Hemant K. Roy, MD

Professor, Medicine

Hemant Roy
(617) 638-8345
650 Albany St Evans Biomed Research Ctr

Biography

Dr. Roy joined the faculty in 2013. He completed his medical degree from Northwestern University with distinction and completed internal medicine residency at Beth Isreal followed by GI Fellowship at University of Chicago.

Dr. Roy’s research interests center on GI cancer risk stratification using intermediate biomarkers of field carcinogenesis. He has been involved in the development and clinical implementation of a variety of biophotonic techniques for risk stratification encompassing both fiberoptic probes and cytological based techniques and these are complemented by a variety of molecular markers including microRNAs.

This has served as a platform for assessing risk modification via chemoprevention and applied to a number of non-GI malignancies including lung and ovarian cancer. Dr. Roy is a fellow of the American Gastroenterological Association and member of the Early Detection Research Network and the Cancer Biomarkers Study Section of the NCI,

More clinically, his interests are in high risk colon cancer syndromes and role of gender in colorectal cancer screening. Throughout his career he has also been involved in teaching receiving numerous awards in this regard.

Other Positions

  • Section Chief of Medicine in Gastroenterology, Gastroenterology, Medicine, Boston University School of Medicine

Education

  • Northwestern University School of Medicine, MD
  • Vanderbilt University, BS

Publications

  • Published on 5/5/2017

    Bauer GM, Stypula-Cyrus Y, Subramanian H, Cherkezyan L, Viswanathan P, Zhang D, Iyengar R, Bagalkar S, Derbas J, Graff T, Gladstein S, Almassalha LM, Chandler JE, Roy HK, Backman V. The transformation of the nuclear nanoarchitecture in human field carcinogenesis. Future Sci OA. 2017 Aug; 3(3):FSO206. PMID: 28884003.

    Read at: PubMed
  • Published on 3/28/2017

    Cruz MD, Ledbetter S, Chowdhury S, Tiwari AK, Momi N, Wali RK, Bliss C, Huang C, Lichtenstein D, Bhattacharya S, Varma-Wilson A, Backman V, Roy HK. Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis. Oncotarget. 2017 Mar 28; 8(13):20543-20557. PMID: 28423551.

    Read at: PubMed
  • Published on 2/16/2017

    Shao D, Han J, Hou X, Fry J, Behring JB, Seta F, Long MT, Roy HK, Cohen RA, Matsui R, Bachschmid MM. Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. Antioxid Redox Signal. 2017 Aug 20; 27(6):313-327. PMID: 27958883.

    Read at: PubMed
  • Published on 2/1/2017

    Drew DA, Chin SM, Gilpin KK, Parziale M, Pond E, Schuck MM, Stewart K, Flagg M, Rawlings CA, Backman V, Carolan PJ, Chung DC, Colizzo FP, Freedman M, Gala M, Garber JJ, Huttenhower C, Kedrin D, Khalili H, Kwon DS, Markowitz SD, Milne GL, Nishioka NS, Richter JM, Roy HK, Staller K, Wang M, Chan AT. ASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial. Trials. 2017 Feb 01; 18(1):50. PMID: 28143522.

    Read at: PubMed
  • Published on 1/24/2017

    Almassalha LM, Tiwari A, Ruhoff PT, Stypula-Cyrus Y, Cherkezyan L, Matsuda H, Dela Cruz MA, Chandler JE, White C, Maneval C, Subramanian H, Szleifer I, Roy HK, Backman V. The Global Relationship between Chromatin Physical Topology, Fractal Structure, and Gene Expression. Sci Rep. 2017 Jan 24; 7:41061. PMID: 28117353.

    Read at: PubMed
  • Published on 1/24/2017

    Krishn SR, Kaur S, Sheinin YM, Smith LM, Gautam SK, Patel A, Jain M, Juvvigunta V, Pai P, Lazenby AJ, Roy HK, Batra SK. Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance. Oncotarget. 2017 Jan 24; 8(4):7025-7038. PMID: 27705923.

    Read at: PubMed
  • Published on 1/1/2017

    Chowdhury S, Roy HK. The genetics and molecular biology of colonic neoplasia: practical implications for the clinician. Curr Opin Gastroenterol. 2017 Jan; 33(1):47-52. PMID: 27798442.

    Read at: PubMed
  • Published on 12/15/2016

    Calderwood AH, Lasser KE, Roy HK. Colon adenoma features and their impact on risk of future advanced adenomas and colorectal cancer. World J Gastrointest Oncol. 2016 Dec 15; 8(12):826-834. PMID: 28035253.

    Read at: PubMed
  • Published on 10/27/2016

    Wu W, Radosevich AJ, Eshein A, Nguyen TQ, Yi J, Cherkezyan L, Roy HK, Szleifer I, Backman V. Using electron microscopy to calculate optical properties of biological samples. Biomed Opt Express. 2016 Nov 01; 7(11):4749-4762. PMID: 27896013.

    Read at: PubMed
  • Published on 10/4/2016

    Almassalha LM, Bauer GM, Chandler JE, Gladstein S, Cherkezyan L, Stypula-Cyrus Y, Weinberg S, Zhang D, Thusgaard Ruhoff P, Roy HK, Subramanian H, Chandel NS, Szleifer I, Backman V. Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy. Proc Natl Acad Sci U S A. 2016 Oct 18; 113(42):E6372-E6381. PMID: 27702891.

    Read at: PubMed

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