Hemant K. Roy, MD

Professor, Medicine

Hemant Roy
617.638.8345
650 Albany St Evans Biomed Research Ctr

Biography

Dr. Roy joined the faculty in 2013. He completed his medical degree from Northwestern University with distinction and completed internal medicine residency at Beth Isreal followed by GI Fellowship at University of Chicago.

Dr. Roy’s research interests center on GI cancer risk stratification using intermediate biomarkers of field carcinogenesis. He has been involved in the development and clinical implementation of a variety of biophotonic techniques for risk stratification encompassing both fiberoptic probes and cytological based techniques and these are complemented by a variety of molecular markers including microRNAs.

This has served as a platform for assessing risk modification via chemoprevention and applied to a number of non-GI malignancies including lung and ovarian cancer. Dr. Roy is a fellow of the American Gastroenterological Association and member of the Early Detection Research Network and the Cancer Biomarkers Study Section of the NCI,

More clinically, his interests are in high risk colon cancer syndromes and role of gender in colorectal cancer screening. Throughout his career he has also been involved in teaching receiving numerous awards in this regard.

Other Positions

  • Section Chief of Medicine in Gastroenterology, Gastroenterology, Medicine, Boston University School of Medicine

Education

  • Northwestern University School of Medicine, MD
  • Vanderbilt University, BS

Publications

  • Published on 5/17/2018

    Kalman R, Stawarz A, Nunes D, Zhang D, Dela Cruz MA, Mohanty A, Subramanian H, Backman V, Roy HK. Biophotonic detection of high order chromatin alterations in field carcinogenesis predicts risk of future hepatocellular carcinoma: A pilot study. PLoS One. 2018; 13(5):e0197427. PMID: 29771950.

    Read at: PubMed
  • Published on 4/4/2018

    Wali RK, Bianchi L, Kupfer S, De La Cruz M, Jovanovic B, Weber C, Goldberg MJ, Rodriguez LM, Bergan R, Rubin D, Tull MB, Richmond E, Parker B, Khan S, Roy HK. Prevention of colonic neoplasia with polyethylene glycol: A short term randomized placebo-controlled double-blinded trial. PLoS One. 2018; 13(4):e0193544. PMID: 29617381.

    Read at: PubMed
  • Published on 3/23/2018

    Mohapatra SS, Batra SK, Bharadwaj S, Bouvet M, Cosman B, Goel A, Jogunoori W, Kelley MJ, Mishra L, Mishra B, Mohapatra S, Patel B, Pisegna JR, Raufman JP, Rao S, Roy H, Scheuner M, Singh S, Vidyarthi G, White J. Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions. Dig Dis Sci. 2018 05; 63(5):1123-1138. PMID: 29572615.

    Read at: PubMed
  • Published on 3/23/2018

    Gladstein S, Damania D, Almassalha LM, Smith LT, Gupta V, Subramanian H, Rex DK, Roy HK, Backman V. Correlating colorectal cancer risk with field carcinogenesis progression using partial wave spectroscopic microscopy. Cancer Med. 2018 May; 7(5):2109-2120. PMID: 29573208.

    Read at: PubMed
  • Published on 2/19/2018

    Datta S, Sherva RM, De La Cruz M, Long MT, Roy P, Backman V, Chowdhury S, Roy HK. Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities. Neoplasia. 2018 Mar; 20(3):289-294. PMID: 29471289.

    Read at: PubMed
  • Published on 1/10/2018

    Roy P, Chowdhury S, Roy HK. Exercise-induced myokines as emerging therapeutic agents in colorectal cancer prevention and treatment. Future Oncol. 2018 02; 14(4):309-312. PMID: 29318900.

    Read at: PubMed
  • Published on 11/6/2017

    Almassalha LM, Bauer GM, Wu W, Cherkezyan L, Zhang D, Kendra A, Gladstein S, Chandler JE, VanDerway D, Seagle BL, Ugolkov A, Billadeau DD, O'Halloran TV, Mazar AP, Roy HK, Szleifer I, Shahabi S, Backman V. Macrogenomic engineering via modulation of the scaling of chromatin packing density. Nat Biomed Eng. 2017 Nov; 1(11):902-913. PMID: 29450107.

    Read at: PubMed
  • Published on 5/5/2017

    Bauer GM, Stypula-Cyrus Y, Subramanian H, Cherkezyan L, Viswanathan P, Zhang D, Iyengar R, Bagalkar S, Derbas J, Graff T, Gladstein S, Almassalha LM, Chandler JE, Roy HK, Backman V. The transformation of the nuclear nanoarchitecture in human field carcinogenesis. Future Sci OA. 2017 Aug; 3(3):FSO206. PMID: 28884003.

    Read at: PubMed
  • Published on 3/28/2017

    Cruz MD, Ledbetter S, Chowdhury S, Tiwari AK, Momi N, Wali RK, Bliss C, Huang C, Lichtenstein D, Bhattacharya S, Varma-Wilson A, Backman V, Roy HK. Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis. Oncotarget. 2017 Mar 28; 8(13):20543-20557. PMID: 28423551.

    Read at: PubMed
  • Published on 2/16/2017

    Shao D, Han J, Hou X, Fry J, Behring JB, Seta F, Long MT, Roy HK, Cohen RA, Matsui R, Bachschmid MM. Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. Antioxid Redox Signal. 2017 Aug 20; 27(6):313-327. PMID: 27958883.

    Read at: PubMed

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