Lynne M. Coluccio, PhD

Associate Professor, Physiology & Biophysics

Lynne Coluccio
617.358.8447
700 Albany St Ctr for Adv Biomed Res

Biography

Lynne Coluccio, PhD, began her career at Boston University as a Principal Scientist at the Boston Biomedical Research Institute (BBRI) in 1996. After the institute was closed in 2013, she became a Research Associate in the Department of Physiology & Biophysics at the Boston University School of Medicine and has remained since then. While at the BBRI, she played a variety of roles on the committee including as a chair of the Faculty Search Committee and as a member of the Public Relations Committee. Throughout her she career she has mentored dozens of students who have gone into academia, medicine, teaching, and music.

Education

  • Rensselaer Polytechnic Institute, PhD
  • Rensselaer Polytechnic Institute, MS
  • State University of New York at Albany, BS

Publications

  • Published on 7/11/2018

    Tokuo H, Bhawan J, Coluccio LM. Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis. Sci Rep. 2018 Jul 11; 8(1):10449. PMID: 29993000.

    Read at: PubMed
  • Published on 9/11/2015

    Komaba S, Coluccio LM. Myosin 1b Regulates Amino Acid Transport by Associating Transporters with the Apical Plasma Membrane of Kidney Cells. PLoS One. 2015; 10(9):e0138012. PMID: 26361046.

    Read at: PubMed
  • Published on 7/17/2013

    Tokuo H, Coluccio LM. Myosin-1c regulates the dynamic stability of E-cadherin-based cell-cell contacts in polarized Madin-Darby canine kidney cells. Mol Biol Cell. 2013 Sep; 24(18):2820-33. PMID: 23864705.

    Read at: PubMed
  • Published on 6/16/2011

    Chinthalapudi K, Taft MH, Martin R, Heissler SM, Preller M, Hartmann FK, Brandstaetter H, Kendrick-Jones J, Tsiavaliaris G, Gutzeit HO, Fedorov R, Buss F, Knölker HJ, Coluccio LM, Manstein DJ. Mechanism and specificity of pentachloropseudilin-mediated inhibition of myosin motor activity. J Biol Chem. 2011 Aug 26; 286(34):29700-8. PMID: 21680745.

    Read at: PubMed
  • Published on 7/17/2010

    Adamek N, Geeves MA, Coluccio LM. Myo1c mutations associated with hearing loss cause defects in the interaction with nucleotide and actin. Cell Mol Life Sci. 2011 Jan; 68(1):139-50. PMID: 20640478.

    Read at: PubMed
  • Published on 7/7/2010

    Komaba S, Coluccio LM. Localization of myosin 1b to actin protrusions requires phosphoinositide binding. J Biol Chem. 2010 Sep 3; 285(36):27686-93. PMID: 20610386.

    Read at: PubMed
  • Published on 2/9/2010

    Adamek N, Lieto-Trivedi A, Geeves MA, Coluccio LM. Modification of loop 1 affects the nucleotide binding properties of Myo1c, the adaptation motor in the inner ear. Biochemistry. 2010 Feb 9; 49(5):958-71. PMID: 20039646.

    Read at: PubMed
  • Published on 1/1/2010

    Wang CL, Coluccio LM. New insights into the regulation of the actin cytoskeleton by tropomyosin. Int Rev Cell Mol Biol. 2010; 281:91-128. PMID: 20460184.

    Read at: PubMed
  • Published on 8/26/2008

    Lieto-Trivedi A, Coluccio LM. Calcium, nucleotide, and actin affect the interaction of mammalian Myo1c with its light chain calmodulin. Biochemistry. 2008 Sep 23; 47(38):10218-26. PMID: 18729383.

    Read at: PubMed
  • Published on 4/7/2008

    Adamek N, Coluccio LM, Geeves MA. Calcium sensitivity of the cross-bridge cycle of Myo1c, the adaptation motor in the inner ear. Proc Natl Acad Sci U S A. 2008 Apr 15; 105(15):5710-5. PMID: 18391215.

    Read at: PubMed

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