Rutao Cui, MD, PhD

Professor, Pharmacology & Experimental Therapeutics

Rutao Cui
617.358.4963
72 E. Concord St Housman (R)

Biography

Dr. Cui’s primary research interests include: understanding molecular mechanisms of melanoma development, defining the molecular effects of UVB radiation on melanocyte growth and differentiation, and developing murine genetic models for human melanoma.

Other Positions

  • Professor, Dermatology, Boston University School of Medicine

Education

  • Shandong Medical University, MD
  • Shanghai Medical University, PhD

Classes Taught

Publications

  • Published on 2/20/2019

    Chen S, Han C, Miao X, Li X, Yin C, Zou J, Liu M, Li S, Stawski L, Zhu B, Shi Q, Xu ZX, Li C, Goding CR, Zhou J, Cui R. Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads. Nat Commun. 2019 02 20; 10(1):877. PMID: 30787281.

    Read at: PubMed
  • Published on 1/31/2019

    Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, Li X, Miao X, Li S, Mi X, Zhang J, Li L, Wei G, Xu ZX, Gao X, Huang C, Wei Z, Goding CR, Wang P, Deng X, Cui R. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. 2019 Feb 21; 176(5):1113-1127.e16. PMID: 30712867.

    Read at: PubMed
  • Published on 5/22/2018

    Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, Liu T, Liu W, Han C, Stawski L, Xu ZX, Zhou G, Chen X, Gao X, Goding CR, Xu N, Cui R, Cao P. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018 09; 37(36):4941-4954. PMID: 29786078.

    Read at: PubMed
  • Published on 1/17/2018

    Zhu B, Chen S, Wang H, Yin C, Han C, Peng C, Liu Z, Wan L, Zhang X, Zhang J, Lian CG, Ma P, Xu ZX, Prince S, Wang T, Gao X, Shi Y, Liu D, Liu M, Wei W, Wei Z, Pan J, Wang Y, Xuan Z, Hess J, Hayward NK, Goding CR, Chen X, Zhou J, Cui R. The protective role of DOT1L in UV-induced melanomagenesis. Nat Commun. 2018 01 17; 9(1):259. PMID: 29343685.

    Read at: PubMed
  • Published on 1/10/2018

    Miao X, Chen S, Zhu B, Yin C, Li X, Han C, Cui R, Li B. Are redheads at an increased risk of melanoma? Future Oncol. 2018 Feb; 14(5):413-416. PMID: 29318914.

    Read at: PubMed
  • Published on 9/6/2017

    Chen S, Zhu B, Yin C, Liu W, Han C, Chen B, Liu T, Li X, Chen X, Li C, Hu L, Zhou J, Xu ZX, Gao X, Wu X, Goding CR, Cui R. Palmitoylation-dependent activation of MC1R prevents melanomagenesis. Nature. 2017 09 21; 549(7672):399-403. PMID: 28869973.

    Read at: PubMed
  • Published on 2/7/2017

    Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, Song SJ, Lu Y, Liu J, Inuzuka H, Katon JM, Berry K, Fung J, Ng C, Liu P, Song MS, Xue L, Bronson RT, Kirschner MW, Cui R, Pandolfi PP, Wei W. The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function. Cancer Discov. 2017 Apr; 7(4):424-441. PMID: 28174173.

    Read at: PubMed
  • Published on 11/8/2016

    Wang YS, Chen J, Cui F, Wang H, Wang S, Hang W, Zeng Q, Quan CS, Zhai YX, Wang JW, Shen XF, Jian YP, Zhao RX, Werle KD, Cui R, Liang J, Li YL, Xu ZX. LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors. Oncotarget. 2016 Nov 08; 7(45):73389-73401. PMID: 27705915.

    Read at: PubMed
  • Published on 8/1/2016

    Zeng Q, Zhao RX, Chen J, Li Y, Li XD, Liu XL, Zhang WM, Quan CS, Wang YS, Zhai YX, Wang JW, Youssef M, Cui R, Liang J, Genovese N, Chow LT, Li YL, Xu ZX. O-linked GlcNAcylation elevated by HPV E6 mediates viral oncogenesis. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):9333-8. PMID: 27482104.

    Read at: PubMed
  • Published on 7/12/2016

    Robles-Espinoza CD, Roberts ND, Chen S, Leacy FP, Alexandrov LB, Pornputtapong N, Halaban R, Krauthammer M, Cui R, Timothy Bishop D, Adams DJ. Germline MC1R status influences somatic mutation burden in melanoma. Nat Commun. 2016 07 12; 7:12064. PMID: 27403562.

    Read at: PubMed

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