Richard D. Wainford, PhD

Associate Professor, Pharmacology & Experimental Therapeutics

Richard Wainford
617.358.8238
700 Albany St Ctr for Adv Biomed Res

Biography

Background:
Dr Wainford obtained a Bachelors in Zoology from the University of Wales, Cardiff in 1999. Dr Wainford undertook his Graduate training in the Laboratory of Molecular Pharmacology and Toxicology in the Department of Medicine and Therapeutics at the University of Aberdeen School of Medicine under the guidance of Professor Hawksworth, earning a PhD in Molecular Pharmacology in 2004. Dr. Wainford then completed a 2-year post-doctoral fellowship in the Department of Pharmacology at the Louisiana State University Health Sciences Center in New Orleans in Cardiovascular & Renal Pharmacology under the mentorship of Dr. Kapusta. Dr. Wainford then became an Instructor of Pharmacology in 2008, remaining in the laboratory of Dr. Kapusta until his promotion to the rank of Assistant Professor in 2010. Dr. Wainford joined the Department of Pharmacology & Experimental Therapeutics at the Boston University School of Medicine and the Whitaker Cardiovascular Institute in 2011 as an Assistant Professor.

Research Summary:
Dr. Wainford is the director of the Laboratory of Cardio-Renal Research. Dr. Wainford’s research interests focus on the central neural control of fluid and electrolyte homeostasis and blood pressure regulation. Dr. Wainford’s laboratory utilizes an integrated physiological, pharmacological, molecular, and gene-targeting approach to investigate the anti-hypertensive role(s) of central G-alpha-subunit proteins in the endogenous GPCR-activated pathways that regulate central sympatheticoutflow, fluid and electrolyte homeostasis, and systemic blood pressure regulation in salt-resistant and salt-sensitive animal models.The major goal of Dr. Wainford’s research is identifying the underlying pathophysiology of and potential treatments for hypertension. Current studies concern the role of central G-alpha subunit protein gated pathways in mediating the neural control of kidney function and systemic arterial blood pressure.

Other Positions

  • Associate Professor, Cardiovascular Medicine, Medicine, Boston University School of Medicine
  • Member, Whitaker Cardiovascular Institute, Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences

Education

  • University of Aberdeen, PhD
  • University of Wales, BS

Classes Taught

  • GMSPM701

Publications

  • Published on 7/1/2021

    Farris CW, Killiany RJ, O'Donoghue E, Koo BB, Wainford RD, Moss MB, Rosene DL, Moore TL. The relationship of age and hypertension with cognition and gray matter cerebral blood volume in a rhesus monkey model of human aging. Behav Neurosci. 2021 Jul 01. PMID: 34197136.

    Read at: PubMed
  • Published on 5/17/2021

    Chaudhary P, Velkoska E, Wainford RD. An exploratory analysis of comparative plasma metabolomic and lipidomic profiling in salt-sensitive and salt-resistant individuals from The Dietary Approaches to Stop Hypertension Sodium Trial. J Hypertens. 2021 May 17. PMID: 34001808.

    Read at: PubMed
  • Published on 2/16/2021

    Gnanenthiran SR, Borghi C, Burger D, Charchar F, Poulter NR, Schlaich MP, Steckelings UM, Stergiou G, Tomaszewski M, Unger T, Wainford RD, Williams B, Rodgers A, Schutte AE. Prospective meta-analysis protocol on randomised trials of renin-angiotensin system inhibitors in patients with COVID-19: an initiative of the International Society of Hypertension. BMJ Open. 2021 02 16; 11(2):e043625. PMID: 33593784.

    Read at: PubMed
  • Published on 11/30/2020

    Chaudhary P, Wainford RD. Neuroanatomical characterization of Gai2-expressing neurons in the hypothalamic paraventricular nucleus of male and female Sprague-Dawley rats. Physiol Genomics. 2021 01 01; 53(1):12-21. PMID: 33252993.

    Read at: PubMed
  • Published on 9/28/2020

    Puleo F, Kim K, Frame AA, Walsh KR, Ferdaus MZ, Moreira JD, Comsti E, Faudoa E, Nist KM, Abkin E, Wainford RD. Sympathetic Regulation of the NCC (Sodium Chloride Cotransporter) in Dahl Salt-Sensitive Hypertension. Hypertension. 2020 11; 76(5):1461-1469. PMID: 32981364.

    Read at: PubMed
  • Published on 8/28/2020

    Poulter NR, Borghi C, Burger D, Castillo RR, Damasceno A, Ito S, Jose AP, Kruger R, Morgan T, Nilsson PM, Schlaich MP, Schutte AE, Stergiou G, Unger T, Wainford RD, Beaney T. May Measurement Month 2018: results of blood pressure screening from 41 countries. Eur Heart J Suppl. 2020 Aug; 22(Suppl H):H1-H4. PMID: 32884454.

    Read at: PubMed
  • Published on 7/13/2020

    Chaudhary P, Wainford RD. Association of urinary sodium and potassium excretion with systolic blood pressure in the Dietary Approaches to Stop Hypertension Sodium Trial. J Hum Hypertens. 2021 Jul; 35(7):577-587. PMID: 32661268.

    Read at: PubMed
  • Published on 6/1/2020

    Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, Ramirez A, Schlaich M, Stergiou GS, Tomaszewski M, Wainford RD, Williams B, Schutte AE. 2020 International Society of Hypertension global hypertension practice guidelines. J Hypertens. 2020 06; 38(6):982-1004. PMID: 32371787.

    Read at: PubMed
  • Published on 5/18/2020

    Beaney T, Schutte AE, Stergiou GS, Borghi C, Burger D, Charchar F, Cro S, Diaz A, Damasceno A, Espeche W, Jose AP, Khan N, Kokubo Y, Maheshwari A, Marin MJ, More A, Neupane D, Nilsson P, Patil M, Prabhakaran D, Ramirez A, Rodriguez P, Schlaich M, Steckelings UM, Tomaszewski M, Unger T, Wainford R, Wang J, Williams B, Poulter NR. May Measurement Month 2019: The Global Blood Pressure Screening Campaign of the International Society of Hypertension. Hypertension. 2020 08; 76(2):333-341. PMID: 32419505.

    Read at: PubMed
  • Published on 5/6/2020

    Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, Ramirez A, Schlaich M, Stergiou GS, Tomaszewski M, Wainford RD, Williams B, Schutte AE. 2020 International Society of Hypertension Global Hypertension Practice Guidelines. Hypertension. 2020 06; 75(6):1334-1357. PMID: 32370572.

    Read at: PubMed

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