John R. Murphy, PhD

Professor, Medicine

John Murphy
650 Albany St Evans Biomed Research Ctr

Other Positions

  • Professor, Microbiology, Boston University School of Medicine
  • Mentor for Graduate Medical Students, Boston University School of Medicine, Division of Graduate Medical Sciences
  • Boston Medical Center


  • University of Connecticut, PhD
  • University of Connecticut, MS
  • University of Connecticut, BA


  • Published on 6/15/2017

    Gupta S, Cheung L, Pokkali S, Winglee K, Guo H, Murphy JR, Bishai WR. Suppressor Cell-Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis. J Infect Dis. 2017 Jun 15; 215(12):1883-1887. PMID: 28863467.

    Read at: PubMed
  • Published on 7/29/2011

    Tamayo AG, Slater L, Taylor-Parker J, Bharti A, Harrison R, Hung DT, Murphy JR. GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro. Mol Microbiol. 2011 Sep; 81(5):1390-401. PMID: 21797942.

    Read at: PubMed
  • Published on 4/14/2011

    Wan ES, Hokanson JE, Murphy JR, Regan EA, Make BJ, Lynch DA, Crapo JD, Silverman EK. Clinical and radiographic predictors of GOLD-unclassified smokers in the COPDGene study. Am J Respir Crit Care Med. 2011 Jul 1; 184(1):57-63. PMID: 21493737.

    Read at: PubMed
  • Published on 3/21/2011

    Murphy JR. Mechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process. Toxins (Basel). 2011 Mar; 3(3):294-308. PMID: 22069710.

    Read at: PubMed
  • Published on 2/18/2011

    Lasalle-Williams M, Nuss R, Le T, Cole L, Hassell K, Murphy JR, Ambruso DR. Extended red blood cell antigen matching for transfusions in sickle cell disease: a review of a 14-year experience from a single center (CME). Transfusion. 2011 Aug; 51(8):1732-9. PMID: 21332724.

    Read at: PubMed
  • Published on 1/1/2011

    Phasomkusolsil S, Lerdthusnee K, Khuntirat B, Kongtak W, Pantuwatana K, Murphy JR. Effect of temperature on laboratory reared Anopheles dirus Peyton and Harrison and Anopheles sawadwongporni Rattanarithikul and Green. Southeast Asian J Trop Med Public Health. 2011 Jan; 42(1):63-70. PMID: 21323167.

    Read at: PubMed
  • Published on 4/14/2010

    Trujillo C, Taylor-Parker J, Harrison R, Murphy JR. Essential lysine residues within transmembrane helix 1 of diphtheria toxin facilitate COPI binding and catalytic domain entry. Mol Microbiol. 2010 May; 76(4):1010-9. PMID: 20398220.

    Read at: PubMed
  • Published on 9/5/2008

    Wright DG, Zhang Y, Murphy JR. Effective delivery of antisense peptide nucleic acid oligomers into cells by anthrax protective antigen. Biochem Biophys Res Commun. 2008 Nov 7; 376(1):200-5. PMID: 18774771.

    Read at: PubMed
  • Published on 7/9/2008

    Chiavolini D, Weir S, Murphy JR, Wetzler LM. Neisseria meningitidis PorB, a Toll-like receptor 2 ligand, improves the capacity of Francisella tularensis lipopolysaccharide to protect mice against experimental tularemia. Clin Vaccine Immunol. 2008 Sep; 15(9):1322-9. PMID: 18614668.

    Read at: PubMed
  • Published on 3/20/2008

    Tamayo AG, Bharti A, Trujillo C, Harrison R, Murphy JR. COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro. Proc Natl Acad Sci U S A. 2008 Apr 1; 105(13):5254-9. PMID: 18356299.

    Read at: PubMed

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