Philip A. Wolf, MD

Professor, Neurology

Philip Wolf
72 E. Concord St Robinson (B)


Dr. Philip A. Wolf received his medical degree from the State University of New York College of Medicine at Syracuse, and completed his residency at the Massachusetts General Hospital in Boston. He is Professor of Neurology, Research Professor of Medicine (Epidemiology and Preventive Medicine), Boston University School of Medicine, and Professor of Public Health (Epidemiology and Biostatistics) at Boston University School of Public Health. He was Co-Principal Investigator on The Framingham Heart Study Physical Examination, Testing and Surveillance awarded by the NHLBI to Boston University School of Medicine from 1983 to 1989, and has been Principal Investigator since 1989. Dr. Wolf continues as Principal Investigator on the current contract which runs through September 2014.

In 2002 he stepped down from the post of Chief of the Cerebrovascular Disease Section of the Department of Neurology at Boston University Medical Center, a post he held for more than 30 years. In that role he participated in a number of international cooperative clinical studies of stroke, He was a PI or Executive Committee member for several key projects: The National Institute of Neurological Disorders and Stroke (NINDS) Data Bank; The Ticlopidine-Aspirin Stroke Study (TASS); Boston Area Anticoagulation Trial in Atrial Fibrillation (BAATAF); North American Symptomatic Carotid Endarterectomy Trial (NASCET); and, the Clopidogrel-Aspirin Prevention of Ischemic Events Study (CAPRIE).

He has served on Executive Committees and Data Safety Monitoring Boards for a number of NIH and industry supported studies of Stroke: BRAVO, VISP, TRENDS, WHI Stroke Study, and PRoFESS. He serves on the Monitoring Boards of two NHLBI observational studies, the Cardiovascular Health Study and The Jackson Heart Study. He is a member of the Stroke Council and Epidemiology and Disease Prevention Councils of the American Heart Association and served on the Executive Committees of both councils. He was a member of the Science Affairs Council of the American Heart Association and of the Scientific Issues Committee of the American Academy of Neurology.

In 1992, he was selected by the National Advisory Neurological Disorders and Stroke Council to receive a Jacob A. Javits Neuroscience Investigator Award and was the first to receive the Humana Award for Excellence in Clinical Stroke of the Stroke Council of the American Heart Association. He was selected as the Connor Memorial Lecturer in 1992 by the American Heart Association. He also received the Mihara Cerebrovascular Disorder Research Fund Mihara Award of the International Stroke Society in 1996. He was the recipient of the American Stroke Association New England Chapter’s C. Miller Fisher Award in 2000.

Dr. Wolf’s publications are largely focused on the topics of the epidemiology of stroke, dementia and cognitive decline and he has authored or co-authored over 500 refereed articles, book chapters, and abstracts. His research has appeared in such journals as The New England Journal of Medicine, Journal of the American Medical Association, Neurology, Stroke, and The American Journal of Epidemiology. He has served on the editorial boards of Stroke-A Journal of Cerebral Circulation, Neuroepidemiology, American Journal of Geriatric Cardiology, Journal of Cardiovascular Risk, and the Journal of Thrombosis and Thrombolysis.

He has been elected to a number of professional associations including the American Neurologic Association, the American Epidemiologic Society, the American Academy of Neurology, the American Heart Association, American College of Epidemiology, and the Council on Geriatric Cardiology.

Other Positions

  • Principal Investigator, Framingham Heart Study
  • Boston Medical Center


  • State University of New York Upstate Medical University, MD
  • New York University, AB


  • Published on 1/1/2018

    Bangen KJ, Preis SR, Delano-Wood L, Wolf PA, Libon DJ, Bondi MW, Au R, DeCarli C, Brickman AM. Baseline White Matter Hyperintensities and Hippocampal Volume are Associated With Conversion From Normal Cognition to Mild Cognitive Impairment in the Framingham Offspring Study. Alzheimer Dis Assoc Disord. 2018 Jan-Mar; 32(1):50-56. PMID: 28984639.

    Read at: PubMed
  • Published on 6/24/2017

    Aparicio HJ, Himali JJ, Beiser AS, Davis-Plourde KL, Vasan RS, Kase CS, Wolf PA, Seshadri S. Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study. J Am Heart Assoc. 2017 Jun 24; 6(6). PMID: 28647687.

    Read at: PubMed
  • Published on 6/23/2017

    Aparicio HJ, Petrea RE, Massaro JM, Manning WJ, Oyama-Manabe N, Beiser AS, Kase CS, D'Agostino RB, Wolf PA, Vasan RS, DeCarli C, O'Donnell CJ, Seshadri S. Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study. Atherosclerosis. 2017 Oct; 265:305-311. PMID: 28673480.

    Read at: PubMed
  • Published on 6/13/2017

    Li J, Ogrodnik M, Devine S, Auerbach S, Wolf PA, Au R. Practical risk score for 5-, 10-, and 20-year prediction of dementia in elderly persons: Framingham Heart Study. Alzheimers Dement. 2018 Jan; 14(1):35-42. PMID: 28627378.

    Read at: PubMed
  • Published on 2/3/2017

    Dufouil C, Beiser A, McLure LA, Wolf PA, Tzourio C, Howard VJ, Westwood AJ, Himali JJ, Sullivan L, Aparicio HJ, Kelly-Hayes M, Ritchie K, Kase CS, Pikula A, Romero JR, D'Agostino RB, Samieri C, Vasan RS, ChĂȘne G, Howard G, Seshadri S. Revised Framingham Stroke Risk Profile to Reflect Temporal Trends. Circulation. 2017 Mar 21; 135(12):1145-1159. PMID: 28159800.

    Read at: PubMed
  • Published on 1/31/2017

    Romero JR, Preis SR, Beiser A, Himali JJ, Shoamanesh A, Wolf PA, Kase CS, Vasan RS, DeCarli C, Seshadri S. Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study. Stroke. 2017 Mar; 48(3):781-783. PMID: 28143923.

    Read at: PubMed
  • Published on 1/12/2017

    Lubitz SA, Yin X, McManus DD, Weng LC, Aparicio HJ, Walkey AJ, Rafael Romero J, Kase CS, Ellinor PT, Wolf PA, Seshadri S, Benjamin EJ. Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study. Stroke. 2017 Feb; 48(2):490-492. PMID: 28082669.

    Read at: PubMed
  • Published on 8/24/2016

    Shoamanesh A, Preis SR, Beiser AS, Kase CS, Wolf PA, Vasan RS, Benjamin EJ, Seshadri S, Romero JR. Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study. Neurology. 2016 Sep 20; 87(12):1206-11. PMID: 27558379.

    Read at: PubMed
  • Published on 7/11/2016

    Piers RJ, Nishtala A, Preis SR, DeCarli C, Wolf PA, Benjamin EJ, Au R. Association between atrial fibrillation and volumetric magnetic resonance imaging brain measures: Framingham Offspring Study. Heart Rhythm. 2016 Oct; 13(10):2020-4. PMID: 27417740.

    Read at: PubMed
  • Published on 7/6/2016

    Bangen KJ, Himali JJ, Beiser AS, Nation DA, Libon DJ, Fox CS, Seshadri S, Wolf PA, McKee AC, Au R, Delano-Wood L. Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimer's Disease Pathology. J Alzheimers Dis. 2016 07 06; 53(4):1553-62. PMID: 27392855.

    Read at: PubMed

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