, Essig A, Stanley HE. Nonequilibrium linear behavior of biological systems. Existence of enzyme-mediated multidimensional inflection points. Biophys J. 1980 May; 30(2):209-30. PMID: 7260273.

    Read at: PubMed

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