Chunlei Zheng, PhD
Assistant Professor, Medicine
Biography
Chunlei Zheng is an Assistant Professor of Medicine at Chobanian and Avedisian School of Medicine. He is also a Health Science Specialist at VA Boston Healthcare System. Dr. Zheng completed his PhD in Biophysics at Chinese Academy of Sciences. After graduation, he moved to Cleveland Clinic, where he received a postdoctoral fellowship from American Heart Association to study the protein trafficking in human diseases. Before joining Boston University, Dr. Zheng is a research scientist at Case Western Reserve University, where he received intensive biomedical informatics training.
With solid background in biology and medicine and expertise in genomics, computer science, and statistics, Dr. Zheng has great passion for data-driven biomedical discovery. In particular, he has great interest on developing/applying computational algorithm, machine learning and statistical modeling into large-scale biomedical data to facilitate disease understanding and drug discovery. Currently, his research focuses on using artificial intelligence (AI) on Alzheimer’s Disease and Cancer.
Websites
Education
- Chinese Academy of Sciences, PhD
- Shaanxi Normal University, BS
Publications
- Published on 1/25/2024
Do NV, Elbers DC, Fillmore NR, Ajjarapu S, Bergstrom SJ, Bihn J, Corrigan JK, Dhond R, Dipietro S, Dolgin A, Feldman TC, Goryachev SD, Huhmann LB, La J, Marcantonio PA, McGrath KM, Miller SJ, Nguyen VQ, Schneeloch GR, Sung FC, Swinnerton KN, Tarren AH, Tosi HM, Valley D, Vo AD, Yildirim C, Zheng C, Zwolinski R, Sarosy GA, Loose D, Shannon C, Brophy MT. Matching Patients to Accelerate Clinical Trials (MPACT): Enabling Technology for Oncology Clinical Trial Workflow. Stud Health Technol Inform. 2024 Jan 25; 310:1086-1090. PMID: 38269982.
Read at: PubMed - Published on 7/10/2023
Chen C, Luo L, Zheng C, Ding P, Liu H, Luo H. Self-prediction of relations in GO facilitates its quality auditing. J Biomed Inform. 2023 Aug; 144:104441. PMID: 37437682.
Read at: PubMed - Published on 5/8/2023
Placido D, Yuan B, Hjaltelin JX, Zheng C, Haue AD, Chmura PJ, Yuan C, Kim J, Umeton R, Antell G, Chowdhury A, Franz A, Brais L, Andrews E, Marks DS, Regev A, Ayandeh S, Brophy MT, Do NV, Kraft P, Wolpin BM, Rosenthal MH, Fillmore NR, Brunak S, Sander C. A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories. Nat Med. 2023 May; 29(5):1113-1122. PMID: 37156936.
Read at: PubMed - Published on 4/26/2022
Ramos-Cejudo J, Johnson AD, Beiser A, Seshadri S, Salinas J, Berger JS, Fillmore NR, Do N, Zheng C, Kovbasyuk Z, Ardekani BA, Nunzio P, Bubu OM, Parekh A, Convit A, Betensky RA, Wisniewski TM, Osorio RS. Platelet Function Is Associated With Dementia Risk in the Framingham Heart Study. J Am Heart Assoc. 2022 May 03; 11(9):e023918. PMID: 35470685.
Read at: PubMed - Published on 4/14/2022
Zhang Y, Zhu M, Zheng C, Wei W, Emmer BT, Zhang B. LMAN1-MCFD2 complex is a cargo receptor for the ER-Golgi transport of a1-antitrypsin. Biochem J. 2022 Apr 14; 479(7):839-855. PMID: 35322856.
Read at: PubMed - Published on 1/19/2022
Li LL, Zheng C, La J, Do NV, Monach PA, Strymish JM, Fillmore NR, Branch-Elliman W. Impact of prior SARS-CoV-2 infection on incidence of hospitalization and adverse events following mRNA SARS-CoV-2 vaccination: A nationwide, retrospective cohort study. Vaccine. 2022 02 16; 40(8):1082-1089. PMID: 35078665.
Read at: PubMed - Published on 1/11/2022
Fillmore NR, La J, Zheng C, Doron S, Do NV, Monach PA, Branch-Elliman W. The COVID-19 hospitalization metric in the pre- and postvaccination eras as a measure of pandemic severity: A retrospective, nationwide cohort study. Infect Control Hosp Epidemiol. 2022 Dec; 43(12):1767-1772. PMID: 35012694.
Read at: PubMed - Published on 11/30/2021
Ramos-Cejudo J, Johnson AD, Beiser A, Seshadri S, Salinas J, Berger JS, Fillmore NR, Do N, Zheng C, Kovbasyuk Z, Ardekani BA, Bubu OM, Parekh A, Convit A, Betensky RA, Wisniewski TM, Osorio RS. The Neutrophil to Lymphocyte Ratio Is Associated With the Risk of Subsequent Dementia in the Framingham Heart Study. Front Aging Neurosci. 2021; 13:773984. PMID: 34916927.
Read at: PubMed - Published on 9/27/2021
Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R. Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimers Dement. 2022 Jun; 18(6):1248-1259. PMID: 34569707.
Read at: PubMed - Published on 5/20/2021
Zheng C, Xu R. Molecular subtyping of Alzheimer's disease with consensus non-negative matrix factorization. PLoS One. 2021; 16(5):e0250278. PMID: 34014928.
Read at: PubMed
View 25 more publications: View full profile at BUMC