Richard D. Wainford, PhD

Associate Professor, Pharmacology & Experimental Therapeutics

Richard Wainford
700 Albany St Ctr for Adv Biomed Res


Dr Wainford obtained a Bachelors in Zoology from the University of Wales, Cardiff in 1999. Dr Wainford undertook his Graduate training in the Laboratory of Molecular Pharmacology and Toxicology in the Department of Medicine and Therapeutics at the University of Aberdeen School of Medicine under the guidance of Professor Hawksworth, earning a PhD in Molecular Pharmacology in 2004. Dr. Wainford then completed a 2-year post-doctoral fellowship in the Department of Pharmacology at the Louisiana State University Health Sciences Center in New Orleans in Cardiovascular & Renal Pharmacology under the mentorship of Dr. Kapusta. Dr. Wainford then became an Instructor of Pharmacology in 2008, remaining in the laboratory of Dr. Kapusta until his promotion to the rank of Assistant Professor in 2010. Dr. Wainford joined the Department of Pharmacology & Experimental Therapeutics at the Boston University School of Medicine and the Whitaker Cardiovascular Institute in 2011 as an Assistant Professor.

Research Summary:
Dr. Wainford is the director of the Laboratory of Cardio-Renal Research. Dr. Wainford’s research interests focus on the central neural control of fluid and electrolyte homeostasis and blood pressure regulation. Dr. Wainford’s laboratory utilizes an integrated physiological, pharmacological, molecular, and gene-targeting approach to investigate the anti-hypertensive role(s) of central G-alpha-subunit proteins in the endogenous GPCR-activated pathways that regulate central sympatheticoutflow, fluid and electrolyte homeostasis, and systemic blood pressure regulation in salt-resistant and salt-sensitive animal models.The major goal of Dr. Wainford’s research is identifying the underlying pathophysiology of and potential treatments for hypertension. Current studies concern the role of central G-alpha subunit protein gated pathways in mediating the neural control of kidney function and systemic arterial blood pressure.

Other Positions

  • Associate Professor, Cardiovascular Medicine, Medicine, Boston University School of Medicine


  • University of Aberdeen, PhD
  • University of Wales, BS


  • Published on 5/27/2019

    Frame AA, Carmichael CY, Kuwabara JT, Cunningham JT, Wainford RD. Role of the afferent renal nerves in sodium homeostasis and blood pressure regulation in rats. Exp Physiol. 2019 Aug; 104(8):1306-1323. PMID: 31074108.

    Read at: PubMed
  • Published on 4/24/2019

    Poulter NR, Borghi C, Castillo RR, Charchar FJ, Ramirez AJ, Schlaich MP, Schutte AE, Stergiou G, Unger T, Wainford RD, Beaney T. May Measurement Month 2017: Results of 39 national blood pressure screening programmes. Eur Heart J Suppl. 2019 Apr; 21(Suppl D):D1-D4. PMID: 31043862.

    Read at: PubMed
  • Published on 6/15/2018

    Zhang X, Frame AA, Williams JS, Wainford RD. GNAI2 polymorphic variance associates with salt sensitivity of blood pressure in the Genetic Epidemiology Network of Salt Sensitivity study. Physiol Genomics. 2018 09 01; 50(9):724-725. PMID: 29906209.

    Read at: PubMed
  • Published on 2/14/2018

    Frame AA, Wainford RD. Mechanisms of altered renal sodium handling in age-related hypertension. Am J Physiol Renal Physiol. 2018 07 01; 315(1):F1-F6. PMID: 29442548.

    Read at: PubMed
  • Published on 10/31/2017

    Wainford RD. How to Reduce Dietary Salt Intake: Just Add Spice? Hypertension. 2017 12; 70(6):1087-1088. PMID: 29089369.

    Read at: PubMed
  • Published on 6/30/2017

    Frame AA, Wainford RD. Renal sodium handling and sodium sensitivity. Kidney Res Clin Pract. 2017 Jun; 36(2):117-131. PMID: 28680820.

    Read at: PubMed
  • Published on 9/1/2016

    Wainford R, Carmichael C, Walsh K. OS 11-01 Afferent renal nerve modulation of sodium homeostasis and blood pressure: A sodium sensitive PVN Gai2 protein dependent mechanism countering the development of salt-sensitive hypertension? J Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book:e74. PMID: 27753968.

    Read at: PubMed
  • Published on 9/1/2016

    Wainford R, Walsh K. OS 29-04 SYMPATHETIC NERVOUS SYSTEM REGULATION OF THE RENAL NCC AND BLOOD PRESSURE DURING HIGH DIETARY SALT INTAKE. J Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book:e253-e254. PMID: 27754152.

    Read at: PubMed
  • Published on 9/1/2016

    Wainford R. ED 09-1 RENAL SODIUM HANDLING AND SALT SENSITIVITY. J Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book:e537. PMID: 27754276.

    Read at: PubMed
  • Published on 9/1/2016

    Frame AA, Carmichael CY, Wainford RD. Renal Afferents. Curr Hypertens Rep. 2016 Sep; 18(9):69. PMID: 27595156.

    Read at: PubMed

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